| Capital Research Global Investors | 8,026,903 | $5.98 億 | 0.15% | – | – |
| Vanguard Group Inc | 7,366,100 | $5.49 億 | 0.01% | – | – |
| Janus Henderson Group PLC | 6,171,863 | $4.60 億 | 0.21% | – | – |
| BlackRock Inc. | 5,513,550 | $4.11 億 | 0.01% | – | – |
| FMR LLC | 4,429,653 | $3.30 億 | 0.03% | – | – |
| Sands Capital Management, LLC | 3,028,090 | $2.26 億 | 0.44% | – | – |
| Avoro Capital Advisors LLC | 2,150,000 | $1.60 億 | 2.77% | – | – |
| State Street Corp | 2,031,305 | $1.51 億 | 0.01% | – | – |
| ARK Investment Management LLC大師方舟投資 | 1,860,293 | $1.39 億 | 0.28% | – | – |
| Bank of New York Mellon Corp | 1,791,294 | $1.34 億 | 0.03% | – | – |
| Wellington Management Group LLP | 1,517,674 | $1.13 億 | 0.02% | – | – |
| Ameriprise Financial Inc | 1,140,293 | $8,499 萬 | 0.03% | – | – |
| Geode Capital Management, LLC | 969,763 | $7,219 萬 | 0.01% | – | – |
| First Trust Advisors LP | 885,871 | $6,602 萬 | 0.08% | – | – |
| JPMorgan Chase & Co | 753,598 | $5,617 萬 | 0.01% | – | – |
| Goldman Sachs Group Inc | 714,412 | $5,325 萬 | 0.02% | – | – |
| Price T Rowe Associates Inc | 704,153 | $5,248 萬 | 0.01% | – | – |
| Eventide Asset Management, LLC | 697,156 | $5,196 萬 | 0.77% | – | – |
| Norges Bank | 674,002 | $5,023 萬 | 0.01% | – | – |
| Erste Asset Management GmbH | 641,560 | $4,778 萬 | 1.17% | – | – |
| Credit Suisse AG | 605,850 | $4,515 萬 | 0.03% | – | – |
| Casdin Capital, LLC | 550,000 | $4,099 萬 | 1.22% | – | – |
| Voloridge Investment Management, LLC | 531,955 | $3,965 萬 | 0.29% | – | – |
| Bank of America Corp | 517,016 | $3,853 萬 | 0.00% | – | – |
| Deutsche Bank AG | 509,715 | $3,799 萬 | 0.02% | – | – |
| Northern Trust Corp | 482,802 | $3,598 萬 | 0.01% | – | – |
| Sumitomo Mitsui Trust Holdings, Inc. | 447,155 | $3,333 萬 | 0.02% | – | – |
| Marshall Wace North America L.P. | 416,150 | $3,102 萬 | 0.13% | – | – |
| Legal & General Group Plc | 413,363 | $3,081 萬 | 0.01% | – | – |
| Charles Schwab Investment Management Inc | 394,432 | $2,940 萬 | 0.01% | – | – |
| Nuveen Asset Management, LLC | 380,993 | $2,840 萬 | 0.01% | – | – |
| Tobam | 371,107 | $2,766 萬 | 1.18% | – | – |
| Millennium Management LLC | 370,183 | $2,759 萬 | 0.04% | – | – |
| Candriam Luxembourg S.C.A. | 164,008 | $2,686 萬 | 0.22% | – | – |
| Rock Springs Capital Management LP | 328,750 | $2,450 萬 | 0.53% | – | – |
| Farallon Capital Management, L.L.C. | 300,000 | $2,236 萬 | 0.12% | – | – |
| Swiss National Bank | 287,173 | $2,140 萬 | 0.01% | – | – |
| Pictet Asset Management Ltd | 282,085 | $2,102 萬 | 0.03% | – | – |
| Federated Hermes, Inc. | 281,535 | $2,098 萬 | 0.04% | – | – |
| Citadel Advisors LLC | 245,871 | $1,833 萬 | 0.02% | – | – |
| Susquehanna International Group, LLP | 241,520 | $1,800 萬 | 0.02% | – | – |
| UBS Asset Management Americas Inc | 205,042 | $1,528 萬 | 0.01% | – | – |
| OrbiMed Advisors LLC | 200,278 | $1,493 萬 | 0.14% | – | – |
| Nikko Asset Management Americas, Inc. | 192,650 | $1,436 萬 | 0.07% | – | – |
| Morgan Stanley | 192,601 | $1,435 萬 | 0.00% | – | – |
| Korea Investment CORP | 190,841 | $1,422 萬 | 0.04% | – | – |
| Dimensional Fund Advisors LP | 176,362 | $1,316 萬 | 0.00% | – | – |
| California Public Employees Retirement System | 169,164 | $1,261 萬 | 0.01% | – | – |
| Waddell & Reed Financial Inc | 168,640 | $1,257 萬 | 0.03% | – | – |
| Jane Street Group, LLC | 167,546 | $1,249 萬 | 0.04% | – | – |
| APG Asset Management N.V. | 181,440 | $1,151 萬 | 0.02% | – | – |
| Group One Trading, L.P. | 152,538 | $1,137 萬 | 0.25% | – | – |
| California State Teachers Retirement System | 141,889 | $1,058 萬 | 0.01% | – | – |
| Point72 Asset Management, L.P. | 138,986 | $1,036 萬 | 0.05% | – | – |
| Tekla Capital Management LLC | 128,987 | $961.3 萬 | 0.33% | – | – |
| C WorldWide Group Holding A/S | 120,329 | $896.8 萬 | 0.09% | – | – |
| Parametric Portfolio Associates LLC | 110,510 | $823.6 萬 | 0.00% | – | – |
| Pinnacle Associates Ltd | 110,496 | $823.5 萬 | 0.16% | – | – |
| State Board of Administration of Florida Retirement System | 102,537 | $764.2 萬 | 0.02% | – | – |
| AXA S.A. | 101,989 | $760.1 萬 | 0.02% | – | – |
| Cubist Systematic Strategies, LLC | 96,502 | $719.2 萬 | 0.09% | – | – |
| Invesco Ltd. | 95,598 | $712.5 萬 | 0.00% | – | – |
| Wells Fargo & Company | 94,880 | $707.1 萬 | 0.00% | – | – |
| Citigroup Inc | 94,386 | $703.5 萬 | 0.01% | – | – |
| Jacobs Levy Equity Management, Inc | 88,997 | $663.3 萬 | 0.05% | – | – |
| New York State Common Retirement Fund | 88,300 | $658.1 萬 | 0.01% | – | – |
| UBS Group AG | 87,200 | $649.9 萬 | 0.00% | – | – |
| Two Sigma Investments, LP | 86,267 | $642.9 萬 | 0.02% | – | – |
| Rhumbline Advisers | 78,342 | $583.9 萬 | 0.01% | – | – |
| Storebrand Asset Management AS | 77,376 | $576.7 萬 | 0.03% | – | – |
| Worldquant Millennium Advisors LLC | 73,970 | $551.3 萬 | 0.12% | – | – |
| Cormorant Asset Management, LP | 70,000 | $521.7 萬 | 0.15% | – | – |
| Evolutionary Tree Capital Management, LLC | 68,937 | $513.8 萬 | 3.04% | – | – |
| State of Wisconsin Investment Board | 64,271 | $479.0 萬 | 0.01% | – | – |
| Jennison Associates LLC | 62,133 | $463.1 萬 | 0.00% | – | – |
| Squarepoint Ops LLC | 61,187 | $456.0 萬 | 0.04% | – | – |
| Baker Bros. Advisors LP | 58,700 | $437.5 萬 | 0.02% | – | – |
| Royal Bank of Canada | 56,685 | $422.5 萬 | 0.00% | – | – |
| Mirae Asset Global Investments Co., Ltd. | 56,303 | $419.7 萬 | 0.01% | – | – |
| Barclays PLC | 53,886 | $401.5 萬 | 0.00% | – | – |
| Caas Capital Management LP | 53,478 | $398.6 萬 | 0.12% | – | – |
| Great West Life Assurance Co | 53,720 | $397.9 萬 | 0.01% | – | – |
| Amundi Asset Management US, Inc. | 52,928 | $394.4 萬 | 0.00% | – | – |
| State of New Jersey Common Pension Fund D | 49,624 | $369.8 萬 | 0.01% | – | – |
| Alliancebernstein L.P. | 48,465 | $361.2 萬 | 0.00% | – | – |
| Thrivent Financial for Lutherans | 45,044 | $335.7 萬 | 0.01% | – | – |
| Mitsubishi UFJ Trust & Banking Corp | 43,769 | $330.5 萬 | 0.01% | – | – |
| BNP Paribas Arbitrage, SA | 43,449 | $323.8 萬 | 0.01% | – | – |
| TD Asset Management Inc | 41,821 | $311.7 萬 | 0.00% | – | – |
| Guggenheim Capital LLC | 41,646 | $310.3 萬 | 0.02% | – | – |
| Public Employees Retirement System of Ohio | 40,004 | $298.1 萬 | 0.01% | – | – |
| DekaBank Deutsche Girozentrale | 39,990 | $291.2 萬 | 0.01% | – | – |
| Rafferty Asset Management, LLC | 38,524 | $287.1 萬 | 0.02% | – | – |
| Sit Investment Associates Inc | 38,090 | $283.9 萬 | 0.07% | – | – |
| DnB Asset Management AS | 38,014 | $283.3 萬 | 0.02% | – | – |
| Balyasny Asset Management LLC | 37,907 | $282.5 萬 | 0.02% | – | – |
| Wolverine Trading, LLC | 38,609 | $282.2 萬 | 0.05% | – | – |
| Money Concepts Capital Corp | 37,274 | $277.8 萬 | 0.22% | – | – |
| Russell Investments Group, Ltd. | 36,884 | $274.1 萬 | 0.00% | – | – |
| ExodusPoint Capital Management, LP | 36,488 | $271.9 萬 | 0.05% | – | – |
