Tvardi Therapeutics, Inc.
TVRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001346830
No open-market purchases or sales by Tvardi Therapeutics, Inc. insiders were filed in the last 90 days; 57 institutions reported holding it in 13F filings for Q2 2026, worth $4.24M in total; no superinvestor holds it.
Holders of 5% or more of TVRD
Holders whose latest Schedule 13D or 13G filing reports 5% or more of Tvardi Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| Sporos Bioventures LLC | 13G | 8.95%837.6K shares | New | Aug 8, 20251 filing | Aug 8, 2025 | SEC |
| Solas Tvardi Sidecar LLC | 13G | 8.10%761.3K shares | New | Apr 22, 20251 filing | Apr 22, 2025 | SEC |
| Slate Path Capital LP | 13G | 7.50%704.1K shares | New | Aug 14, 20251 filing | Aug 14, 2025 | SEC |
| Tweardy David John | 13G | 7.00%652.4K shares | New | May 2, 20251 filing | May 2, 2025 | SEC |
Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.
13D and 13G filings
32 Schedule 13D and 13G filings on Tvardi Therapeutics, Inc., newest first, including old-format filings without a stake.
| Filed (ET) | Filer | Form | Stake | Change | Event date | Filing |
|---|---|---|---|---|---|---|
| Feb 17, 20265:30 PM ET | DePinho Ronald A | 13G/A | 4.50%426.2K shares | −2.20 ppfrom 6.70%Below 5% | Dec 31, 2025 | SEC |
| Nov 14, 20255:01 PM ET | DePinho Ronald A | 13G/A | 6.70%626.2K shares | −1.60 ppfrom 8.30% | Sep 30, 2025 | SEC |
| Aug 14, 20254:15 PM ET | Slate Path Capital LPand 1 other | 13G | 7.50%704.1K shares | New | Jun 30, 2025 | SEC |
| Aug 8, 20254:30 PM ET | Sporos Bioventures LLC | 13G | 8.95%837.6K shares | New | Apr 15, 2025 | SEC |
| Aug 5, 20258:04 PM ET | Tweardy Samuel David | 13G/A | 3.40%315.7K shares | −6.70 ppfrom 10.10%Below 5% | Jul 7, 2025 | SEC |
| Jun 2, 20259:04 AM ET | DePinho Ronald A | 13G | 8.30%781.0K shares | New | Apr 15, 2025 | SEC |
| May 2, 20254:24 PM ET | Tweardy Samuel David | 13G | 10.10%947.0K shares | New | Apr 15, 2025 | SEC |
| May 2, 20254:21 PM ET | Tweardy David John | 13G | 7.00%652.4K shares | New | Apr 15, 2025 | SEC |
| Apr 22, 20252:26 PM ET | Solas Tvardi Sidecar LLCand 2 others | 13G | 8.10%761.3K shares | New | Apr 15, 2025 | SEC |
| Apr 16, 20254:15 PM ET | Vifor (International) Ltdand 1 other | 13D/A | 2.20%205.5K shares | −11.30 ppfrom 13.50%Below 5% | Apr 15, 2025 | SEC |
| Dec 18, 20245:10 PM ET | Vifor (International) Ltdand 1 other | 13D/A | 13.50%7.40M shares | – | Dec 17, 2024 | SEC |
| Oct 30, 2024 | Vifor (International) Ltd | 13DOld format | – | – | – | SEC |
| Jul 8, 20244:32 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Feb 13, 2024 | Bain Capital Life Sciences Opportunities III, LP | 13G/AOld format | – | – | – | SEC |
| Feb 13, 2024 | Vanguard Group Inc | 13G/AOld format | – | – | – | SEC |
| Jan 29, 20243:26 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Jul 25, 2023 | Vifor (International) Ltd | 13G/AOld format | – | – | – | SEC |
| Jul 7, 20234:35 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Feb 9, 2023 | Vanguard Group Inc | 13G/AOld format | – | – | – | SEC |
| Jan 26, 20238:52 AM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Jan 20, 20239:43 AM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Nov 18, 2022 | Bain Capital Life Sciences Opportunities III, LP | 13GOld format | – | New | – | SEC |
| Feb 15, 2022 | First Manhattan Co | 13G/AOld format | – | – | – | SEC |
| Feb 14, 2022 | RHO Ventures VI LP | 13G/AOld format | – | – | – | SEC |
| Feb 9, 2022 | Vanguard Group Inc | 13GOld format | – | New | – | SEC |
| Jan 28, 20221:54 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Oct 21, 2021 | Vifor (International) Ltd | 13G/AOld format | – | – | – | SEC |
| May 7, 20215:09 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Feb 16, 2021 | First Manhattan Co | 13GOld format | – | New | – | SEC |
| Feb 16, 2021 | Price T Rowe Associates Inc | 13G/AOld format | – | – | – | SEC |
| Feb 12, 2021 | RHO Ventures VI LP | 13G/AOld format | – | – | – | SEC |
| Jan 28, 20215:56 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
Form 144: proposed insider sales
Notices from officers, directors and other affiliates planning to sell Tvardi Therapeutics, Inc. shares.
No Form 144 notices for Tvardi Therapeutics, Inc. are on file.