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Xencor Inc

XNCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001326732

No open-market purchases or sales by Xencor Inc insiders were filed in the last 90 days; 208 institutions reported holding it in 13F filings for Q2 2026, worth $1.36B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Xencor Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
208
+7 vs. Q3 2025
Shares held
81.9M
+45.8K (+0.1%) vs. Q3 2025
Total value
$1.25B
+$294.5M (+30.7%) vs. Q3 2025
New holders
35
60 more added
Sold out
28
78 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XNCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 208 institutions
Q1 2021: 170 institutionsQ2 2021: 178 institutionsQ3 2021: 170 institutionsQ4 2021: 178 institutionsQ1 2022: 181 institutionsQ2 2022: 176 institutionsQ3 2022: 186 institutionsQ4 2022: 197 institutionsQ1 2023: 188 institutionsQ2 2023: 182 institutionsQ3 2023: 178 institutionsQ4 2023: 195 institutionsQ1 2024: 201 institutionsQ2 2024: 198 institutionsQ3 2024: 210 institutionsQ4 2024: 192 institutionsQ1 2025: 202 institutionsQ2 2025: 194 institutionsQ3 2025: 206 institutionsQ4 2025: 208 institutionsQ1 2026: 203 institutionsQ2 2026: 208 institutions
Value heldQ4 2025: $1.25B
Q1 2021: $2.52BQ2 2021: $2.00BQ3 2021: $1.90BQ4 2021: $2.37BQ1 2022: $1.58BQ2 2022: $1.64BQ3 2022: $1.58BQ4 2022: $1.60BQ1 2023: $1.77BQ2 2023: $1.57BQ3 2023: $1.27BQ4 2023: $1.35BQ1 2024: $1.44BQ2 2024: $1.20BQ3 2024: $1.45BQ4 2024: $1.72BQ1 2025: $837.9MQ2 2025: $646.9MQ3 2025: $960.2MQ4 2025: $1.25BQ1 2026: $1.02BQ2 2026: $1.36B
Institutions holding XNCR and their total value by quarter
QuarterHoldersValue
Q2 2026208$1.36B
Q1 2026203$1.02B
Q4 2025208$1.25B
Q3 2025206$960.2M
Q2 2025194$646.9M
Q1 2025202$837.9M
Q4 2024192$1.72B
Q3 2024210$1.45B
Q2 2024198$1.20B
Q1 2024201$1.44B
Q4 2023195$1.35B
Q3 2023178$1.27B
Q2 2023182$1.57B
Q1 2023188$1.77B
Q4 2022197$1.60B
Q3 2022186$1.58B
Q2 2022176$1.64B
Q1 2022181$1.58B
Q4 2021178$2.37B
Q3 2021170$1.90B
Q2 2021178$2.00B
Q1 2021170$2.52B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Xencor Inc; share changes are against Q3 2025.

Institutions holding XNCR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Brevan Howard Capital Management LP23,051$352.9K0.01%−26,184−53.2%Reduced
Janus Henderson Group PLC23,986$367.1K0.00%00.0%Unchanged
Palumbo Wealth Management LLC27,090$414.7K0.10%+27,090New
Skopos Labs, Inc.29,142$442.1K0.02%+29,142New
Wellington Management Group LLP29,031$444.5K0.00%+29,031New
Quinn Opportunity Partners LLC30,000$459.3K0.02%00.0%Unchanged
CWM Advisors, LLC30,676$469.7K0.04%−8,804−22.3%Reduced
Susquehanna International Group, LLP30,803$471.6K0.00%+4,348+16.4%Added
Cerity Partners LLC31,302$479.2K0.00%+1,143+3.8%Added
Los Angeles Capital Management LLC34,097$481.8K0.00%−64,641−65.5%Reduced
XTX Topco Ltd32,009$490.1K0.01%+32,009New
Louisiana State Employees Retirement System32,700$500.6K0.01%−100−0.3%Reduced
Jump Financial, LLC33,198$508.3K0.01%−142,543−81.1%Reduced
Renaissance Technologies LLC34,158$523.0K0.00%−156,231−82.1%Reduced
Tudor Investment Corp Et Al34,794$532.7K0.00%+34,794New
State of Alaska, Department of Revenue36,407$557.0K0.01%+519+1.4%Added
Raymond James Financial Inc38,037$582.3K0.00%+21,308+127.4%Added
Mirae Asset Global ETFs Holdings Ltd.38,448$587.0K0.00%+1,798+4.9%Added
State of Wisconsin Investment Board38,825$594.4K0.00%+20,274+109.3%Added
CIBC Private Wealth Group, LLC40,017$612.7K0.00%−12,546−23.9%Reduced
MetLife Investment Management40,212$615.6K0.00%+5,122+14.6%Added
Linden Thomas Advisory Services, LLC40,963$627.1K0.06%−1,809−4.2%Reduced
Franklin Resources Inc41,225$631.2K0.00%−3,455−7.7%Reduced
Profund Advisors LLC43,960$673.0K0.02%+26,375+150.0%Added
Quantinno Capital Management LP47,134$721.6K0.00%+2,032+4.5%Added
Russell Investments Group, Ltd.47,189$722.5K0.00%+35,185+293.1%Added
Schonfeld Strategic Advisors LLC47,848$732.6K0.00%+35,086+274.9%Added
BNP Paribas Arbitrage, SA48,687$745.4K0.00%−75,437−60.8%Reduced
DekaBank Deutsche Girozentrale31,800$775.0K0.00%00.0%Unchanged
Point72 Asset Management, L.P.55,339$847.2K0.00%+55,339New
ADAR1 Capital Management, LLC56,165$859.9K0.06%−72,700−56.4%Reduced
Great West Life Assurance Co57,164$875.0K0.00%−12,851−18.4%Reduced
California State Teachers Retirement System58,530$896.1K0.00%−73−0.1%Reduced
Alps Advisors Inc58,639$897.8K0.01%+24,606+72.3%Added
Tema ETFs LLC60,457$925.6K0.07%+60,457New
NEOS Investment Management LLC61,362$939.5K0.01%+61,362New
Prudential Financial Inc67,570$1.03M0.00%−4,465−6.2%Reduced
New York State Teachers Retirement System70,526$1.08M0.00%+10,900+18.3%Added
Intech Investment Management LLC70,612$1.08M0.01%+41,015+138.6%Added
Alliancebernstein L.P.72,090$1.10M0.00%00.0%Unchanged
TD Asset Management Inc77,802$1.19M0.00%−7,934−9.3%Reduced
Wells Fargo & Company79,667$1.22M0.00%+24,927+45.5%Added
Manufacturers Life Insurance Company, The82,942$1.25M0.00%−12,165−12.8%Reduced
Thrivent Financial for Lutherans82,828$1.27M0.00%−4,716−5.4%Reduced
Voloridge Investment Management, LLC87,717$1.34M0.00%+87,717New
Winton Group Ltd88,038$1.35M0.05%−37,417−29.8%Reduced
FMR LLC92,883$1.42M0.00%+18,953+25.6%Added
Rafferty Asset Management, LLC97,749$1.50M0.01%+27,873+39.9%Added
Essex LLC98,661$1.51M0.27%−1,200−1.2%Reduced
Seven Fleet Capital Management LP109,554$1.68M1.14%+109,554New
AQR Capital Management LLC112,271$1.72M0.00%+25,453+29.3%Added
Citigroup Inc112,275$1.72M0.00%+88,612+374.5%Added
Swiss National Bank119,600$1.83M0.00%+4,300+3.7%Added
UBS Asset Management Americas Inc119,789$1.83M0.00%−46,353−27.9%Reduced
Algert Global LLC124,400$1.90M0.03%−236,062−65.5%Reduced
SG Americas Securities, LLC128,345$1.97M0.00%+37,844+41.8%Added
Nuveen, LLC134,051$2.05M0.00%00.0%Unchanged
Ameriprise Financial Inc135,806$2.08M0.00%−10,877−7.4%Reduced
DCF Advisers, LLC154,736$2.37M0.78%−35,000−18.4%Reduced
Nantahala Capital Management, LLC164,639$2.52M0.15%−935,361−85.0%Reduced
Rhenman & Partners Asset Management AB165,750$2.54M0.24%00.0%Unchanged
Rhumbline Advisers165,797$2.54M0.00%−10,052−5.7%Reduced
American Century Companies Inc174,603$2.67M0.00%+1,221+0.7%Added
Trexquant Investment LP175,152$2.68M0.02%+39,042+28.7%Added
Susquehanna Portfolio Strategies, LLC191,463$2.93M0.05%+84,608+79.2%Added
Woodline Partners LP193,117$2.96M0.01%00.0%Unchanged
Nomura Asset Management International Inc.200,000$3.06M0.00%+200,000New
Deutsche Bank AG216,568$3.32M0.00%+171,335+378.8%Added
Public Sector Pension Investment Board247,242$3.79M0.01%−30,985−11.1%Reduced
Jacobs Levy Equity Management, Inc259,319$3.97M0.02%+259,319New
Invesco Ltd.265,820$4.07M0.00%+14,216+5.7%Added
Two Sigma Investments, LP268,737$4.11M0.01%−360,639−57.3%Reduced
JPMorgan Chase & Co303,979$4.65M0.00%−97,522−24.3%Reduced
Citadel Advisors LLC321,808$4.93M0.00%−159,360−33.1%Reduced
Principal Financial Group Inc340,326$5.21M0.00%−4,130−1.2%Reduced
Barclays PLC359,235$5.50M0.00%−241,110−40.2%Reduced
Bank of New York Mellon Corp410,650$6.29M0.00%−15,138−3.6%Reduced
Acadian Asset Management LLC411,725$6.30M0.01%−120,477−22.6%Reduced
Hudson Bay Capital Management LP425,000$6.51M0.04%−35,003−7.6%Reduced
Braidwell LP459,166$7.03M0.22%−787,114−63.2%Reduced
Erste Asset Management GmbH480,200$7.35M0.06%+100,000+26.3%Added
Toronto Dominion Bank491,000$7.52M0.01%+441,000+882.0%Added
Two Sigma Advisers, LP506,600$7.76M0.02%−303,600−37.5%Reduced
Panagora Asset Management Inc583,778$8.94M0.03%−37,251−6.0%Reduced
Millennium Management LLC594,435$9.10M0.01%−108,139−15.4%Reduced
Bank of America Corp629,408$9.64M0.00%−124,421−16.5%Reduced
UBS Group AG638,021$9.77M0.00%−537,246−45.7%Reduced
Northern Trust Corp674,657$10.3M0.00%−37,544−5.3%Reduced
Charles Schwab Investment Management Inc700,435$10.7M0.00%+12,166+1.8%Added
Lynx1 Capital Management LP705,558$10.8M2.19%+705,558New
Jefferies Financial Group Inc.720,440$11.0M0.09%+620,440+620.4%Added
Johnson & Johnson748,062$11.5M2.06%00.0%Unchanged
Goldman Sachs Group Inc753,258$11.5M0.00%−264,195−26.0%Reduced
Baker Bros. Advisors LP1,102,106$16.9M0.10%00.0%Unchanged
Dimensional Fund Advisors LP1,249,288$19.1M0.00%−339,675−21.4%Reduced
Legal & General Group Plc1,308,088$20.0M0.00%+35,088+2.8%Added
Defilade Capital Management, L.P.1,414,755$21.7M2.94%+1,414,755New
Morgan Stanley1,508,727$23.1M0.00%+607,890+67.5%Added
Price T Rowe Associates Inc1,601,762$24.5M0.00%−91,530−5.4%Reduced
Geode Capital Management, LLC1,752,918$26.8M0.00%+24,093+1.4%Added