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Seaport Therapeutics, Inc.

SPTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002042347

No open-market purchases or sales by Seaport Therapeutics, Inc. insiders were filed in the last 90 days; 54 institutions reported holding it in 13F filings for Q2 2026, worth $815.3M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Seaport Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
54
+54 vs. Q1 2026
Shares held
37.5M
+37.5M vs. Q1 2026
Total value
$815.3M
+$815.3M vs. Q1 2026
New holders
54
0 more added
Sold out
0
0 more reduced

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SPTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 54 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 54 institutions
Value heldQ2 2026: $815.3M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $815.3M
Institutions holding SPTX and their total value by quarter
QuarterHoldersValue
Q2 202654$815.3M
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Seaport Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding SPTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
ARCH Venture Management, LLC6,294,951$136.6M12.42%+6,294,951New
General Atlantic LLC6,101,582$132.5M4.56%+6,101,582New
Sofinnova Investments, Inc.3,564,871$77.4M4.14%+3,564,871New
Goldman Sachs Group Inc2,178,642$47.3M0.00%+2,178,642New
TRV GP VI, LLC2,061,222$44.8M19.27%+2,061,222New
Canada Pension Plan Investment Board1,975,791$42.9M0.02%+1,975,791New
JPMorgan Chase & Co1,815,845$40.9M0.00%+1,815,845New
Foresite Capital Management VI LLC1,779,521$38.7M6.02%+1,779,521New
Price T Rowe Associates Inc1,308,604$28.4M0.00%+1,308,604New
FMR LLC1,185,100$25.7M0.00%+1,185,100New
Bellevue Group AG1,100,000$23.9M0.50%+1,100,000New
Siren, L.L.C.1,095,316$23.8M0.48%+1,095,316New
Jennison Associates LLC1,079,669$23.5M0.01%+1,079,669New
Ra Capital Management, L.P.700,000$15.2M0.13%+700,000New
Vanguard Capital Management LLC599,217$13.0M0.00%+599,217New
Woodline Partners LP586,345$12.7M0.04%+586,345New
Perceptive Advisors LLC500,000$10.9M0.17%+500,000New
Braidwell LP500,000$10.9M0.40%+500,000New
Principal Financial Group Inc414,672$9.01M0.00%+414,672New
Standard Life Aberdeen plc310,355$6.74M0.01%+310,355New
UBS Group AG279,184$6.06M0.00%+279,184New
BlackRock, Inc.229,863$4.99M0.00%+229,863New
Seven Grand Managers, LLC225,000$4.89M0.20%+225,000New
Citadel Advisors LLC191,144$4.15M0.00%+191,144New
Geode Capital Management, LLC175,866$3.82M0.00%+175,866New
Pier Capital, LLC169,985$3.69M0.49%+169,985New
Ameriprise Financial Inc131,788$2.86M0.00%+131,788New
Charles Schwab Investment Management Inc97,693$2.12M0.00%+97,693New
Vanguard Fiduciary Trust Co87,772$1.91M0.00%+87,772New
Pentwater Capital Management LP83,000$1.80M0.01%+83,000New
Manufacturers Life Insurance Company, The82,565$1.79M0.00%+82,565New
Alyeska Investment Group, L.P.75,000$1.63M0.00%+75,000New
State Street Corp66,650$1.45M0.00%+66,650New
Alps Advisors Inc54,328$1.18M0.01%+54,328New
TD Asset Management Inc47,944$1.04M0.00%+47,944New
Millennium Management LLC45,337$984.7K0.00%+45,337New
Gsa Capital Partners LLP33,178$721.0K0.05%+33,178New
DAFNA Capital Management LLC32,400$703.7K0.13%+32,400New
Northern Trust Corp31,802$690.7K0.00%+31,802New
ADAR1 Capital Management, LLC26,000$564.7K0.03%+26,000New
Ghisallo Capital Management LLC25,000$543.0K0.01%+25,000New
Burkehill Global Management, LP25,000$543.0K0.02%+25,000New
Squarepoint Ops LLC24,753$537.6K0.00%+24,753New
HighTower Advisors, LLC16,666$362.0K0.00%+16,666New
Morgan Stanley11,692$254.0K0.00%+11,692New
XTX Topco Ltd10,983$238.6K0.00%+10,983New
Weiss Asset Management LP10,000$217.2K0.00%+10,000New
Zimmer Partners, LP10,000$217.2K0.01%+10,000New
Vanguard Portfolio Management LLC9,081$197.2K0.00%+9,081New
Vanguard Global Advisers, LLC7,159$155.5K0.00%+7,159New
Citigroup Inc2,454$53.3K0.00%+2,454New
Jones Financial Companies LLLP2,256$48.3K0.00%+2,256New
Assetmark, Inc1,431$31.1K0.00%+1,431New
Barclays PLC837$18.2K0.00%+837New