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Ultragenyx Pharmaceutical Inc.

RARE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001515673

In the last 90 days, Ultragenyx Pharmaceutical Inc. insiders filed 0 open-market purchases and 5 sales; 311 institutions reported holding it in 13F filings for Q2 2026, worth $3.55B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Ultragenyx Pharmaceutical Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
288
−8 vs. Q3 2025
Shares held
93.9M
−797.2K (−0.8%) vs. Q3 2025
Total value
$2.16B
−$688.2M (−24.1%) vs. Q3 2025
New holders
57
111 more added
Sold out
65
91 more reduced

7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RARE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 288 institutions
Q1 2021: 255 institutionsQ2 2021: 242 institutionsQ3 2021: 223 institutionsQ4 2021: 235 institutionsQ1 2022: 240 institutionsQ2 2022: 225 institutionsQ3 2022: 233 institutionsQ4 2022: 228 institutionsQ1 2023: 230 institutionsQ2 2023: 243 institutionsQ3 2023: 221 institutionsQ4 2023: 237 institutionsQ1 2024: 270 institutionsQ2 2024: 275 institutionsQ3 2024: 302 institutionsQ4 2024: 314 institutionsQ1 2025: 301 institutionsQ2 2025: 311 institutionsQ3 2025: 303 institutionsQ4 2025: 288 institutionsQ1 2026: 298 institutionsQ2 2026: 311 institutions
Value heldQ4 2025: $2.16B
Q1 2021: $7.73BQ2 2021: $6.24BQ3 2021: $6.01BQ4 2021: $5.69BQ1 2022: $4.87BQ2 2022: $4.03BQ3 2022: $2.81BQ4 2022: $3.15BQ1 2023: $2.76BQ2 2023: $3.21BQ3 2023: $2.52BQ4 2023: $3.84BQ1 2024: $3.73BQ2 2024: $3.63BQ3 2024: $4.83BQ4 2024: $3.68BQ1 2025: $3.25BQ2 2025: $3.42BQ3 2025: $2.87BQ4 2025: $2.16BQ1 2026: $2.05BQ2 2026: $3.55B
Institutions holding RARE and their total value by quarter
QuarterHoldersValue
Q2 2026311$3.55B
Q1 2026298$2.05B
Q4 2025288$2.16B
Q3 2025303$2.87B
Q2 2025311$3.42B
Q1 2025301$3.25B
Q4 2024314$3.68B
Q3 2024302$4.83B
Q2 2024275$3.63B
Q1 2024270$3.73B
Q4 2023237$3.84B
Q3 2023221$2.52B
Q2 2023243$3.21B
Q1 2023230$2.76B
Q4 2022228$3.15B
Q3 2022233$2.81B
Q2 2022225$4.03B
Q1 2022240$4.87B
Q4 2021235$5.69B
Q3 2021223$6.01B
Q2 2021242$6.24B
Q1 2021255$7.73B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Ultragenyx Pharmaceutical Inc.; share changes are against Q3 2025.

Institutions holding RARE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Clearbridge Investments, LLC0$00.00%−155,752−100.0%Sold out
Gilder Gagnon Howe & Co LLC0$00.00%−121,941−100.0%Sold out
Rhenman & Partners Asset Management AB0$00.00%−119,400−100.0%Sold out
Amundi0$00.00%−99,161−100.0%Sold out
Thornburg Investment Management Inc0$00.00%−69,248−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−67,834−100.0%Sold out
Artia Global Partners LP0$00.00%−64,502−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−61,875−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−46,269−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−31,334−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−23,759−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−22,723−100.0%Sold out
Stonepine Capital Management, LLC0$00.00%−20,000−100.0%Sold out
Concentric Capital Strategies, LP0$00.00%−19,736−100.0%Sold out
Freestone Grove Partners LP0$00.00%−18,639−100.0%Sold out
Silvant Capital Management LLC0$00.00%−18,607−100.0%Sold out
Woodstock Corp0$00.00%−18,114−100.0%Sold out
Polygon Management Ltd.0$00.00%−17,718−100.0%Sold out
DnB Asset Management AS0$00.00%−17,479−100.0%Sold out
Pier 88 Investment Partners LLC0$00.00%−14,170−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−13,100−100.0%Sold out
Virtu Financial LLC0$00.00%−12,861−100.0%Sold out
Toroso Investments, LLC0$00.00%−11,947−100.0%Sold out
DRW Securities, LLC0$00.00%−12,266−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−11,466−100.0%Sold out
Vontobel Holding Ltd.0$00.00%−10,935−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−10,875−100.0%Sold out
American Century Companies Inc0$00.00%−10,054−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−9,385−100.0%Sold out
Diadema Partners LP0$00.00%−9,189−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−9,000−100.0%Sold out
Lecap Asset Management Ltd0$00.00%−8,515−100.0%Sold out
Oppenheimer Asset Management Inc.0$00.00%−8,142−100.0%Sold out
Everence Capital Management Inc0$00.00%−7,441−100.0%Sold out
Farallon Capital Management, L.L.C.0$00.00%−7,000−100.0%Sold out
denkapparat Operations GmbH0$00.00%−6,892−100.0%Sold out
Quantbot Technologies LP0$00.00%−6,251−100.0%Sold out
Acadian Asset Management LLC0$00.00%−4,463−100.0%Sold out
Tortoise Investment Management, LLC0$00.00%−845−100.0%Sold out
Manchester Capital Management LLC0$00.00%−385−100.0%Sold out
St Germain D J Co Inc0$00.00%−300−100.0%Sold out
Caldwell Sutter Capital, Inc.0$00.00%−160−100.0%Sold out
NBC Securities, Inc.0$00.00%−159−100.0%Sold out
Mather Group, LLC.0$00.00%−110−100.0%Sold out
National Bank of Canada0$00.00%−104−100.0%Sold out
GPS Wealth Strategies Group, LLC0$00.00%−100−100.0%Sold out
Stone House Investment Management, LLC0$00.00%−81−100.0%Sold out
MAI Capital Management0$00.00%−47−100.0%Sold out
Kilter Group LLC0$00.00%−29−100.0%Sold out
Advisory Services Network, LLC0$00.00%−20−100.0%Sold out
Rise Advisors, LLC0$00.00%−17−100.0%Sold out
CIBC Private Wealth Group, LLC0$00.00%−5−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−4−100.0%Sold out
AXA Investment Managers S.A.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
EFG Asset Management (North America) Corp.––––Not filed
Wolverine Trading, LLC––––Not filed
Point72 Hong Kong Ltd––––Not filed
Point72 (DIFC) Ltd––––Not filed
Shell Asset Management Co––––Not filed