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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 13 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Relay Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
208
+12 vs. Q4 2024
Shares held
167.3M
+8.03M (+5.0%) vs. Q4 2024
Total value
$438.1M
−$218.3M (−33.3%) vs. Q4 2024
New holders
36
73 more added
Sold out
24
59 more reduced

4 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 208 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ1 2025: $438.1M
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding RLAY in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bellevue Group AG7,377,292$19.3M0.43%00.0%Unchanged
Tang Capital Management LLC8,068,058$21.1M1.17%00.0%Unchanged
Casdin Capital, LLC9,098,574$23.8M1.95%+150,000+1.7%Added
Point72 Asset Management, L.P.10,827,067$28.4M0.08%+9,234,314+579.8%Added
Vanguard Group Inc12,105,420$31.7M0.00%−2,924,789−19.5%Reduced
BlackRock, Inc.14,478,798$37.9M0.00%−195,464−1.3%Reduced
SB Investment Advisers (UK) Ltd27,904,963$73.1M0.67%00.0%Unchanged
DekaBank Deutsche Girozentrale68,937––+8,937+14.9%Added
Adage Capital Partners GP, L.L.C.0$00.00%−1,400,000−100.0%Sold out
Exome Asset Management LLC0$00.00%−1,083,487−100.0%Sold out
Boxer Capital Management, LLC0$00.00%−536,132−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−317,211−100.0%Sold out
BIT Capital GmbH0$00.00%−284,508−100.0%Sold out
Jump Financial, LLC0$00.00%−138,226−100.0%Sold out
First Trust Advisors LP0$00.00%−89,949−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−87,863−100.0%Sold out
Nebula Research & Development LLC0$00.00%−86,641−100.0%Sold out
Aristides Capital LLC0$00.00%−43,400−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−31,569−100.0%Sold out
Savant Capital, LLC0$00.00%−29,088−100.0%Sold out
Marshall Wace, LLP0$00.00%−27,768−100.0%Sold out
Syon Capital LLC0$00.00%−22,157−100.0%Sold out
Virtu Financial LLC0$00.00%−15,046−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−14,873−100.0%Sold out
Atom Investors LP0$00.00%−11,765−100.0%Sold out
Twinbeech Capital LP0$00.00%−10,204−100.0%Sold out
Stifel Financial Corp0$00.00%−10,200−100.0%Sold out
Wingate Wealth Advisors, Inc.0$00.00%−5,000−100.0%Sold out
Group One Trading, L.P.0$00.00%−4,774−100.0%Sold out
R Squared Ltd0$00.00%−1,180−100.0%Sold out
Ancora Advisors, LLC0$00.00%−110−100.0%Sold out
WealthTrak Capital Management LLC0$00.00%−30−100.0%Sold out
Nextech Invest AG––––Not filed
Nuveen Asset Management, LLC––––Not filed
Fernwood Investment Management, LLC––––Not filed
Global Retirement Partners, LLC––––Not filed