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Skye Bioscience, Inc.

SKYE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001516551

In the last 90 days, Skye Bioscience, Inc. insiders filed 0 open-market purchases and 3 sales; 42 institutions reported holding it in 13F filings for Q2 2026, worth $11.1M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Skye Bioscience, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
50
−8 vs. Q3 2025
Shares held
16.1M
−3.75M (−18.9%) vs. Q3 2025
Total value
$12.1M
−$66.0M (−84.5%) vs. Q3 2025
New holders
15
6 more added
Sold out
23
10 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SKYE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 50 institutions
Q1 2021: 1 institutionQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 3 institutionsQ1 2023: 1 institutionQ2 2023: 1 institutionQ3 2023: 0 institutionsQ4 2023: 1 institutionQ1 2024: 3 institutionsQ2 2024: 62 institutionsQ3 2024: 74 institutionsQ4 2024: 73 institutionsQ1 2025: 75 institutionsQ2 2025: 58 institutionsQ3 2025: 58 institutionsQ4 2025: 50 institutionsQ1 2026: 39 institutionsQ2 2026: 42 institutions
Value heldQ4 2025: $12.1M
Q1 2021: $4.00KQ2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $193Q1 2023: $207Q2 2023: $253Q3 2023: $0Q4 2023: $4.35KQ1 2024: $31.4MQ2 2024: $196.3MQ3 2024: $100.6MQ4 2024: $71.3MQ1 2025: $39.3MQ2 2025: $85.3MQ3 2025: $78.1MQ4 2025: $12.1MQ1 2026: $9.91MQ2 2026: $11.1M
Institutions holding SKYE and their total value by quarter
QuarterHoldersValue
Q2 202642$11.1M
Q1 202639$9.91M
Q4 202550$12.1M
Q3 202558$78.1M
Q2 202558$85.3M
Q1 202575$39.3M
Q4 202473$71.3M
Q3 202474$100.6M
Q2 202462$196.3M
Q1 20243$31.4M
Q4 20231$4.35K
Q3 20230$0
Q2 20231$253
Q1 20231$207
Q4 20223$193
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20211$4.00K

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Skye Bioscience, Inc.; share changes are against Q3 2025.

Institutions holding SKYE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
5AM Venture Management, LLC9,681,763$7.26M2.28%00.0%Unchanged
Versant Venture Management, LLC2,007,704$1.51M1.00%00.0%Unchanged
Baker Bros. Advisors LP1,450,638$1.09M0.01%00.0%Unchanged
Vanguard Group Inc882,785$662.1K0.00%00.0%Unchanged
Sphera Funds Management Ltd.478,928$359.1K0.08%00.0%Unchanged
Millennium Management LLC380,478$285.2K0.00%−21,897−5.4%Reduced
BlackRock, Inc.281,841$211.3K0.00%+1,980+0.7%Added
Platinum Investment Management Ltd233,095$174.8K0.04%00.0%Unchanged
Geode Capital Management, LLC210,151$157.6K0.00%+1,553+0.7%Added
Schonfeld Strategic Advisors LLC93,407$70.0K0.00%−1,093,807−92.1%Reduced
State Street Corp75,326$56.5K0.00%00.0%Unchanged
XTX Topco Ltd53,040$39.8K0.00%+53,040New
Two Sigma Investments, LP51,706$38.8K0.00%−40,612−44.0%Reduced
Two Sigma Advisers, LP40,982$30.7K0.00%+40,982New
HRT Financial LP27,348$20.0K0.00%+27,348New
Jane Street Group, LLC24,615$18.5K0.00%+11,878+93.3%Added
Engineers Gate Manager LP23,138$17.3K0.00%+23,138New
Gsa Capital Partners LLP22,877$17.0K0.00%+22,877New
Barclays PLC21,251$15.9K0.00%+21,251New
Northern Trust Corp20,142$15.1K0.00%−8,862−30.6%Reduced
Group One Trading, L.P.17,697$13.3K0.00%+15,287+634.3%Added
R Squared Ltd14,782$11.1K0.01%+14,782New
UBS Group AG13,286$9.96K0.00%−16,704−55.7%Reduced
Capital Advisors Inc10,000$7.50K0.00%00.0%Unchanged
Simplex Trading, LLC6,331$4.75K0.00%+6,331New
Morgan Stanley4,269$3.20K0.00%−683−13.8%Reduced
Federated Hermes, Inc.1,158$8680.00%+1,158New
FMR LLC748$5610.00%−11,137−93.7%Reduced
Bank of America Corp586$4380.00%+445+315.6%Added
BNP Paribas Arbitrage, SA510$3820.00%00.0%Unchanged
National Bank of Canada400$2950.00%+400New
Fortitude Family Office, LLC385$2890.00%+271+237.7%Added
JPMorgan Chase & Co66$490.00%+66New
Zurcher Kantonalbank (Zurich Cantonalbank)52$390.00%−29,213−99.8%Reduced
Federation des caisses Desjardins du Quebec51$380.00%00.0%Unchanged
Rockefeller Capital Management L.P.39$290.00%00.0%Unchanged
TD Waterhouse Canada Inc.25$180.00%00.0%Unchanged
Optiver Holding B.V.20$150.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.18$130.00%00.0%Unchanged
Dynamic Wealth Strategies, LLC8$60.00%+8New
CoreCap Advisors, LLC8$60.00%+8New
Plante Moran Financial Advisors, LLC3$20.00%00.0%Unchanged
McGuire Capital Advisors Inc2$20.00%+2New
Advisor Group Holdings, Inc.2$10.00%−16−88.9%Reduced
Wells Fargo & Company1$10.00%00.0%Unchanged
Harbour Investments, Inc.1$10.00%00.0%Unchanged
IFP Advisors, Inc1$10.00%00.0%Unchanged
PFS Partners, LLC1$10.00%00.0%Unchanged
Tucker Asset Management LLC1$10.00%+1New
Royal Bank of Canada124$00.00%−277−69.1%Reduced
Ensign Peak Advisors, Inc0$00.00%−767,287−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−620,395−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−456,163−100.0%Sold out
Mirae Asset Global ETFs Holdings Ltd.0$00.00%−269,734−100.0%Sold out
Marshall Wace, LLP0$00.00%−251,645−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−106,270−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−73,126−100.0%Sold out
Capital Advisors Wealth Management, LLC0$00.00%−44,517−100.0%Sold out
Bridgeway Capital Management, LLC0$00.00%−42,000−100.0%Sold out
Citadel Advisors LLC0$00.00%−28,852−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−28,735−100.0%Sold out
LPL Financial LLC0$00.00%−25,512−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−16,658−100.0%Sold out
Quadrature Capital Ltd0$00.00%−16,408−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−13,397−100.0%Sold out
Deutsche Bank AG0$00.00%−5,922−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−4,418−100.0%Sold out
MAI Capital Management0$00.00%−32−100.0%Sold out
Groupe la Francaise0$00.00%−14−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−9−100.0%Sold out
Citigroup Inc0$00.00%−1−100.0%Sold out
CWM, LLC0$00.00%−90−100.0%Sold out
TSFG, LLC0$00.00%−4−100.0%Sold out