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Xencor Inc

XNCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001326732

No open-market purchases or sales by Xencor Inc insiders were filed in the last 90 days; 208 institutions reported holding it in 13F filings for Q2 2026, worth $1.36B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Xencor Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
208
+7 vs. Q3 2025
Shares held
81.9M
+45.8K (+0.1%) vs. Q3 2025
Total value
$1.25B
+$294.5M (+30.7%) vs. Q3 2025
New holders
35
60 more added
Sold out
28
78 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XNCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 208 institutions
Q1 2021: 170 institutionsQ2 2021: 178 institutionsQ3 2021: 170 institutionsQ4 2021: 178 institutionsQ1 2022: 181 institutionsQ2 2022: 176 institutionsQ3 2022: 186 institutionsQ4 2022: 197 institutionsQ1 2023: 188 institutionsQ2 2023: 182 institutionsQ3 2023: 178 institutionsQ4 2023: 195 institutionsQ1 2024: 201 institutionsQ2 2024: 198 institutionsQ3 2024: 210 institutionsQ4 2024: 192 institutionsQ1 2025: 202 institutionsQ2 2025: 194 institutionsQ3 2025: 206 institutionsQ4 2025: 208 institutionsQ1 2026: 203 institutionsQ2 2026: 208 institutions
Value heldQ4 2025: $1.25B
Q1 2021: $2.52BQ2 2021: $2.00BQ3 2021: $1.90BQ4 2021: $2.37BQ1 2022: $1.58BQ2 2022: $1.64BQ3 2022: $1.58BQ4 2022: $1.60BQ1 2023: $1.77BQ2 2023: $1.57BQ3 2023: $1.27BQ4 2023: $1.35BQ1 2024: $1.44BQ2 2024: $1.20BQ3 2024: $1.45BQ4 2024: $1.72BQ1 2025: $837.9MQ2 2025: $646.9MQ3 2025: $960.2MQ4 2025: $1.25BQ1 2026: $1.02BQ2 2026: $1.36B
Institutions holding XNCR and their total value by quarter
QuarterHoldersValue
Q2 2026208$1.36B
Q1 2026203$1.02B
Q4 2025208$1.25B
Q3 2025206$960.2M
Q2 2025194$646.9M
Q1 2025202$837.9M
Q4 2024192$1.72B
Q3 2024210$1.45B
Q2 2024198$1.20B
Q1 2024201$1.44B
Q4 2023195$1.35B
Q3 2023178$1.27B
Q2 2023182$1.57B
Q1 2023188$1.77B
Q4 2022197$1.60B
Q3 2022186$1.58B
Q2 2022176$1.64B
Q1 2022181$1.58B
Q4 2021178$2.37B
Q3 2021170$1.90B
Q2 2021178$2.00B
Q1 2021170$2.52B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Xencor Inc; share changes are against Q3 2025.

Institutions holding XNCR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
TCG Crossover Management, LLC2,452,138$37.5M1.24%00.0%Unchanged
EcoR1 Capital, LLC3,251,112$49.8M2.28%−2,893,655−47.1%Reduced
State Street Corp4,507,254$69.0M0.00%+833,423+22.7%Added
RTW Investments, LP6,777,461$103.8M1.04%+556,407+8.9%Added
BVF Inc7,133,720$109.2M3.68%+4,393,579+160.3%Added
Vanguard Group Inc7,165,450$109.7M0.00%+61,692+0.9%Added
Primecap Management Co10,218,322$156.4M0.12%−456,700−4.3%Reduced
BlackRock, Inc.11,927,218$182.6M0.00%+119,991+1.0%Added
Standard Life Aberdeen plc0$00.00%−558,810−100.0%Sold out
Deep Track Capital, LP0$00.00%−549,439−100.0%Sold out
Macquarie Group Ltd0$00.00%−400,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−216,739−100.0%Sold out
HRT Financial LP0$00.00%−124,063−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−123,138−100.0%Sold out
Weiss Asset Management LP0$00.00%−66,273−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−64,184−100.0%Sold out
Marshall Wace, LLP0$00.00%−41,716−100.0%Sold out
Jain Global LLC0$00.00%−34,781−100.0%Sold out
Atom Investors LP0$00.00%−32,362−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−24,438−100.0%Sold out
Verition Fund Management LLC0$00.00%−21,425−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−14,826−100.0%Sold out
Quantessence Capital LLC0$00.00%−13,094−100.0%Sold out
Inceptionr LLC0$00.00%−13,007−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−12,627−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−11,880−100.0%Sold out
Amundi0$00.00%−11,408−100.0%Sold out
ISAM Funds (UK) Ltd0$00.00%−7,838−100.0%Sold out
Natixis0$00.00%−1,912−100.0%Sold out
Optiver Holding B.V.0$00.00%−320−100.0%Sold out
Atlantic Trust, LLC0$00.00%−51−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−31−100.0%Sold out
Advisory Services Network, LLC0$00.00%−21−100.0%Sold out
Bell Investment Advisors, Inc0$00.00%−19−100.0%Sold out
Larson Financial Group LLC0$00.00%−1−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−1−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Corton Capital Inc.––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Shell Asset Management Co––––Not filed
Point72 (DIFC) Ltd––––Not filed