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Schrodinger, Inc.

SDGR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001490978

In the last 90 days, Schrodinger, Inc. insiders filed 0 open-market purchases and 2 sales; 231 institutions reported holding it in 13F filings for Q2 2026, worth $1.05B in total; superinvestors Gates Foundation Trust and ARK Invest hold it.

13F holders, Q4 2025

Institutional positions in Schrodinger, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
223
−2 vs. Q3 2025
Shares held
69.6M
−17.1K (0.0%) vs. Q3 2025
Total value
$1.24B
−$152.0M (−10.9%) vs. Q3 2025
New holders
27
77 more added
Sold out
29
80 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SDGR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 223 institutions
Q1 2021: 219 institutionsQ2 2021: 229 institutionsQ3 2021: 223 institutionsQ4 2021: 216 institutionsQ1 2022: 201 institutionsQ2 2022: 198 institutionsQ3 2022: 196 institutionsQ4 2022: 171 institutionsQ1 2023: 184 institutionsQ2 2023: 240 institutionsQ3 2023: 236 institutionsQ4 2023: 238 institutionsQ1 2024: 223 institutionsQ2 2024: 207 institutionsQ3 2024: 208 institutionsQ4 2024: 212 institutionsQ1 2025: 218 institutionsQ2 2025: 233 institutionsQ3 2025: 225 institutionsQ4 2025: 223 institutionsQ1 2026: 229 institutionsQ2 2026: 231 institutions
Value heldQ4 2025: $1.24B
Q1 2021: $2.76BQ2 2021: $2.97BQ3 2021: $2.16BQ4 2021: $1.46BQ1 2022: $1.46BQ2 2022: $1.24BQ3 2022: $1.23BQ4 2022: $915.1MQ1 2023: $1.33BQ2 2023: $2.92BQ3 2023: $1.60BQ4 2023: $2.05BQ1 2024: $1.58BQ2 2024: $1.15BQ3 2024: $1.12BQ4 2024: $1.19BQ1 2025: $1.30BQ2 2025: $1.43BQ3 2025: $1.40BQ4 2025: $1.24BQ1 2026: $748.5MQ2 2026: $1.05B
Institutions holding SDGR and their total value by quarter
QuarterHoldersValue
Q2 2026231$1.05B
Q1 2026229$748.5M
Q4 2025223$1.24B
Q3 2025225$1.40B
Q2 2025233$1.43B
Q1 2025218$1.30B
Q4 2024212$1.19B
Q3 2024208$1.12B
Q2 2024207$1.15B
Q1 2024223$1.58B
Q4 2023238$2.05B
Q3 2023236$1.60B
Q2 2023240$2.92B
Q1 2023184$1.33B
Q4 2022171$915.1M
Q3 2022196$1.23B
Q2 2022198$1.24B
Q1 2022201$1.46B
Q4 2021216$1.46B
Q3 2021223$2.16B
Q2 2021229$2.97B
Q1 2021219$2.76B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Schrodinger, Inc.; share changes are against Q3 2025.

Institutions holding SDGR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.9,517,096$170.2M0.00%−44,043−0.5%Reduced
Gates Foundation TrustSuperinvestorGates Foundation Trust6,981,664$124.8M0.35%00.0%Unchanged
Vanguard Group Inc6,464,426$115.6M0.00%+125,349+2.0%Added
Sumitomo Mitsui Trust Holdings, Inc.4,714,767$84.3M0.05%+160,198+3.5%Added
Rubric Capital Management LP4,171,498$74.6M0.89%−1,097,319−20.8%Reduced
UBS Asset Management Americas Inc3,717,890$66.5M0.01%+414,231+12.5%Added
Nikko Asset Management Americas, Inc.2,819,670$50.4M0.58%+180,735+6.8%Added
Massachusetts Financial Services Co2,291,349$41.0M0.01%+218,916+10.6%Added
Stephens Investment Management Group LLC2,250,098$40.2M0.52%+57,064+2.6%Added
Lazard Asset Management LLC2,134,968$38.2M0.06%−211,473−9.0%Reduced
State Street Corp2,131,906$38.1M0.00%−73,128−3.3%Reduced
ARK Investment Management LLCSuperinvestorARK Invest2,111,829$37.8M0.25%+239,152+12.8%Added
UBS Group AG1,442,799$25.8M0.01%+489,059+51.3%Added
Geode Capital Management, LLC1,384,788$24.8M0.00%+108,005+8.5%Added
Morgan Stanley1,186,698$21.2M0.00%−550,732−31.7%Reduced
American Century Companies Inc1,107,677$19.8M0.01%+22,249+2.0%Added
Dimensional Fund Advisors LP1,012,631$18.1M0.00%+161,242+18.9%Added
Millennium Management LLC978,172$17.5M0.01%−573,549−37.0%Reduced
Baillie Gifford & Co835,488$14.9M0.01%−139,307−14.3%Reduced
Goldman Sachs Group Inc669,468$12.0M0.00%+107,346+19.1%Added
Northern Trust Corp555,374$9.93M0.00%−30,606−5.2%Reduced
Charles Schwab Investment Management Inc515,903$9.22M0.00%+30,447+6.3%Added
Two Sigma Advisers, LP506,600$9.06M0.02%−234,500−31.6%Reduced
Man Group plc441,363$7.89M0.02%+278,189+170.5%Added
Tudor Investment Corp Et Al438,925$7.85M0.04%+102,546+30.5%Added
Two Sigma Investments, LP436,792$7.81M0.01%−354,272−44.8%Reduced
Bank of New York Mellon Corp310,590$5.55M0.00%−28,707−8.5%Reduced
Parkman Healthcare Partners LLC298,939$5.35M0.51%−41,248−12.1%Reduced
Connor, Clark & Lunn Investment Management Ltd.273,254$4.89M0.01%+185,632+211.9%Added
Fred Alger Management, LLC269,825$4.82M0.02%+166,706+161.7%Added
Principal Financial Group Inc268,360$4.80M0.00%−2,775−1.0%Reduced
Allianz Asset Management GmbH248,053$4.44M0.01%+248,053New
Jupiter Asset Management Ltd223,892$4.00M0.03%−10,733−4.6%Reduced
Algert Global LLC211,427$3.78M0.06%+177,537+523.9%Added
Perceptive Advisors LLC202,400$3.62M0.07%+202,400New
Public Sector Pension Investment Board194,267$3.47M0.01%−24,374−11.1%Reduced
Invesco Ltd.190,763$3.41M0.00%+10,307+5.7%Added
Citadel Advisors LLC187,915$3.36M0.00%−98,436−34.4%Reduced
Allspring Global Investments Holdings, LLC185,007$3.31M0.01%−14,363−7.2%Reduced
HRT Financial LP164,576$2.94M0.01%+118,157+254.5%Added
AQR Capital Management LLC161,721$2.89M0.00%+126,303+356.6%Added
Susquehanna Portfolio Strategies, LLC158,162$2.83M0.04%+129,877+459.2%Added
Tocqueville Asset Management L.P.157,000$2.81M0.04%−15,250−8.9%Reduced
Rhumbline Advisers154,450$2.76M0.00%−11,479−6.9%Reduced
FMR LLC151,323$2.71M0.00%−46,445−23.5%Reduced
Legal & General Group Plc147,735$2.64M0.00%−8,980−5.7%Reduced
First Trust Advisors LP136,918$2.45M0.00%−26,501−16.2%Reduced
Trexquant Investment LP135,024$2.41M0.02%+135,024New
Slow Capital, Inc.131,263$2.35M0.28%+37,374+39.8%Added
Bank of America Corp130,932$2.34M0.00%−67,753−34.1%Reduced
Swiss National Bank127,200$2.27M0.00%+2,800+2.3%Added
Nuveen, LLC125,040$2.24M0.00%−58,440−31.9%Reduced
Tejara Capital Ltd121,697$2.18M0.90%−8,000−6.2%Reduced
BNP Paribas Arbitrage, SA118,692$2.12M0.00%+68,364+135.8%Added
Wells Fargo & Company112,525$2.01M0.00%+15,317+15.8%Added
Barclays PLC111,371$1.99M0.00%+12,364+12.5%Added
Citigroup Inc109,428$1.96M0.00%−45,781−29.5%Reduced
Ameriprise Financial Inc102,719$1.84M0.00%−7,781−7.0%Reduced
Jane Street Group, LLC90,716$1.62M0.00%−154,088−62.9%Reduced
Marshall Wace, LLP80,774$1.44M0.00%+42,288+109.9%Added
JPMorgan Chase & Co79,677$1.42M0.00%−1,606−2.0%Reduced
Capital Fund Management S.A.72,968$1.30M0.01%+40,785+126.7%Added
Farallon Capital Management, L.L.C.71,000$1.27M0.01%−213,000−75.0%Reduced
Davy Global Fund Management Ltd68,759$1.23M0.08%+27,385+66.2%Added
Alliancebernstein L.P.68,694$1.23M0.00%−3,290−4.6%Reduced
Verity Asset Management, Inc.65,722$1.18M0.50%+798+1.2%Added
Schonfeld Strategic Advisors LLC65,640$1.17M0.01%+39,232+148.6%Added
Engineers Gate Manager LP65,399$1.17M0.01%+52,035+389.4%Added
SG Americas Securities, LLC65,151$1.17M0.00%+27,023+70.9%Added
ExodusPoint Capital Management, LP62,483$1.12M0.01%+62,483New
California State Teachers Retirement System61,601$1.10M0.00%+3,215+5.5%Added
Price T Rowe Associates Inc60,897$1.09M0.00%+7,919+14.9%Added
Mirae Asset Global ETFs Holdings Ltd.54,726$978.5K0.00%−3,388−5.8%Reduced
Susquehanna International Group, LLP52,870$945.3K0.00%+42,171+394.2%Added
Great West Life Assurance Co52,861$944.0K0.00%−13,659−20.5%Reduced
Prudential Financial Inc52,510$938.9K0.00%−3,780−6.7%Reduced
Qube Research & Technologies Ltd52,091$931.4K0.00%−12,234−19.0%Reduced
Royal Bank of Canada51,571$922.0K0.00%−377,259−88.0%Reduced
Pier 88 Investment Partners LLC50,870$909.6K0.20%−3,320−6.1%Reduced
LPL Financial LLC50,709$906.7K0.00%−199−0.4%Reduced
Kestra Advisory Services, LLC50,427$901.6K0.00%+8,966+21.6%Added
Nano Cap New Millennium Growth Fund L P50,000$894.0K0.76%+50,000New
Fox Run Management, L.L.C.47,831$855.2K0.13%+30,042+168.9%Added
Wesbanco Bank Inc46,900$838.6K0.02%+46,900New
Deutsche Bank AG46,332$828.4K0.00%+4,271+10.2%Added
New York State Teachers Retirement System45,900$821.0K0.00%00.0%Unchanged
Brevan Howard Capital Management LP44,592$797.3K0.02%+15,182+51.6%Added
EntryPoint Capital, LLC44,319$792.4K0.31%+28,924+187.9%Added
Stifel Financial Corp40,411$722.5K0.00%−4,880−10.8%Reduced
SEI Investments Co39,139$699.8K0.00%+8,240+26.7%Added
Thrivent Financial for Lutherans38,559$689.0K0.00%−1,888−4.7%Reduced
Aquatic Capital Management LLC38,058$680.5K0.02%+38,058New
State of Wisconsin Investment Board37,865$677.0K0.00%−3,227−7.9%Reduced
Point72 Asset Management, L.P.37,382$668.4K0.00%+37,382New
Deerfield Management Company, L.P. (Series C)33,987$607.7K0.01%+33,987New
Quest Partners LLC32,980$589.7K0.03%−90−0.3%Reduced
MetLife Investment Management32,932$588.8K0.00%00.0%Unchanged
IMC-Chicago, LLC32,708$584.8K0.01%+1,661+5.3%Added
Graham Capital Management, L.P.31,294$559.5K0.02%+31,294New
Intech Investment Management LLC31,286$559.4K0.00%−2,660−7.8%Reduced