Relay Therapeutics, Inc.
RLAY- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001812364
In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Relay Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 244
- +22 vs. Q4 2025
- Shares held
- 184.2M
- +20.7M (+12.6%) vs. Q4 2025
- Total value
- $1.83B
- +$448.7M (+32.4%) vs. Q4 2025
- New holders
- 51
- 95 more added
- Sold out
- 29
- 53 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 259 | $4.58B |
| Q1 2026 | 244 | $1.83B |
| Q4 2025 | 227 | $1.47B |
| Q3 2025 | 199 | $867.4M |
| Q2 2025 | 208 | $591.8M |
| Q1 2025 | 208 | $438.1M |
| Q4 2024 | 200 | $675.8M |
| Q3 2024 | 195 | $1.16B |
| Q2 2024 | 179 | $826.8M |
| Q1 2024 | 189 | $1.10B |
| Q4 2023 | 177 | $1.40B |
| Q3 2023 | 172 | $1.10B |
| Q2 2023 | 161 | $1.64B |
| Q1 2023 | 157 | $2.16B |
| Q4 2022 | 165 | $1.91B |
| Q3 2022 | 162 | $2.76B |
| Q2 2022 | 148 | $2.02B |
| Q1 2022 | 140 | $3.38B |
| Q4 2021 | 131 | $3.41B |
| Q3 2021 | 132 | $2.89B |
| Q2 2021 | 125 | $3.26B |
| Q1 2021 | 137 | $2.96B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Congress Asset Management Co | 618,938 | $6.16M | 0.04% | +204,771+49.4% | Added |
| Qube Research & Technologies Ltd | 619,652 | $6.17M | 0.01% | +619,652 | New |
| Arrowstreet Capital, Limited Partnership | 668,289 | $6.65M | 0.00% | +668,289 | New |
| Invesco Ltd. | 669,874 | $6.67M | 0.00% | −195,607−22.6% | Reduced |
| Squadron Capital Management LLC | 672,500 | $6.69M | 2.68% | +672,500 | New |
| Renaissance Technologies LLC | 673,599 | $6.70M | 0.01% | +25,700+4.0% | Added |
| Woodline Partners LP | 679,342 | $6.76M | 0.03% | +2270.0% | Added |
| Logos Global Management LP | 750,000 | $7.46M | 0.38% | +750,000 | New |
| Panagora Asset Management Inc | 818,041 | $8.14M | 0.03% | +818,041 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 837,038 | $8.33M | 0.02% | +447,475+114.9% | Added |
| Vanguard Fiduciary Trust Co | 900,546 | $8.96M | 0.00% | +900,546 | New |
| Kalehua Capital Management LLC | 901,457 | $8.97M | 6.35% | 00.0% | Unchanged |
| Marshall Wace, LLP | 941,825 | $9.37M | 0.01% | +941,825 | New |
| Foresite Capital Management IV, LLC | 1,000,000 | $9.95M | 4.20% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 1,111,891 | $11.1M | 0.00% | −24,811−2.2% | Reduced |
| Baker Bros. Advisors LP | 1,160,117 | $11.5M | 0.07% | 00.0% | Unchanged |
| AQR Capital Management LLC | 1,290,032 | $12.8M | 0.01% | +126,908+10.9% | Added |
| Two Sigma Investments, LP | 1,369,149 | $13.6M | 0.01% | −191,116−12.2% | Reduced |
| Kynam Capital Management, LP | 1,424,259 | $14.2M | 0.90% | 00.0% | Unchanged |
| Morgan Stanley | 1,432,003 | $14.2M | 0.00% | −586,461−29.1% | Reduced |
| Alphabet Inc. | 1,564,173 | $15.6M | 0.39% | −4,580−0.3% | Reduced |
| Northern Trust Corp | 1,675,387 | $16.7M | 0.00% | +536,699+47.1% | Added |
| Vanguard Portfolio Management LLC | 1,863,565 | $18.5M | 0.00% | +1,863,565 | New |
| EcoR1 Capital, LLC | 1,904,762 | $19.0M | 0.81% | +1,904,762 | New |
| Price T Rowe Associates Inc | 1,924,938 | $19.2M | 0.00% | +279,535+17.0% | Added |
| Bank of America Corp | 1,937,695 | $19.3M | 0.00% | +896,746+86.1% | Added |
| MPM Oncology Impact Management LP | 2,359,586 | $23.5M | 1.81% | +127,135+5.7% | Added |
| Goldman Sachs Group Inc | 2,541,861 | $25.3M | 0.00% | +682,227+36.7% | Added |
| Adage Capital Partners GP, L.L.C. | 2,590,000 | $25.8M | 0.04% | +2,090,000+418.0% | Added |
| Dimensional Fund Advisors LP | 2,940,536 | $29.2M | 0.01% | +460,186+18.6% | Added |
| Spruce Street Capital LP | 2,984,125 | $29.7M | 7.14% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 3,039,179 | $30.2M | 0.06% | +939,267+44.7% | Added |
| Geode Capital Management, LLC | 3,510,636 | $34.9M | 0.00% | +101,273+3.0% | Added |
| FMR LLC | 3,695,431 | $36.8M | 0.00% | +3,533,209+2,178.0% | Added |
| TCG Crossover Management, LLC | 4,273,356 | $42.5M | 1.22% | +1,053,170+32.7% | Added |
| Nextech Invest, Ltd. | 5,526,506 | $55.0M | 3.87% | +825,000+17.5% | Added |
| State Street Corp | 6,233,545 | $62.0M | 0.00% | −192,566−3.0% | Reduced |
| Vanguard Capital Management LLC | 7,387,465 | $73.5M | 0.00% | +7,387,465 | New |
| Bellevue Group AG | 7,795,242 | $77.6M | 1.85% | −550,122−6.6% | Reduced |
| Perceptive Advisors LLC | 9,751,141 | $97.0M | 1.92% | +7,847,896+412.3% | Added |
| BlackRock, Inc. | 12,975,299 | $129.1M | 0.00% | −253,203−1.9% | Reduced |
| Casdin Capital, LLC | 14,418,574 | $143.5M | 10.86% | +1,415,000+10.9% | Added |
| Commodore Capital LP | 17,000,000 | $169.2M | 9.79% | 00.0% | Unchanged |
| SB Investment Advisers (UK) Ltd | 27,904,963 | $277.7M | 3.59% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −13,859,172−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −1,289,800−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −1,141,880−100.0% | Sold out |
| Allianz Asset Management GmbH | 0 | $0 | 0.00% | −560,298−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −398,167−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −113,230−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −84,163−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −82,559−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −66,587−100.0% | Sold out |
| Private Capital Advisors, Inc. | 0 | $0 | 0.00% | −59,311−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −54,993−100.0% | Sold out |
| Mayport, LLC | 0 | $0 | 0.00% | −49,681−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −42,000−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −39,447−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −33,236−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −32,658−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −30,645−100.0% | Sold out |
| VARCOV Co. | 0 | $0 | 0.00% | −29,289−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −28,906−100.0% | Sold out |
| Blueshift Asset Management, LLC | 0 | $0 | 0.00% | −26,814−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −23,126−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −16,000−100.0% | Sold out |
| Opal Capital LLC | 0 | $0 | 0.00% | −11,401−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −10,127−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −4,424−100.0% | Sold out |
| Torren Management, LLC | 0 | $0 | 0.00% | −3,544−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −486−100.0% | Sold out |
| SageView Advisory Group, LLC | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Norges Bank | – | – | – | – | Not filed |
| CIBC Private Wealth Group, LLC | – | – | – | – | Not filed |
| Comerica Bank | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |