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Xencor Inc

XNCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001326732

No open-market purchases or sales by Xencor Inc insiders were filed in the last 90 days; 208 institutions reported holding it in 13F filings for Q2 2026, worth $1.36B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Xencor Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
206
+15 vs. Q2 2025
Shares held
81.9M
−284.4K (−0.3%) vs. Q2 2025
Total value
$960.2M
+$313.7M (+48.5%) vs. Q2 2025
New holders
33
57 more added
Sold out
18
81 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XNCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 206 institutions
Q1 2021: 170 institutionsQ2 2021: 178 institutionsQ3 2021: 170 institutionsQ4 2021: 178 institutionsQ1 2022: 181 institutionsQ2 2022: 176 institutionsQ3 2022: 186 institutionsQ4 2022: 197 institutionsQ1 2023: 188 institutionsQ2 2023: 182 institutionsQ3 2023: 178 institutionsQ4 2023: 195 institutionsQ1 2024: 201 institutionsQ2 2024: 198 institutionsQ3 2024: 210 institutionsQ4 2024: 192 institutionsQ1 2025: 202 institutionsQ2 2025: 194 institutionsQ3 2025: 206 institutionsQ4 2025: 208 institutionsQ1 2026: 203 institutionsQ2 2026: 208 institutions
Value heldQ3 2025: $960.2M
Q1 2021: $2.52BQ2 2021: $2.00BQ3 2021: $1.90BQ4 2021: $2.37BQ1 2022: $1.58BQ2 2022: $1.64BQ3 2022: $1.58BQ4 2022: $1.60BQ1 2023: $1.77BQ2 2023: $1.57BQ3 2023: $1.27BQ4 2023: $1.35BQ1 2024: $1.44BQ2 2024: $1.20BQ3 2024: $1.45BQ4 2024: $1.72BQ1 2025: $837.9MQ2 2025: $646.9MQ3 2025: $960.2MQ4 2025: $1.25BQ1 2026: $1.02BQ2 2026: $1.36B
Institutions holding XNCR and their total value by quarter
QuarterHoldersValue
Q2 2026208$1.36B
Q1 2026203$1.02B
Q4 2025208$1.25B
Q3 2025206$960.2M
Q2 2025194$646.9M
Q1 2025202$837.9M
Q4 2024192$1.72B
Q3 2024210$1.45B
Q2 2024198$1.20B
Q1 2024201$1.44B
Q4 2023195$1.35B
Q3 2023178$1.27B
Q2 2023182$1.57B
Q1 2023188$1.77B
Q4 2022197$1.60B
Q3 2022186$1.58B
Q2 2022176$1.64B
Q1 2022181$1.58B
Q4 2021178$2.37B
Q3 2021170$1.90B
Q2 2021178$2.00B
Q1 2021170$2.52B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Xencor Inc; share changes are against Q2 2025.

Institutions holding XNCR in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.11,807,227$138.5M0.00%−48,027−0.4%Reduced
Primecap Management Co10,675,022$125.2M0.10%+147,700+1.4%Added
Vanguard Group Inc7,103,758$83.3M0.00%−1,520,616−17.6%Reduced
RTW Investments, LP6,221,054$73.0M0.90%+3,818,171+158.9%Added
EcoR1 Capital, LLC6,144,767$72.1M3.47%00.0%Unchanged
State Street Corp3,673,831$43.1M0.00%−143,779−3.8%Reduced
BVF Inc2,740,141$32.1M1.30%00.0%Unchanged
TCG Crossover Management, LLC2,452,138$28.8M1.41%00.0%Unchanged
Geode Capital Management, LLC1,728,825$20.3M0.00%+25,161+1.5%Added
Price T Rowe Associates Inc1,693,292$19.9M0.00%−2,066,892−55.0%Reduced
Dimensional Fund Advisors LP1,588,963$18.6M0.00%−191,607−10.8%Reduced
Legal & General Group Plc1,273,000$14.9M0.00%+1,092,095+603.7%Added
Braidwell LP1,246,280$14.6M0.43%−409,410−24.7%Reduced
UBS Group AG1,175,267$13.8M0.00%+399,071+51.4%Added
Baker Bros. Advisors LP1,102,106$12.9M0.09%+431,675+64.4%Added
Nantahala Capital Management, LLC1,100,000$12.9M0.80%+279,897+34.1%Added
Goldman Sachs Group Inc1,017,453$11.9M0.00%+301,061+42.0%Added
Morgan Stanley900,837$10.6M0.00%−124,561−12.1%Reduced
Two Sigma Advisers, LP810,200$9.50M0.02%+230,900+39.9%Added
Bank of America Corp753,829$8.84M0.00%−185,164−19.7%Reduced
Johnson & Johnson748,062$8.77M1.74%00.0%Unchanged
Northern Trust Corp712,201$8.35M0.00%−3,666−0.5%Reduced
Millennium Management LLC702,574$8.24M0.01%+355,640+102.5%Added
Charles Schwab Investment Management Inc688,269$8.07M0.00%+89,230+14.9%Added
Two Sigma Investments, LP629,376$7.38M0.01%+189,533+43.1%Added
Panagora Asset Management Inc621,029$7.28M0.03%+132,137+27.0%Added
Barclays PLC600,345$7.04M0.00%−54,052−8.3%Reduced
Standard Life Aberdeen plc558,810$6.55M0.01%00.0%Unchanged
Deep Track Capital, LP549,439$6.44M0.18%00.0%Unchanged
Acadian Asset Management LLC532,202$6.24M0.01%+439,588+474.6%Added
Citadel Advisors LLC481,168$5.64M0.00%+260,900+118.4%Added
Hudson Bay Capital Management LP460,003$5.40M0.03%−24,997−5.2%Reduced
Bank of New York Mellon Corp425,788$4.99M0.00%−52,890−11.0%Reduced
JPMorgan Chase & Co401,501$4.71M0.00%+71,494+21.7%Added
Erste Asset Management GmbH380,200$4.39M0.04%00.0%Unchanged
Algert Global LLC360,462$4.23M0.07%+228,417+173.0%Added
Royal Bank of Canada346,226$4.06M0.00%−972,808−73.8%Reduced
Principal Financial Group Inc344,456$4.04M0.00%−8,383−2.4%Reduced
Macquarie Group Ltd400,000$3.92M0.00%+200,000+100.0%Added
Public Sector Pension Investment Board278,227$3.26M0.01%+35,575+14.7%Added
Invesco Ltd.251,604$2.95M0.00%+34,703+16.0%Added
Squarepoint Ops LLC216,739$2.54M0.01%−146,414−40.3%Reduced
Woodline Partners LP193,117$2.27M0.01%−650,179−77.1%Reduced
Renaissance Technologies LLC190,389$2.23M0.00%+134,789+242.4%Added
DCF Advisers, LLC189,736$2.23M0.84%+49,736+35.5%Added
Rhumbline Advisers175,849$2.06M0.00%−555−0.3%Reduced
Jump Financial, LLC175,741$2.06M0.03%+48,769+38.4%Added
American Century Companies Inc173,382$2.03M0.00%+17,409+11.2%Added
UBS Asset Management Americas Inc166,142$1.95M0.00%−43,233−20.6%Reduced
Rhenman & Partners Asset Management AB165,750$1.94M0.22%00.0%Unchanged
Ameriprise Financial Inc146,683$1.72M0.00%−168,170−53.4%Reduced
Trexquant Investment LP136,110$1.60M0.02%−35,310−20.6%Reduced
Nuveen, LLC134,051$1.57M0.00%00.0%Unchanged
ADAR1 Capital Management, LLC128,865$1.51M0.15%+43,039+50.1%Added
Winton Group Ltd125,455$1.47M0.06%+34,214+37.5%Added
BNP Paribas Arbitrage, SA124,124$1.46M0.00%+5,154+4.3%Added
HRT Financial LP124,063$1.46M0.01%+124,063New
Y-Intercept (Hong Kong) Ltd123,138$1.44M0.03%+27,393+28.6%Added
Swiss National Bank115,300$1.35M0.00%00.0%Unchanged
Susquehanna Portfolio Strategies, LLC106,855$1.25M0.02%+106,855New
Jefferies Financial Group Inc.100,000$1.17M0.01%+100,000New
Cubist Systematic Strategies, LLC99,902$1.17M0.02%−235,591−70.2%Reduced
Essex LLC99,861$1.17M0.21%−6,100−5.8%Reduced
Los Angeles Capital Management LLC98,738$1.16M0.00%+2,891+3.0%Added
Manufacturers Life Insurance Company, The95,107$1.12M0.00%−9,543−9.1%Reduced
SG Americas Securities, LLC90,501$1.06M0.00%+90,501New
Thrivent Financial for Lutherans87,544$1.03M0.00%−33,593−27.7%Reduced
AQR Capital Management LLC86,818$1.02M0.00%−9,483−9.8%Reduced
TD Asset Management Inc85,736$1.01M0.00%−15,986−15.7%Reduced
FMR LLC73,930$867.2K0.00%+5,603+8.2%Added
Alliancebernstein L.P.72,090$845.6K0.00%00.0%Unchanged
Prudential Financial Inc72,035$845.0K0.00%+45+0.1%Added
Rafferty Asset Management, LLC69,876$819.6K0.00%−20,723−22.9%Reduced
Great West Life Assurance Co70,015$808.0K0.00%00.0%Unchanged
Weiss Asset Management LP66,273$777.4K0.01%+66,273New
Susquehanna Fundamental Investments, LLC64,184$752.9K0.03%00.0%Unchanged
New York State Teachers Retirement System59,626$699.0K0.00%+200+0.3%Added
California State Teachers Retirement System58,603$687.4K0.00%+4,410+8.1%Added
Wells Fargo & Company54,740$642.1K0.00%+8,607+18.7%Added
CIBC Private Wealth Group, LLC52,563$616.6K0.00%+35,000+199.3%Added
Toronto Dominion Bank50,000$586.5K0.00%+50,000New
Brevan Howard Capital Management LP49,235$577.5K0.01%+49,235New
Deutsche Bank AG45,233$530.6K0.00%+5,748+14.6%Added
Quantinno Capital Management LP45,102$529.0K0.00%+15,872+54.3%Added
Franklin Resources Inc44,680$524.1K0.00%−30.0%Reduced
Linden Thomas Advisory Services, LLC42,772$501.7K0.05%+267+0.6%Added
Marshall Wace, LLP41,716$489.3K0.00%+41,716New
Man Group plc40,568$475.9K0.00%−21,184−34.3%Reduced
Engineers Gate Manager LP40,201$471.6K0.01%−10,361−20.5%Reduced
CWM Advisors, LLC39,480$463.1K0.05%−9,631−19.6%Reduced
Fox Run Management, L.L.C.36,674$430.2K0.07%+36,674New
Mirae Asset Global ETFs Holdings Ltd.36,650$429.3K0.00%−6,615−15.3%Reduced
State of Alaska, Department of Revenue35,888$420.0K0.00%−6,463−15.3%Reduced
MetLife Investment Management35,090$411.6K0.00%−5,263−13.0%Reduced
Jain Global LLC34,781$408.0K0.01%−4,200−10.8%Reduced
Alps Advisors Inc34,033$399.2K0.00%−4,366−11.4%Reduced
Louisiana State Employees Retirement System32,800$384.7K0.01%−500−1.5%Reduced
Atom Investors LP32,362$379.6K0.03%+32,362New
State of Tennessee, Treasury Department30,993$363.5K0.00%+272+0.9%Added
DekaBank Deutsche Girozentrale31,800$355.0K0.00%00.0%Unchanged