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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q1 2026

Institutional positions in Pacific Biosciences of California, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
231
+21 vs. Q4 2025
Shares held
188.2M
+4.50M (+2.5%) vs. Q4 2025
Total value
$248.5M
−$93.1M (−27.2%) vs. Q4 2025
New holders
52
60 more added
Sold out
31
71 more reduced

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 231 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ1 2026: $248.5M
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q4 2025.

Institutions holding PACB in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)918,892$1.21M0.07%00.0%Unchanged
Bourne Lent Asset Management Inc951,055$1.26M0.46%−16,000−1.7%Reduced
Goldman Sachs Group Inc988,467$1.30M0.00%−390,405−28.3%Reduced
Qube Research & Technologies Ltd1,184,975$1.56M0.00%+1,184,975New
HRT Financial LP1,265,535$1.67M0.00%−98,042−7.2%Reduced
Jane Street Group, LLC1,390,070$1.83M0.00%−110,448−7.4%Reduced
Invesco Ltd.1,468,148$1.94M0.00%+35,137+2.5%Added
Birchview Capital, LP1,500,000$1.98M1.13%+1,000,000+200.0%Added
Citadel Advisors LLC1,576,051$2.08M0.00%−1,590,190−50.2%Reduced
UBS Group AG1,640,099$2.16M0.00%−1,531,447−48.3%Reduced
Bank of America Corp1,666,706$2.20M0.00%−188,108−10.1%Reduced
Susquehanna International Group, LLP1,719,165$2.27M0.00%−892,378−34.2%Reduced
Davy Global Fund Management Ltd1,788,393$2.36M0.18%−106,538−5.6%Reduced
Morgan Stanley1,840,461$2.43M0.00%−570,079−23.6%Reduced
Vanguard Fiduciary Trust Co1,986,483$2.62M0.00%+1,986,483New
Northern Trust Corp2,130,788$2.81M0.00%+83,949+4.1%Added
Charles Schwab Investment Management Inc2,405,496$3.18M0.00%−60,357−2.4%Reduced
Renaissance Technologies LLC2,489,100$3.29M0.01%−1,361,500−35.4%Reduced
Vanguard Portfolio Management LLC2,868,393$3.79M0.00%+2,868,393New
Nuveen, LLC2,950,929$3.90M0.00%+2,102,710+247.9%Added
Two Sigma Investments, LP3,509,613$4.63M0.00%+632,429+22.0%Added
D. E. Shaw & Co., Inc.3,637,547$4.80M0.00%−800,726−18.0%Reduced
Millennium Management LLC4,892,318$6.46M0.00%+547,749+12.6%Added
State Street Corp6,121,716$8.08M0.00%+209,493+3.5%Added
Geode Capital Management, LLC6,975,266$9.21M0.00%−103,478−1.5%Reduced
Nikko Asset Management Americas, Inc.7,037,987$9.22M0.13%−770,593−9.9%Reduced
Sumitomo Mitsui Trust Holdings, Inc.7,037,987$9.29M0.01%−770,593−9.9%Reduced
Vanguard Capital Management LLC12,777,449$16.9M0.00%+12,777,449New
Softbank Group Corp20,451,570$27.0M0.24%00.0%Unchanged
BlackRock, Inc.25,267,429$33.4M0.00%+1,922,459+8.2%Added
ARK Investment Management LLCSuperinvestorARK Invest36,273,288$47.9M0.37%−990,940−2.7%Reduced
Koss-Olinger Consulting, LLC0$00.00%−2,600,000−100.0%Sold out
Amiral Gestion0$00.00%−2,733,290−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−827,500−100.0%Sold out
Headlands Technologies LLC0$00.00%−733,840−100.0%Sold out
Squarepoint Ops LLC0$00.00%−448,558−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−73,300−100.0%Sold out
Polen Capital Management LLC0$00.00%−137,149−100.0%Sold out
Bank of Montreal0$00.00%−126,923−100.0%Sold out
Mariner, LLC0$00.00%−40,004−100.0%Sold out
Western Wealth Management, LLC0$00.00%−35,345−100.0%Sold out
Magnetar Financial LLC0$00.00%−31,602−100.0%Sold out
Ambassador Advisors, LLC0$00.00%−30,000−100.0%Sold out
Atria Investments LLC0$00.00%−27,496−100.0%Sold out
Gallagher Fiduciary Advisors, LLC0$00.00%−23,486−100.0%Sold out
Outlook Wealth Advisors, LLC0$00.00%−18,000−100.0%Sold out
Pinnacle Wealth Planning Services, Inc.0$00.00%−17,849−100.0%Sold out
Pathstone Holdings, LLC0$00.00%−16,178−100.0%Sold out
Mackenzie Financial Corp0$00.00%−17,499−100.0%Sold out
Tactive Advisors, LLC0$00.00%−13,097−100.0%Sold out
Cim Investment Mangement Inc0$00.00%−12,301−100.0%Sold out
Verdence Capital Advisors LLC0$00.00%−10,415−100.0%Sold out
Amalgamated Bank0$00.00%−8,675−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−3,590−100.0%Sold out
BOK Financial Private Wealth, Inc.0$00.00%−2,500−100.0%Sold out
Novem Group0$00.00%−1,100−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−909−100.0%Sold out
Fortitude Family Office, LLC0$00.00%−793−100.0%Sold out
T. Rowe Price Investment Management, Inc.0$00.00%−217−100.0%Sold out
Colonial Trust Advisors0$00.00%−500−100.0%Sold out
United Financial Planning Group LLC0$00.00%−250−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−103−100.0%Sold out
Vanguard Group Inc––––Not filed
CIBC World Markets Corp––––Not filed
Comerica Bank––––Not filed
CIBC Private Wealth Group, LLC––––Not filed
Global Retirement Partners, LLC––––Not filed
DV Equities, LLC––––Not filed