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Zenas BioPharma, Inc.

ZBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001953926

No open-market purchases or sales by Zenas BioPharma, Inc. insiders were filed in the last 90 days; 144 institutions reported holding it in 13F filings for Q2 2026, worth $1.55B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Zenas BioPharma, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
119
+39 vs. Q3 2025
Shares held
42.8M
+8.00M (+23.0%) vs. Q3 2025
Total value
$1.55B
+$776.2M (+100.2%) vs. Q3 2025
New holders
47
37 more added
Sold out
8
24 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 119 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 44 institutionsQ4 2024: 65 institutionsQ1 2025: 67 institutionsQ2 2025: 73 institutionsQ3 2025: 80 institutionsQ4 2025: 119 institutionsQ1 2026: 140 institutionsQ2 2026: 144 institutions
Value heldQ4 2025: $1.55B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $418.5MQ4 2024: $259.6MQ1 2025: $256.7MQ2 2025: $330.0MQ3 2025: $774.5MQ4 2025: $1.55BQ1 2026: $1.14BQ2 2026: $1.55B
Institutions holding ZBIO and their total value by quarter
QuarterHoldersValue
Q2 2026144$1.55B
Q1 2026140$1.14B
Q4 2025119$1.55B
Q3 202580$774.5M
Q2 202573$330.0M
Q1 202567$256.7M
Q4 202465$259.6M
Q3 202444$418.5M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Zenas BioPharma, Inc.; share changes are against Q3 2025.

Institutions holding ZBIO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC7,704,255$279.7M0.01%+2,883,885+59.8%Added
Sr One Capital Management, LP5,037,854$182.9M25.90%+126,315+2.6%Added
Enavate Sciences GP, LLC3,919,159$142.3M28.08%+157,800+4.2%Added
NEA Management Company, LLC3,523,219$127.9M6.52%+789,500+28.9%Added
Federated Hermes, Inc.2,715,578$98.6M0.16%+853,740+45.9%Added
Fairmount Funds Management LLC2,209,025$80.2M6.11%+316,219+16.7%Added
NVP Associates, LLC1,838,482$66.8M26.16%00.0%Unchanged
BlackRock, Inc.1,767,518$64.2M0.00%+538,877+43.9%Added
Vanguard Group Inc1,453,065$52.8M0.00%+290,307+25.0%Added
Novo Holdings A/S1,450,000$52.6M4.09%−550,000−27.5%Reduced
Royalty Pharma Sub-Manager, LLC1,263,150$45.9M26.77%+1,263,150New
Polar Capital Holdings Plc1,057,609$38.4M0.18%+1,057,609New
Wellington Management Group LLP855,334$31.1M0.01%−2,190−0.3%Reduced
Vivo Capital, LLC853,495$31.0M2.00%−329,765−27.9%Reduced
EcoR1 Capital, LLC789,500$28.7M1.31%+789,500New
ArrowMark Colorado Holdings LLC751,161$27.3M0.60%−73,507−8.9%Reduced
Pivotal bioVenture Partners Investment Advisor LLC591,991$21.5M8.31%−187,054−24.0%Reduced
Geode Capital Management, LLC588,393$21.4M0.00%+118,358+25.2%Added
Rock Springs Capital Management LP502,077$18.2M0.94%−78,600−13.5%Reduced
State Street Corp438,294$15.9M0.00%+60,809+16.1%Added
Price T Rowe Associates Inc369,248$13.4M0.00%−5,050−1.3%Reduced
NEXTBio Capital Management LP321,983$11.7M6.86%+321,983New
Point72 Asset Management, L.P.368,400$9.21M0.01%+368,400New
Charles Schwab Investment Management Inc213,193$7.74M0.00%+34,797+19.5%Added
Balyasny Asset Management LLC193,153$7.01M0.01%+193,153New
Invesco Ltd.187,968$6.83M0.00%+42,172+28.9%Added
Skandinaviska Enskilda Banken AB (publ)163,860$5.95M0.02%+163,860New
Northern Trust Corp155,366$5.64M0.00%+22,088+16.6%Added
Voloridge Investment Management, LLC133,439$4.85M0.02%+133,439New
Goldman Sachs Group Inc130,698$4.75M0.00%+130,698New
Morgan Stanley128,335$4.66M0.00%+39,602+44.6%Added
Eversept Partners, LP121,016$4.39M0.25%−37,726−23.8%Reduced
Superstring Capital Management LP83,353$3.03M1.62%−13,312−13.8%Reduced
AQR Capital Management LLC78,220$2.84M0.00%+53,636+218.2%Added
UBS Group AG69,495$2.52M0.00%+34,003+95.8%Added
Bank of New York Mellon Corp51,802$1.88M0.00%+10,114+24.3%Added
Schroder Investment Management Group50,636$1.85M0.00%−61,976−55.0%Reduced
Nuveen, LLC50,850$1.85M0.00%+30,331+147.8%Added
Millennium Management LLC49,160$1.78M0.00%−22,690−31.6%Reduced
Bank of America Corp47,160$1.71M0.00%+32,351+218.5%Added
Alps Advisors Inc44,077$1.60M0.01%+24,035+119.9%Added
Barclays PLC34,377$1.25M0.00%+11,501+50.3%Added
Swiss National Bank31,600$1.15M0.00%+31,600New
Citadel Advisors LLC24,459$888.1K0.00%+24,459New
Rhumbline Advisers21,946$796.9K0.00%+732+3.5%Added
JPMorgan Chase & Co21,726$788.9K0.00%+15,178+231.8%Added
Wells Fargo & Company21,151$768.0K0.00%+8,696+69.8%Added
Alliancebernstein L.P.18,350$666.3K0.00%00.0%Unchanged
California State Teachers Retirement System15,701$570.1K0.00%+14,556+1,271.3%Added
Squarepoint Ops LLC15,541$564.3K0.00%+15,541New
Two Sigma Investments, LP15,100$548.3K0.00%−5,282−25.9%Reduced
Voya Investment Management LLC14,725$534.7K0.00%+14,725New
Susquehanna International Group, LLP13,678$496.6K0.00%+13,678New
China Universal Asset Management Co., Ltd.13,314$483.4K0.04%+13,314New
Legal & General Group Plc13,027$473.0K0.00%+11,673+862.1%Added
Deutsche Bank AG12,781$464.1K0.00%+554+4.5%Added
Creative Planning12,273$445.6K0.00%+391+3.3%Added
XTX Topco Ltd12,183$442.4K0.01%+12,183New
Los Angeles Capital Management LLC14,447$431.7K0.00%+14,447New
State of Wisconsin Investment Board10,221$371.1K0.00%+10,221New
Voleon Capital Management LP10,187$369.9K0.01%+10,187New
MetLife Investment Management10,100$366.7K0.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC9,127$331.4K0.00%+9,127New
Gsa Capital Partners LLP8,956$325.0K0.03%+8,956New
Intech Investment Management LLC8,863$321.8K0.00%+8,863New
Mirae Asset Global ETFs Holdings Ltd.8,780$318.8K0.00%+1,319+17.7%Added
UBS Asset Management Americas Inc8,400$305.0K0.00%+8,400New
Janus Henderson Group PLC7,900$286.6K0.00%+7,900New
Mariner, LLC7,676$278.7K0.00%+7,676New
VARCOV Co.7,335$266.3K0.11%+7,335New
BNP Paribas Arbitrage, SA7,138$259.2K0.00%+3,992+126.9%Added
Marshall Wace, LLP7,100$257.8K0.00%+7,100New
Virtus Investment Advisers, Inc.6,554$238.0K0.06%+6,554New
Manufacturers Life Insurance Company, The6,256$227.2K0.00%+6,256New
New York State Common Retirement Fund6,200$225.1K0.00%00.0%Unchanged
Brevan Howard Capital Management LP6,173$224.1K0.00%+6,173New
The PNC Financial Services Group, Inc.5,824$211.5K0.00%−19−0.3%Reduced
ProShare Advisors LLC5,820$211.3K0.00%+5,820New
Police & Firemen's Retirement System of New Jersey4,499$163.4K0.00%00.0%Unchanged
KLP Kapitalforvaltning AS3,400$123.5K0.00%+3,400New
STRS Ohio2,800$101.7K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,608$94.7K0.00%+2,608New
Citigroup Inc2,351$85.4K0.00%+2,163+1,150.5%Added
CWM, LLC2,178$79.0K0.00%+709+48.3%Added
Simplex Trading, LLC1,974$71.7K0.00%+1,974New
Ameritas Investment Partners, Inc.1,368$49.7K0.00%−240−14.9%Reduced
Russell Investments Group, Ltd.1,345$48.8K0.00%00.0%Unchanged
Sterling Capital Management LLC1,087$39.5K0.00%−34−3.0%Reduced
GF Fund Management Co. Ltd.1,054$38.3K0.00%+1,054New
US Bancorp884$32.1K0.00%−69−7.2%Reduced
Tower Research Capital LLC (TRC)795$28.9K0.00%−593−42.7%Reduced
Amalgamated Bank593$22.0K0.00%+69+13.2%Added
Royal Bank of Canada544$20.0K0.00%−11,337−95.4%Reduced
Signaturefd, LLC389$14.1K0.00%+57+17.2%Added
GAMMA Investing LLC179$6.50K0.00%−4−2.2%Reduced
Daiwa Securities Group Inc.179$6.00K0.00%+179New
Nisa Investment Advisors, LLC115$4.18K0.00%00.0%Unchanged
Torren Management, LLC95$3.45K0.00%+95New
J.Safra Asset Management Corp92$3.34K0.00%+92New
Farther Finance Advisors, LLC86$3.12K0.00%+62+258.3%Added