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Tvardi Therapeutics, Inc.

TVRD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001346830

No open-market purchases or sales by Tvardi Therapeutics, Inc. insiders were filed in the last 90 days; 57 institutions reported holding it in 13F filings for Q2 2026, worth $4.24M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Tvardi Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
67
−6 vs. Q3 2025
Shares held
2.83M
+199.2K (+7.6%) vs. Q3 2025
Total value
$12.1M
−$90.1M (−88.2%) vs. Q3 2025
New holders
11
30 more added
Sold out
17
8 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TVRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 67 institutions
Q1 2021: 172 institutionsQ2 2021: 175 institutionsQ3 2021: 173 institutionsQ4 2021: 186 institutionsQ1 2022: 186 institutionsQ2 2022: 183 institutionsQ3 2022: 167 institutionsQ4 2022: 163 institutionsQ1 2023: 164 institutionsQ2 2023: 138 institutionsQ3 2023: 124 institutionsQ4 2023: 112 institutionsQ1 2024: 101 institutionsQ2 2024: 81 institutionsQ3 2024: 71 institutionsQ4 2024: 45 institutionsQ1 2025: 35 institutionsQ2 2025: 56 institutionsQ3 2025: 73 institutionsQ4 2025: 67 institutionsQ1 2026: 67 institutionsQ2 2026: 57 institutions
Value heldQ4 2025: $12.1M
Q1 2021: $703.5MQ2 2021: $444.0MQ3 2021: $457.1MQ4 2021: $368.9MQ1 2022: $385.5MQ2 2022: $317.9MQ3 2022: $323.6MQ4 2022: $364.7MQ1 2023: $166.4MQ2 2023: $83.3MQ3 2023: $45.6MQ4 2023: $18.1MQ1 2024: $21.5MQ2 2024: $4.56MQ3 2024: $4.17MQ4 2024: $6.59MQ1 2025: $3.21MQ2 2025: $44.9MQ3 2025: $102.2MQ4 2025: $12.1MQ1 2026: $8.60MQ2 2026: $4.24M
Institutions holding TVRD and their total value by quarter
QuarterHoldersValue
Q2 202657$4.24M
Q1 202667$8.60M
Q4 202567$12.1M
Q3 202573$102.2M
Q2 202556$44.9M
Q1 202535$3.21M
Q4 202445$6.59M
Q3 202471$4.17M
Q2 202481$4.56M
Q1 2024101$21.5M
Q4 2023112$18.1M
Q3 2023124$45.6M
Q2 2023138$83.3M
Q1 2023164$166.4M
Q4 2022163$364.7M
Q3 2022167$323.6M
Q2 2022183$317.9M
Q1 2022186$385.5M
Q4 2021186$368.9M
Q3 2021173$457.1M
Q2 2021175$444.0M
Q1 2021172$703.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Tvardi Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding TVRD in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Slate Path Capital LP704,118$3.03M0.04%00.0%Unchanged
Vanguard Group Inc424,821$1.83M0.00%+5,654+1.3%Added
BlackRock, Inc.391,000$1.68M0.00%+61,086+18.5%Added
American Financial Group Inc223,659$961.7K0.35%+223,659New
Geode Capital Management, LLC157,133$675.8K0.00%+9,214+6.2%Added
State Street Corp115,501$496.7K0.00%+52,637+83.7%Added
Renaissance Technologies LLC104,500$449.4K0.00%+74,325+246.3%Added
Silvercrest Asset Management Group LLC101,034$434.4K0.00%+78,668+351.7%Added
Morgan Stanley84,466$363.2K0.00%+80,680+2,131.0%Added
Duncan Williams Asset Management, LLC80,771$311.8K0.08%+58,741+266.6%Added
Squarepoint Ops LLC51,783$222.7K0.00%+43,619+534.3%Added
Northern Trust Corp47,882$205.9K0.00%+5,499+13.0%Added
Jane Street Group, LLC47,444$204.0K0.00%+47,444New
Farallon Capital Management, L.L.C.43,225$185.9K0.00%00.0%Unchanged
UBS Group AG35,555$152.9K0.00%−12,924−26.7%Reduced
Goldman Sachs Group Inc33,131$142.5K0.00%+9,102+37.9%Added
Bank of America Corp25,382$109.1K0.00%+10,020+65.2%Added
Quadrature Capital Ltd20,964$90.1K0.00%+20,964New
Bank of New York Mellon Corp18,146$78.0K0.00%+8,480+87.7%Added
Russell Investments Group, Ltd.15,966$68.7K0.00%+14,866+1,351.5%Added
XTX Topco Ltd12,838$55.2K0.00%+12,838New
Charles Schwab Investment Management Inc11,802$50.7K0.00%−3,472−22.7%Reduced
HRT Financial LP11,050$47.0K0.00%+11,050New
Two Sigma Investments, LP10,492$45.1K0.00%+10,492New
SRS Capital Advisors, Inc.8,400$36.1K0.00%+6,173+277.2%Added
Barclays PLC8,307$35.7K0.00%+1,638+24.6%Added
FMR LLC6,599$28.4K0.00%−75,622−92.0%Reduced
Wells Fargo & Company6,033$25.9K0.00%+2,479+69.8%Added
Rhumbline Advisers3,126$13.4K0.00%−856−21.5%Reduced
Deutsche Bank AG3,030$13.0K0.00%00.0%Unchanged
New York State Common Retirement Fund3,000$13.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,509$10.8K0.00%+2,158+614.8%Added
JPMorgan Chase & Co2,479$10.7K0.00%+562+29.3%Added
Mirae Asset Global ETFs Holdings Ltd.2,288$9.84K0.00%+88+4.0%Added
Simplex Trading, LLC1,418$6.10K0.00%−1,570−52.5%Reduced
BNP Paribas Arbitrage, SA1,259$5.41K0.00%+125+11.0%Added
Police & Firemen's Retirement System of New Jersey916$3.94K0.00%00.0%Unchanged
Legal & General Group Plc421$1.81K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.349$1.50K0.00%00.0%Unchanged
California State Teachers Retirement System331$1.42K0.00%+118+55.4%Added
The PNC Financial Services Group, Inc.294$1.26K0.00%+246+512.5%Added
Sterling Capital Management LLC292$1.26K0.00%+3+1.0%Added
Royal Bank of Canada294$1.00K0.00%−2,375−89.0%Reduced
Amalgamated Bank169$1.00K0.00%+52+44.4%Added
CWM, LLC206$1.00K0.00%+201+4,020.0%Added
Allworth Financial LP141$6070.00%+122+642.1%Added
Fortitude Family Office, LLC127$5460.00%+127New
Jones Financial Companies LLLP125$5380.00%+100+400.0%Added
Citigroup Inc123$5290.00%+51+70.8%Added
Group One Trading, L.P.114$4900.00%+100+714.3%Added
Advisor Group Holdings, Inc.29$1230.00%00.0%Unchanged
LRI Investments, LLC27$1160.00%−55−67.1%Reduced
McIlrath & Eck, LLC20$860.00%00.0%Unchanged
Harbour Investments, Inc.15$650.00%00.0%Unchanged
Leonteq Securities AG12$520.00%00.0%Unchanged
MAI Capital Management10$430.00%00.0%Unchanged
IFP Advisors, Inc6$260.00%+6New
International Assets Investment Management, LLC6$260.00%+6New
EverSource Wealth Advisors, LLC5$220.00%+5New
Truvestments Capital LLC4$170.00%00.0%Unchanged
SBI Securities Co., Ltd.4$170.00%00.0%Unchanged
Farther Finance Advisors, LLC3$130.00%00.0%Unchanged
Sound Income Strategies, LLC2$90.00%00.0%Unchanged
Larson Financial Group LLC2$90.00%+2New
Cornerstone Planning Group LLC1$40.00%−34−97.1%Reduced
Comerica Bank1$40.00%00.0%Unchanged
Front Row Advisors LLC1$40.00%00.0%Unchanged
683 Capital Management, LLC0$00.00%−176,030−100.0%Sold out
Vestal Point Capital, LP0$00.00%−167,000−100.0%Sold out
Invesco Ltd.0$00.00%−82,614−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−65,000−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−20,189−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−19,132−100.0%Sold out
Monaco Asset Management SAM0$00.00%−13,590−100.0%Sold out
Nuveen, LLC0$00.00%−5,951−100.0%Sold out
MetLife Investment Management0$00.00%−2,819−100.0%Sold out
Diadema Partners LP0$00.00%−2,185−100.0%Sold out
State of Wyoming0$00.00%−1,281−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−1,000−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−500−100.0%Sold out
GWM Advisors LLC0$00.00%−8−100.0%Sold out
Creative Financial Designs Inc0$00.00%−6−100.0%Sold out
Painted Porch Advisors LLC0$00.00%−6−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−4−100.0%Sold out