Xencor Inc
XNCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001326732
No open-market purchases or sales by Xencor Inc insiders were filed in the last 90 days; 208 institutions reported holding it in 13F filings for Q2 2026, worth $1.36B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Xencor Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 208
- +7 vs. Q3 2025
- Shares held
- 81.9M
- +45.8K (+0.1%) vs. Q3 2025
- Total value
- $1.25B
- +$294.5M (+30.7%) vs. Q3 2025
- New holders
- 35
- 60 more added
- Sold out
- 28
- 78 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XNCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $1.36B |
| Q1 2026 | 203 | $1.02B |
| Q4 2025 | 208 | $1.25B |
| Q3 2025 | 206 | $960.2M |
| Q2 2025 | 194 | $646.9M |
| Q1 2025 | 202 | $837.9M |
| Q4 2024 | 192 | $1.72B |
| Q3 2024 | 210 | $1.45B |
| Q2 2024 | 198 | $1.20B |
| Q1 2024 | 201 | $1.44B |
| Q4 2023 | 195 | $1.35B |
| Q3 2023 | 178 | $1.27B |
| Q2 2023 | 182 | $1.57B |
| Q1 2023 | 188 | $1.77B |
| Q4 2022 | 197 | $1.60B |
| Q3 2022 | 186 | $1.58B |
| Q2 2022 | 176 | $1.64B |
| Q1 2022 | 181 | $1.58B |
| Q4 2021 | 178 | $2.37B |
| Q3 2021 | 170 | $1.90B |
| Q2 2021 | 178 | $2.00B |
| Q1 2021 | 170 | $2.52B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Xencor Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 11,927,218 | $182.6M | 0.00% | +119,991+1.0% | Added |
| Primecap Management Co | 10,218,322 | $156.4M | 0.12% | −456,700−4.3% | Reduced |
| Vanguard Group Inc | 7,165,450 | $109.7M | 0.00% | +61,692+0.9% | Added |
| BVF Inc | 7,133,720 | $109.2M | 3.68% | +4,393,579+160.3% | Added |
| RTW Investments, LP | 6,777,461 | $103.8M | 1.04% | +556,407+8.9% | Added |
| State Street Corp | 4,507,254 | $69.0M | 0.00% | +833,423+22.7% | Added |
| EcoR1 Capital, LLC | 3,251,112 | $49.8M | 2.28% | −2,893,655−47.1% | Reduced |
| TCG Crossover Management, LLC | 2,452,138 | $37.5M | 1.24% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,752,918 | $26.8M | 0.00% | +24,093+1.4% | Added |
| Price T Rowe Associates Inc | 1,601,762 | $24.5M | 0.00% | −91,530−5.4% | Reduced |
| Morgan Stanley | 1,508,727 | $23.1M | 0.00% | +607,890+67.5% | Added |
| Defilade Capital Management, L.P. | 1,414,755 | $21.7M | 2.94% | +1,414,755 | New |
| Legal & General Group Plc | 1,308,088 | $20.0M | 0.00% | +35,088+2.8% | Added |
| Dimensional Fund Advisors LP | 1,249,288 | $19.1M | 0.00% | −339,675−21.4% | Reduced |
| Baker Bros. Advisors LP | 1,102,106 | $16.9M | 0.10% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 753,258 | $11.5M | 0.00% | −264,195−26.0% | Reduced |
| Johnson & Johnson | 748,062 | $11.5M | 2.06% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 720,440 | $11.0M | 0.09% | +620,440+620.4% | Added |
| Lynx1 Capital Management LP | 705,558 | $10.8M | 2.19% | +705,558 | New |
| Charles Schwab Investment Management Inc | 700,435 | $10.7M | 0.00% | +12,166+1.8% | Added |
| Northern Trust Corp | 674,657 | $10.3M | 0.00% | −37,544−5.3% | Reduced |
| UBS Group AG | 638,021 | $9.77M | 0.00% | −537,246−45.7% | Reduced |
| Bank of America Corp | 629,408 | $9.64M | 0.00% | −124,421−16.5% | Reduced |
| Millennium Management LLC | 594,435 | $9.10M | 0.01% | −108,139−15.4% | Reduced |
| Panagora Asset Management Inc | 583,778 | $8.94M | 0.03% | −37,251−6.0% | Reduced |
| Two Sigma Advisers, LP | 506,600 | $7.76M | 0.02% | −303,600−37.5% | Reduced |
| Toronto Dominion Bank | 491,000 | $7.52M | 0.01% | +441,000+882.0% | Added |
| Erste Asset Management GmbH | 480,200 | $7.35M | 0.06% | +100,000+26.3% | Added |
| Braidwell LP | 459,166 | $7.03M | 0.22% | −787,114−63.2% | Reduced |
| Hudson Bay Capital Management LP | 425,000 | $6.51M | 0.04% | −35,003−7.6% | Reduced |
| Acadian Asset Management LLC | 411,725 | $6.30M | 0.01% | −120,477−22.6% | Reduced |
| Bank of New York Mellon Corp | 410,650 | $6.29M | 0.00% | −15,138−3.6% | Reduced |
| Barclays PLC | 359,235 | $5.50M | 0.00% | −241,110−40.2% | Reduced |
| Principal Financial Group Inc | 340,326 | $5.21M | 0.00% | −4,130−1.2% | Reduced |
| Citadel Advisors LLC | 321,808 | $4.93M | 0.00% | −159,360−33.1% | Reduced |
| JPMorgan Chase & Co | 303,979 | $4.65M | 0.00% | −97,522−24.3% | Reduced |
| Two Sigma Investments, LP | 268,737 | $4.11M | 0.01% | −360,639−57.3% | Reduced |
| Invesco Ltd. | 265,820 | $4.07M | 0.00% | +14,216+5.7% | Added |
| Jacobs Levy Equity Management, Inc | 259,319 | $3.97M | 0.02% | +259,319 | New |
| Public Sector Pension Investment Board | 247,242 | $3.79M | 0.01% | −30,985−11.1% | Reduced |
| Deutsche Bank AG | 216,568 | $3.32M | 0.00% | +171,335+378.8% | Added |
| Nomura Asset Management International Inc. | 200,000 | $3.06M | 0.00% | +200,000 | New |
| Woodline Partners LP | 193,117 | $2.96M | 0.01% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 191,463 | $2.93M | 0.05% | +84,608+79.2% | Added |
| Trexquant Investment LP | 175,152 | $2.68M | 0.02% | +39,042+28.7% | Added |
| American Century Companies Inc | 174,603 | $2.67M | 0.00% | +1,221+0.7% | Added |
| Rhumbline Advisers | 165,797 | $2.54M | 0.00% | −10,052−5.7% | Reduced |
| Rhenman & Partners Asset Management AB | 165,750 | $2.54M | 0.24% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 164,639 | $2.52M | 0.15% | −935,361−85.0% | Reduced |
| DCF Advisers, LLC | 154,736 | $2.37M | 0.78% | −35,000−18.4% | Reduced |
| Ameriprise Financial Inc | 135,806 | $2.08M | 0.00% | −10,877−7.4% | Reduced |
| Nuveen, LLC | 134,051 | $2.05M | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 128,345 | $1.97M | 0.00% | +37,844+41.8% | Added |
| Algert Global LLC | 124,400 | $1.90M | 0.03% | −236,062−65.5% | Reduced |
| UBS Asset Management Americas Inc | 119,789 | $1.83M | 0.00% | −46,353−27.9% | Reduced |
| Swiss National Bank | 119,600 | $1.83M | 0.00% | +4,300+3.7% | Added |
| Citigroup Inc | 112,275 | $1.72M | 0.00% | +88,612+374.5% | Added |
| AQR Capital Management LLC | 112,271 | $1.72M | 0.00% | +25,453+29.3% | Added |
| Seven Fleet Capital Management LP | 109,554 | $1.68M | 1.14% | +109,554 | New |
| Essex LLC | 98,661 | $1.51M | 0.27% | −1,200−1.2% | Reduced |
| Rafferty Asset Management, LLC | 97,749 | $1.50M | 0.01% | +27,873+39.9% | Added |
| FMR LLC | 92,883 | $1.42M | 0.00% | +18,953+25.6% | Added |
| Winton Group Ltd | 88,038 | $1.35M | 0.05% | −37,417−29.8% | Reduced |
| Voloridge Investment Management, LLC | 87,717 | $1.34M | 0.00% | +87,717 | New |
| Thrivent Financial for Lutherans | 82,828 | $1.27M | 0.00% | −4,716−5.4% | Reduced |
| Manufacturers Life Insurance Company, The | 82,942 | $1.25M | 0.00% | −12,165−12.8% | Reduced |
| Wells Fargo & Company | 79,667 | $1.22M | 0.00% | +24,927+45.5% | Added |
| TD Asset Management Inc | 77,802 | $1.19M | 0.00% | −7,934−9.3% | Reduced |
| Alliancebernstein L.P. | 72,090 | $1.10M | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 70,612 | $1.08M | 0.01% | +41,015+138.6% | Added |
| New York State Teachers Retirement System | 70,526 | $1.08M | 0.00% | +10,900+18.3% | Added |
| Prudential Financial Inc | 67,570 | $1.03M | 0.00% | −4,465−6.2% | Reduced |
| NEOS Investment Management LLC | 61,362 | $939.5K | 0.01% | +61,362 | New |
| Tema ETFs LLC | 60,457 | $925.6K | 0.07% | +60,457 | New |
| Alps Advisors Inc | 58,639 | $897.8K | 0.01% | +24,606+72.3% | Added |
| California State Teachers Retirement System | 58,530 | $896.1K | 0.00% | −73−0.1% | Reduced |
| Great West Life Assurance Co | 57,164 | $875.0K | 0.00% | −12,851−18.4% | Reduced |
| ADAR1 Capital Management, LLC | 56,165 | $859.9K | 0.06% | −72,700−56.4% | Reduced |
| Point72 Asset Management, L.P. | 55,339 | $847.2K | 0.00% | +55,339 | New |
| DekaBank Deutsche Girozentrale | 31,800 | $775.0K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 48,687 | $745.4K | 0.00% | −75,437−60.8% | Reduced |
| Schonfeld Strategic Advisors LLC | 47,848 | $732.6K | 0.00% | +35,086+274.9% | Added |
| Russell Investments Group, Ltd. | 47,189 | $722.5K | 0.00% | +35,185+293.1% | Added |
| Quantinno Capital Management LP | 47,134 | $721.6K | 0.00% | +2,032+4.5% | Added |
| Profund Advisors LLC | 43,960 | $673.0K | 0.02% | +26,375+150.0% | Added |
| Franklin Resources Inc | 41,225 | $631.2K | 0.00% | −3,455−7.7% | Reduced |
| Linden Thomas Advisory Services, LLC | 40,963 | $627.1K | 0.06% | −1,809−4.2% | Reduced |
| MetLife Investment Management | 40,212 | $615.6K | 0.00% | +5,122+14.6% | Added |
| CIBC Private Wealth Group, LLC | 40,017 | $612.7K | 0.00% | −12,546−23.9% | Reduced |
| State of Wisconsin Investment Board | 38,825 | $594.4K | 0.00% | +20,274+109.3% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 38,448 | $587.0K | 0.00% | +1,798+4.9% | Added |
| Raymond James Financial Inc | 38,037 | $582.3K | 0.00% | +21,308+127.4% | Added |
| State of Alaska, Department of Revenue | 36,407 | $557.0K | 0.01% | +519+1.4% | Added |
| Tudor Investment Corp Et Al | 34,794 | $532.7K | 0.00% | +34,794 | New |
| Renaissance Technologies LLC | 34,158 | $523.0K | 0.00% | −156,231−82.1% | Reduced |
| Jump Financial, LLC | 33,198 | $508.3K | 0.01% | −142,543−81.1% | Reduced |
| Louisiana State Employees Retirement System | 32,700 | $500.6K | 0.01% | −100−0.3% | Reduced |
| XTX Topco Ltd | 32,009 | $490.1K | 0.01% | +32,009 | New |
| Los Angeles Capital Management LLC | 34,097 | $481.8K | 0.00% | −64,641−65.5% | Reduced |
| Cerity Partners LLC | 31,302 | $479.2K | 0.00% | +1,143+3.8% | Added |