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Summit Therapeutics Inc.

SMMT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001599298

No open-market purchases or sales by Summit Therapeutics Inc. insiders were filed in the last 90 days; 242 institutions reported holding it in 13F filings for Q2 2026, worth $1.98B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Summit Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
206
−25 vs. Q3 2025
Shares held
117.8M
+14.9M (+14.5%) vs. Q3 2025
Total value
$2.06B
−$66.0M (−3.1%) vs. Q3 2025
New holders
35
75 more added
Sold out
60
65 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SMMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 206 institutions
Q1 2021: 38 institutionsQ2 2021: 54 institutionsQ3 2021: 51 institutionsQ4 2021: 52 institutionsQ1 2022: 48 institutionsQ2 2022: 41 institutionsQ3 2022: 42 institutionsQ4 2022: 57 institutionsQ1 2023: 86 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 95 institutionsQ1 2024: 103 institutionsQ2 2024: 121 institutionsQ3 2024: 164 institutionsQ4 2024: 196 institutionsQ1 2025: 202 institutionsQ2 2025: 226 institutionsQ3 2025: 232 institutionsQ4 2025: 206 institutionsQ1 2026: 222 institutionsQ2 2026: 242 institutions
Value heldQ4 2025: $2.06B
Q1 2021: $54.5MQ2 2021: $82.4MQ3 2021: $55.3MQ4 2021: $30.0MQ1 2022: $27.4MQ2 2022: $8.46MQ3 2022: $3.78MQ4 2022: $34.5MQ1 2023: $37.0MQ2 2023: $87.6MQ3 2023: $60.4MQ4 2023: $84.4MQ1 2024: $205.5MQ2 2024: $563.0MQ3 2024: $1.85BQ4 2024: $1.65BQ1 2025: $1.91BQ2 2025: $2.08BQ3 2025: $2.13BQ4 2025: $2.06BQ1 2026: $2.25BQ2 2026: $1.98B
Institutions holding SMMT and their total value by quarter
QuarterHoldersValue
Q2 2026242$1.98B
Q1 2026222$2.25B
Q4 2025206$2.06B
Q3 2025232$2.13B
Q2 2025226$2.08B
Q1 2025202$1.91B
Q4 2024196$1.65B
Q3 2024164$1.85B
Q2 2024121$563.0M
Q1 2024103$205.5M
Q4 202395$84.4M
Q3 202391$60.4M
Q2 202396$87.6M
Q1 202386$37.0M
Q4 202257$34.5M
Q3 202242$3.78M
Q2 202241$8.46M
Q1 202248$27.4M
Q4 202152$30.0M
Q3 202151$55.3M
Q2 202154$82.4M
Q1 202138$54.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Summit Therapeutics Inc.; share changes are against Q3 2025.

Institutions holding SMMT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
State Street Corp6,636,361$116.1M0.00%+274,425+4.3%Added
BlackRock, Inc.9,361,921$163.7M0.00%+1,998,128+27.1%Added
Price T Rowe Associates Inc9,371,415$163.9M0.02%+4,832,592+106.5%Added
Vanguard Group Inc11,177,220$195.5M0.00%−202,508−1.8%Reduced
FMR LLC13,360,807$233.7M0.01%+4,442,920+49.8%Added
Baker Bros. Advisors LP36,391,063$636.5M3.73%+2,668,089+7.9%Added
Fiera Capital Corp0$00.00%−762,094−100.0%Sold out
Polar Capital Holdings Plc0$00.00%−746,393−100.0%Sold out
Tang Capital Management LLC0$00.00%−550,000−100.0%Sold out
Capricorn Fund Managers Ltd0$00.00%−496,266−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−246,562−100.0%Sold out
Superstring Capital Management LP0$00.00%−197,253−100.0%Sold out
Yong Rong (HK) Asset Management Ltd0$00.00%−100,000−100.0%Sold out
HealthInvest Partners AB0$00.00%−92,737−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−92,538−100.0%Sold out
Winton Group Ltd0$00.00%−64,900−100.0%Sold out
Perseverance Asset Management International0$00.00%−59,745−100.0%Sold out
Verde Servicos Internacionais S.A.0$00.00%−40,000−100.0%Sold out
Man Group plc0$00.00%−29,550−100.0%Sold out
Caption Management, LLC0$00.00%−28,264−100.0%Sold out
Stifel Financial Corp0$00.00%−26,832−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−23,513−100.0%Sold out
Quantbot Technologies LP0$00.00%−23,381−100.0%Sold out
Brinker Capital Investments, LLC0$00.00%−20,278−100.0%Sold out
World Equity Group, Inc.0$00.00%−18,854−100.0%Sold out
Calamos Advisors LLC0$00.00%−18,628−100.0%Sold out
Skopos Labs, Inc.0$00.00%−16,300−100.0%Sold out
Snowden Capital Advisors LLC0$00.00%−15,192−100.0%Sold out
Amundi0$00.00%−13,999−100.0%Sold out
XTX Topco Ltd0$00.00%−14,535−100.0%Sold out
JGP Global Gestao de Recursos Ltda.0$00.00%−12,868−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−11,909−100.0%Sold out
Quadrature Capital Ltd0$00.00%−11,721−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−11,351−100.0%Sold out
New York Life Investment Management LLC0$00.00%−11,048−100.0%Sold out
HighTower Advisors, LLC0$00.00%−10,758−100.0%Sold out
Avanza Fonder AB0$00.00%−4,487−100.0%Sold out
Crowley Wealth Management, Inc.0$00.00%−1,500−100.0%Sold out
Tortoise Investment Management, LLC0$00.00%−1,468−100.0%Sold out
Ball & Co Wealth Management Inc.0$00.00%−1,500−100.0%Sold out
Harvest Fund Management Co., Ltd0$00.00%−1,145−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−867−100.0%Sold out
Principal Securities, Inc.0$00.00%−708−100.0%Sold out
Contravisory Investment Management, Inc.0$00.00%−600−100.0%Sold out
Spire Wealth Management0$00.00%−525−100.0%Sold out
Bradley & Co. Private Wealth Management, LLC0$00.00%−200−100.0%Sold out
Ci Investments Inc.0$00.00%−181−100.0%Sold out
Roxbury Financial LLC0$00.00%−187−100.0%Sold out
Bell Investment Advisors, Inc0$00.00%−136−100.0%Sold out
Bokf, NA0$00.00%−100−100.0%Sold out
Groupe la Francaise0$00.00%−110−100.0%Sold out
Park Place Capital Corp0$00.00%−62−100.0%Sold out
Cape Investment Advisory, Inc.0$00.00%−60−100.0%Sold out
Whittier Trust Co of Nevada Inc0$00.00%−57−100.0%Sold out
Quent Capital, LLC0$00.00%−51−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−33−100.0%Sold out
Rise Advisors, LLC0$00.00%−28−100.0%Sold out
Fortitude Family Office, LLC0$00.00%−28−100.0%Sold out
DiNuzzo Private Wealth, Inc.0$00.00%−18−100.0%Sold out
Parkside Financial Bank & Trust0$00.00%−18−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−10−100.0%Sold out
MV Capital Management, Inc.0$00.00%−6−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−2−100.0%Sold out
Optiver Holding B.V.0$00.00%−2−100.0%Sold out
HFM Investment Advisors, LLC0$00.00%−2−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−3−100.0%Sold out
Hemington Wealth Management––––Not filed