| Jul 28, 2021 (view filing) | Jul 26 | 2 days | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.00K | $31.66 | −$189.9K | −17.5%28.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 21, 2021 (view filing) | Sep 20 | 1 day | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −500 | $34.09 | −$17.0K | −5.3%9.01K after | |
| Oct 5, 2021 (view filing) | Oct 1 | 4 days | Flier Jeffrey S.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.00K | $30.89 | −$185.3K | −21.2%22.3K after | |
| Nov 15, 2021 (view filing) | Nov 11-15 | 4 days | Myles Edward HChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −78.3K | $35.14 | −$2.75M | −76.4%24.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 24, 2022 (view filing) | Jun 22 | 2 days | Nashat AmirDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.20M | $4.90 | +$5.87M | New position206.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 24, 2022 (view filing) | Jun 22 | 2 days | Nashat AmirDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +299.5K | $4.90 | +$1.47M | –16.5K after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 7, 2022 (view filing)4:30 PM ET | Oct 3-4 | 4 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Artal Group S.A. and 7 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +100.0K | $7.60 | +$759.5K | +1.1%8.85M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 27, 2022 (view filing)4:36 PM ET | Oct 25 | 2 days | Artal Group S.A. and 7 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +130.3K | $8.04 | +$1.05M | +1.5%8.98M after | |
| Jan 9, 2023 (view filing)5:22 PM ET | Jan 5 | 4 days | Artal Group S.A. and 7 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +48.8K | $9.33 | +$455.1K | +0.5%9.03M after | |
| Jan 11, 2023 (view filing)8:30 PM ET | Jan 9 | 2 days | Artal Group S.A. and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.09K | $9.48 | −$10.4K | 0.0%9.03M after | |
| May 2, 2023 (view filing)9:00 PM ET | Apr 28 | 4 days | Artal Group S.A. and 7 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +31.6K | $6.43 | +$202.8K | +0.3%9.06M after | |
| Aug 18, 2023 (view filing) | Aug 16 | 2 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.35K | $6.83 | −$9.24K | −1.1%117.2K after | |
| Sep 20, 2023 (view filing) | Sep 18 | 2 days | Qatanani MoSVP AND HEAD OF RESEARCH | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.95K | $6.34 | −$12.3K | −2.0%97.0K after | |
| Oct 16, 2023 (view filing)5:46 PM ET | Oct 12 | 4 days | Artal Group S.A. and 7 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.20M | $6.86 | +$15.1M | +24.3%11.3M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 18, 2023 (view filing) | Oct 16 | 2 days | Akkaraju SrinivasDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.19M | $6.85 | +$15.0M | +47.6%6.79M after | |
| Oct 18, 2023 (view filing)5:44 PM ET | Oct 16 | 2 days | Samsara BioCapital, L.P. and 1 other10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.19M | $6.85 | +$15.0M | +47.6%6.79M after | Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Nov 3, 2023 (view filing) | Nov 2 | 1 day | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −35.0K | $12.51 | −$437.9K | −17.2%168.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 8, 2023 (view filing) | Dec 7 | 1 day | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.9K | $17.53 | −$436.7K | −12.9%168.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 15, 2023 (view filing) | Dec 14 | 1 day | Qatanani MoSVP AND HEAD OF RESEARCH | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.7K | $18.18 | −$448.4K | −23.4%80.8K after | |
| Dec 29, 2023 (view filing) | Dec 29 | Same day | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.5K | $18.84 | −$234.7K | −6.9%168.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 18, 2024 (view filing) | Jan 16 | 2 days | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.19K | $15.93 | −$66.7K | −2.6%154.4K after | |
| Jan 18, 2024 (view filing) | Jan 16 | 2 days | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.63K | $15.93 | −$105.7K | −3.9%162.2K after | |
| Jan 18, 2024 (view filing) | Jan 16 | 2 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.85K | $15.93 | −$45.4K | −2.4%114.3K after | |
| Jan 18, 2024 (view filing) | Jan 16 | 2 days | Qatanani MoSVP AND HEAD OF RESEARCH | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $15.93 | −$31.9K | −2.5%78.8K after | |
| Feb 20, 2024 (view filing) | Feb 16 | 4 days | Backstrom Jay T.CHIEF EXECUTIVE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.6K | $15.74 | −$182.8K | −3.2%352.7K after | |
| Feb 20, 2024 (view filing) | Feb 16 | 4 days | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.49K | $15.74 | −$54.9K | −1.6%208.8K after | |
| Feb 20, 2024 (view filing) | Feb 16 | 4 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.75K | $15.74 | −$59.0K | −2.3%157.7K after | |
| Feb 20, 2024 (view filing) | Feb 16 | 4 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.51K | $15.74 | −$39.5K | −1.7%147.0K after | |
| Feb 21, 2024 (view filing) | Feb 16 | 5 days | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.74K | $15.74 | −$74.7K | −2.2%211.0K after | |
| Jun 18, 2024 (view filing) | Jun 17 | 1 day | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.70K | $8.98 | −$42.2K | −2.2%204.1K after | |
| Jun 18, 2024 (view filing) | Jun 17 | 1 day | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.46K | $8.98 | −$84.9K | −4.5%201.5K after | |
| Jun 18, 2024 (view filing) | Jun 17 | 1 day | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.30K | $8.98 | −$38.7K | −2.7%153.4K after | |
| Jun 18, 2024 (view filing) | Jun 17 | 1 day | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.31K | $8.99 | −$20.8K | −1.6%144.7K after | |
| Aug 19, 2024 (view filing) | Aug 16 | 3 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.45K | $9.33 | −$13.5K | −0.9%152.0K after | |
| Sep 19, 2024 (view filing) | Sep 16 | 3 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.94K | $8.58 | −$16.6K | −1.3%142.8K after | |
| Oct 7, 2024 (view filing) | Oct 7 | Same day | Marantz Jing L.CHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −109.4K | $27.21 | −$2.98M | −60.0%72.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 7, 2024 (view filing) | Oct 7 | Same day | Sacco TraceyCHIEF COMMERCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.0K | $25.62 | −$768.7K | −37.8%49.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 7, 2024 (view filing) | Oct 7 | Same day | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −206.2K | $26.56 | −$5.48M | −56.1%161.1K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 7, 2024 (view filing) | Oct 7 | Same day | Akkaraju SrinivasDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.18M | $29.25 | −$34.4M | −17.3%5.61M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 10, 2024 (view filing) | Oct 8 | 2 days | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −37.2K | $34.90 | −$1.30M | −18.8%161.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 13, 2024 (view filing) | Nov 11 | 2 days | Marantz Jing L.CHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.10K | $30.00 | −$63.1K | −2.8%72.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 26, 2024 (view filing) | Nov 22-25 | 4 days | Marantz Jing L.CHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.52K | $37.06 | −$315.8K | −10.5%72.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 27, 2024 (view filing)4:31 PM ET | Nov 25 | 2 days | Debbane Raymond and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −409.4K | $38.49 | −$15.8M | −3.6%10.9M after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 12, 2024 (view filing)4:39 PM ET | Dec 10 | 2 days | Debbane Raymond and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.60M | $41.65 | −$66.6M | −14.7%9.25M after | |
| Jan 21, 2025 (view filing) | Jan 16 | 5 days | Ho JunlinGENERAL COUNSEL | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.04K | $44.20 | −$399.5K | −4.4%195.0K after | |
| Jan 21, 2025 (view filing) | Jan 16 | 5 days | Myles Edward HCOO & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.5K | $44.20 | −$554.2K | −7.8%148.5K after | |
| Jan 21, 2025 (view filing) | Jan 16 | 5 days | Parlavecchio CarynCHRO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.43K | $44.20 | −$284.4K | −4.2%145.6K after | |
| Jan 21, 2025 (view filing) | Jan 16 | 5 days | Qatanani MoCHIEF SCIENTIFIC OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.35K | $44.20 | −$324.7K | −5.1%135.4K after | |
| Jan 21, 2025 (view filing) | Jan 16 | 5 days | Sacco TraceyChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.89K | $44.20 | −$171.9K | −7.9%45.4K after | |
| Jan 21, 2025 (view filing) | Jan 16 | 5 days | Marantz Jing L.CHIEF MEDICAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.66K | $44.20 | −$250.0K | −7.8%67.2K after | |
