Stoke Therapeutics, Inc.
STOK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001623526
In the last 90 days, Stoke Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 197 institutions reported holding it in 13F filings for Q2 2026, worth $2.49B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Stoke Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 183
- +33 vs. Q3 2025
- Shares held
- 67.0M
- +1.55M (+2.4%) vs. Q3 2025
- Total value
- $2.13B
- +$605.0M (+39.8%) vs. Q3 2025
- New holders
- 46
- 54 more added
- Sold out
- 13
- 58 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting STOK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 197 | $2.49B |
| Q1 2026 | 198 | $2.31B |
| Q4 2025 | 183 | $2.13B |
| Q3 2025 | 151 | $1.57B |
| Q2 2025 | 134 | $744.0M |
| Q1 2025 | 126 | $421.6M |
| Q4 2024 | 130 | $640.4M |
| Q3 2024 | 118 | $715.5M |
| Q2 2024 | 115 | $828.5M |
| Q1 2024 | 103 | $731.7M |
| Q4 2023 | 81 | $236.9M |
| Q3 2023 | 97 | $173.1M |
| Q2 2023 | 100 | $494.8M |
| Q1 2023 | 97 | $371.8M |
| Q4 2022 | 107 | $371.8M |
| Q3 2022 | 105 | $544.4M |
| Q2 2022 | 92 | $569.4M |
| Q1 2022 | 99 | $870.6M |
| Q4 2021 | 94 | $849.6M |
| Q3 2021 | 90 | $492.4M |
| Q2 2021 | 97 | $680.3M |
| Q1 2021 | 106 | $1.49B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Stoke Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Cresset Asset Management, LLC | 26,325 | $835.6K | 0.00% | −411−1.5% | Reduced |
| Readystate Asset Management LP | 29,059 | $922.3K | 0.04% | +29,059 | New |
| AQR Capital Management LLC | 29,467 | $935.3K | 0.00% | +354+1.2% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 32,515 | $1.03M | 0.00% | −17,948−35.6% | Reduced |
| Profund Advisors LLC | 33,388 | $1.06M | 0.03% | +33,388 | New |
| Deutsche Bank AG | 33,406 | $1.06M | 0.00% | +9,176+37.9% | Added |
| Canada Pension Plan Investment Board | 35,200 | $1.12M | 0.00% | +35,200 | New |
| Legal & General Group Plc | 36,366 | $1.15M | 0.00% | −1,417−3.8% | Reduced |
| California State Teachers Retirement System | 37,127 | $1.18M | 0.00% | +5,057+15.8% | Added |
| Harvest Investment Services, LLC | 38,347 | $1.22M | 0.23% | +38,347 | New |
| Kennondale Capital Management LLC | 38,731 | $1.23M | 0.90% | −31,001−44.5% | Reduced |
| Alliancebernstein L.P. | 40,630 | $1.29M | 0.00% | 00.0% | Unchanged |
| Platinum Investment Management Ltd | 40,815 | $1.30M | 0.30% | +7,914+24.1% | Added |
| Victory Capital Management Inc | 41,140 | $1.31M | 0.00% | +41,140 | New |
| Creative Planning | 41,712 | $1.32M | 0.00% | −1,592−3.7% | Reduced |
| Nomura Holdings Inc | 44,352 | $1.41M | 0.00% | −36,857−45.4% | Reduced |
| Susquehanna International Group, LLP | 46,022 | $1.46M | 0.00% | +19,230+71.8% | Added |
| Wells Fargo & Company | 49,585 | $1.57M | 0.00% | +21,514+76.6% | Added |
| D. E. Shaw & Co., Inc. | 49,901 | $1.58M | 0.00% | −2,712−5.2% | Reduced |
| Woodline Partners LP | 50,120 | $1.59M | 0.01% | −45,000−47.3% | Reduced |
| Privium Fund Management B.V. | 55,000 | $1.75M | 0.32% | +55,000 | New |
| UBS Asset Management Americas Inc | 57,212 | $1.82M | 0.00% | −18,646−24.6% | Reduced |
| Rhumbline Advisers | 62,414 | $1.98M | 0.00% | −5,890−8.6% | Reduced |
| Hussman Strategic Advisors, Inc. | 63,000 | $2.00M | 0.48% | +63,000 | New |
| Schonfeld Strategic Advisors LLC | 63,109 | $2.00M | 0.01% | −174,906−73.5% | Reduced |
| Alps Advisors Inc | 66,502 | $2.11M | 0.01% | +21,838+48.9% | Added |
| Jane Street Group, LLC | 67,112 | $2.13M | 0.00% | +67,112 | New |
| Principal Financial Group Inc | 70,282 | $2.23M | 0.00% | +25,077+55.5% | Added |
| Palo Alto Investors LP | 72,022 | $2.29M | 0.32% | −33,405−31.7% | Reduced |
| Alyeska Investment Group, L.P. | 75,000 | $2.38M | 0.01% | +75,000 | New |
| Swiss National Bank | 75,700 | $2.40M | 0.00% | +1,600+2.2% | Added |
| Quantedge Capital Pte Ltd | 87,200 | $2.77M | 1.32% | +47,200+118.0% | Added |
| Penserra Capital Management LLC | 88,507 | $2.81M | 0.03% | −62,092−41.2% | Reduced |
| Rafferty Asset Management, LLC | 90,193 | $2.86M | 0.01% | +54,866+155.3% | Added |
| Nuveen, LLC | 104,261 | $3.31M | 0.00% | −1,733−1.6% | Reduced |
| DAFNA Capital Management LLC | 108,875 | $3.46M | 0.80% | −60,916−35.9% | Reduced |
| American Century Companies Inc | 115,118 | $3.65M | 0.00% | +16,026+16.2% | Added |
| HighVista Strategies LLC | 115,539 | $3.67M | 0.94% | +115,539 | New |
| EAM Investors, LLC | 117,823 | $3.74M | 0.42% | −2,358−2.0% | Reduced |
| Gilder Gagnon Howe & Co LLC | 122,448 | $3.89M | 0.04% | −32,718−21.1% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 126,350 | $4.01M | 0.06% | 00.0% | Unchanged |
| Franklin Resources Inc | 132,222 | $4.20M | 0.00% | +16,389+14.1% | Added |
| Bank of New York Mellon Corp | 140,802 | $4.47M | 0.00% | +20,366+16.9% | Added |
| Barclays PLC | 150,945 | $4.79M | 0.00% | +43,222+40.1% | Added |
| First Trust Advisors LP | 162,679 | $5.16M | 0.00% | +10,380+6.8% | Added |
| UBS Group AG | 169,713 | $5.39M | 0.00% | −136,324−44.5% | Reduced |
| Granahan Investment Management Inc | 191,397 | $6.07M | 0.26% | −62,502−24.6% | Reduced |
| Bank of America Corp | 206,164 | $6.54M | 0.00% | −43,287−17.4% | Reduced |
| Rhenman & Partners Asset Management AB | 216,000 | $6.86M | 0.64% | −34,000−13.6% | Reduced |
| Baillie Gifford & Co | 246,900 | $7.84M | 0.01% | +246,900 | New |
| Invesco Ltd. | 259,543 | $8.24M | 0.00% | +51,468+24.7% | Added |
| Birchview Capital, LP | 260,000 | $8.25M | 4.83% | +50,000+23.8% | Added |
| JPMorgan Chase & Co | 277,930 | $8.82M | 0.00% | +253,554+1,040.2% | Added |
| Price T Rowe Associates Inc | 372,334 | $11.8M | 0.00% | +321,071+626.3% | Added |
| Erste Asset Management GmbH | 396,000 | $12.6M | 0.11% | 00.0% | Unchanged |
| Northern Trust Corp | 403,168 | $12.8M | 0.00% | −11,749−2.8% | Reduced |
| Charles Schwab Investment Management Inc | 410,906 | $13.0M | 0.00% | +7,997+2.0% | Added |
| Parkman Healthcare Partners LLC | 430,155 | $13.7M | 1.30% | +180,155+72.1% | Added |
| Candriam Luxembourg S.C.A. | 446,690 | $14.2M | 0.07% | +446,690 | New |
| Tang Capital Management LLC | 500,000 | $15.9M | 0.78% | 00.0% | Unchanged |
| Opaleye Management Inc. | 695,000 | $22.1M | 2.91% | +12,983+1.9% | Added |
| Wellington Management Group LLP | 735,799 | $23.4M | 0.00% | −1,954−0.3% | Reduced |
| MPM Oncology Impact Management LP | 770,289 | $24.4M | 2.80% | −19,409−2.5% | Reduced |
| Dimensional Fund Advisors LP | 827,139 | $26.3M | 0.01% | +148,832+21.9% | Added |
| Goldman Sachs Group Inc | 1,142,737 | $36.3M | 0.01% | −8,192−0.7% | Reduced |
| Geode Capital Management, LLC | 1,166,145 | $37.0M | 0.00% | +19,145+1.7% | Added |
| Point72 Asset Management, L.P. | 1,222,213 | $38.8M | 0.06% | −84,485−6.5% | Reduced |
| Assenagon Asset Management S.A. | 1,227,723 | $39.0M | 0.06% | +327,451+36.4% | Added |
| Polar Capital Holdings Plc | 1,269,131 | $40.3M | 0.18% | −54,339−4.1% | Reduced |
| Janus Henderson Group PLC | 1,450,933 | $46.0M | 0.02% | +1,116,452+333.8% | Added |
| Deerfield Management Company, L.P. (Series C) | 1,823,500 | $57.9M | 0.74% | +1,823,500 | New |
| Siren, L.L.C. | 2,247,347 | $71.3M | 2.13% | 00.0% | Unchanged |
| BVF Inc | 2,265,674 | $71.9M | 2.42% | +608,578+36.7% | Added |
| State Street Corp | 2,498,049 | $79.3M | 0.00% | +1,072,176+75.2% | Added |
| Vanguard Group Inc | 3,149,239 | $100.0M | 0.00% | −14,635−0.5% | Reduced |
| Toronto Dominion Bank | 3,173,258 | $100.7M | 0.18% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 3,336,697 | $105.9M | 0.62% | −1,297,141−28.0% | Reduced |
| Morgan Stanley | 3,546,158 | $112.6M | 0.01% | +9,108+0.3% | Added |
| Redmile Group, LLC | 4,034,070 | $128.0M | 9.43% | −141,472−3.4% | Reduced |
| BlackRock, Inc. | 5,212,554 | $165.4M | 0.00% | −774,887−12.9% | Reduced |
| Lynx1 Capital Management LP | 5,404,674 | $171.5M | 34.73% | 00.0% | Unchanged |
| RTW Investments, LP | 5,546,856 | $176.1M | 1.76% | +423,331+8.3% | Added |
| FMR LLC | 5,600,920 | $177.8M | 0.01% | −1,264,137−18.4% | Reduced |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −768,287−100.0% | Sold out |
| Checkpoint Capital L.P. | 0 | $0 | 0.00% | −212,049−100.0% | Sold out |
| Fort Point Capital Partners LLC | 0 | $0 | 0.00% | −75,429−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −61,048−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −24,340−100.0% | Sold out |
| Advantage Alpha Capital Partners LP | 0 | $0 | 0.00% | −16,941−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −12,100−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −9,358−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −956−100.0% | Sold out |
| Leonteq Securities AG | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Concord Wealth Partners | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Wealthspire Advisors, LLC | 0 | $0 | 0.00% | −50−100.0% | Sold out |
| Skorpios Trust | – | – | – | – | Not filed |