Sutro Biopharma, Inc.
STRO- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001382101
No open-market purchases or sales by Sutro Biopharma, Inc. insiders were filed in the last 90 days; 100 institutions reported holding it in 13F filings for Q2 2026, worth $545.7M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Sutro Biopharma, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 63
- −22 vs. Q3 2025
- Shares held
- 5.61M
- −47.8M (−89.5%) vs. Q3 2025
- Total value
- $65.0M
- +$18.6M (+40.0%) vs. Q3 2025
- New holders
- 11
- 0 more added
- Sold out
- 33
- 52 more reduced
3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting STRO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 100 | $545.7M |
| Q1 2026 | 78 | $358.9M |
| Q4 2025 | 63 | $65.0M |
| Q3 2025 | 88 | $46.4M |
| Q2 2025 | 101 | $39.8M |
| Q1 2025 | 113 | $40.0M |
| Q4 2024 | 123 | $117.6M |
| Q3 2024 | 130 | $216.6M |
| Q2 2024 | 119 | $185.2M |
| Q1 2024 | 117 | $308.2M |
| Q4 2023 | 114 | $240.0M |
| Q3 2023 | 109 | $194.3M |
| Q2 2023 | 120 | $251.6M |
| Q1 2023 | 116 | $247.9M |
| Q4 2022 | 119 | $403.7M |
| Q3 2022 | 113 | $286.6M |
| Q2 2022 | 115 | $240.9M |
| Q1 2022 | 114 | $342.2M |
| Q4 2021 | 117 | $599.0M |
| Q3 2021 | 120 | $752.5M |
| Q2 2021 | 124 | $766.7M |
| Q1 2021 | 138 | $1.01B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Sutro Biopharma, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Affinity Asset Advisors, LLC | 748,382 | $8.66M | 0.62% | −4,340−0.6% | Reduced |
| Kynam Capital Management, LP | 479,590 | $5.55M | 0.36% | −4,608,509−90.6% | Reduced |
| Millennium Management LLC | 418,196 | $4.84M | 0.00% | −4,106,154−90.8% | Reduced |
| Vanguard Group Inc | 375,786 | $4.35M | 0.00% | −3,307,200−89.8% | Reduced |
| Acadian Asset Management LLC | 337,953 | $3.91M | 0.01% | −3,051,369−90.0% | Reduced |
| Velan Capital Investment Management LP | 312,000 | $3.61M | 2.10% | −2,808,000−90.0% | Reduced |
| Merck & Co., Inc. | 272,351 | $3.15M | 1.14% | −2,451,158−90.0% | Reduced |
| Vestal Point Capital, LP | 243,000 | $2.81M | 0.10% | −2,357,000−90.7% | Reduced |
| Balyasny Asset Management LLC | 230,049 | $2.66M | 0.00% | +230,049 | New |
| Samsara BioCapital, LLC | 204,503 | $2.37M | 0.24% | −1,992,311−90.7% | Reduced |
| Adage Capital Partners GP, L.L.C. | 200,000 | $2.31M | 0.00% | −1,800,000−90.0% | Reduced |
| Eversept Partners, LP | 193,571 | $2.24M | 0.13% | −2,097,742−91.6% | Reduced |
| Opaleye Management Inc. | 190,671 | $2.21M | 0.29% | +190,671 | New |
| Point72 Asset Management, L.P. | 179,088 | $2.07M | 0.00% | +179,088 | New |
| Tang Capital Management LLC | 139,617 | $1.62M | 0.08% | −2,689,100−95.1% | Reduced |
| Renaissance Technologies LLC | 122,865 | $1.42M | 0.00% | −1,301,932−91.4% | Reduced |
| BlackRock, Inc. | 117,437 | $1.36M | 0.00% | −1,570,443−93.0% | Reduced |
| Gsa Capital Partners LLP | 89,067 | $1.03M | 0.09% | −85,776−49.1% | Reduced |
| Marshall Wace, LLP | 85,615 | $990.6K | 0.00% | −32,828−27.7% | Reduced |
| Geode Capital Management, LLC | 83,979 | $972.0K | 0.00% | −736,969−89.8% | Reduced |
| Spruce Street Capital LP | 75,594 | $874.6K | 0.29% | +75,594 | New |
| Acuta Capital Partners, LLC | 67,451 | $780.4K | 0.53% | +67,451 | New |
| ADAR1 Capital Management, LLC | 67,077 | $776.1K | 0.06% | +67,077 | New |
| Two Sigma Investments, LP | 46,492 | $537.9K | 0.00% | −350,293−88.3% | Reduced |
| Fisher Asset Management, LLC | 35,305 | $408.5K | 0.00% | −317,644−90.0% | Reduced |
| State Street Corp | 34,266 | $396.5K | 0.00% | −308,386−90.0% | Reduced |
| Citadel Advisors LLC | 32,085 | $371.2K | 0.00% | +32,085 | New |
| RBF Capital, LLC | 30,544 | $353.4K | 0.01% | −122,170−80.0% | Reduced |
| Shay Capital LLC | 24,255 | $280.6K | 0.05% | −287,796−92.2% | Reduced |
| Jane Street Group, LLC | 22,945 | $265.5K | 0.00% | +22,945 | New |
| AQR Capital Management LLC | 18,034 | $208.7K | 0.00% | −336,415−94.9% | Reduced |
| Two Sigma Advisers, LP | 17,580 | $203.4K | 0.00% | −221,820−92.7% | Reduced |
| AJU IB Investment Co., Ltd. | 17,500 | $202.5K | 0.89% | −157,500−90.0% | Reduced |
| Invesco Ltd. | 16,970 | $196.3K | 0.00% | −117,949−87.4% | Reduced |
| Morgan Stanley | 15,922 | $184.2K | 0.00% | −225,963−93.4% | Reduced |
| Goldman Sachs Group Inc | 15,669 | $181.3K | 0.00% | −72,442−82.2% | Reduced |
| Northern Trust Corp | 14,379 | $166.4K | 0.00% | −107,736−88.2% | Reduced |
| Omers Administration Corp | 11,023 | $127.5K | 0.00% | −84,127−88.4% | Reduced |
| State of Tennessee, Treasury Department | 7,400 | $110.6K | 0.00% | +7,400 | New |
| UBS Group AG | 7,870 | $91.1K | 0.00% | −1,837,969−99.6% | Reduced |
| Bank of America Corp | 4,212 | $48.7K | 0.00% | −115,222−96.5% | Reduced |
| CWM, LLC | 1,499 | $17.0K | 0.00% | −23,737−94.1% | Reduced |
| Advisor Group Holdings, Inc. | 1,338 | $15.5K | 0.00% | −19,811−93.7% | Reduced |
| FMR LLC | 1,108 | $12.8K | 0.00% | −10,756−90.7% | Reduced |
| Citigroup Inc | 1,043 | $12.1K | 0.00% | −74,334−98.6% | Reduced |
| FNY Investment Advisers, LLC | 1,000 | $11.0K | 0.00% | −9,000−90.0% | Reduced |
| JPMorgan Chase & Co | 741 | $8.57K | 0.00% | −151,575−99.5% | Reduced |
| UMA Financial Services, Inc. | 182 | $2.11K | 0.00% | −1,122−86.0% | Reduced |
| BNP Paribas Arbitrage, SA | 111 | $1.28K | 0.00% | −1,630−93.6% | Reduced |
| Wells Fargo & Company | 100 | $1.16K | 0.00% | +100 | New |
| The PNC Financial Services Group, Inc. | 62 | $717 | 0.00% | −552−89.9% | Reduced |
| Fortitude Family Office, LLC | 56 | $648 | 0.00% | +56 | New |
| Bogart Wealth, LLC | 50 | $579 | 0.00% | −450−90.0% | Reduced |
| Parallel Advisors, LLC | 47 | $544 | 0.00% | −418−89.9% | Reduced |
| Nisa Investment Advisors, LLC | 44 | $509 | 0.00% | −396−90.0% | Reduced |
| EverSource Wealth Advisors, LLC | 31 | $359 | 0.00% | −423−93.2% | Reduced |
| HighMark Wealth Management LLC | 23 | $266 | 0.00% | −202−89.8% | Reduced |
| Essential Partners LLC | 4 | $46 | 0.00% | −208−98.1% | Reduced |
| SRS Capital Advisors, Inc. | 3 | $35 | 0.00% | −3,840−99.9% | Reduced |
| Comerica Bank | 3 | $35 | 0.00% | −46−93.9% | Reduced |
| Group One Trading, L.P. | 2 | $23 | 0.00% | −18−90.0% | Reduced |
| Royal Bank of Canada | 11 | $0 | 0.00% | −258,980−100.0% | Reduced |
| Avion Wealth | 72 | $0 | 0.00% | −644−89.9% | Reduced |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −6,488,324−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −445,750−100.0% | Sold out |
| DAFNA Capital Management LLC | 0 | $0 | 0.00% | −437,079−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −197,516−100.0% | Sold out |
| LPL Financial LLC | 0 | $0 | 0.00% | −142,883−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −103,592−100.0% | Sold out |
| Standard Life Aberdeen plc | 0 | $0 | 0.00% | −69,389−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −68,061−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −65,226−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −63,776−100.0% | Sold out |
| JustInvest LLC | 0 | $0 | 0.00% | −60,184−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −59,752−100.0% | Sold out |
| Vontobel Holding Ltd. | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Bridgeway Capital Management, LLC | 0 | $0 | 0.00% | −42,900−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −35,500−100.0% | Sold out |
| Bluefin Capital Management, LLC | 0 | $0 | 0.00% | −34,934−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −24,017−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −19,131−100.0% | Sold out |
| China Universal Asset Management Co., Ltd. | 0 | $0 | 0.00% | −14,860−100.0% | Sold out |
| Ground Swell Capital, LLC | 0 | $0 | 0.00% | −14,345−100.0% | Sold out |
| Quantinno Capital Management LP | 0 | $0 | 0.00% | −11,139−100.0% | Sold out |
| Revolve Wealth Partners, LLC | 0 | $0 | 0.00% | −11,002−100.0% | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −3,277−100.0% | Sold out |
| Barclays PLC | 0 | $0 | 0.00% | −2,767−100.0% | Sold out |
| Rockefeller Capital Management L.P. | 0 | $0 | 0.00% | −2,365−100.0% | Sold out |
| GF Fund Management Co. Ltd. | 0 | $0 | 0.00% | −1,918−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −769−100.0% | Sold out |
| Bare Financial Services, Inc | 0 | $0 | 0.00% | −549−100.0% | Sold out |
| Jones Financial Companies LLLP | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −147−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −45−100.0% | Sold out |
| IFP Advisors, Inc | 0 | $0 | 0.00% | −21−100.0% | Sold out |
| SBI Securities Co., Ltd. | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |
| Accredited Wealth Management, LLC | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |