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Revolution Medicines, Inc.

RVMD
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001628171

In the last 90 days, Revolution Medicines, Inc. insiders filed 0 open-market purchases and 17 sales; 693 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; Duquesne Family Office is the only superinvestor holding it.

Other share classesRVMDW

13F holders, Q4 2025

Institutional positions in Revolution Medicines, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+69 vs. Q3 2025
Shares held
199.3M
+7.61M (+4.0%) vs. Q3 2025
Total value
$15.9B
+$6.92B (+77.3%) vs. Q3 2025
New holders
107
136 more added
Sold out
38
101 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RVMD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 128 institutionsQ2 2021: 130 institutionsQ3 2021: 114 institutionsQ4 2021: 117 institutionsQ1 2022: 126 institutionsQ2 2022: 135 institutionsQ3 2022: 142 institutionsQ4 2022: 135 institutionsQ1 2023: 152 institutionsQ2 2023: 139 institutionsQ3 2023: 168 institutionsQ4 2023: 184 institutionsQ1 2024: 210 institutionsQ2 2024: 223 institutionsQ3 2024: 255 institutionsQ4 2024: 281 institutionsQ1 2025: 284 institutionsQ2 2025: 308 institutionsQ3 2025: 323 institutionsQ4 2025: 387 institutionsQ1 2026: 514 institutionsQ2 2026: 693 institutions
Value heldQ4 2025: $15.9B
Q1 2021: $3.05BQ2 2021: $2.23BQ3 2021: $1.99BQ4 2021: $1.85BQ1 2022: $1.89BQ2 2022: $1.49BQ3 2022: $1.74BQ4 2022: $2.10BQ1 2023: $2.34BQ2 2023: $2.99BQ3 2023: $3.11BQ4 2023: $4.59BQ1 2024: $5.18BQ2 2024: $6.54BQ3 2024: $7.74BQ4 2024: $8.45BQ1 2025: $6.83BQ2 2025: $7.02BQ3 2025: $8.96BQ4 2025: $15.9BQ1 2026: $19.1BQ2 2026: $40.1B
Institutions holding RVMD and their total value by quarter
QuarterHoldersValue
Q2 2026693$40.1B
Q1 2026514$19.1B
Q4 2025387$15.9B
Q3 2025323$8.96B
Q2 2025308$7.02B
Q1 2025284$6.83B
Q4 2024281$8.45B
Q3 2024255$7.74B
Q2 2024223$6.54B
Q1 2024210$5.18B
Q4 2023184$4.59B
Q3 2023168$3.11B
Q2 2023139$2.99B
Q1 2023152$2.34B
Q4 2022135$2.10B
Q3 2022142$1.74B
Q2 2022135$1.49B
Q1 2022126$1.89B
Q4 2021117$1.85B
Q3 2021114$1.99B
Q2 2021130$2.23B
Q1 2021128$3.05B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Revolution Medicines, Inc.; share changes are against Q3 2025.

Institutions holding RVMD in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Danske Bank A/S3,100$246.9K0.00%+1,000+47.6%Added
Temasek Holdings (Private) Ltd3,148$250.7K0.00%+3,148New
Arrowpoint Investment Partners (Singapore) Pte. Ltd.3,200$254.9K0.04%−1,189−27.1%Reduced
Virtus Investment Advisers, Inc.3,371$268.5K0.07%+603+21.8%Added
MetLife Investment Management3,538$281.8K0.00%+648+22.4%Added
MAI Capital Management3,626$288.8K0.00%−2,000−35.5%Reduced
GF Fund Management Co. Ltd.3,798$302.5K0.01%−224−5.6%Reduced
US Bancorp3,861$307.5K0.00%+693+21.9%Added
SCS Capital Management LLC3,867$308.0K0.00%+3,867New
Virginia Retirement Systems Et Al3,900$310.6K0.00%+3,900New
Baader Bank INC4,000$318.6K0.03%+4,000New
Meeder Advisory Services, Inc.4,006$319.1K0.01%+4,006New
Envestnet Asset Management Inc4,076$324.7K0.00%−1,924−32.1%Reduced
STRS Ohio4,151$330.6K0.00%+7+0.2%Added
Centric Wealth Management3,416$331.9K0.07%+3,416New
KBC Group NV4,199$334.0K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.4,376$348.6K0.00%−4,820−52.4%Reduced
Pathstone Holdings, LLC4,529$360.7K0.00%+205+4.7%Added
Everence Capital Management Inc4,630$369.0K0.02%00.0%Unchanged
Laird Norton Trust Company, LLC4,729$376.7K0.01%+4,729New
Principal Financial Group Inc4,739$377.5K0.00%−1,656−25.9%Reduced
National Asset Management, Inc.4,754$378.7K0.02%+4,754New
Oxford Asset Management LLP4,888$389.3K0.14%+4,888New
Forum Financial Management, LP4,982$396.8K0.01%+23+0.5%Added
Fishman Jay A Ltd5,000$398.3K0.03%00.0%Unchanged
Sandia Investment Management LP5,000$398.3K0.99%00.0%Unchanged
Park Avenue Institutional Advisers LLC5,115$407.4K40.50%+5,115New
Skopos Labs, Inc.5,164$415.8K0.02%+5,164New
Sumitomo Mitsui Trust Holdings, Inc.5,498$437.9K0.00%+5,498New
Abel Hall, LLC5,508$438.7K0.10%+5,508New
Summit Trail Advisors, LLC5,861$466.8K0.01%+1,357+30.1%Added
StepStone Group LP5,971$475.6K0.25%+5,971New
Smith, Moore & Co.6,000$477.9K0.04%00.0%Unchanged
CIBC Asset Management Inc6,038$480.9K0.00%+917+17.9%Added
North Dakota State Investment Board6,092$485.2K0.02%+6,092New
Fox Run Management, L.L.C.6,391$509.0K0.08%+6,391New
O'Shaughnessy Asset Management, LLC6,532$520.3K0.00%+6,532New
VARCOV Co.6,532$520.3K0.21%+6,532New
Swiss Life Asset Management Ltd6,723$535.5K0.00%+443+7.1%Added
Daiwa Securities Group Inc.6,835$545.0K0.00%−20.0%Reduced
PSP Research LLC6,872$547.4K0.48%+6,872New
XTX Topco Ltd6,939$552.7K0.01%+6,939New
Nelson, Van Denburg & Campbell Wealth Management Group, LLC7,325$583.4K0.02%−1,173−13.8%Reduced
West Michigan Advisors, LLC7,604$605.7K0.14%+7,604New
J. Safra Sarasin Holding AG7,766$618.6K0.01%+7,766New
Silvercrest Asset Management Group LLC7,905$629.6K0.00%+7,905New
Flax Pond Capital, LLC7,933$631.9K0.47%+7,933New
M&T Bank Corp8,060$642.4K0.00%+8,060New
Aigen Investment Management, LP8,129$647.5K0.15%−11,117−57.8%Reduced
Prudential Financial Inc8,257$657.7K0.00%−4,882−37.2%Reduced
Acuta Capital Partners, LLC8,411$669.9K0.45%00.0%Unchanged
Maryland State Retirement & Pension System8,423$670.9K0.01%00.0%Unchanged
Amalgamated Bank8,439$672.0K0.00%−251−2.9%Reduced
ProShare Advisors LLC8,539$680.1K0.00%+1,878+28.2%Added
Xponance, Inc.8,826$703.0K0.01%+307+3.6%Added
Utah Retirement Systems9,161$729.7K0.01%00.0%Unchanged
Simplex Trading, LLC9,644$768.1K0.02%+9,644New
SBI Okasan Asset Management Co.Ltd.9,900$797.1K0.04%+9,900New
The PNC Financial Services Group, Inc.10,066$801.8K0.00%+125+1.3%Added
J. Goldman & Co LP10,179$810.8K0.03%−4,187−29.1%Reduced
Aristotle Atlantic Partners, LLC10,410$829.2K0.04%+10,410New
Captrust Financial Advisors10,469$833.9K0.00%−621−5.6%Reduced
Beaumont Financial Advisors, LLC10,520$837.9K0.06%00.0%Unchanged
HRT Financial LP11,192$891.0K0.00%−67,929−85.9%Reduced
Teachers Retirement System of the State of Kentucky12,096$963.0K0.01%00.0%Unchanged
Knights of Columbus Asset Advisors LLC12,114$964.9K0.05%−459−3.7%Reduced
Natixis12,459$992.4K0.00%+12,459New
Calamos Advisors LLC12,460$992.4K0.00%+12,460New
Himension Fund12,624$1.01M0.06%−8,797−41.1%Reduced
Winton Group Ltd12,783$1.02M0.04%+12,783New
Wells Fargo & Company13,120$1.04M0.00%+4,200+47.1%Added
JustInvest LLC13,369$1.06M0.01%+1,061+8.6%Added
Public Employees Retirement Association of Colorado13,423$1.07M0.00%00.0%Unchanged
Private Advisor Group, LLC13,429$1.07M0.01%+2,186+19.4%Added
Engineers Gate Manager LP13,456$1.07M0.01%−16,936−55.7%Reduced
Neo Ivy Capital Management13,498$1.08M0.17%−13,764−50.5%Reduced
Cerity Partners LLC13,988$1.11M0.00%−715−4.9%Reduced
Federation des caisses Desjardins du Quebec14,018$1.12M0.00%+2,171+18.3%Added
Jasper Ridge Partners, L.P.14,368$1.14M0.03%+14,368New
Bridgefront Capital, LLC15,556$1.24M0.31%+15,556New
Tang Capital Management LLC15,640$1.25M0.06%−84,360−84.4%Reduced
New York Life Investment Management LLC15,700$1.25M0.01%−2,209−12.3%Reduced
LPL Financial LLC15,787$1.26M0.00%+9,928+169.4%Added
Fred Alger Management, LLC16,250$1.29M0.01%−100,530−86.1%Reduced
Great West Life Assurance Co16,549$1.32M0.00%−18,334−52.6%Reduced
SG Americas Securities, LLC16,723$1.33M0.00%+6,009+56.1%Added
FORA Capital, LLC17,357$1.37M0.17%+10,988+172.5%Added
B. Metzler seel. Sohn & Co. AG17,440$1.39M0.01%−8,381−32.5%Reduced
Persistent Asset Partners Ltd17,537$1.40M0.67%+3,910+28.7%Added
Neuberger Berman Group LLC18,358$1.46M0.00%+1,063+6.1%Added
BIT Capital GmbH18,400$1.47M0.06%+16,878+1,108.9%Added
Platinum Investment Management Ltd18,652$1.49M0.34%−1,924−9.4%Reduced
Landscape Capital Management, L.L.C.18,845$1.50M0.10%+18,845New
Nan Fung Group Holdings Ltd19,253$1.53M1.37%00.0%Unchanged
Amundi20,067$1.60M0.00%+20,067New
Advisor Group Holdings, Inc.20,430$1.63M0.00%−1,705−7.7%Reduced
Quest Partners LLC20,664$1.65M0.09%+8,751+73.5%Added
Teacher Retirement System of Texas20,820$1.66M0.01%−13,504−39.3%Reduced
Harbor Capital Advisors, Inc.21,076$1.68M0.13%−514−2.4%Reduced
Sterling Capital Management LLC21,269$1.69M0.03%+10,553+98.5%Added