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Twist Bioscience Corp

TWST
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001581280

In the last 90 days, Twist Bioscience Corp insiders filed 0 open-market purchases and 30 sales; 337 institutions reported holding it in 13F filings for Q2 2026, worth $7.85B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Twist Bioscience Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
244
+10 vs. Q3 2025
Shares held
75.0M
+1.35M (+1.8%) vs. Q3 2025
Total value
$2.38B
+$306.8M (+14.8%) vs. Q3 2025
New holders
48
75 more added
Sold out
38
77 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TWST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 244 institutions
Q1 2021: 240 institutionsQ2 2021: 245 institutionsQ3 2021: 238 institutionsQ4 2021: 237 institutionsQ1 2022: 213 institutionsQ2 2022: 205 institutionsQ3 2022: 221 institutionsQ4 2022: 199 institutionsQ1 2023: 203 institutionsQ2 2023: 194 institutionsQ3 2023: 196 institutionsQ4 2023: 219 institutionsQ1 2024: 238 institutionsQ2 2024: 263 institutionsQ3 2024: 246 institutionsQ4 2024: 247 institutionsQ1 2025: 263 institutionsQ2 2025: 244 institutionsQ3 2025: 239 institutionsQ4 2025: 244 institutionsQ1 2026: 281 institutionsQ2 2026: 337 institutions
Value heldQ4 2025: $2.38B
Q1 2021: $5.82BQ2 2021: $6.40BQ3 2021: $5.20BQ4 2021: $3.96BQ1 2022: $2.92BQ2 2022: $2.01BQ3 2022: $2.04BQ4 2022: $1.45BQ1 2023: $956.8MQ2 2023: $1.39BQ3 2023: $1.34BQ4 2023: $2.46BQ1 2024: $2.30BQ2 2024: $3.25BQ3 2024: $2.99BQ4 2024: $3.08BQ1 2025: $2.73BQ2 2025: $2.62BQ3 2025: $2.08BQ4 2025: $2.38BQ1 2026: $3.66BQ2 2026: $7.85B
Institutions holding TWST and their total value by quarter
QuarterHoldersValue
Q2 2026337$7.85B
Q1 2026281$3.66B
Q4 2025244$2.38B
Q3 2025239$2.08B
Q2 2025244$2.62B
Q1 2025263$2.73B
Q4 2024247$3.08B
Q3 2024246$2.99B
Q2 2024263$3.25B
Q1 2024238$2.30B
Q4 2023219$2.46B
Q3 2023196$1.34B
Q2 2023194$1.39B
Q1 2023203$956.8M
Q4 2022199$1.45B
Q3 2022221$2.04B
Q2 2022205$2.01B
Q1 2022213$2.92B
Q4 2021237$3.96B
Q3 2021238$5.20B
Q2 2021245$6.40B
Q1 2021240$5.82B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Twist Bioscience Corp; share changes are against Q3 2025.

Institutions holding TWST in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Pictet Asset Management Holding SA222,647$7.30M0.01%+115,880+108.5%Added
Jupiter Asset Management Ltd243,669$7.73M0.06%−1,429−0.6%Reduced
Osterweis Capital Management Inc256,878$8.15M0.34%+256,878New
Silvercrest Asset Management Group LLC269,093$8.54M0.06%+767+0.3%Added
SEI Investments Co270,099$8.57M0.01%−26,819−9.0%Reduced
Peregrine Capital Management LLC288,283$9.14M0.28%−3,870−1.3%Reduced
Nuveen, LLC290,556$9.22M0.00%−261,585−47.4%Reduced
Standard Life Aberdeen plc308,116$9.77M0.02%−12,167−3.8%Reduced
Davy Global Fund Management Ltd371,552$11.8M0.81%+105,701+39.8%Added
Blue Water Life Science Advisors, LLC383,000$12.1M7.63%+383,000New
Bank of America Corp399,354$12.7M0.00%−51,020−11.3%Reduced
Citigroup Inc401,282$12.7M0.01%+307,824+329.4%Added
BNP Paribas Arbitrage, SA415,609$13.2M0.01%+294,144+242.2%Added
Freshford Capital Management, LLC420,171$13.3M5.35%+420,171New
Northern Trust Corp504,838$16.0M0.00%−20,204−3.8%Reduced
StemPoint Capital LP518,355$16.4M2.82%+518,355New
Charles Schwab Investment Management Inc548,392$17.4M0.00%−25,240−4.4%Reduced
Balyasny Asset Management LLC579,370$18.4M0.03%+333,134+135.3%Added
New York State Common Retirement Fund591,180$18.8M0.03%+6,486+1.1%Added
Jennison Associates LLC618,933$19.6M0.01%−15,667−2.5%Reduced
UBS Group AG662,317$21.0M0.00%+147,389+28.6%Added
Wellington Management Group LLP813,122$25.8M0.00%+513,309+171.2%Added
Dimensional Fund Advisors LP815,369$25.9M0.01%+24,476+3.1%Added
Tao Capital Management LP828,815$26.3M22.63%00.0%Unchanged
American Century Companies Inc865,634$27.5M0.01%+27,570+3.3%Added
Morgan Stanley866,356$27.5M0.00%−625,750−41.9%Reduced
First Light Asset Management, LLC1,140,771$36.2M2.77%−54,112−4.5%Reduced
UBS Asset Management Americas Inc1,173,100$37.2M0.01%+49,403+4.4%Added
Baillie Gifford & Co1,276,195$40.5M0.03%+13,456+1.1%Added
Invesco Ltd.1,290,271$40.9M0.00%−504,872−28.1%Reduced
Thrivent Financial for Lutherans1,361,355$43.2M0.08%−101,730−7.0%Reduced
Geode Capital Management, LLC1,459,274$46.3M0.00%+10,861+0.7%Added
Millennium Management LLC1,497,746$47.5M0.03%−296,104−16.5%Reduced
Goldman Sachs Group Inc1,696,594$53.8M0.01%+69,574+4.3%Added
Soleus Capital Management, L.P.1,861,802$59.1M2.51%−4,432−0.2%Reduced
Nikko Asset Management Americas, Inc.1,902,829$60.3M0.70%−217,377−10.3%Reduced
Sumitomo Mitsui Trust Holdings, Inc.1,902,829$60.4M0.04%−217,377−10.3%Reduced
State Street Corp3,627,818$115.1M0.00%+538,755+17.4%Added
EdgePoint Investment Group Inc.5,377,991$170.6M1.40%+1,295,672+31.7%Added
Vanguard Group Inc5,776,198$183.2M0.00%+8,049+0.1%Added
Artisan Partners Limited Partnership5,830,205$184.9M0.28%−580,695−9.1%Reduced
BlackRock, Inc.5,894,972$187.0M0.00%−283,404−4.6%Reduced
William Blair Investment Management, LLC5,954,429$188.9M0.53%+1,812,146+43.7%Added
ARK Investment Management LLCSuperinvestorARK Invest7,559,495$239.8M1.59%+832,687+12.4%Added
Point72 Asset Management, L.P.0$00.00%−530,032−100.0%Sold out
Macquarie Group Ltd0$00.00%−82,248−100.0%Sold out
Man Group plc0$00.00%−76,124−100.0%Sold out
Prosight Management, LP0$00.00%−75,000−100.0%Sold out
Two Sigma Investments, LP0$00.00%−73,755−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−60,502−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−47,200−100.0%Sold out
Perbak Capital Partners LLP0$00.00%−46,415−100.0%Sold out
Marshall Wace, LLP0$00.00%−44,066−100.0%Sold out
Engineers Gate Manager LP0$00.00%−40,135−100.0%Sold out
JBF Capital, Inc.0$00.00%−37,100−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−25,465−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−23,827−100.0%Sold out
First Trust Advisors LP0$00.00%−20,413−100.0%Sold out
Prudential Financial Inc0$00.00%−18,974−100.0%Sold out
Lombard Odier Asset Management (USA) Corp0$00.00%−17,494−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−15,623−100.0%Sold out
Aigen Investment Management, LP0$00.00%−15,212−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−13,482−100.0%Sold out
Verition Fund Management LLC0$00.00%−12,908−100.0%Sold out
GTS Securities LLC0$00.00%−11,863−100.0%Sold out
STRS Ohio0$00.00%−10,900−100.0%Sold out
DRW Securities, LLC0$00.00%−9,523−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−9,454−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−8,609−100.0%Sold out
Bayforest Capital Ltd0$00.00%−2,436−100.0%Sold out
Quarry LP0$00.00%−1,000−100.0%Sold out
State of Wyoming0$00.00%−843−100.0%Sold out
Principal Securities, Inc.0$00.00%−593−100.0%Sold out
Advisory Services Network, LLC0$00.00%−402−100.0%Sold out
Optiver Holding B.V.0$00.00%−324−100.0%Sold out
Group One Trading, L.P.0$00.00%−252−100.0%Sold out
Halbert Hargrove Global Advisors, LLC0$00.00%−105−100.0%Sold out
Harbour Investments, Inc.0$00.00%−72−100.0%Sold out
Federation des caisses Desjardins du Quebec0$00.00%−46−100.0%Sold out
Washington Trust Advisors, Inc.0$00.00%−32−100.0%Sold out
Massmutual Trust Co FSB0$00.00%−12−100.0%Sold out
Ronald Blue Trust, Inc.0$00.00%−11−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Point72 Europe (London) LLP––––Not filed
Guerra Advisors Inc––––Not filed