| Viking Global Investors LP大師維京全球投資 | 29,993,708 | $12.1 億 | 3.60% | – | – |
| Matrix Capital Management Company, LP | 12,309,090 | $4.96 億 | 5.72% | – | – |
| Vanguard Group Inc | 10,021,989 | $4.03 億 | 0.01% | – | – |
| Price T Rowe Associates Inc | 9,624,225 | $3.87 億 | 0.04% | – | – |
| BlackRock Inc. | 4,903,045 | $1.97 億 | 0.01% | – | – |
| ARK Investment Management LLC大師方舟投資 | 3,473,910 | $1.40 億 | 0.28% | – | – |
| Gilder Gagnon Howe & Co LLC | 2,384,205 | $9,599 萬 | 0.52% | – | – |
| Massachusetts Financial Services Co | 2,253,948 | $9,074 萬 | 0.03% | – | – |
| Neuberger Berman Group LLC | 2,102,745 | $8,464 萬 | 0.08% | – | – |
| Capital International Investors | 1,832,804 | $7,379 萬 | 0.02% | – | – |
| JPMorgan Chase & Co | 1,388,633 | $5,591 萬 | 0.01% | – | – |
| Invesco Ltd. | 1,319,467 | $5,312 萬 | 0.01% | – | – |
| Casdin Capital, LLC | 1,150,000 | $4,630 萬 | 1.38% | – | – |
| Goldman Sachs Group Inc | 1,131,599 | $4,556 萬 | 0.01% | – | – |
| TimesSquare Capital Management, LLC | 1,115,885 | $4,493 萬 | 0.38% | – | – |
| Tiger Management L.L.C. | 1,115,411 | $4,491 萬 | 8.91% | – | – |
| Geode Capital Management, LLC | 1,082,719 | $4,359 萬 | 0.01% | – | – |
| Zevenbergen Capital Investments LLC | 1,024,583 | $4,125 萬 | 0.78% | – | – |
| Senator Investment Group LP | 1,000,000 | $4,026 萬 | 0.83% | – | – |
| State Street Corp | 953,543 | $3,839 萬 | 0.00% | – | – |
| Lazard Asset Management LLC | 936,014 | $3,768 萬 | 0.05% | – | – |
| Bank of New York Mellon Corp | 871,575 | $3,509 萬 | 0.01% | – | – |
| Ameriprise Financial Inc | 853,032 | $3,434 萬 | 0.01% | – | – |
| Wells Fargo & Company | 816,458 | $3,287 萬 | 0.01% | – | – |
| Rockefeller Capital Management L.P. | 679,563 | $2,736 萬 | 0.19% | – | – |
| Norges Bank | 669,842 | $2,697 萬 | 0.01% | – | – |
| Rock Springs Capital Management LP | 650,000 | $2,617 萬 | 0.57% | – | – |
| Kornitzer Capital Management Inc | 629,100 | $2,533 萬 | 0.41% | – | – |
| Charles Schwab Investment Management Inc | 603,307 | $2,429 萬 | 0.01% | – | – |
| Morgan Stanley | 596,792 | $2,403 萬 | 0.00% | – | – |
| Aristotle Atlantic Partners, LLC | 570,942 | $2,299 萬 | 1.68% | – | – |
| Bamco Inc | 515,158 | $2,074 萬 | 0.05% | – | – |
| Thrivent Financial for Lutherans | 438,125 | $1,764 萬 | 0.04% | – | – |
| Sumitomo Mitsui Trust Holdings, Inc. | 429,103 | $1,728 萬 | 0.01% | – | – |
| Pictet Asset Management Ltd | 421,913 | $1,699 萬 | 0.02% | – | – |
| Northern Trust Corp | 419,470 | $1,689 萬 | 0.00% | – | – |
| Nikko Asset Management Americas, Inc. | 398,810 | $1,606 萬 | 0.08% | – | – |
| Nuveen Asset Management, LLC | 377,094 | $1,518 萬 | 0.00% | – | – |
| Citadel Advisors LLC | 357,793 | $1,441 萬 | 0.02% | – | – |
| Perceptive Advisors LLC | 352,804 | $1,420 萬 | 0.19% | – | – |
| Principal Financial Group Inc | 352,329 | $1,418 萬 | 0.01% | – | – |
| FMR LLC | 345,123 | $1,390 萬 | 0.00% | – | – |
| Tekla Capital Management LLC | 337,722 | $1,360 萬 | 0.47% | – | – |
| Great Lakes Advisors, LLC | 333,152 | $1,341 萬 | 0.22% | – | – |
| First Trust Advisors LP | 326,635 | $1,315 萬 | 0.02% | – | – |
| Berylson Capital Partners, LLC | 316,000 | $1,272 萬 | 3.10% | – | – |
| Chilton Investment Co LLC | 290,027 | $1,168 萬 | 0.32% | – | – |
| Asymmetry Capital Management, L.P. | 287,490 | $1,157 萬 | 5.99% | – | – |
| Blair William & Co | 287,183 | $1,156 萬 | 0.04% | – | – |
| Peregrine Capital Management LLC | 284,293 | $1,145 萬 | 0.21% | – | – |
| UBS Asset Management Americas Inc | 279,121 | $1,124 萬 | 0.00% | – | – |
| Pura Vida Investments, LLC | 256,694 | $1,034 萬 | 0.72% | – | – |
| Bank Julius Baer & Co. Ltd, Zurich | 254,567 | $1,025 萬 | 0.08% | – | – |
| Blue Water Life Science Advisors, LLC | 251,695 | $1,013 萬 | 4.95% | – | – |
| Frontier Capital Management Co LLC | 236,587 | $952.5 萬 | 0.07% | – | – |
| Primecap Management Co | 210,500 | $847.5 萬 | 0.01% | – | – |
| Two Sigma Investments, LP | 203,685 | $820.0 萬 | 0.02% | – | – |
| Swiss National Bank | 203,100 | $817.7 萬 | 0.01% | – | – |
| Eagle Health Investments LP | 202,220 | $814.1 萬 | 3.30% | – | – |
| Robertson Stephens Wealth Management, LLC | 186,536 | $750.9 萬 | 1.20% | – | – |
| Ergoteles LLC | 179,680 | $723.4 萬 | 0.23% | – | – |
| Marshall Wace, LLP | 170,442 | $686.2 萬 | 0.04% | – | – |
| California Public Employees Retirement System | 169,627 | $682.9 萬 | 0.01% | – | – |
| Deutsche Bank AG | 164,800 | $663.5 萬 | 0.00% | – | – |
| Renaissance Technologies LLC | 160,200 | $645.0 萬 | 0.01% | – | – |
| HN Saltoro Capital, LP | 159,100 | $640.5 萬 | 5.27% | – | – |
| Pier Capital, LLC | 156,961 | $631.9 萬 | 0.60% | – | – |
| Bank of America Corp | 144,971 | $583.6 萬 | 0.00% | – | – |
| Man Group plc | 144,735 | $582.7 萬 | 0.03% | – | – |
| California State Teachers Retirement System | 136,554 | $549.8 萬 | 0.01% | – | – |
| Zweig-DiMenna Associates LLC | 135,770 | $546.6 萬 | 0.39% | – | – |
| Dimensional Fund Advisors LP | 134,492 | $541.4 萬 | 0.00% | – | – |
| Voloridge Investment Management, LLC | 133,794 | $538.7 萬 | 0.04% | – | – |
| New York State Common Retirement Fund | 128,744 | $518.3 萬 | 0.01% | – | – |
| Summit Partners Public Asset Management, LLC | 115,072 | $463.3 萬 | 0.25% | – | – |
| DDD Partners, LLC | 109,500 | $440.8 萬 | 0.75% | – | – |
| Renaissance Capital LLC | 107,425 | $432.5 萬 | 0.64% | – | – |
| Marsico Capital Management LLC | 106,723 | $429.7 萬 | 0.11% | – | – |
| CWM, LLC | 103,941 | $424.7 萬 | 0.03% | – | – |
| TD Asset Management Inc | 100,375 | $404.1 萬 | 0.00% | – | – |
| PDT Partners, LLC | 94,516 | $380.5 萬 | 0.27% | – | – |
| SEI Investments Co | 84,675 | $379.7 萬 | 0.01% | – | – |
| Segall Bryant & Hamill, LLC | 93,094 | $374.8 萬 | 0.04% | – | – |
| Edge Wealth Management LLC | 90,000 | $362.3 萬 | 0.77% | – | – |
| State Board of Administration of Florida Retirement System | 85,231 | $343.1 萬 | 0.01% | – | – |
| Parametric Portfolio Associates LLC | 84,459 | $340.0 萬 | 0.00% | – | – |
| Cubist Systematic Strategies, LLC | 83,764 | $337.2 萬 | 0.04% | – | – |
| Ensign Peak Advisors, Inc | 82,743 | $333.1 萬 | 0.01% | – | – |
| Credit Suisse AG | 79,663 | $320.7 萬 | 0.00% | – | – |
| Rhumbline Advisers | 76,682 | $308.7 萬 | 0.00% | – | – |
| Guggenheim Capital LLC | 73,056 | $294.1 萬 | 0.02% | – | – |
| Barclays PLC | 69,090 | $278.2 萬 | 0.00% | – | – |
| Natixis | 68,074 | $274.1 萬 | 0.01% | – | – |
| HRT Financial LP | 67,955 | $273.5 萬 | 0.03% | – | – |
| Susquehanna International Group, LLP | 62,989 | $253.6 萬 | 0.00% | – | – |
| Bradley Foster & Sargent Inc | 61,394 | $247.2 萬 | 0.06% | – | – |
| Allianz Asset Management GmbH | 60,247 | $242.5 萬 | 0.00% | – | – |
| Partners Capital Investment Group, LLP | 59,807 | $240.8 萬 | 0.11% | – | – |
| Crewe Advisors LLC | 59,138 | $238.1 萬 | 0.59% | – | – |
| Duality Advisers, LP | 58,064 | $233.8 萬 | 0.20% | – | – |
