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Pyxis Oncology, Inc.

PYXS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001782223

In the last 90 days, Pyxis Oncology, Inc. insiders filed 1 open-market purchase and 0 sales; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.

Four kinds of short-selling data, each measuring something different:

  • Short interest: shares sold short and not yet bought back, as of a settlement date. FINRA publishes it twice a month, about eight business days after the settlement date.
  • Daily short volume: shares sold short each day in off-exchange trades reported to FINRA. It counts trades, not open positions, and is published the next day.
  • Fails-to-deliver: shares not delivered by the settlement date. The SEC publishes them twice a month, about two weeks late.
  • ATS (dark pool) volume: weekly volume on alternative trading systems and other off-exchange venues. FINRA publishes it two to four weeks after the week.

More in the glossary.

Short interest

Shares sold short and not yet bought back, from FINRA, on every settlement date in the last two years.

Short interest
4.53M
Shares, settlement Oct 30, 2026
Change
+179.3K
+4.1% vs. Oct 15, 2026
Days to cover
5.82
Short interest ÷ average daily volume
Average daily volume
777.6K
Shares, as reported by FINRA
Short interest by settlement date
Oct 31, 2024: 5,855,879 sharesNov 15, 2024: 5,841,190 sharesNov 29, 2024: 6,083,882 sharesDec 13, 2024: 6,400,100 sharesDec 31, 2024: 7,340,965 sharesJan 15, 2025: 7,424,946 sharesJan 31, 2025: 7,003,439 sharesFeb 14, 2025: 6,876,231 sharesFeb 28, 2025: 7,008,856 sharesMar 14, 2025: 6,924,016 sharesMar 31, 2025: 7,336,969 sharesApr 15, 2025: 7,131,225 sharesApr 30, 2025: 7,233,818 sharesMay 15, 2025: 7,048,248 sharesMay 30, 2025: 6,472,521 sharesJun 13, 2025: 6,180,200 sharesJun 30, 2025: 5,064,919 sharesJul 15, 2025: 4,781,095 sharesJul 31, 2025: 4,695,721 sharesAug 15, 2025: 5,032,348 sharesAug 29, 2025: 4,334,176 sharesSep 15, 2025: 4,359,697 sharesSep 30, 2025: 4,131,340 sharesOct 15, 2025: 4,250,799 sharesOct 31, 2025: 4,361,521 sharesNov 14, 2025: 4,541,093 sharesNov 28, 2025: 4,523,744 sharesDec 15, 2025: 1,933,041 sharesDec 31, 2025: 1,733,403 sharesJan 15, 2026: 2,307,831 sharesJan 30, 2026: 2,386,094 sharesFeb 13, 2026: 2,442,905 sharesFeb 27, 2026: 2,525,155 sharesMar 13, 2026: 2,490,249 sharesMar 31, 2026: 2,660,931 sharesApr 15, 2026: 2,269,065 sharesApr 30, 2026: 1,986,201 sharesMay 15, 2026: 1,809,793 sharesMay 29, 2026: 1,741,743 sharesJun 15, 2026: 2,015,710 sharesJun 30, 2026: 2,289,798 sharesJul 15, 2026: 3,253,653 sharesJul 31, 2026: 4,172,154 sharesAug 14, 2026: 4,425,542 sharesAug 31, 2026: 3,968,105 sharesSep 15, 2026: 4,678,522 sharesSep 30, 2026: 4,886,652 sharesOct 15, 2026: 4,345,953 sharesOct 30, 2026: 4,525,205 shares
Short interest in PYXS by settlement date
Settlement dateShort interestChangeChange %Avg. daily volumeDays to cover
Oct 30, 20264.53M+179.3K+4.1%777.6K5.82
Oct 15, 20264.35M−540.7K−11.1%1.25M3.47
Sep 30, 20264.89M+208.1K+4.5%1.21M4.05
Sep 15, 20264.68M+710.4K+17.9%1.28M3.65
Aug 31, 20263.97M−457.4K−10.3%570.0K6.96
Aug 14, 20264.43M+253.4K+6.1%2.22M1.99
Jul 31, 20264.17M+918.5K+28.2%996.5K4.19
Jul 15, 20263.25M+963.9K+42.1%1.05M3.11
Jun 30, 20262.29M+274.1K+13.6%1.84M1.25
Jun 15, 20262.02M+274.0K+15.7%415.5K4.85
May 29, 20261.74M−68.0K−3.8%607.7K2.87
May 15, 20261.81M−176.4K−8.9%856.0K2.11
Apr 30, 20261.99M−282.9K−12.5%360.8K5.51
Apr 15, 20262.27M−391.9K−14.7%402.6K5.64
Mar 31, 20262.66M+170.7K+6.9%360.9K7.37
Mar 13, 20262.49M−34.9K−1.4%323.4K7.70
Feb 27, 20262.53M+82.3K+3.4%256.3K9.85
Feb 13, 20262.44M+56.8K+2.4%645.8K3.78
Jan 30, 20262.39M+78.3K+3.4%605.7K3.94
Jan 15, 20262.31M+574.4K+33.1%1.93M1.20
Dec 31, 20251.73M−199.6K−10.3%2.89M1.00
Dec 15, 20251.93M−2.59M−57.3%645.3K3.00
Nov 28, 20254.52M−17.3K−0.4%590.6K7.66
Nov 14, 20254.54M+179.6K+4.1%947.9K4.79
Oct 31, 20254.36M+110.7K+2.6%559.7K7.79
Oct 15, 20254.25M+119.5K+2.9%1.09M3.91
Sep 30, 20254.13M−228.4K−5.2%686.7K6.02
Sep 15, 20254.36M+25.5K+0.6%1.05M4.16
Aug 29, 20254.33M−698.2K−13.9%570.3K7.60
Aug 15, 20255.03M+336.6K+7.2%333.4K15.10
Jul 31, 20254.70M−85.4K−1.8%394.8K11.89
Jul 15, 20254.78M−283.8K−5.6%440.1K10.86
Jun 30, 20255.06M−1.12M−18.1%1.01M5.04
Jun 13, 20256.18M−292.3K−4.5%454.1K13.61
May 30, 20256.47M−575.7K−8.2%348.5K18.57
May 15, 20257.05M−185.6K−2.6%521.3K13.52
Apr 30, 20257.23M+102.6K+1.4%584.3K12.38
Apr 15, 20257.13M−205.7K−2.8%465.5K15.32
Mar 31, 20257.34M+413.0K+6.0%478.1K15.35
Mar 14, 20256.92M−84.8K−1.2%485.1K14.27
Feb 28, 20257.01M+132.6K+1.9%861.9K8.13
Feb 14, 20256.88M−127.2K−1.8%653.3K10.53
Jan 31, 20257.00M−421.5K−5.7%463.1K15.12
Jan 15, 20257.42M+84.0K+1.1%713.1K10.41
Dec 31, 20247.34M+940.9K+14.7%918.8K7.99
Dec 13, 20246.40M+316.2K+5.2%1.40M4.57
Nov 29, 20246.08M+242.7K+4.2%3.88M1.57
Nov 15, 20245.84M−14.7K−0.3%741.4K7.88
Oct 31, 20245.86M+946.5K+19.3%681.9K8.59

Fails-to-deliver

Shares that weren't delivered by the settlement date, from the SEC, for the last 30 dates with fails. The price is the previous day's closing price published by the SEC.

Fails-to-deliver in PYXS by settlement date
Settlement dateSharesPriceValue
Sep 30, 202631$2.90$89.9
Sep 24, 20267,469$3.22$24.1K
Sep 23, 202685$3.36$285.6
Sep 17, 202646,846$3.34$156.5K
Sep 11, 202615,104$3.27$49.4K
Sep 10, 202617,704$3.38$59.8K
Sep 9, 202617,768$3.89$69.1K
Sep 8, 202612,805$3.89$49.8K
Sep 2, 20261,480$3.44$5.09K
Sep 1, 202696$3.24$311.04
Aug 31, 20263$3.23$9.69
Aug 27, 202667$3.34$223.78
Aug 20, 20261$3.37$3.37
Aug 19, 20261$2.99$2.99
Aug 12, 2026179$2.83$506.57
Aug 6, 20264$3.13$12.52
Aug 5, 20262$3.16$6.32
Aug 4, 20261,528$3.04$4.65K
Aug 3, 202688$2.65$233.2
Jul 31, 20264,038$2.87$11.6K
Jul 30, 20269,589$2.92$28.0K
Jul 28, 20265$2.91$14.55
Jul 27, 20267,246$2.61$18.9K
Jul 17, 20263,244$2.23$7.23K
Jul 13, 202614,206$2.67$37.9K
Jul 8, 202661,003$3.07$187.3K
Jul 6, 202670$2.63$184.1
Jul 1, 202614,020$3.01$42.2K
Jun 30, 20264,274$2.86$12.2K
Jun 29, 202639,484$2.77$109.4K

Daily short volume

Off-exchange short-sale volume, not short interest: shares sold short each day in trades reported to FINRA, for the last 30 trading days.

The short volume ratio isn't a sentiment gauge: market makers sell short to fill buy orders and to hedge, so short sales are usually about half of off-exchange volume.

Off-exchange short volume in PYXS by trade date
Trade dateShort volumeShort exemptOff-exchange volumeShort volume ratio
Nov 11, 2026252,431500331,86076.1%
Nov 10, 2026113,7050205,71655.3%
Nov 9, 2026255,5200379,99467.2%
Nov 6, 2026122,99447236,14852.1%
Nov 5, 2026206,024665530,78838.8%
Nov 4, 2026182,1540372,10749.0%
Nov 3, 2026215,3011,250341,42663.1%
Nov 2, 2026324,1410437,36874.1%
Oct 30, 2026145,7531,073301,93748.3%
Oct 29, 2026129,97395335,08438.8%
Oct 28, 2026184,2390337,28654.6%
Oct 27, 2026237,3810596,14539.8%
Oct 26, 2026167,1840294,20656.8%
Oct 23, 2026173,2320356,39448.6%
Oct 22, 2026148,48314282,60252.5%
Oct 21, 2026135,2340262,24951.6%
Oct 20, 2026224,878900416,24154.0%
Oct 19, 2026243,1071,500459,64252.9%
Oct 16, 2026231,119100413,71455.9%
Oct 15, 2026139,4500290,64748.0%
Oct 14, 2026164,449170493,25333.3%
Oct 13, 2026175,3953,500416,63742.1%
Oct 12, 2026163,5024,728253,00264.6%
Oct 9, 2026183,5560413,95044.3%
Oct 8, 2026224,8830427,42852.6%
Oct 7, 2026276,22743,006414,76766.6%
Oct 6, 2026371,87422,256814,67545.6%
Oct 5, 2026357,3231,020568,81962.8%
Oct 2, 2026594,4116,7431,053,16256.4%
Oct 1, 20261,104,67597,0311,761,91862.7%

ATS (dark pool) volume

Weekly volume on alternative trading systems (ATS) and other off-exchange (OTC) venues, from FINRA, for the last 12 weeks. ATS share is ATS volume ÷ (ATS + OTC volume), not a share of all trading.

Weekly ATS and OTC volume in PYXS
Week ofTierATS sharesATS tradesOther OTC sharesOther OTC tradesATS share
Oct 5, 2026T2939,87712,5421,876,3093,89033.4%
Sep 28, 2026T22,424,53019,8634,171,8926,20436.8%
Sep 21, 2026T2463,38210,1361,020,1342,77431.2%
Sep 14, 2026T2499,21410,904736,7632,30540.4%
Sep 7, 2026T21,156,65114,6122,461,3137,05032.0%
Aug 31, 2026T2655,33413,1671,550,8974,55129.7%
Aug 24, 2026T2443,7787,914936,9962,79132.1%
Aug 17, 2026T2551,0468,176968,5973,68536.3%
Aug 10, 2026T22,105,82319,5925,413,54513,75228.0%
Aug 3, 2026T2643,2849,4352,063,7005,22423.8%
Jul 27, 2026T2445,2446,6861,717,0244,36320.6%
Jul 20, 2026T2676,9269,7452,886,8027,71419.0%