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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 13 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Relay Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
244
+22 vs. Q4 2025
Shares held
184.2M
+20.7M (+12.6%) vs. Q4 2025
Total value
$1.83B
+$448.7M (+32.4%) vs. Q4 2025
New holders
51
95 more added
Sold out
29
53 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 244 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ1 2026: $1.83B
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding RLAY in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Legal & General Group Plc82,056$816.5K0.00%−27,152−24.9%Reduced
Victory Capital Management Inc79,994$795.9K0.00%+64,978+432.7%Added
MetLife Investment Management79,024$786.3K0.00%+1,488+1.9%Added
Allspring Global Investments Holdings, LLC72,739$783.4K0.00%+7,292+11.1%Added
Mirae Asset Global ETFs Holdings Ltd.76,661$756.4K0.00%−180.0%Reduced
Vanguard Global Advisers, LLC75,079$747.0K0.00%+75,079New
Schonfeld Strategic Advisors LLC71,880$715.2K0.01%+10,027+16.2%Added
CWM, LLC69,959$696.1K0.00%+2,356+3.5%Added
Wealth Enhancement Advisory Services, LLC55,384$694.5K0.00%+7,740+16.2%Added
Profund Advisors LLC68,170$678.3K0.02%−4,416−6.1%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)66,739$664.1K0.00%+9,505+16.6%Added
Janus Henderson Group PLC65,573$652.1K0.00%+28,700+77.8%Added
J. Goldman & Co LP63,637$633.2K0.03%+51,086+407.0%Added
Prelude Capital Management, LLC61,899$615.9K0.05%+61,899New
Wellington Management Group LLP59,508$592.1K0.00%+59,508New
DekaBank Deutsche Girozentrale60,000$591.0K0.00%00.0%Unchanged
Bank of Montreal52,943$526.8K0.00%−3,511−6.2%Reduced
Franklin Resources Inc48,915$486.7K0.00%00.0%Unchanged
Algert Global LLC48,510$482.7K0.01%−97,990−66.9%Reduced
Aquatic Capital Management LLC48,120$478.8K0.01%+48,120New
Headlands Technologies LLC47,626$473.9K0.05%+47,626New
New York State Common Retirement Fund45,799$455.7K0.00%00.0%Unchanged
Barclays PLC45,267$450.4K0.00%−368,876−89.1%Reduced
Intellectus Partners, LLC42,225$420.1K0.09%−1,700−3.9%Reduced
State of New Jersey Common Pension Fund D41,464$412.6K0.00%+41,464New
LPL Financial LLC40,463$402.6K0.00%+6,319+18.5%Added
BNP Paribas Arbitrage, SA39,467$392.7K0.00%+19,463+97.3%Added
Brandywine Managers, LLC38,429$382.4K0.23%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey37,005$368.2K0.00%00.0%Unchanged
Captrust Financial Advisors36,769$365.8K0.00%+1,203+3.4%Added
Cresset Asset Management, LLC36,495$363.1K0.00%−589−1.6%Reduced
SEI Investments Co36,130$359.5K0.00%+10,500+41.0%Added
Mariner, LLC36,096$358.4K0.00%+36,096New
Valeo Financial Advisors, LLC35,714$355.4K0.01%+35,714New
Virtus Investment Advisers, Inc.33,957$337.9K0.09%+827+2.5%Added
Gotham Asset Management, LLC33,606$334.4K0.00%+33,606New
Arizona State Retirement System33,325$331.6K0.00%−206−0.6%Reduced
Skopos Labs, Inc.32,577$324.1K0.01%+5,436+20.0%Added
China Universal Asset Management Co., Ltd.31,716$315.6K0.02%+3,473+12.3%Added
Intech Investment Management LLC31,617$314.6K0.00%−21,584−40.6%Reduced
JustInvest LLC31,582$314.2K0.00%+3,995+14.5%Added
Vanguard Investments Australia, Ltd.30,117$299.7K0.00%+30,117New
Citigroup Inc29,754$296.1K0.00%−1,176−3.8%Reduced
OP Asset Management Ltd29,217$290.7K0.00%+29,217New
Pallas Capital Advisors LLC28,573$284.3K0.01%+3,453+13.7%Added
ProShare Advisors LLC28,409$282.7K0.00%−4,982−14.9%Reduced
Fiduciary Trust Co27,971$278.3K0.00%00.0%Unchanged
KLP Kapitalforvaltning AS27,200$270.6K0.00%+2,500+10.1%Added
State Board of Administration of Florida Retirement System25,807$256.8K0.00%00.0%Unchanged
Nomura Holdings Inc25,000$248.8K0.00%+25,000New
Cerity Partners LLC24,195$240.7K0.00%+3,149+15.0%Added
Virginia Retirement Systems Et Al23,200$230.8K0.00%+10,300+79.8%Added
Oxford Asset Management LLP22,521$224.1K0.09%+22,521New
Aigen Investment Management, LP22,075$219.6K0.06%+22,075New
Erste Asset Management GmbH23,100$216.0K0.00%00.0%Unchanged
Amundi21,381$212.7K0.00%+21,381New
Prudential Financial Inc21,350$212.4K0.00%+21,350New
Quantinno Capital Management LP21,188$210.8K0.00%+3,911+22.6%Added
Quadrature Capital Ltd21,123$210.2K0.00%+21,123New
Merit Financial Group, LLC21,000$208.9K0.00%+515+2.5%Added
Pictet Asset Management Holding SA19,592$194.9K0.00%+4,540+30.2%Added
E Fund Management Co., Ltd.18,933$188.4K0.01%+18,933New
Abel Hall, LLC18,237$181.5K0.04%+5,253+40.5%Added
Callan Family Office, LLC17,890$178.0K0.00%−2,641−12.9%Reduced
Y-Intercept (Hong Kong) Ltd17,516$174.3K0.00%+17,516New
Russell Investments Group, Ltd.16,840$167.6K0.00%+4,378+35.1%Added
Mercer Global Advisors Inc16,421$163.4K0.00%+3,583+27.9%Added
Persistent Asset Partners Ltd16,358$162.8K0.06%+16,358New
Teacher Retirement System of Texas15,868$157.9K0.00%−1,605−9.2%Reduced
DnB Asset Management AS15,814$157.3K0.00%+15,814New
Mirabella Financial Services LLP15,121$150.5K0.01%+15,121New
AssuredPartners Investment Advisors, LLC12,062$150.2K0.02%−4,061−25.2%Reduced
Fox Run Management, L.L.C.15,284$142.9K0.03%−44,919−74.6%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH13,869$138.0K0.00%+13,869New
Xponance, Inc.12,852$127.9K0.00%+1,850+16.8%Added
Gabelli Funds LLC12,000$119.4K0.00%+12,000New
Quadrant Capital Group LLC11,791$117.3K0.00%00.0%Unchanged
Buckingham Strategic Partners11,631$115.1K0.00%+966+9.1%Added
Duncan Williams Asset Management, LLC11,438$113.8K0.03%−325−2.8%Reduced
Ameritas Investment Partners, Inc.11,180$111.2K0.00%00.0%Unchanged
49 Wealth Management, LLC11,029$109.7K0.01%−372−3.3%Reduced
Plante Moran Financial Advisors, LLC10,836$107.8K0.01%+2,072+23.6%Added
Colony Group, LLC10,756$107.0K0.00%−6,577−37.9%Reduced
HighTower Advisors, LLC10,738$106.8K0.00%+10,738New
Tower Research Capital LLC (TRC)10,719$106.7K0.00%+10,038+1,474.0%Added
EP Wealth Advisors, LLC10,434$103.8K0.00%−2,068−16.5%Reduced
Neuberger Berman Group LLC10,048$100.0K0.00%+10,048New
Portland Investment Counsel Inc.10,000$99.5K0.03%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.9,322$92.8K0.00%+900+10.7%Added
Great West Life Assurance Co8,624$86.0K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC8,100$80.6K0.00%−800−9.0%Reduced
Group One Trading, L.P.6,638$66.0K0.00%−22,314−77.1%Reduced
Public Employees Retirement Association of Colorado5,888$59.0K0.00%00.0%Unchanged
Essential Partners LLC5,358$53.3K0.02%+12+0.2%Added
US Bancorp5,232$52.1K0.00%+101+2.0%Added
FNY Investment Advisers, LLC5,000$49.0K0.02%00.0%Unchanged
Sterling Capital Management LLC4,665$46.4K0.00%−3,451−42.5%Reduced
Farther Finance Advisors, LLC4,301$46.3K0.00%+161+3.9%Added
The PNC Financial Services Group, Inc.4,493$44.7K0.00%−113−2.5%Reduced
Smartleaf Asset Management LLC4,415$41.3K0.00%−11−0.2%Reduced