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Personalis, Inc.

PSNL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001527753

In the last 90 days, Personalis, Inc. insiders filed 0 open-market purchases and 6 sales; 158 institutions reported holding it in 13F filings for Q2 2026, worth $1.14B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Personalis, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
+17 vs. Q3 2025
Shares held
81.0M
+16.3M (+25.2%) vs. Q3 2025
Total value
$644.8M
+$222.9M (+52.8%) vs. Q3 2025
New holders
31
37 more added
Sold out
14
38 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PSNL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 126 institutions
Q1 2021: 134 institutionsQ2 2021: 136 institutionsQ3 2021: 120 institutionsQ4 2021: 108 institutionsQ1 2022: 125 institutionsQ2 2022: 99 institutionsQ3 2022: 81 institutionsQ4 2022: 80 institutionsQ1 2023: 63 institutionsQ2 2023: 66 institutionsQ3 2023: 63 institutionsQ4 2023: 69 institutionsQ1 2024: 71 institutionsQ2 2024: 69 institutionsQ3 2024: 83 institutionsQ4 2024: 107 institutionsQ1 2025: 104 institutionsQ2 2025: 105 institutionsQ3 2025: 109 institutionsQ4 2025: 126 institutionsQ1 2026: 140 institutionsQ2 2026: 158 institutions
Value heldQ4 2025: $644.8M
Q1 2021: $763.1MQ2 2021: $807.9MQ3 2021: $604.2MQ4 2021: $456.2MQ1 2022: $265.3MQ2 2022: $105.6MQ3 2022: $83.9MQ4 2022: $55.0MQ1 2023: $75.0MQ2 2023: $49.0MQ3 2023: $30.0MQ4 2023: $46.1MQ1 2024: $33.2MQ2 2024: $25.7MQ3 2024: $157.6MQ4 2024: $298.2MQ1 2025: $192.4MQ2 2025: $396.6MQ3 2025: $421.8MQ4 2025: $644.8MQ1 2026: $538.8MQ2 2026: $1.14B
Institutions holding PSNL and their total value by quarter
QuarterHoldersValue
Q2 2026158$1.14B
Q1 2026140$538.8M
Q4 2025126$644.8M
Q3 2025109$421.8M
Q2 2025105$396.6M
Q1 2025104$192.4M
Q4 2024107$298.2M
Q3 202483$157.6M
Q2 202469$25.7M
Q1 202471$33.2M
Q4 202369$46.1M
Q3 202363$30.0M
Q2 202366$49.0M
Q1 202363$75.0M
Q4 202280$55.0M
Q3 202281$83.9M
Q2 202299$105.6M
Q1 2022125$265.3M
Q4 2021108$456.2M
Q3 2021120$604.2M
Q2 2021136$807.9M
Q1 2021134$763.1M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Personalis, Inc.; share changes are against Q3 2025.

Institutions holding PSNL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Merck & Co., Inc.14,044,943$111.8M40.47%00.0%Unchanged
T. Rowe Price Investment Management, Inc.10,780,290$85.8M0.05%+7,896,714+273.9%Added
Lightspeed Management Company, L.L.C.8,160,734$65.0M4.65%00.0%Unchanged
ARK Investment Management LLCSuperinvestorARK Invest7,879,087$62.7M0.42%−31,104−0.4%Reduced
Ameriprise Financial Inc6,287,151$50.0M0.01%+5,988,126+2,002.6%Added
BlackRock, Inc.5,319,508$42.3M0.00%−325,291−5.8%Reduced
Vanguard Group Inc3,253,797$25.9M0.00%+247,387+8.2%Added
Standard Life Aberdeen plc3,249,895$25.9M0.04%+861,948+36.1%Added
AIGH Capital Management LLC2,900,000$23.1M6.82%−992,101−25.5%Reduced
Kennedy Capital Management, Inc.1,712,652$13.6M0.29%−222,426−11.5%Reduced
Blue Water Life Science Advisors, LLC1,676,300$13.3M8.37%00.0%Unchanged
Price T Rowe Associates Inc1,448,585$11.5M0.00%+1,347,439+1,332.2%Added
Geode Capital Management, LLC1,297,807$10.3M0.00%−35,734−2.7%Reduced
State Street Corp1,050,590$8.36M0.00%+124,243+13.4%Added
Dimensional Fund Advisors LP983,174$7.83M0.00%+9,519+1.0%Added
PFM Health Sciences, LP805,817$6.41M0.65%+805,817New
Next Century Growth Investors LLC624,363$4.97M0.35%+624,363New
Howland Capital Management LLC547,115$4.36M0.17%+216,442+65.5%Added
Sumitomo Mitsui Trust Holdings, Inc.518,441$4.13M0.00%−72,555−12.3%Reduced
Nikko Asset Management Americas, Inc.518,441$4.13M0.05%−72,555−12.3%Reduced
State of Michigan Retirement System493,798$3.93M0.02%00.0%Unchanged
Portolan Capital Management, LLC379,197$3.02M0.16%+379,197New
First Manhattan Co373,822$2.98M0.01%+373,822New
Northern Trust Corp354,918$2.83M0.00%−38,866−9.9%Reduced
Goldman Sachs Group Inc342,475$2.73M0.00%−231,506−40.3%Reduced
Wellington Shields Capital Management, LLC340,000$2.71M0.39%+47,865+16.4%Added
Oracle Investment Management Inc339,343$2.70M1.77%+109,908+47.9%Added
Nuveen, LLC308,680$2.46M0.00%00.0%Unchanged
UBS Group AG306,568$2.44M0.00%+11,004+3.7%Added
Wellington Shields & Co., LLC292,489$2.33M0.57%00.0%Unchanged
Nano Cap New Millennium Growth Fund L P290,000$2.31M1.97%+290,000New
TD Asset Management Inc271,876$2.16M0.00%+217,292+398.1%Added
Davy Global Fund Management Ltd267,674$2.13M0.15%+82,638+44.7%Added
Perkins Capital Management Inc239,000$1.90M1.51%−13,500−5.3%Reduced
Bruce & Co., Inc.233,000$1.85M0.58%−20,000−7.9%Reduced
Morgan Stanley224,563$1.79M0.00%−117,492−34.3%Reduced
Jane Street Group, LLC171,166$1.36M0.00%+171,166New
Charles Schwab Investment Management Inc158,170$1.26M0.00%+280.0%Added
D.A. Davidson & Co.145,507$1.16M0.01%+145,507New
Williams Jones Wealth Management, LLC.134,072$1.07M0.01%00.0%Unchanged
LPL Financial LLC132,343$1.05M0.00%−1,749−1.3%Reduced
Bank of New York Mellon Corp122,951$978.7K0.00%−2,361−1.9%Reduced
Barclays PLC119,951$954.8K0.00%+5,148+4.5%Added
American Century Companies Inc114,001$907.4K0.00%+1,991+1.8%Added
Susquehanna Fundamental Investments, LLC108,951$867.3K0.03%00.0%Unchanged
HRT Financial LP97,772$778.0K0.00%+97,772New
Renaissance Technologies LLC92,994$740.2K0.00%−360,049−79.5%Reduced
Citadel Advisors LLC92,162$733.6K0.00%+92,162New
Royal Bank of Canada79,310$631.0K0.00%−75,067−48.6%Reduced
Green Alpha Advisors, LLC68,517$545.4K0.50%+40,126+141.3%Added
Wells Fargo & Company64,251$511.4K0.00%+17,322+36.9%Added
Rhumbline Advisers64,181$510.9K0.00%−9,934−13.4%Reduced
Susquehanna Portfolio Strategies, LLC61,844$492.3K0.01%00.0%Unchanged
Bank of America Corp60,033$477.9K0.00%+26,134+77.1%Added
Mirae Asset Global ETFs Holdings Ltd.56,834$452.4K0.00%−7,831−12.1%Reduced
SEI Investments Co56,006$445.8K0.00%+56,006New
Verition Fund Management LLC51,804$412.4K0.00%+51,804New
Polen Capital Management LLC50,705$403.6K0.00%+50,705New
AlphaCentric Advisors LLC47,796$380.5K0.38%+47,796New
SG Americas Securities, LLC44,678$356.0K0.00%+44,678New
Invesco Ltd.39,875$317.4K0.00%−338−0.8%Reduced
XTX Topco Ltd39,412$313.7K0.01%−43,297−52.3%Reduced
Pathstone Holdings, LLC39,015$310.6K0.00%+39,015New
Deutsche Bank AG38,827$309.1K0.00%+1,655+4.5%Added
Two Sigma Investments, LP32,476$258.5K0.00%−24,282−42.8%Reduced
Susquehanna International Group, LLP30,967$246.5K0.00%−12,581−28.9%Reduced
Janney Montgomery Scott LLC30,000$239.0K0.00%+5,000+20.0%Added
Alliancebernstein L.P.28,700$228.5K0.00%00.0%Unchanged
Citigroup Inc27,608$219.8K0.00%+25,318+1,105.6%Added
JPMorgan Chase & Co26,716$212.7K0.00%+1,883+7.6%Added
Intech Investment Management LLC20,342$161.9K0.00%+3,851+23.4%Added
US Bancorp20,062$159.7K0.00%+20,062New
MetLife Investment Management18,658$148.5K0.00%−11,135−37.4%Reduced
New York State Common Retirement Fund15,800$125.8K0.00%00.0%Unchanged
Creative Planning15,768$125.5K0.00%+3,210+25.6%Added
Manufacturers Life Insurance Company, The15,745$125.3K0.00%−1,705−9.8%Reduced
Axq Capital, LP14,965$119.1K0.03%+14,965New
China Universal Asset Management Co., Ltd.14,471$115.2K0.01%−1,073−6.9%Reduced
Stifel Financial Corp13,933$110.9K0.00%−34,068−71.0%Reduced
Guggenheim Capital LLC13,578$108.1K0.00%+13,578New
Colony Group, LLC13,527$107.7K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA13,456$107.1K0.00%−1,340−9.1%Reduced
ProShare Advisors LLC13,081$104.1K0.00%+1,348+11.5%Added
Police & Firemen's Retirement System of New Jersey12,974$103.3K0.00%00.0%Unchanged
Scientech Research LLC12,402$98.7K0.06%+12,402New
Skopos Labs, Inc.12,045$95.5K0.00%+12,045New
Raymond James Financial Inc11,600$92.3K0.00%00.0%Unchanged
Simplex Trading, LLC10,923$86.9K0.00%+4,847+79.8%Added
HSBC Holdings PLC10,474$84.1K0.00%−40,967−79.6%Reduced
DRW Securities, LLC10,483$83.4K0.01%+10,483New
AQR Capital Management LLC10,240$81.5K0.00%+10,240New
Advisor Group Holdings, Inc.6,495$51.7K0.00%+1,450+28.7%Added
Quest Partners LLC5,007$39.9K0.00%+5,007New
Legal & General Group Plc4,572$36.4K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.4,315$34.3K0.00%+887+25.9%Added
Ameritas Investment Partners, Inc.4,235$33.7K0.00%−885−17.3%Reduced
Russell Investments Group, Ltd.4,184$33.3K0.00%+31+0.7%Added
International Assets Investment Management, LLC3,900$31.0K0.00%+3,900New
Caitong International Asset Management Co., Ltd3,423$27.2K0.01%+1,479+76.1%Added
FMR LLC3,391$27.0K0.00%+1,037+44.1%Added