| Jul 6, 2026 (view filing)4:30 PM ET | Jul 1 | 5 days | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.05K | $53.88 | −$164.5K | −9.9%27.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 6, 2026 (view filing)4:30 PM ET | Jul 1 | 5 days | Gilman MichaelDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.54K | $53.87 | −$137.1K | −4.1%59.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 6, 2026 (view filing)4:30 PM ET | Jul 1 | 5 days | Burow KristinaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.05K | $53.74 | −$164.1K | −2.6%114.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 6, 2026 (view filing)4:30 PM ET | Jul 1 | 5 days | Reed JoshuaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.05K | $53.74 | −$164.1K | −13.5%19.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 6, 2026 (view filing)4:30 PM ET | Jul 1 | 5 days | Peng KatieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.45K | $53.88 | −$293.4K | −13.7%34.3K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 20, 2026 (view filing) | Apr 16 | 4 days | Woods KeithChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.2K | $49.57 | −$506.6K | −1.6%620.1K after | |
| Apr 20, 2026 (view filing) | Apr 16 | 4 days | Vaishnaw AkshayPresident of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.2K | $49.57 | −$607.0K | −1.9%630.5K after | |
| Apr 20, 2026 (view filing) | Apr 16 | 4 days | Sinha VikasChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.4K | $49.57 | −$516.0K | −1.7%619.9K after | |
| Apr 20, 2026 (view filing) | Apr 16 | 4 days | Hallal DavidChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.6K | $49.57 | −$1.52M | −1.8%1.64M after | |
| Feb 25, 2026 (view filing) | Feb 23 | 2 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.48K | $47.07 | −$399.3K | −7.9%98.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2026 (view filing) | Feb 17 | 2 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.99K | $46.53 | −$371.7K | −7.0%106.9K after | |
| Feb 19, 2026 (view filing) | Feb 17 | 2 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.04K | $46.53 | −$420.4K | −5.1%169.1K after | |
| Feb 19, 2026 (view filing) | Feb 17 | 2 days | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.58K | $46.53 | −$445.8K | −3.8%241.5K after | |
| Feb 19, 2026 (view filing) | Feb 17 | 2 days | Marantz Jing L.CHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.16K | $46.53 | −$193.4K | −3.2%126.0K after | |
| Jan 23, 2026 (view filing) | Jan 22 | 1 day | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.9K | $46.71 | −$695.9K | −14.8%85.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 21, 2026 (view filing) | Jan 16 | 5 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.41K | $44.48 | −$373.9K | −7.7%100.6K after | |
| Jan 21, 2026 (view filing) | Jan 16 | 5 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.60K | $44.48 | −$293.6K | −4.2%148.9K after | |
| Jan 21, 2026 (view filing) | Jan 16 | 5 days | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.02K | $44.48 | −$356.6K | −3.6%214.6K after | |
| Jan 21, 2026 (view filing) | Jan 16 | 5 days | Marantz Jing L.CHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.80K | $44.48 | −$257.9K | −5.7%95.7K after | |
| Jan 16, 2026 (view filing) | Jan 14 | 2 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.1K | $45.20 | −$592.7K | −10.7%109.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 15, 2026 (view filing) | Jan 13 | 2 days | Sinha VikasChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.8K | $42.70 | −$715.4K | −2.8%583.2K after | |
| Jan 15, 2026 (view filing) | Jan 13 | 2 days | Woods KeithChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.7K | $42.70 | −$715.1K | −2.8%583.3K after | |
| Jan 15, 2026 (view filing) | Jan 13 | 2 days | Vaishnaw AkshayPresident of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.4K | $42.70 | −$872.7K | −3.3%595.8K after | |
| Jan 15, 2026 (view filing) | Jan 13 | 2 days | Hallal DavidChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −57.5K | $42.70 | −$2.45M | −3.6%1.54M after | |
| Dec 18, 2025 (view filing) | Dec 16 | 2 days | Peng KatieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.01K | $44.09 | −$44.4K | −3.0%32.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 16, 2025 (view filing) | Oct 7 | 70 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Akkaraju SrinivasDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +29.6K | $39.92 | +$1.18M | +5.9%530.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 5, 2025 (view filing) | Dec 4 | 1 day | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −136.5K | $45.21 | −$6.17M | −55.6%109.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 7, 2025 (view filing) | Oct 3-6 | 4 days | Akkaraju SrinivasDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +500.4K | $37.58 | +$18.8M | New position500.4K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 24, 2025 (view filing) | Sep 22 | 2 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.35K | $30.67 | −$102.8K | −3.0%109.0K after | |
| Sep 17, 2025 (view filing) | Sep 16 | 1 day | Peng KatieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.01K | $32.53 | −$32.7K | −2.9%33.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2025 (view filing) | Sep 16 | 1 day | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.18K | $33.52 | −$106.5K | −2.8%112.3K after | |
| Aug 19, 2025 (view filing) | Aug 18 | 1 day | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.18K | $31.17 | −$67.9K | −1.4%155.5K after | |
| Jul 18, 2025 (view filing) | Jul 16 | 2 days | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.1K | $40.02 | −$445.7K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 10, 2025 (view filing) | Jul 8 | 2 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.1K | $34.44 | −$828.8K | −17.2%115.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 25, 2025 (view filing) | Jun 23 | 2 days | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.3K | $32.24 | −$655.0K | −45.8%24.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 25, 2025 (view filing) | Jun 23 | 2 days | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.1K | $33.21 | −$369.8K | −50.0%11.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 17, 2025 (view filing) | Jun 16 | 1 day | Peng KatieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.03K | $31.97 | −$96.9K | −8.0%34.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 17, 2025 (view filing) | Jun 16 | 1 day | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.67K | $32.00 | −$117.4K | −2.6%139.6K after | |
| Jun 17, 2025 (view filing) | Jun 16 | 1 day | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.19K | $32.00 | −$198.0K | −3.8%157.6K after | |
| Jun 17, 2025 (view filing) | Jun 16 | 1 day | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.44K | $32.00 | −$238.1K | −3.2%222.6K after | |
| May 30, 2025 (view filing) | May 29 | 1 day | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.08K | $29.73 | −$180.6K | −20.2%24.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2025 (view filing) | May 29 | 1 day | Burow KristinaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.40K | $29.72 | −$160.5K | −20.4%21.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2025 (view filing) | May 29 | 1 day | Gilman MichaelDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.38K | $29.72 | −$100.3K | −5.8%55.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2025 (view filing) | May 29 | 1 day | Brudnick RichardDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.08K | $29.72 | −$180.5K | −28.7%15.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2025 (view filing) | May 29 | 1 day | Reed JoshuaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.40K | $29.71 | −$160.5K | −25.6%15.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2025 (view filing) | May 29 | 1 day | Vaishnaw AkshayPresident of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.75K | $29.72 | −$200.6K | −1.1%616.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 29, 2025 (view filing) | Apr 25 | 4 days | Sacco TraceyChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $32.82 | −$164.1K | −6.5%71.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 25, 2025 (view filing) | Mar 24 | 1 day | Sacco TraceyChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.50K | $33.08 | −$215.0K | −8.3%71.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 25, 2025 (view filing) | Mar 24 | 1 day | Moore ErinInterim PFO and PAO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.6K | $33.12 | −$449.2K | −14.1%82.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 19, 2025 (view filing) | Mar 17 | 2 days | Peng KatieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.01K | $34.42 | −$34.6K | −3.2%30.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
