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OrbiMed Advisors LLC

SEC CIK
0001055951
Latest filing
Aug 14, 2026

Holdings in Q3 2023

Holdings as of Sep 30, 2023, filed Nov 14, 2023. Long positions only; changes compare share counts with Q2 2023.

Institution overview
Positions
120
+1 vs. Q2 2023
Portfolio value
$4.32B
−$816.9M (−15.9%) vs. Q2 2023
Filed
Nov 14, 2023
SEC
Holdings of OrbiMed Advisors LLC in Q3 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
EVHEvolent Health, Inc.CL A2,895,632$78.8M1.8%00.0%UnchangedHistory
XTNTXtant Medical Holdings, Inc.COM NEW73,114,592$80.4M1.9%00.0%UnchangedHistory
THCTenet Healthcare CorpCOM NEW1,224,400$80.7M1.9%+263,900+27.5%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM14,567,176$83.5M1.9%00.0%UnchangedHistory
BAXBaxter International IncStock2,239,900$84.5M2.0%−1,135,100−33.6%ReducedHistory
MRTXMirati Therapeutics, Inc.COM1,959,050$85.3M2.0%+1,045,400+114.4%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM2,896,074$86.1M2.0%−1,054,722−26.7%ReducedHistory
UTHRUnited Therapeutics CorpCOM401,900$90.8M2.1%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM3,968,588$91.8M2.1%−210,000−5.0%ReducedHistory
IONSIonis Pharmaceuticals IncCOM2,169,500$98.4M2.3%00.0%UnchangedHistory
LLYEli Lilly & CoStock186,000$99.9M2.3%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM2,269,637$106.6M2.5%00.0%UnchangedHistory
MRKMerck & Co., Inc.Stock1,055,000$108.6M2.5%+1,055,000NewHistory
ELVNEnliven Therapeutics, Inc.COM8,998,338$122.9M2.8%00.0%UnchangedHistory
BMRNBiomarin Pharmaceutical IncCOM1,615,210$142.9M3.3%00.0%UnchangedHistory
BIIBBiogen Inc.COM556,800$143.1M3.3%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW499,000$145.9M3.4%−121,500−19.6%ReducedHistory
HUMHumana IncStock342,500$166.6M3.9%−6,200−1.8%ReducedHistory
BSXBoston Scientific CorpStock3,306,800$174.6M4.0%−73,100−2.2%ReducedHistory
SVASinovac Biotech LtdSHS2,718,735––00.0%UnchangedHistory

Options (7)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of OrbiMed Advisors LLC in Q3 2023
SecurityClassPutsCalls
AZNAstraZeneca PLCSPONSORED ADR–$16.9M
SGENSeagen Inc.COM–$10.6M
KVUEKenvue Inc.Stock–$5.02M
DXCMDexcom IncCOM–$4.67M
MRTXMirati Therapeutics, Inc.COM–$4.36M
APLSApellis Pharmaceuticals, Inc.COM–$2.95M
IMTXImmatics N.V.SHS–$1.45M

Sold out since Q2 2023 (13)

Positions held at the end of Q2 2023 that are gone from this filing.

Positions of OrbiMed Advisors LLC sold out since Q2 2023
SecurityClassShares in Q2 2023Value in Q2 2023% of portfolio in Q2 2023History
BMYBristol Myers Squibb CoStock1,488,000$95.2M1.9%History
Vectivbio Hldg AGH9060V101ORD SHS5,156,561$87.7M1.7%–
EWEdwards Lifesciences CorpStock515,000$48.6M0.9%History
ZBHZimmer Biomet Holdings, Inc.Stock245,000$35.7M0.7%History
TVTXTravere Therapeutics, Inc.COM2,118,100$32.5M0.6%History
TSVT2seventy bio, Inc.COMMON STOCK2,391,628$24.2M0.5%History
MRSNMersana Therapeutics, Inc.COM7,214,937$23.7M0.5%History
FOLDAmicus Therapeutics, Inc.COM1,856,400$23.3M0.5%History
DBTXDecibel Therapeutics, Inc.COM4,945,192$19.0M0.4%History
BridgeBio Pharma, Inc.10806XAD4NOTE 2.250% 2/0–$9.27M0.2%–
GHRSGH Research PLCORDINARY SHARES736,315$8.74M0.2%History
ALKSAlkermes plc.SHS151,400$4.74M0.1%History
RVNCRevance Therapeutics, Inc.COM100,000$2.53M<0.1%History