| Nicholas Investment Partners, LP | 168,284 | $2,218 萬 | 1.55% | – | – |
| Tekla Capital Management LLC | 167,302 | $2,205 萬 | 0.76% | – | – |
| Blue Water Life Science Advisors, LLC | 166,957 | $2,200 萬 | 10.75% | – | – |
| Rhumbline Advisers | 155,439 | $2,048 萬 | 0.03% | – | – |
| William Blair Investment Management, LLC | 151,410 | $1,995 萬 | 0.06% | – | – |
| Scout Investments, Inc. | 148,246 | $1,954 萬 | 0.29% | – | – |
| Compagnie Lombard Odier SCmA | 147,060 | $1,938 萬 | 0.43% | – | – |
| Worldquant Millennium Advisors LLC | 146,033 | $1,924 萬 | 0.41% | – | – |
| Tobam | 142,560 | $1,879 萬 | 0.80% | – | – |
| Royal Bank of Canada | 142,398 | $1,877 萬 | 0.01% | – | – |
| Empire Life Investments Inc. | 139,106 | $1,833 萬 | 1.26% | – | – |
| SEI Investments Co | 136,354 | $1,798 萬 | 0.05% | – | – |
| Skandinaviska Enskilda Banken AB (publ) | 133,015 | $1,753 萬 | 0.12% | – | – |
| State of Michigan Retirement System | 132,204 | $1,742 萬 | 0.11% | – | – |
| Beacon Investment Advisory Services, Inc. | 125,990 | $1,660 萬 | 0.72% | – | – |
| US Bancorp | 118,547 | $1,562 萬 | 0.03% | – | – |
| Thompson Investment Management, Inc. | 115,966 | $1,528 萬 | 2.31% | – | – |
| Rothschild & Co Asset Management US Inc. | 110,047 | $1,450 萬 | 0.18% | – | – |
| Jefferies Group LLC | 106,800 | $1,407 萬 | 0.33% | – | – |
| RiverPark Advisors, LLC | 106,155 | $1,399 萬 | 2.31% | – | – |
| Sands Capital Management, LLC | 103,296 | $1,361 萬 | 0.03% | – | – |
| Great West Life Assurance Co | 102,488 | $1,342 萬 | 0.03% | – | – |
| Edmond de Rothschild Holding S.A. | 101,594 | $1,339 萬 | 0.37% | – | – |
| Two Sigma Investments, LP | 100,582 | $1,326 萬 | 0.04% | – | – |
| LPL Financial LLC | 100,496 | $1,324 萬 | 0.02% | – | – |
| Iron Triangle Partners LP | 100,000 | $1,318 萬 | 1.68% | – | – |
| Stifel Financial Corp | 99,795 | $1,315 萬 | 0.02% | – | – |
| Allianz Asset Management GmbH | 99,205 | $1,307 萬 | 0.01% | – | – |
| American National Insurance Co | 99,125 | $1,306 萬 | 0.53% | – | – |
| CWM, LLC | 104,633 | $1,301 萬 | 0.10% | – | – |
| Moody National Bank Trust Division | 98,100 | $1,293 萬 | 0.31% | – | – |
| Biondo Investment Advisors, LLC | 96,686 | $1,274 萬 | 2.54% | – | – |
| Lazard Asset Management LLC | 96,417 | $1,271 萬 | 0.02% | – | – |
| State of New Jersey Common Pension Fund D | 96,263 | $1,269 萬 | 0.04% | – | – |
| Erste Asset Management GmbH | 95,900 | $1,246 萬 | 0.30% | – | – |
| Pictet & Cie (Europe) SA | 92,448 | $1,218 萬 | 0.49% | – | – |
| Barclays PLC | 90,679 | $1,195 萬 | 0.01% | – | – |
| Citadel Advisors LLC | 90,453 | $1,192 萬 | 0.01% | – | – |
| HighTower Advisors, LLC | 87,324 | $1,151 萬 | 0.04% | – | – |
| Pictet North America Advisors SA | 86,875 | $1,145 萬 | 1.34% | – | – |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 86,738 | $1,143 萬 | 0.02% | – | – |
| Resources Investment Advisors, LLC. | 85,614 | $1,128 萬 | 0.53% | – | – |
| Alliancebernstein L.P. | 84,387 | $1,112 萬 | 0.00% | – | – |
| Jane Street Group, LLC | 82,997 | $1,094 萬 | 0.03% | – | – |
| Renaissance Technologies LLC | 82,904 | $1,093 萬 | 0.01% | – | – |
| BNP Paribas Arbitrage, SA | 82,221 | $1,084 萬 | 0.02% | – | – |
| Public Employees Retirement System of Ohio | 80,272 | $1,058 萬 | 0.04% | – | – |
| State of Wisconsin Investment Board | 75,064 | $989.2 萬 | 0.02% | – | – |
| Asset Management One Co.,Ltd. | 71,755 | $945.5 萬 | 0.04% | – | – |
| Storebrand Asset Management AS | 71,001 | $935.7 萬 | 0.05% | – | – |
| Heritage Investors Management Corp | 70,391 | $927.6 萬 | 0.41% | – | – |
| Great Lakes Advisors, LLC | 70,368 | $927.3 萬 | 0.15% | – | – |
| Atika Capital Management LLC | 70,000 | $922.5 萬 | 0.96% | – | – |
| Northeast Investment Management | 69,858 | $920.6 萬 | 0.54% | – | – |
| Franklin Resources Inc | 68,245 | $899.4 萬 | 0.00% | – | – |
| Susquehanna Fundamental Investments, LLC | 68,171 | $898.4 萬 | 0.15% | – | – |
| Treasurer of the State of North Carolina | 67,277 | $886.6 萬 | 0.06% | – | – |
| PEAK6 Investments LLC | 64,856 | $854.7 萬 | 0.22% | – | – |
| Mirae Asset Global Investments Co., Ltd. | 64,429 | $849.1 萬 | 0.03% | – | – |
| Janus Henderson Group PLC | 60,202 | $793.3 萬 | 0.00% | – | – |
| Ergoteles LLC | 59,782 | $787.8 萬 | 0.25% | – | – |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 58,900 | $776.2 萬 | 0.07% | – | – |
| Raymond James & Associates | 58,301 | $768.3 萬 | 0.01% | – | – |
| Pictet Asset Management Ltd | 57,300 | $755.1 萬 | 0.01% | – | – |
| Guggenheim Capital LLC | 55,592 | $732.6 萬 | 0.05% | – | – |
| Sectoral Asset Management Inc | 55,000 | $724.8 萬 | 0.55% | – | – |
| Royal London Asset Management Ltd | 54,470 | $717.8 萬 | 0.03% | – | – |
| Bank of Montreal | 54,256 | $697.3 萬 | 0.00% | – | – |
| R.H. Dinel Investment Counsel, Inc. | 52,900 | $697.1 萬 | 5.32% | – | – |
| Commonwealth Equity Services, LLC | 52,854 | $696.5 萬 | 0.02% | – | – |
| Handelsinvest Investeringsforvaltning | 52,500 | $691.8 萬 | 0.84% | – | – |
| RMB Capital Management, LLC | 51,941 | $684.5 萬 | 0.25% | – | – |
| Bokf, NA | 50,884 | $670.6 萬 | 0.12% | – | – |
| Aviva PLC | 49,277 | $649.4 萬 | 0.03% | – | – |
| Sit Investment Associates Inc | 48,500 | $639.1 萬 | 0.17% | – | – |
| Driehaus Capital Management LLC | 48,000 | $632.5 萬 | 0.09% | – | – |
| Qci Asset Management Inc | 47,741 | $629.1 萬 | 0.39% | – | – |
| Marco Investment Management LLC | 46,078 | $607.2 萬 | 0.79% | – | – |
| Arizona State Retirement System | 45,852 | $604.2 萬 | 0.05% | – | – |
| Raymond James Financial Services Advisors, Inc. | 43,821 | $577.5 萬 | 0.01% | – | – |
| Marsico Capital Management LLC | 43,786 | $577.0 萬 | 0.15% | – | – |
| Riverpark Capital Management LLC | 42,752 | $563.3 萬 | 2.53% | – | – |
| AMP Capital Investors Ltd | 41,716 | $547.1 萬 | 0.03% | – | – |
| Group One Trading, L.P. | 41,172 | $542.6 萬 | 0.12% | – | – |
| USS Investment Management Ltd | 41,023 | $540.6 萬 | 0.05% | – | – |
| Harbour Investments, Inc. | 39,455 | $519.9 萬 | 0.19% | – | – |
| Cinctive Capital Management LP | 39,012 | $514.1 萬 | 0.33% | – | – |
| Natixis Advisors, L.P. | 39,002 | $513.9 萬 | 0.03% | – | – |
| HSBC Holdings PLC | 37,696 | $490.5 萬 | 0.01% | – | – |
| NN Investment Partners Holdings N.V. | 36,904 | $486.3 萬 | 0.03% | – | – |
| Brown Advisory Inc | 35,471 | $467.3 萬 | 0.01% | – | – |
| Scotia Capital Inc. | 34,133 | $449.8 萬 | 0.04% | – | – |
| Tower Research Capital LLC (TRC) | 33,424 | $440.5 萬 | 0.07% | – | – |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 33,258 | $438.3 萬 | 0.03% | – | – |
| DekaBank Deutsche Girozentrale | 35,230 | $434.9 萬 | 0.01% | – | – |
| Grandeur Peak Global Advisors, LLC | 32,633 | $430.0 萬 | 0.23% | – | – |
| DnB Asset Management AS | 32,461 | $427.8 萬 | 0.03% | – | – |
| Credit Agricole S A | 31,910 | $420.5 萬 | 0.16% | – | – |
| KBC Group NV | 31,907 | $420.5 萬 | 0.02% | – | – |
| Edgestream Partners, L.P. | 31,692 | $417.6 萬 | 0.23% | – | – |
