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Stoke Therapeutics, Inc.

STOK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001623526

In the last 90 days, Stoke Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 197 institutions reported holding it in 13F filings for Q2 2026, worth $2.49B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Stoke Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
134
+8 vs. Q1 2025
Shares held
65.5M
+2.16M (+3.4%) vs. Q1 2025
Total value
$744.0M
+$322.4M (+76.5%) vs. Q1 2025
New holders
24
51 more added
Sold out
16
33 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting STOK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 134 institutions
Q1 2021: 106 institutionsQ2 2021: 97 institutionsQ3 2021: 90 institutionsQ4 2021: 94 institutionsQ1 2022: 99 institutionsQ2 2022: 92 institutionsQ3 2022: 105 institutionsQ4 2022: 107 institutionsQ1 2023: 97 institutionsQ2 2023: 100 institutionsQ3 2023: 97 institutionsQ4 2023: 81 institutionsQ1 2024: 103 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 130 institutionsQ1 2025: 126 institutionsQ2 2025: 134 institutionsQ3 2025: 151 institutionsQ4 2025: 183 institutionsQ1 2026: 198 institutionsQ2 2026: 197 institutions
Value heldQ2 2025: $744.0M
Q1 2021: $1.49BQ2 2021: $680.3MQ3 2021: $492.4MQ4 2021: $849.6MQ1 2022: $870.6MQ2 2022: $569.4MQ3 2022: $544.4MQ4 2022: $371.8MQ1 2023: $371.8MQ2 2023: $494.8MQ3 2023: $173.1MQ4 2023: $236.9MQ1 2024: $731.7MQ2 2024: $828.5MQ3 2024: $715.5MQ4 2024: $640.4MQ1 2025: $421.6MQ2 2025: $744.0MQ3 2025: $1.57BQ4 2025: $2.13BQ1 2026: $2.31BQ2 2026: $2.49B
Institutions holding STOK and their total value by quarter
QuarterHoldersValue
Q2 2026197$2.49B
Q1 2026198$2.31B
Q4 2025183$2.13B
Q3 2025151$1.57B
Q2 2025134$744.0M
Q1 2025126$421.6M
Q4 2024130$640.4M
Q3 2024118$715.5M
Q2 2024115$828.5M
Q1 2024103$731.7M
Q4 202381$236.9M
Q3 202397$173.1M
Q2 2023100$494.8M
Q1 202397$371.8M
Q4 2022107$371.8M
Q3 2022105$544.4M
Q2 202292$569.4M
Q1 202299$870.6M
Q4 202194$849.6M
Q3 202190$492.4M
Q2 202197$680.3M
Q1 2021106$1.49B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Stoke Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding STOK in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Barclays PLC139,900$1.59M0.00%+71,539+104.6%Added
Royal Bank of Canada144,064$1.64M0.00%+144,016+300,033.3%Added
Schonfeld Strategic Advisors LLC174,714$1.98M0.01%−160,646−47.9%Reduced
Birchview Capital, LP210,000$2.38M2.37%−50.0%Reduced
Cormorant Asset Management, LP254,161$2.88M0.21%00.0%Unchanged
Charles Schwab Investment Management Inc340,779$3.87M0.00%+30,472+9.8%Added
UBS Group AG352,715$4.00M0.00%+180,884+105.3%Added
Erste Asset Management GmbH396,000$4.51M0.04%00.0%Unchanged
Northern Trust Corp423,554$4.81M0.00%+76,890+22.2%Added
Tang Capital Management LLC500,000$5.67M0.29%00.0%Unchanged
DAFNA Capital Management LLC501,972$5.70M1.57%+57,974+13.1%Added
Granahan Investment Management Inc532,413$6.04M0.25%−128,017−19.4%Reduced
Assenagon Asset Management S.A.537,973$6.11M0.01%−421,630−43.9%Reduced
Bank of America Corp548,090$6.22M0.00%+15,206+2.9%Added
Opaleye Management Inc.562,120$6.38M1.29%+262,120+87.4%Added
CI Private Wealth, LLC659,834$7.49M0.01%+659,834New
Dimensional Fund Advisors LP673,884$7.65M0.00%+9,149+1.4%Added
MPM Oncology Impact Management LP789,698$8.96M1.55%+95,710+13.8%Added
Polar Capital Holdings Plc883,646$10.0M0.05%+883,646New
Geode Capital Management, LLC972,921$11.0M0.00%+70,935+7.9%Added
Goldman Sachs Group Inc1,301,381$14.8M0.00%−360,658−21.7%Reduced
State Street Corp1,487,156$16.9M0.00%−88,127−5.6%Reduced
Siren, L.L.C.2,247,347$25.5M1.32%00.0%Unchanged
Marshall Wace, LLP2,300,554$26.1M0.03%+168,771+7.9%Added
Vanguard Group Inc2,946,258$33.4M0.00%+162,056+5.8%Added
Toronto Dominion Bank3,173,258$36.0M0.08%00.0%Unchanged
Skorpios Trust3,256,181$37.0M99.62%−3,650,000−52.9%Reduced
Morgan Stanley3,573,976$40.6M0.00%−16,849−0.5%Reduced
Redmile Group, LLC4,375,931$49.7M5.29%−110,050−2.5%Reduced
Baker Bros. Advisors LP4,633,838$52.6M0.51%00.0%Unchanged
RTW Investments, LP5,123,525$58.2M0.83%00.0%Unchanged
Lynx1 Capital Management LP5,404,674$61.3M17.72%+112,745+2.1%Added
BlackRock, Inc.5,924,567$67.2M0.00%+62,131+1.1%Added
FMR LLC7,412,982$84.1M0.00%+4,871,045+191.6%Added
Checkpoint Capital L.P.0$00.00%−730,717−100.0%Sold out
Renaissance Technologies LLC0$00.00%−178,300−100.0%Sold out
Trexquant Investment LP0$00.00%−86,140−100.0%Sold out
XTX Topco Ltd0$00.00%−40,181−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−36,087−100.0%Sold out
Dauntless Investment Group, LLC0$00.00%−28,600−100.0%Sold out
Net Worth Advisory Group0$00.00%−20,741−100.0%Sold out
Mesirow Financial Investment Management, Inc.0$00.00%−15,779−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−17,600−100.0%Sold out
Freestone Grove Partners LP0$00.00%−14,776−100.0%Sold out
Axq Capital, LP0$00.00%−14,600−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−13,780−100.0%Sold out
Covestor Ltd0$00.00%−2,417−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−55−100.0%Sold out
Parkside Financial Bank & Trust0$00.00%−50−100.0%Sold out
Parallel Advisors, LLC0$00.00%−24−100.0%Sold out