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Summit Therapeutics Inc.

SMMT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001599298

No open-market purchases or sales by Summit Therapeutics Inc. insiders were filed in the last 90 days; 242 institutions reported holding it in 13F filings for Q2 2026, worth $1.98B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Summit Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
206
−25 vs. Q3 2025
Shares held
117.8M
+14.9M (+14.5%) vs. Q3 2025
Total value
$2.06B
−$66.0M (−3.1%) vs. Q3 2025
New holders
35
75 more added
Sold out
60
65 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SMMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 206 institutions
Q1 2021: 38 institutionsQ2 2021: 54 institutionsQ3 2021: 51 institutionsQ4 2021: 52 institutionsQ1 2022: 48 institutionsQ2 2022: 41 institutionsQ3 2022: 42 institutionsQ4 2022: 57 institutionsQ1 2023: 86 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 95 institutionsQ1 2024: 103 institutionsQ2 2024: 121 institutionsQ3 2024: 164 institutionsQ4 2024: 196 institutionsQ1 2025: 202 institutionsQ2 2025: 226 institutionsQ3 2025: 232 institutionsQ4 2025: 206 institutionsQ1 2026: 222 institutionsQ2 2026: 242 institutions
Value heldQ4 2025: $2.06B
Q1 2021: $54.5MQ2 2021: $82.4MQ3 2021: $55.3MQ4 2021: $30.0MQ1 2022: $27.4MQ2 2022: $8.46MQ3 2022: $3.78MQ4 2022: $34.5MQ1 2023: $37.0MQ2 2023: $87.6MQ3 2023: $60.4MQ4 2023: $84.4MQ1 2024: $205.5MQ2 2024: $563.0MQ3 2024: $1.85BQ4 2024: $1.65BQ1 2025: $1.91BQ2 2025: $2.08BQ3 2025: $2.13BQ4 2025: $2.06BQ1 2026: $2.25BQ2 2026: $1.98B
Institutions holding SMMT and their total value by quarter
QuarterHoldersValue
Q2 2026242$1.98B
Q1 2026222$2.25B
Q4 2025206$2.06B
Q3 2025232$2.13B
Q2 2025226$2.08B
Q1 2025202$1.91B
Q4 2024196$1.65B
Q3 2024164$1.85B
Q2 2024121$563.0M
Q1 2024103$205.5M
Q4 202395$84.4M
Q3 202391$60.4M
Q2 202396$87.6M
Q1 202386$37.0M
Q4 202257$34.5M
Q3 202242$3.78M
Q2 202241$8.46M
Q1 202248$27.4M
Q4 202152$30.0M
Q3 202151$55.3M
Q2 202154$82.4M
Q1 202138$54.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Summit Therapeutics Inc.; share changes are against Q3 2025.

Institutions holding SMMT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Alliancebernstein L.P.20,606$360.4K0.00%+383+1.9%Added
Cynosure Management, LLC22,070$386.0K0.04%+3,461+18.6%Added
Allianz Asset Management GmbH22,200$388.3K0.00%00.0%Unchanged
Wealth Enhancement Advisory Services, LLC20,875$389.5K0.00%+4,464+27.2%Added
Steward Partners Investment Advisory, LLC23,045$403.1K0.00%+3,133+15.7%Added
CIBC Asset Management Inc24,289$424.8K0.00%+2,166+9.8%Added
Entropy Technologies, LP25,162$440.1K0.02%+25,162New
Great Valley Advisor Group, Inc.25,640$448.4K0.01%−33−0.1%Reduced
Eurizon Capital SGR S.p.A.25,662$448.8K0.00%+25,662New
Schonfeld Strategic Advisors LLC27,304$477.5K0.00%+27,304New
Legal & General Group Plc27,359$478.5K0.00%+823+3.1%Added
First Trust Advisors LP28,115$491.7K0.00%−143,409−83.6%Reduced
Capstone Capital Management Ltd28,190$493.0K0.47%+28,190New
IMC-Chicago, LLC29,704$519.5K0.01%+29,704New
Group One Trading, L.P.31,410$549.4K0.02%+1,160+3.8%Added
ProShare Advisors LLC32,881$575.1K0.00%+6,418+24.3%Added
Public Employees Retirement System of Ohio35,158$614.9K0.00%−1,334−3.7%Reduced
Vident Advisory, LLC35,880$627.5K0.01%−766−2.1%Reduced
BNP Paribas Arbitrage, SA37,084$648.6K0.00%+7,908+27.1%Added
Handelsbanken Fonder AB37,600$658.0K0.00%+3,400+9.9%Added
Levin Capital Strategies, L.P.37,676$659.0K0.06%+1,000+2.7%Added
Mirae Asset Global Investments Co., Ltd.37,991$664.5K0.00%+7,403+24.2%Added
Beacon Pointe Advisors, LLC39,611$692.8K0.00%+3,885+10.9%Added
Worldquant Millennium Advisors LLC41,734$729.9K0.00%+41,734New
Treasurer of the State of North Carolina48,940$856.0K0.00%−3,579−6.8%Reduced
Guggenheim Capital LLC49,798$871.0K0.01%+8,801+21.5%Added
Balyasny Asset Management LLC50,298$879.7K0.00%−144,553−74.2%Reduced
Police & Firemen's Retirement System of New Jersey52,619$920.3K0.01%+114+0.2%Added
New York State Common Retirement Fund53,777$940.6K0.00%−210,513−79.7%Reduced
Ameriprise Financial Inc54,012$944.7K0.00%+500+0.9%Added
Farther Finance Advisors, LLC57,282$1.00M0.01%+2,046+3.7%Added
Wealth Management Partners, LLC59,430$1.04M0.30%−15,140−20.3%Reduced
Assenagon Asset Management S.A.59,621$1.04M0.00%+59,621New
Aquatic Capital Management LLC59,945$1.05M0.03%+59,945New
DnB Asset Management AS61,061$1.07M0.00%+30,138+97.5%Added
JPMorgan Chase & Co67,422$1.18M0.00%−69,204−50.7%Reduced
Mariner, LLC73,497$1.29M0.00%−6,075−7.6%Reduced
Polianta Ltd74,700$1.31M0.17%00.0%Unchanged
LMR Partners LLP75,200$1.32M0.01%+75,200New
Sectoral Asset Management Inc79,625$1.39M1.12%+5,555+7.5%Added
UBS Asset Management Americas Inc79,626$1.39M0.00%+370.0%Added
Axq Capital, LP81,519$1.43M0.32%+64,051+366.7%Added
Dark Forest Capital Management LP87,069$1.52M0.07%−25,130−22.4%Reduced
Colony Group, LLC88,448$1.55M0.00%+290.0%Added
ADAR1 Capital Management, LLC91,869$1.61M0.12%−11,100−10.8%Reduced
State of Wisconsin Investment Board92,882$1.62M0.00%+1,047+1.1%Added
Bank of Montreal95,371$1.67M0.00%−2,647−2.7%Reduced
Tema ETFs LLC95,782$1.68M0.13%+15,498+19.3%Added
State Board of Administration of Florida Retirement System96,009$1.68M0.00%00.0%Unchanged
NEOS Investment Management LLC97,217$1.70M0.01%+16,933+21.1%Added
HSBC Holdings PLC98,766$1.72M0.00%+98,766New
Illinois Municipal Retirement Fund99,367$1.74M0.02%+30,694+44.7%Added
Jefferies Financial Group Inc.100,000$1.75M0.01%+85,000+566.7%Added
Profund Advisors LLC103,761$1.81M0.06%+33,828+48.4%Added
Voya Investment Management LLC112,437$1.97M0.00%−90,181−44.5%Reduced
Cerity Partners LLC112,878$1.97M0.00%−1,779−1.6%Reduced
Capital Fund Management S.A.113,391$1.98M0.02%+39,238+52.9%Added
China Universal Asset Management Co., Ltd.121,307$2.12M0.16%−8,903−6.8%Reduced
Rhumbline Advisers121,341$2.12M0.00%−1,581−1.3%Reduced
Citigroup Inc129,926$2.27M0.00%−29,947−18.7%Reduced
Wells Fargo & Company130,886$2.29M0.00%−61,990−32.1%Reduced
Griffin Asset Management, Inc.195,547$3.42M0.37%+55,265+39.4%Added
Woodline Partners LP214,507$3.75M0.01%00.0%Unchanged
Verition Fund Management LLC228,990$4.01M0.02%+63,388+38.3%Added
Nuveen, LLC232,642$4.07M0.00%00.0%Unchanged
Deutsche Bank AG237,788$4.16M0.00%−32,096−11.9%Reduced
Schroder Investment Management Group251,391$4.40M0.00%+8,772+3.6%Added
Rafferty Asset Management, LLC287,810$5.03M0.02%−51,366−15.1%Reduced
Readystate Asset Management LP306,184$5.36M0.24%+306,184New
Skandinaviska Enskilda Banken AB (publ)338,363$5.91M0.02%00.0%Unchanged
Barclays PLC338,390$5.92M0.00%−137,387−28.9%Reduced
Bank of New York Mellon Corp353,756$6.19M0.00%−13,370−3.6%Reduced
AQR Capital Management LLC357,870$6.19M0.00%+170,386+90.9%Added
Sculptor Capital LP356,900$6.24M0.07%+23,400+7.0%Added
QVT Financial LP360,524$6.31M0.60%00.0%Unchanged
Dimensional Fund Advisors LP376,563$6.59M0.00%+1,980+0.5%Added
D. E. Shaw & Co., Inc.415,284$7.26M0.01%+284,657+217.9%Added
Tudor Investment Corp Et Al423,084$7.40M0.04%+75,843+21.8%Added
Manufacturers Life Insurance Company, The440,953$7.71M0.01%+141,407+47.2%Added
Invesco Ltd.461,301$8.07M0.00%+35,226+8.3%Added
Millennium Management LLC469,017$8.20M0.01%+348,503+289.2%Added
Bank of America Corp477,393$8.35M0.00%−179,920−27.4%Reduced
Goldman Sachs Group Inc485,566$8.49M0.00%−11,981−2.4%Reduced
Northern Trust Corp528,487$9.24M0.00%−17,775−3.3%Reduced
Candriam Luxembourg S.C.A.540,662$9.46M0.05%+26,899+5.2%Added
Nomura Holdings Inc542,234$9.48M0.03%−506,693−48.3%Reduced
Two Sigma Investments, LP578,248$10.1M0.02%+553,218+2,210.2%Added
Rock Springs Capital Management LP710,000$12.4M0.64%00.0%Unchanged
Squarepoint Ops LLC715,410$12.5M0.03%+605,584+551.4%Added
UBS Group AG870,719$15.2M0.00%−408,064−31.9%Reduced
Charles Schwab Investment Management Inc892,629$15.6M0.00%+16,239+1.9%Added
Morgan Stanley926,579$16.2M0.00%−1,000,249−51.9%Reduced
Standard Life Aberdeen plc927,171$16.2M0.03%−212,359−18.6%Reduced
TD Asset Management Inc1,205,272$21.1M0.02%+667,742+124.2%Added
Apeiron Capital Ltd1,309,241$22.9M26.48%−1,700−0.1%Reduced
Norges Bank1,373,943$24.0M0.00%+1,373,943New
Pictet Asset Management Holding SA1,383,775$24.4M0.02%−220,388−13.7%Reduced
Polymer Capital Management (HK) LTD1,421,155$24.9M3.87%+603,879+73.9%Added
Citadel Advisors LLC2,475,708$43.3M0.03%+2,272,996+1,121.3%Added
Geode Capital Management, LLC3,147,480$55.1M0.00%+14,745+0.5%Added