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Trevi Therapeutics, Inc.

TRVI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001563880

In the last 90 days, Trevi Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 218 institutions reported holding it in 13F filings for Q2 2026, worth $2.76B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Trevi Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
+17 vs. Q1 2025
Shares held
114.7M
+26.5M (+30.1%) vs. Q1 2025
Total value
$627.2M
+$72.8M (+13.1%) vs. Q1 2025
New holders
40
65 more added
Sold out
23
31 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TRVI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 154 institutions
Q1 2021: 19 institutionsQ2 2021: 17 institutionsQ3 2021: 18 institutionsQ4 2021: 17 institutionsQ1 2022: 23 institutionsQ2 2022: 32 institutionsQ3 2022: 40 institutionsQ4 2022: 37 institutionsQ1 2023: 36 institutionsQ2 2023: 53 institutionsQ3 2023: 55 institutionsQ4 2023: 63 institutionsQ1 2024: 80 institutionsQ2 2024: 77 institutionsQ3 2024: 93 institutionsQ4 2024: 110 institutionsQ1 2025: 137 institutionsQ2 2025: 154 institutionsQ3 2025: 164 institutionsQ4 2025: 184 institutionsQ1 2026: 198 institutionsQ2 2026: 218 institutions
Value heldQ2 2025: $627.2M
Q1 2021: $35.6MQ2 2021: $28.1MQ3 2021: $17.4MQ4 2021: $10.3MQ1 2022: $32.9MQ2 2022: $80.8MQ3 2022: $70.5MQ4 2022: $83.3MQ1 2023: $80.4MQ2 2023: $116.7MQ3 2023: $106.1MQ4 2023: $70.0MQ1 2024: $177.9MQ2 2024: $166.6MQ3 2024: $194.1MQ4 2024: $329.5MQ1 2025: $554.3MQ2 2025: $627.2MQ3 2025: $1.18BQ4 2025: $1.63BQ1 2026: $1.61BQ2 2026: $2.76B
Institutions holding TRVI and their total value by quarter
QuarterHoldersValue
Q2 2026218$2.76B
Q1 2026198$1.61B
Q4 2025184$1.63B
Q3 2025164$1.18B
Q2 2025154$627.2M
Q1 2025137$554.3M
Q4 2024110$329.5M
Q3 202493$194.1M
Q2 202477$166.6M
Q1 202480$177.9M
Q4 202363$70.0M
Q3 202355$106.1M
Q2 202353$116.7M
Q1 202336$80.4M
Q4 202237$83.3M
Q3 202240$70.5M
Q2 202232$80.8M
Q1 202223$32.9M
Q4 202117$10.3M
Q3 202118$17.4M
Q2 202117$28.1M
Q1 202119$35.6M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Trevi Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding TRVI in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Wellington Management Group LLP171,982$940.7K0.00%+44,530+34.9%Added
Diadema Partners LP185,830$1.02M0.63%+5,830+3.2%Added
Charles Schwab Investment Management Inc225,935$1.24M0.00%+18,417+8.9%Added
Prudential Financial Inc226,381$1.24M0.00%+226,381New
Goldman Sachs Group Inc299,045$1.64M0.00%+87,172+41.1%Added
Rosalind Advisors, Inc.300,000$1.64M0.79%−312,901−51.1%Reduced
Invesco Ltd.322,339$1.76M0.00%−530,646−62.2%Reduced
Tejara Capital Ltd326,395$1.79M0.83%+146,879+81.8%Added
UBS Group AG354,225$1.94M0.00%+261,192+280.8%Added
FMR LLC368,529$2.02M0.00%+362,528+6,041.1%Added
Opaleye Management Inc.390,000$2.13M0.43%−405,000−50.9%Reduced
Qube Research & Technologies Ltd447,852$2.45M0.00%+321,623+254.8%Added
EAM Investors, LLC486,624$2.66M0.40%−64,295−11.7%Reduced
Renaissance Technologies LLC489,300$2.68M0.00%+400,400+450.4%Added
Acuta Capital Partners, LLC493,735$2.70M3.77%−292,226−37.2%Reduced
Barclays PLC515,476$2.82M0.00%+377,544+273.7%Added
Burkehill Global Management, LP525,000$2.87M0.21%+525,000New
Silverarc Capital Management, LLC539,587$2.95M0.60%+9,587+1.8%Added
Panagora Asset Management Inc569,702$3.12M0.01%+229,798+67.6%Added
Northern Trust Corp576,471$3.15M0.00%+10,274+1.8%Added
Alyeska Investment Group, L.P.650,000$3.56M0.01%+650,000New
Soleus Capital Management, L.P.700,000$3.83M0.26%+700,000New
Sphera Funds Management Ltd.799,957$4.38M1.14%+799,957New
Royal Bank of Canada824,180$4.51M0.00%+805,082+4,215.5%Added
MAI Capital Management847,553$4.64M0.03%−537,497−38.8%Reduced
Logos Global Management LP850,000$4.65M0.62%+425,285+100.1%Added
J. Goldman & Co LP979,098$5.36M0.17%+777,991+386.9%Added
Morgan Stanley1,024,011$5.60M0.00%+529,444+107.1%Added
Raymond James Financial Inc1,076,683$5.89M0.00%+567,304+111.4%Added
Bank of America Corp1,097,497$6.00M0.00%+965,732+732.9%Added
Pivotal bioVenture Partners Investment Advisor LLC1,146,110$6.27M3.89%+1,146,110New
Artia Global Partners LP1,311,840$7.18M1.85%+1,311,840New
Citadel Advisors LLC1,319,266$7.22M0.01%+1,319,266New
Eventide Asset Management, LLC1,381,324$7.56M0.13%+1,381,324New
Viking Global Investors LPSuperinvestorViking Global Investors1,543,000$8.44M0.02%−1,684,792−52.2%Reduced
Point72 Asset Management, L.P.1,728,676$9.46M0.02%−639,329−27.0%Reduced
Geode Capital Management, LLC1,786,845$9.78M0.00%+171,980+10.6%Added
State Street Corp1,832,920$10.0M0.00%+408,414+28.7%Added
Acorn Capital Advisors, LLC2,144,844$11.7M7.67%00.0%Unchanged
Balyasny Asset Management LLC2,354,402$12.9M0.03%+595,783+33.9%Added
Marshall Wace, LLP2,477,916$13.6M0.02%−76,305−3.0%Reduced
Affinity Asset Advisors, LLC2,534,058$13.9M2.05%+1,284,058+102.7%Added
OrbiMed Advisors LLC3,308,400$18.1M0.46%+2,188,400+195.4%Added
MPM Oncology Impact Management LP3,406,955$18.6M3.23%−21,411−0.6%Reduced
Octagon Capital Advisors LP3,672,000$20.1M4.41%+350,000+10.5%Added
Siren, L.L.C.3,938,793$21.5M1.11%+1,075,000+37.5%Added
Woodline Partners LP4,046,435$22.1M0.12%+1,988,623+96.6%Added
Alliancebernstein L.P.4,281,355$23.4M0.01%+4,259,015+19,064.5%Added
Vivo Capital, LLC4,487,903$24.5M2.51%+1,000,000+28.7%Added
Vanguard Group Inc5,316,691$29.1M0.00%+1,478,659+38.5%Added
BlackRock, Inc.8,205,006$44.9M0.00%+2,892,464+54.4%Added
Rubric Capital Management LP8,531,860$46.7M0.75%+3,993,325+88.0%Added
Frazier Life Sciences Management, L.P.10,259,409$56.1M2.24%00.0%Unchanged
NEA Management Company, LLC13,222,228$72.3M5.44%+1,851,852+16.3%Added
Armistice Capital, LLC0$00.00%−2,988,000−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−686,219−100.0%Sold out
VR Adviser, LLC0$00.00%−615,506−100.0%Sold out
Ikarian Capital, LLC0$00.00%−575,000−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−440,000−100.0%Sold out
Suvretta Capital Management, LLC0$00.00%−340,164−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−164,740−100.0%Sold out
Exome Asset Management LLC0$00.00%−163,738−100.0%Sold out
Jump Financial, LLC0$00.00%−160,815−100.0%Sold out
American Century Companies Inc0$00.00%−79,796−100.0%Sold out
Braidwell LP0$00.00%−72,083−100.0%Sold out
Group One Trading, L.P.0$00.00%−58,679−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−49,937−100.0%Sold out
Wexford Capital LP0$00.00%−40,000−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−36,503−100.0%Sold out
SG Americas Securities, LLC0$00.00%−24,661−100.0%Sold out
Atom Investors LP0$00.00%−23,996−100.0%Sold out
CIBC World Markets Corp0$00.00%−16,534−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−13,200−100.0%Sold out
Quantbot Technologies LP0$00.00%−1,051−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−78−100.0%Sold out
Rothschild Investment LLC0$00.00%−40−100.0%Sold out
Allworth Financial LP0$00.00%−20−100.0%Sold out