| Price T Rowe Associates Inc | 18,293,939 | $24.1 億 | 0.24% | – | – |
| Vanguard Group Inc | 15,103,423 | $19.9 億 | 0.05% | – | – |
| ARK Investment Management LLC大師方舟投資 | 9,148,635 | $12.1 億 | 2.39% | – | – |
| BlackRock Inc. | 9,002,413 | $11.9 億 | 0.04% | – | – |
| Capital World Investors | 8,407,786 | $11.1 億 | 0.20% | – | – |
| JPMorgan Chase & Co | 5,160,834 | $6.80 億 | 0.10% | – | – |
| Baillie Gifford & Co | 4,347,026 | $5.73 億 | 0.32% | – | – |
| Wellington Management Group LLP | 3,626,651 | $4.78 億 | 0.08% | – | – |
| State Street Corp | 3,340,479 | $4.40 億 | 0.03% | – | – |
| Ameriprise Financial Inc | 3,222,875 | $4.25 億 | 0.14% | – | – |
| Artisan Partners Limited Partnership | 2,701,669 | $3.56 億 | 0.46% | – | – |
| Sumitomo Mitsui Trust Holdings, Inc. | 2,676,187 | $3.53 億 | 0.22% | – | – |
| Casdin Capital, LLC | 2,360,186 | $3.11 億 | 9.26% | – | – |
| Macquarie Group Ltd | 2,242,071 | $2.95 億 | 0.42% | – | – |
| Nikko Asset Management Americas, Inc. | 2,198,130 | $2.90 億 | 1.42% | – | – |
| Invesco Ltd. | 2,054,061 | $2.71 億 | 0.07% | – | – |
| Voya Investment Management LLC | 1,951,669 | $2.57 億 | 0.52% | – | – |
| Geode Capital Management, LLC | 1,940,577 | $2.55 億 | 0.04% | – | – |
| Zevenbergen Capital Investments LLC | 1,857,861 | $2.45 億 | 4.65% | – | – |
| Credit Suisse AG | 1,822,534 | $2.40 億 | 0.18% | – | – |
| Ensign Peak Advisors, Inc | 1,759,655 | $2.32 億 | 0.50% | – | – |
| Eventide Asset Management, LLC | 1,740,000 | $2.29 億 | 3.40% | – | – |
| Spyglass Capital Management LLC | 1,543,155 | $2.03 億 | 5.36% | – | – |
| Amundi Asset Management US, Inc. | 1,507,798 | $1.99 億 | 0.15% | – | – |
| Morgan Stanley | 1,475,794 | $1.94 億 | 0.03% | – | – |
| Gilder Gagnon Howe & Co LLC | 1,468,801 | $1.94 億 | 1.04% | – | – |
| Norges Bank | 1,326,215 | $1.75 億 | 0.04% | – | – |
| Bank of America Corp | 1,197,119 | $1.58 億 | 0.02% | – | – |
| Northern Trust Corp | 989,673 | $1.30 億 | 0.02% | – | – |
| FMR LLC | 966,768 | $1.27 億 | 0.01% | – | – |
| Suvretta Capital Management, LLC | 886,940 | $1.17 億 | 1.74% | – | – |
| Natixis | 871,142 | $1.15 億 | 0.38% | – | – |
| Nuveen Asset Management, LLC | 867,677 | $1.14 億 | 0.04% | – | – |
| Legal & General Group Plc | 866,272 | $1.14 億 | 0.04% | – | – |
| First Trust Advisors LP | 846,227 | $1.12 億 | 0.14% | – | – |
| Swedbank AB | 818,731 | $1.08 億 | 0.22% | – | – |
| Goldman Sachs Group Inc | 759,011 | $1.00 億 | 0.03% | – | – |
| Frontier Capital Management Co LLC | 756,536 | $9,970 萬 | 0.75% | – | – |
| Eminence Capital, LP | 750,088 | $9,885 萬 | 1.22% | – | – |
| Blair William & Co | 724,889 | $9,553 萬 | 0.36% | – | – |
| New York State Common Retirement Fund | 618,330 | $8,148 萬 | 0.09% | – | – |
| Swiss National Bank | 611,624 | $8,060 萬 | 0.05% | – | – |
| Avidity Partners Management LP | 598,000 | $7,880 萬 | 2.20% | – | – |
| Primecap Management Co | 584,800 | $7,707 萬 | 0.05% | – | – |
| Bank of New York Mellon Corp | 578,963 | $7,630 萬 | 0.02% | – | – |
| Rock Springs Capital Management LP | 570,000 | $7,512 萬 | 1.64% | – | – |
| Victory Capital Management Inc | 568,605 | $7,493 萬 | 0.08% | – | – |
| Deutsche Bank AG | 564,000 | $7,432 萬 | 0.04% | – | – |
| UBS Asset Management Americas Inc | 550,053 | $7,249 萬 | 0.03% | – | – |
| Charles Schwab Investment Management Inc | 500,279 | $6,593 萬 | 0.02% | – | – |
| Factory Mutual Insurance Co | 468,236 | $6,170 萬 | 0.79% | – | – |
| D. E. Shaw & Co., Inc. | 445,381 | $5,869 萬 | 0.07% | – | – |
| Putnam Investments LLC | 414,561 | $5,463 萬 | 0.09% | – | – |
| Eagle Asset Management Inc | 393,949 | $5,223 萬 | 0.23% | – | – |
| Principal Financial Group Inc | 361,161 | $4,759 萬 | 0.03% | – | – |
| Perceptive Advisors LLC | 353,523 | $4,659 萬 | 0.62% | – | – |
| Eaton Vance Management | 353,327 | $4,656 萬 | 0.07% | – | – |
| Dimensional Fund Advisors LP | 342,493 | $4,520 萬 | 0.01% | – | – |
| Durable Capital Partners LP | 320,456 | $4,223 萬 | 0.36% | – | – |
| California Public Employees Retirement System | 317,707 | $4,187 萬 | 0.03% | – | – |
| Wells Fargo & Company | 317,435 | $4,183 萬 | 0.01% | – | – |
| Neuberger Berman Group LLC | 310,810 | $4,092 萬 | 0.04% | – | – |
| ArrowMark Colorado Holdings LLC | 309,160 | $4,074 萬 | 0.30% | – | – |
| Peregrine Capital Management LLC | 303,935 | $4,005 萬 | 0.74% | – | – |
| Banque Pictet & Cie SA | 303,889 | $4,005 萬 | 0.51% | – | – |
| Millennium Management LLC | 286,281 | $3,773 萬 | 0.05% | – | – |
| California State Teachers Retirement System | 281,332 | $3,707 萬 | 0.05% | – | – |
| Fiera Capital Corp | 279,884 | $3,688 萬 | 0.11% | – | – |
| UBS Group AG | 269,833 | $3,556 萬 | 0.02% | – | – |
| TD Asset Management Inc | 259,461 | $3,419 萬 | 0.04% | – | – |
| Kames Capital plc | 258,533 | $3,407 萬 | 0.51% | – | – |
| Balyasny Asset Management LLC | 257,195 | $3,389 萬 | 0.20% | – | – |
| C WorldWide Group Holding A/S | 256,864 | $3,385 萬 | 0.33% | – | – |
| APG Asset Management N.V. | 296,251 | $3,322 萬 | 0.06% | – | – |
| Wasatch Advisors Inc | 249,838 | $3,292 萬 | 0.15% | – | – |
| Cota Capital Management, LLC | 247,854 | $3,266 萬 | 7.18% | – | – |
| Susquehanna International Group, LLP | 240,865 | $3,174 萬 | 0.04% | – | – |
| National Pension Service | 233,385 | $3,076 萬 | 0.06% | – | – |
| Handelsbanken Fonder AB | 228,995 | $3,018 萬 | 0.17% | – | – |
| AXA S.A. | 227,477 | $2,998 萬 | 0.09% | – | – |
| Canada Pension Plan Investment Board | 222,280 | $2,929 萬 | 0.04% | – | – |
| Jennison Associates LLC | 222,094 | $2,927 萬 | 0.02% | – | – |
| Envestnet Asset Management Inc | 219,988 | $2,899 萬 | 0.02% | – | – |
| CIBC Private Wealth Group, LLC | 218,838 | $2,884 萬 | 0.07% | – | – |
| Bellevue Group AG | 218,140 | $2,875 萬 | 0.30% | – | – |
| Lombard Odier Asset Management (Switzerland) SA | 214,610 | $2,828 萬 | 1.89% | – | – |
| Russell Investments Group, Ltd. | 211,290 | $2,770 萬 | 0.05% | – | – |
| Westpac Banking Corp | 199,870 | $2,634 萬 | 0.29% | – | – |
| EULAV Asset Management | 198,000 | $2,609 萬 | 0.70% | – | – |
| Fred Alger Management, LLC | 193,096 | $2,545 萬 | 0.07% | – | – |
| State Board of Administration of Florida Retirement System | 193,039 | $2,544 萬 | 0.05% | – | – |
| Baird Financial Group, Inc. | 190,814 | $2,515 萬 | 0.07% | – | – |
| Citigroup Inc | 180,568 | $2,380 萬 | 0.02% | – | – |
| Parametric Portfolio Associates LLC | 177,088 | $2,334 萬 | 0.01% | – | – |
| Rhenman & Partners Asset Management AB | 175,000 | $2,306 萬 | 1.61% | – | – |
| Advisor Group Holdings, Inc. | 171,873 | $2,265 萬 | 0.05% | – | – |
| Mitsubishi UFJ Trust & Banking Corp | 170,637 | $2,249 萬 | 0.05% | – | – |
| State Farm Mutual Automobile Insurance Co | 170,500 | $2,247 萬 | 0.02% | – | – |
| Candriam Luxembourg S.C.A. | 175,874 | $2,238 萬 | 0.19% | – | – |
| Van Eck Associates Corp | 169,096 | $2,228 萬 | 0.06% | – | – |
