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Ultragenyx Pharmaceutical Inc.

RARE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001515673

In the last 90 days, Ultragenyx Pharmaceutical Inc. insiders filed 0 open-market purchases and 5 sales; 311 institutions reported holding it in 13F filings for Q2 2026, worth $3.55B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Ultragenyx Pharmaceutical Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
288
−8 vs. Q3 2025
Shares held
93.9M
−797.2K (−0.8%) vs. Q3 2025
Total value
$2.16B
−$688.2M (−24.1%) vs. Q3 2025
New holders
57
111 more added
Sold out
65
91 more reduced

7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RARE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 288 institutions
Q1 2021: 255 institutionsQ2 2021: 242 institutionsQ3 2021: 223 institutionsQ4 2021: 235 institutionsQ1 2022: 240 institutionsQ2 2022: 225 institutionsQ3 2022: 233 institutionsQ4 2022: 228 institutionsQ1 2023: 230 institutionsQ2 2023: 243 institutionsQ3 2023: 221 institutionsQ4 2023: 237 institutionsQ1 2024: 270 institutionsQ2 2024: 275 institutionsQ3 2024: 302 institutionsQ4 2024: 314 institutionsQ1 2025: 301 institutionsQ2 2025: 311 institutionsQ3 2025: 303 institutionsQ4 2025: 288 institutionsQ1 2026: 298 institutionsQ2 2026: 311 institutions
Value heldQ4 2025: $2.16B
Q1 2021: $7.73BQ2 2021: $6.24BQ3 2021: $6.01BQ4 2021: $5.69BQ1 2022: $4.87BQ2 2022: $4.03BQ3 2022: $2.81BQ4 2022: $3.15BQ1 2023: $2.76BQ2 2023: $3.21BQ3 2023: $2.52BQ4 2023: $3.84BQ1 2024: $3.73BQ2 2024: $3.63BQ3 2024: $4.83BQ4 2024: $3.68BQ1 2025: $3.25BQ2 2025: $3.42BQ3 2025: $2.87BQ4 2025: $2.16BQ1 2026: $2.05BQ2 2026: $3.55B
Institutions holding RARE and their total value by quarter
QuarterHoldersValue
Q2 2026311$3.55B
Q1 2026298$2.05B
Q4 2025288$2.16B
Q3 2025303$2.87B
Q2 2025311$3.42B
Q1 2025301$3.25B
Q4 2024314$3.68B
Q3 2024302$4.83B
Q2 2024275$3.63B
Q1 2024270$3.73B
Q4 2023237$3.84B
Q3 2023221$2.52B
Q2 2023243$3.21B
Q1 2023230$2.76B
Q4 2022228$3.15B
Q3 2022233$2.81B
Q2 2022225$4.03B
Q1 2022240$4.87B
Q4 2021235$5.69B
Q3 2021223$6.01B
Q2 2021242$6.24B
Q1 2021255$7.73B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Ultragenyx Pharmaceutical Inc.; share changes are against Q3 2025.

Institutions holding RARE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Erste Asset Management GmbH15,010$296.0K0.00%00.0%Unchanged
CWM, LLC13,125$302.0K0.00%+9,028+220.4%Added
Walleye Trading LLC13,167$302.8K0.00%+4,911+59.5%Added
Oak Ridge Investments LLC13,394$308.1K0.02%−3,232−19.4%Reduced
Tudor Investment Corp Et Al13,416$308.6K0.00%−45,862−77.4%Reduced
Voleon Capital Management LP13,956$321.0K0.01%+13,956New
Mercer Global Advisors Inc13,965$321.2K0.00%+2,036+17.1%Added
Universal- Beteiligungs- und Servicegesellschaft mbH14,094$322.9K0.00%−77,300−84.6%Reduced
Summit Trail Advisors, LLC14,339$329.8K0.01%+5,497+62.2%Added
Xponance, Inc.14,390$331.0K0.00%+896+6.6%Added
Cerity Partners LLC15,678$360.6K0.00%+15,678New
China Universal Asset Management Co., Ltd.15,721$361.6K0.03%−1,172−6.9%Reduced
DAFNA Capital Management LLC16,000$368.0K0.09%+16,000New
Fiduciary Trust Co16,268$374.2K0.00%+3,152+24.0%Added
First Trust Advisors LP16,642$382.8K0.00%−19,692−54.2%Reduced
KLP Kapitalforvaltning AS18,500$425.5K0.00%+800+4.5%Added
Virtus Investment Advisers, Inc.18,862$433.8K0.12%+7,551+66.8%Added
Stifel Financial Corp18,997$436.9K0.00%−6,461−25.4%Reduced
Inceptionr LLC19,714$453.4K0.13%+19,714New
Raymond James Financial Inc19,851$456.6K0.00%−4,706−19.2%Reduced
Victory Capital Management Inc19,907$457.9K0.00%−278,984−93.3%Reduced
Voya Investment Management LLC19,934$458.5K0.00%−679−3.3%Reduced
Knott David M Jr20,006$460.1K0.21%−31,994−61.5%Reduced
Envestnet Asset Management Inc20,112$462.6K0.00%−4,921−19.7%Reduced
Virginia Retirement Systems Et Al20,119$462.7K0.00%+6,350+46.1%Added
Oxford Asset Management LLP20,475$470.9K0.17%+20,475New
Natixis Advisors, L.P.21,077$485.0K0.00%+1,498+7.7%Added
LMR Partners LLP21,674$498.5K0.00%+21,674New
Odyssean, LLC22,230$511.3K0.37%+22,230New
Group One Trading, L.P.23,208$533.8K0.02%+23,208New
IMC-Chicago, LLC23,397$538.1K0.01%+23,397New
Arizona State Retirement System23,969$551.3K0.00%−1,207−4.8%Reduced
S&CO Inc25,255$580.0K0.04%00.0%Unchanged
Alliancebernstein L.P.27,285$627.6K0.00%+577+2.2%Added
Public Employees Retirement System of Ohio27,747$638.2K0.00%−312−1.1%Reduced
Headlands Technologies LLC28,207$648.8K0.05%+2,778+10.9%Added
Zurcher Kantonalbank (Zurich Cantonalbank)28,240$649.5K0.00%+1,875+7.1%Added
HSBC Holdings PLC29,679$662.7K0.00%−47,206−61.4%Reduced
State of New Jersey Common Pension Fund D29,604$680.9K0.00%−42,451−58.9%Reduced
Toronto Dominion Bank31,700$729.1K0.00%+31,700New
Superstring Capital Management LP31,738$730.0K0.39%+31,738New
SG Americas Securities, LLC32,204$741.0K0.00%−93,225−74.3%Reduced
Handelsbanken Fonder AB33,523$771.0K0.00%+6,400+23.6%Added
New York State Common Retirement Fund34,024$782.6K0.00%−1,322−3.7%Reduced
Pathstone Holdings, LLC34,339$789.8K0.00%+413+1.2%Added
Walleye Capital LLC36,484$839.1K0.00%−31,449−46.3%Reduced
Janus Henderson Group PLC36,543$840.5K0.00%00.0%Unchanged
Alberta Investment Management Corp38,400$883.2K0.01%+38,400New
Treasurer of the State of North Carolina38,620$888.0K0.00%−1,763−4.4%Reduced
Police & Firemen's Retirement System of New Jersey39,398$906.2K0.01%+54+0.1%Added
Wedge Capital Management L L P42,302$972.9K0.02%−877−2.0%Reduced
Scientech Research LLC48,032$1.10M0.69%+16,727+53.4%Added
Guggenheim Capital LLC49,137$1.13M0.01%+2,061+4.4%Added
Quantinno Capital Management LP49,750$1.14M0.00%+11,245+29.2%Added
Ishara Investments LP50,000$1.15M1.34%+50,000New
Flax Pond Capital, LLC56,238$1.29M0.96%+56,238New
Profund Advisors LLC56,624$1.30M0.04%+24,360+75.5%Added
Nordea Investment Management AB58,838$1.32M0.00%−6,899−10.5%Reduced
State of Wisconsin Investment Board58,657$1.35M0.00%−22,281−27.5%Reduced
Entropy Technologies, LP60,641$1.39M0.08%+40,577+202.2%Added
Fideuram - Intesa Sanpaolo Private Banking S.P.A.61,329$1.41M0.05%+61,329New
Birchview Capital, LP62,000$1.43M0.83%+40,000+181.8%Added
Parkman Healthcare Partners LLC62,030$1.43M0.14%−6,606−9.6%Reduced
Hennion & Walsh Asset Management, Inc.62,173$1.43M0.05%−11,621−15.7%Reduced
Wells Fargo & Company63,563$1.46M0.00%+38,615+154.8%Added
Quadrature Capital Ltd66,001$1.52M0.02%+66,001New
Mirae Asset Global ETFs Holdings Ltd.66,175$1.52M0.00%+3,572+5.7%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main67,339$1.55M0.00%−213,127−76.0%Reduced
Citigroup Inc69,511$1.60M0.00%+43,322+165.4%Added
Marshall Wace, LLP72,168$1.66M0.00%−73,926−50.6%Reduced
Motley Fool Asset Management LLC72,448$1.67M0.06%−10,152−12.3%Reduced
F/M Investments LLC73,484$1.69M0.06%+11,731+19.0%Added
Affinity Asset Advisors, LLC75,000$1.73M0.12%+75,000New
Engineers Gate Manager LP76,702$1.76M0.02%+43,579+131.6%Added
Man Group plc78,371$1.80M0.00%+71,219+995.8%Added
TD Asset Management Inc81,964$1.89M0.00%−15,034−15.5%Reduced
Sofinnova Investments, Inc.83,300$1.92M0.08%+83,300New
California State Teachers Retirement System83,337$1.92M0.00%+2,447+3.0%Added
Aquatic Capital Management LLC87,464$2.01M0.06%−103,994−54.3%Reduced
State Board of Administration of Florida Retirement System96,836$2.23M0.00%+4,070+4.4%Added
Worldquant Millennium Advisors LLC96,908$2.23M0.01%+96,908New
Edgestream Partners, L.P.99,873$2.30M0.06%+99,873New
Crestwood Advisors Group LLC100,131$2.30M0.04%−513−0.5%Reduced
Twinbeech Capital LP100,152$2.30M0.16%+100,152New
Rhumbline Advisers101,826$2.34M0.00%−3,905−3.7%Reduced
Brevan Howard Capital Management LP107,903$2.42M0.05%+40,868+61.0%Added
Pinnacle Associates Ltd111,560$2.57M0.03%−3,285−2.9%Reduced
Jump Financial, LLC115,928$2.67M0.03%+58,460+101.7%Added
Comerica Bank118,422$2.72M0.01%+34,711+41.5%Added
XTX Topco Ltd119,996$2.76M0.07%+105,622+734.8%Added
Emerald Mutual Fund Advisers Trust120,505$2.77M0.14%−122,297−50.4%Reduced
Caitong International Asset Management Co., Ltd122,854$2.83M0.69%+122,843+1,116,754.5%Added
DekaBank Deutsche Girozentrale57,000$2.90M0.01%00.0%Unchanged
B Group, Inc.135,000$3.10M2.30%00.0%Unchanged
ExodusPoint Capital Management, LP137,392$3.16M0.04%+30,817+28.9%Added
Sr One Capital Management, LP137,753$3.17M0.45%+137,753New
Krensavage Asset Management, LLC149,634$3.44M1.22%+149,634New
Capital Fund Management S.A.150,201$3.45M0.03%−26,860−15.2%Reduced
Susquehanna International Group, LLP152,316$3.50M0.00%−81,810−34.9%Reduced
SEI Investments Co153,726$3.54M0.00%−36,736−19.3%Reduced