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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Relay Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
259
+20 vs. Q1 2026
Shares held
246.8M
+62.8M (+34.1%) vs. Q1 2026
Total value
$4.58B
+$2.75B (+150.4%) vs. Q1 2026
New holders
51
115 more added
Sold out
31
64 more reduced

5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 259 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ2 2026: $4.58B
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding RLAY in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
HighVista Strategies LLC506,235$9.47M2.16%+84,354+20.0%Added
ArrowMark Colorado Holdings LLC541,124$10.1M0.42%00.0%Unchanged
Rhenman & Partners Asset Management AB566,000$10.6M1.00%+206,000+57.2%Added
Polygon Management Ltd.570,311$10.7M1.74%+388,768+214.1%Added
Millennium Management LLC591,675$11.1M0.01%+243,942+70.2%Added
Congress Asset Management Co626,141$11.7M0.07%+7,203+1.2%Added
Invesco Ltd.692,584$13.0M0.00%+22,710+3.4%Added
EcoR1 Capital, LLC697,948$13.1M0.65%−1,206,814−63.4%Reduced
Two Sigma Investments, LP700,921$13.1M0.01%−668,228−48.8%Reduced
Jupiter Asset Management Ltd719,576$13.5M0.07%+719,576New
Raymond James Financial Inc783,065$14.7M0.00%+436,748+126.1%Added
Timothy G. Youngquist 2020 Irrevocable Trust801,464$15.0M3.01%+302,406+60.6%Added
JPMorgan Chase & Co801,657$16.0M0.00%+154,139+23.8%Added
Woodline Partners LP929,692$17.4M0.05%+250,350+36.9%Added
Connor, Clark & Lunn Investment Management Ltd.961,702$18.0M0.03%+124,664+14.9%Added
Squadron Capital Management LLC970,000$18.1M6.21%+297,500+44.2%Added
Frazier Life Sciences Management, L.P.1,015,693$19.0M0.41%+1,015,693New
Affinity Asset Advisors, LLC1,050,000$19.6M0.96%+650,000+162.5%Added
First Trust Advisors LP1,075,126$20.1M0.01%+1,075,126New
UBS Group AG1,094,980$20.5M0.00%+567,369+107.5%Added
Vanguard Fiduciary Trust Co1,224,006$22.9M0.01%+323,460+35.9%Added
Foresite Capital Management IV, LLC1,250,000$23.4M8.06%+250,000+25.0%Added
AQR Capital Management LLC1,279,473$23.9M0.01%−10,559−0.8%Reduced
Panagora Asset Management Inc1,291,182$24.2M0.07%+473,141+57.8%Added
Alphabet Inc.1,410,029$26.4M0.03%−154,144−9.9%Reduced
Elmind Capital, LP1,465,279$27.4M6.89%+928,333+172.9%Added
Charles Schwab Investment Management Inc1,500,817$28.1M0.00%+388,926+35.0%Added
Adage Capital Partners GP, L.L.C.1,740,000$32.6M0.05%−850,000−32.8%Reduced
Polar Capital Holdings Plc1,789,056$33.5M0.09%+1,789,056New
Franklin Resources Inc1,856,913$34.7M0.01%+1,807,998+3,696.2%Added
T. Rowe Price Investment Management, Inc.1,915,459$35.8M0.02%+1,915,459New
Northern Trust Corp1,953,456$36.5M0.00%+278,069+16.6%Added
Pictet Asset Management Holding SA2,077,297$39.2M0.04%+2,057,705+10,502.8%Added
Alliancebernstein L.P.4,095,600$40.8M0.01%+3,950,349+2,719.7%Added
Arrowstreet Capital, Limited Partnership2,238,929$41.9M0.02%+1,570,640+235.0%Added
MPM Oncology Impact Management LP2,415,672$45.2M2.76%+56,086+2.4%Added
Bank of America Corp2,695,108$50.4M0.00%+757,413+39.1%Added
Baker Bros. Advisors LP2,826,783$52.9M0.27%+1,666,666+143.7%Added
Vanguard Portfolio Management LLC2,892,785$54.1M0.00%+1,029,220+55.2%Added
Spruce Street Capital LP2,984,125$55.8M10.95%00.0%Unchanged
Dimensional Fund Advisors LP3,127,564$58.5M0.01%+187,028+6.4%Added
Kynam Capital Management, LP3,300,000$61.7M3.41%+1,875,741+131.7%Added
Westfield Capital Management Co LP3,343,496$62.6M0.20%+3,343,496New
Goldman Sachs Group Inc3,408,701$63.8M0.01%+866,840+34.1%Added
Siren, L.L.C.3,650,000$68.3M1.39%+3,650,000New
Morgan Stanley3,851,071$72.1M0.00%+2,419,068+168.9%Added
TCG Crossover Management, LLC4,273,356$80.0M1.92%00.0%Unchanged
Geode Capital Management, LLC4,726,576$88.4M0.00%+1,215,940+34.6%Added
Bellevue Group AG6,185,970$115.7M2.44%−1,609,272−20.6%Reduced
Nextech Invest, Ltd.6,776,506$126.8M6.02%+1,250,000+22.6%Added
Price T Rowe Associates Inc7,708,507$144.2M0.01%+5,783,569+300.5%Added
Vanguard Capital Management LLC8,964,423$167.7M0.00%+1,576,958+21.3%Added
State Street Corp10,125,381$189.5M0.01%+3,891,836+62.4%Added
Commodore Capital LP12,000,000$224.5M13.37%−5,000,000−29.4%Reduced
Perceptive Advisors LLC14,106,187$263.9M4.10%+4,355,046+44.7%Added
BlackRock, Inc.15,288,202$286.0M0.00%+2,312,903+17.8%Added
Casdin Capital, LLC16,035,240$300.0M15.02%+1,616,666+11.2%Added
FMR LLC20,110,113$376.3M0.02%+16,414,682+444.2%Added
SB Investment Advisers (UK) Ltd27,904,963$522.1M6.81%00.0%Unchanged
Kalehua Capital Management LLC0$00.00%−901,457−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−619,652−100.0%Sold out
Longaeva Partners L.P.0$00.00%−470,544−100.0%Sold out
Jane Street Group, LLC0$00.00%−423,536−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−311,330−100.0%Sold out
Acadian Asset Management LLC0$00.00%−290,352−100.0%Sold out
Engineers Gate Manager LP0$00.00%−141,452−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−71,880−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−61,899−100.0%Sold out
Algert Global LLC0$00.00%−48,510−100.0%Sold out
Cresset Asset Management, LLC0$00.00%−36,495−100.0%Sold out
Mariner, LLC0$00.00%−36,096−100.0%Sold out
Gotham Asset Management, LLC0$00.00%−33,606−100.0%Sold out
OP Asset Management Ltd0$00.00%−29,217−100.0%Sold out
Nomura Holdings Inc0$00.00%−25,000−100.0%Sold out
Oxford Asset Management LLP0$00.00%−22,521−100.0%Sold out
Aigen Investment Management, LP0$00.00%−22,075−100.0%Sold out
Quadrature Capital Ltd0$00.00%−21,123−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−17,516−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−15,121−100.0%Sold out
AssuredPartners Investment Advisors, LLC0$00.00%−12,062−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−15,284−100.0%Sold out
Buckingham Strategic Partners0$00.00%−11,631−100.0%Sold out
49 Wealth Management, LLC0$00.00%−11,029−100.0%Sold out
Colony Group, LLC0$00.00%−10,756−100.0%Sold out
Group One Trading, L.P.0$00.00%−6,638−100.0%Sold out
FNY Investment Advisers, LLC0$00.00%−5,000−100.0%Sold out
Advisory Services Network, LLC0$00.00%−1,697−100.0%Sold out
MAI Capital Management0$00.00%−743−100.0%Sold out
Your Advocates Ltd., LLP0$00.00%−100−100.0%Sold out
Root Financial Partners, LLC0$00.00%−93−100.0%Sold out
CWM, LLC––––Not filed
Janus Henderson Group PLC––––Not filed
Skopos Labs, Inc.––––Not filed
Red Tortoise LLC––––Not filed
Sunbelt Securities, Inc.––––Not filed