Revolution Medicines, Inc.
RVMD- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001628171
In the last 90 days, Revolution Medicines, Inc. insiders filed 0 open-market purchases and 16 sales; 693 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; Duquesne Family Office is the only superinvestor holding it.
Other share classesRVMDW
13F holders, Q4 2025
Institutional positions in Revolution Medicines, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 387
- +69 vs. Q3 2025
- Shares held
- 199.3M
- +7.61M (+4.0%) vs. Q3 2025
- Total value
- $15.9B
- +$6.92B (+77.3%) vs. Q3 2025
- New holders
- 107
- 136 more added
- Sold out
- 38
- 101 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RVMD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 693 | $40.1B |
| Q1 2026 | 514 | $19.1B |
| Q4 2025 | 387 | $15.9B |
| Q3 2025 | 323 | $8.96B |
| Q2 2025 | 308 | $7.02B |
| Q1 2025 | 284 | $6.83B |
| Q4 2024 | 281 | $8.45B |
| Q3 2024 | 255 | $7.74B |
| Q2 2024 | 223 | $6.54B |
| Q1 2024 | 210 | $5.18B |
| Q4 2023 | 184 | $4.59B |
| Q3 2023 | 168 | $3.11B |
| Q2 2023 | 139 | $2.99B |
| Q1 2023 | 152 | $2.34B |
| Q4 2022 | 135 | $2.10B |
| Q3 2022 | 142 | $1.74B |
| Q2 2022 | 135 | $1.49B |
| Q1 2022 | 126 | $1.89B |
| Q4 2021 | 117 | $1.85B |
| Q3 2021 | 114 | $1.99B |
| Q2 2021 | 130 | $2.23B |
| Q1 2021 | 128 | $3.05B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Revolution Medicines, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 16,719,886 | $1.33B | 0.02% | +1,056,792+6.7% | Added |
| Farallon Capital Management, L.L.C. | 14,582,796 | $1.16B | 6.04% | −42,896−0.3% | Reduced |
| Janus Henderson Group PLC | 12,303,502 | $980.0M | 0.44% | +947,448+8.3% | Added |
| Baker Bros. Advisors LP | 9,455,357 | $753.1M | 4.41% | 00.0% | Unchanged |
| BlackRock, Inc. | 8,926,656 | $711.0M | 0.01% | +598,898+7.2% | Added |
| FMR LLC | 8,587,981 | $684.0M | 0.03% | −813,706−8.7% | Reduced |
| Nextech Invest, Ltd. | 7,601,087 | $605.4M | 58.53% | 00.0% | Unchanged |
| Wellington Management Group LLP | 6,987,639 | $556.6M | 0.10% | −2,825,797−28.8% | Reduced |
| Paradigm Biocapital Advisors LP | 6,644,403 | $529.2M | 14.17% | +421,112+6.8% | Added |
| Bellevue Group AG | 5,005,719 | $398.7M | 7.56% | −568,119−10.2% | Reduced |
| State Street Corp | 4,109,290 | $327.3M | 0.01% | −1,145,349−21.8% | Reduced |
| Price T Rowe Associates Inc | 3,404,717 | $271.2M | 0.03% | −468,989−12.1% | Reduced |
| BVF Inc | 3,356,782 | $267.4M | 9.00% | −618,131−15.6% | Reduced |
| Alphabet Inc. | 3,345,102 | $266.4M | 10.33% | −788,175−19.1% | Reduced |
| Geode Capital Management, LLC | 3,161,963 | $251.9M | 0.02% | +16,323+0.5% | Added |
| UBS Group AG | 3,087,937 | $246.0M | 0.05% | +1,998,972+183.6% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,894,613 | $230.6M | 2.96% | −755,729−20.7% | Reduced |
| Westfield Capital Management Co LP | 2,845,013 | $226.6M | 0.94% | +331,046+13.2% | Added |
| General Atlantic LLC | 2,812,928 | $224.0M | 7.80% | +338,500+13.7% | Added |
| Casdin Capital, LLC | 2,577,333 | $205.3M | 12.75% | −70,000−2.6% | Reduced |
| Woodline Partners LP | 2,500,895 | $199.2M | 0.77% | −414,988−14.2% | Reduced |
| Goldman Sachs Group Inc | 2,491,583 | $198.5M | 0.03% | +1,753,557+237.6% | Added |
| Norges Bank | 2,455,347 | $195.6M | 0.02% | +2,455,347 | New |
| Adage Capital Partners GP, L.L.C. | 2,205,555 | $175.7M | 0.27% | +1,463,155+197.1% | Added |
| T. Rowe Price Investment Management, Inc. | 2,200,376 | $175.3M | 0.11% | −2,581,942−54.0% | Reduced |
| Lunate Capital Ltd | 2,196,200 | $174.9M | 66.20% | 00.0% | Unchanged |
| Avoro Capital Advisors LLC | 2,170,000 | $172.8M | 1.70% | +2,170,000 | New |
| Ameriprise Financial Inc | 2,056,857 | $163.8M | 0.04% | +832,098+67.9% | Added |
| Polar Capital Holdings Plc | 2,013,791 | $160.4M | 0.73% | +1,535,686+321.2% | Added |
| Logos Global Management LP | 2,000,000 | $159.3M | 10.62% | +250,000+14.3% | Added |
| Holocene Advisors, LP | 1,907,948 | $152.0M | 0.32% | −1,529,335−44.5% | Reduced |
| Charles Schwab Investment Management Inc | 1,683,729 | $134.1M | 0.02% | +48,334+3.0% | Added |
| D. E. Shaw & Co., Inc. | 1,613,730 | $128.5M | 0.10% | +801,451+98.7% | Added |
| Rock Springs Capital Management LP | 1,335,270 | $106.4M | 5.46% | 00.0% | Unchanged |
| Siren, L.L.C. | 1,335,075 | $106.3M | 3.17% | +291,355+27.9% | Added |
| Citadel Advisors LLC | 1,302,361 | $103.7M | 0.07% | +122,276+10.4% | Added |
| Caligan Partners LP | 1,283,900 | $102.3M | 9.36% | +219,651+20.6% | Added |
| Integral Health Asset Management, LLC | 1,200,000 | $95.6M | 4.84% | +800,000+200.0% | Added |
| Dimensional Fund Advisors LP | 1,161,646 | $92.5M | 0.02% | −279,172−19.4% | Reduced |
| Jefferies Financial Group Inc. | 1,141,195 | $90.9M | 0.74% | +1,128,195+8,678.4% | Added |
| Pictet Asset Management Holding SA | 1,137,121 | $90.7M | 0.09% | −174,620−13.3% | Reduced |
| Jane Street Group, LLC | 1,090,416 | $86.9M | 0.10% | +492,961+82.5% | Added |
| Franklin Resources Inc | 1,060,171 | $84.4M | 0.02% | +108,681+11.4% | Added |
| Candriam Luxembourg S.C.A. | 1,030,992 | $82.1M | 0.41% | +162,268+18.7% | Added |
| Hood River Capital Management LLC | 945,585 | $75.3M | 0.83% | +17,462+1.9% | Added |
| AH Capital Management, L.L.C. | 921,099 | $73.4M | 4.64% | −1,827,424−66.5% | Reduced |
| AIHC Capital Management Ltd | 900,392 | $71.7M | 67.21% | +900,392 | New |
| Bank of America Corp | 879,845 | $70.1M | 0.01% | +125,978+16.7% | Added |
| Northern Trust Corp | 850,323 | $67.7M | 0.01% | −9,225−1.1% | Reduced |
| Millennium Management LLC | 800,118 | $63.7M | 0.05% | +371,809+86.8% | Added |
| Frazier Life Sciences Management, L.P. | 797,455 | $63.5M | 1.71% | −200,000−20.1% | Reduced |
| Morgan Stanley | 651,732 | $51.9M | 0.00% | −782,910−54.6% | Reduced |
| First Turn Management, LLC | 638,385 | $50.8M | 5.81% | −4,665−0.7% | Reduced |
| BNP Paribas Arbitrage, SA | 619,387 | $49.3M | 0.03% | +194,706+45.8% | Added |
| DAFNA Capital Management LLC | 604,514 | $48.1M | 11.18% | −52,662−8.0% | Reduced |
| Bank of New York Mellon Corp | 542,069 | $43.2M | 0.01% | +12,799+2.4% | Added |
| MIC Capital Management UK LLP | 508,569 | $40.5M | 9.18% | 00.0% | Unchanged |
| MPM Oncology Impact Management LP | 505,672 | $40.3M | 4.61% | +189,950+60.2% | Added |
| Royal Bank of Canada | 503,721 | $40.1M | 0.01% | +311,392+161.9% | Added |
| American Century Companies Inc | 467,360 | $37.2M | 0.02% | +16,346+3.6% | Added |
| Point72 Asset Management, L.P. | 446,616 | $35.6M | 0.06% | +446,616 | New |
| TCG Crossover Management, LLC | 436,473 | $34.8M | 1.15% | 00.0% | Unchanged |
| Frontier Capital Management Co LLC | 430,768 | $34.3M | 0.36% | +307,988+250.8% | Added |
| Two Sigma Investments, LP | 421,735 | $33.6M | 0.05% | +412,628+4,530.9% | Added |
| JPMorgan Chase & Co | 421,627 | $33.6M | 0.00% | −2,076,700−83.1% | Reduced |
| Balyasny Asset Management LLC | 415,207 | $33.1M | 0.06% | +319,611+334.3% | Added |
| Nuveen, LLC | 406,241 | $32.4M | 0.01% | +68,767+20.4% | Added |
| Boxer Capital Management, LLC | 400,000 | $31.9M | 6.97% | 00.0% | Unchanged |
| Lord, Abbett & Co. LLC | 399,484 | $31.8M | 0.10% | +399,484 | New |
| Marshall Wace, LLP | 386,191 | $30.8M | 0.03% | +225,095+139.7% | Added |
| Eventide Asset Management, LLC | 378,261 | $30.1M | 0.47% | −216,777−36.4% | Reduced |
| TD Asset Management Inc | 370,520 | $29.5M | 0.02% | −165,084−30.8% | Reduced |
| Checkpoint Capital L.P. | 370,000 | $29.5M | 9.34% | −122,300−24.8% | Reduced |
| Invesco Ltd. | 367,851 | $29.3M | 0.00% | +166,909+83.1% | Added |
| Defilade Capital Management, L.P. | 363,454 | $28.9M | 3.92% | +363,454 | New |
| UBS Asset Management Americas Inc | 349,412 | $27.8M | 0.01% | +8,045+2.4% | Added |
| Mass General Brigham, Inc | 344,091 | $27.4M | 3.38% | +344,091 | New |
| Boothbay Fund Management, LLC | 327,152 | $26.1M | 0.68% | +62,144+23.4% | Added |
| Voloridge Investment Management, LLC | 322,289 | $25.7M | 0.09% | +173,144+116.1% | Added |
| Nicholas Investment Partners, LP | 317,711 | $25.3M | 1.84% | +49,800+18.6% | Added |
| Jennison Associates LLC | 305,260 | $24.3M | 0.01% | +305,260 | New |
| Vestal Point Capital, LP | 295,000 | $23.5M | 0.86% | −335,000−53.2% | Reduced |
| California Public Employees Retirement System | 291,006 | $23.2M | 0.01% | +60,032+26.0% | Added |
| Two Sigma Advisers, LP | 287,646 | $22.9M | 0.04% | +248,655+637.7% | Added |
| Swiss National Bank | 276,331 | $22.0M | 0.01% | +5,500+2.0% | Added |
| Raymond James Financial Inc | 244,174 | $19.4M | 0.01% | −33,986−12.2% | Reduced |
| Fisher Asset Management, LLC | 241,057 | $19.2M | 0.01% | +233,752+3,199.9% | Added |
| Alyeska Investment Group, L.P. | 239,097 | $19.0M | 0.05% | +239,097 | New |
| Ensign Peak Advisors, Inc | 235,808 | $18.8M | 0.03% | −12,670−5.1% | Reduced |
| Catalyst Funds Management Pty Ltd | 223,569 | $17.8M | 4.13% | +13,400+6.4% | Added |
| Marsico Capital Management LLC | 219,460 | $17.5M | 0.49% | +219,460 | New |
| Decheng Capital LLC | 200,000 | $15.9M | 2.14% | −10,000−4.8% | Reduced |
| Baillie Gifford & Co | 194,959 | $15.5M | 0.01% | +194,959 | New |
| Verition Fund Management LLC | 189,333 | $15.1M | 0.08% | +53,884+39.8% | Added |
| Susquehanna International Group, LLP | 183,221 | $14.6M | 0.02% | +65,013+55.0% | Added |
| a16z Perennial Management, L.P. | 182,918 | $14.6M | 1.16% | +182,918 | New |
| Manufacturers Life Insurance Company, The | 171,543 | $13.7M | 0.01% | +2,133+1.3% | Added |
| Rhumbline Advisers | 160,448 | $12.8M | 0.01% | +6,634+4.3% | Added |
| Legal & General Group Plc | 153,380 | $12.2M | 0.00% | −2,009−1.3% | Reduced |
| PFM Health Sciences, LP | 151,453 | $12.1M | 1.22% | −179,616−54.3% | Reduced |