Pacific Biosciences of California, Inc.
PACB- Exchange
- Nasdaq
- Industry
- Laboratory Analytical Instruments
- SEC CIK
- 0001299130
In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.
13F holders, Q4 2025
Institutional positions in Pacific Biosciences of California, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 216
- +12 vs. Q3 2025
- Shares held
- 200.7M
- +18.9M (+10.4%) vs. Q3 2025
- Total value
- $373.5M
- +$141.3M (+60.8%) vs. Q3 2025
- New holders
- 43
- 69 more added
- Sold out
- 31
- 50 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 223 | $320.8M |
| Q1 2026 | 231 | $248.5M |
| Q4 2025 | 216 | $373.5M |
| Q3 2025 | 208 | $237.8M |
| Q2 2025 | 207 | $245.8M |
| Q1 2025 | 225 | $265.6M |
| Q4 2024 | 227 | $475.1M |
| Q3 2024 | 226 | $394.3M |
| Q2 2024 | 229 | $331.9M |
| Q1 2024 | 268 | $1.01B |
| Q4 2023 | 274 | $2.76B |
| Q3 2023 | 275 | $2.20B |
| Q2 2023 | 272 | $3.37B |
| Q1 2023 | 260 | $2.93B |
| Q4 2022 | 237 | $1.84B |
| Q3 2022 | 227 | $1.23B |
| Q2 2022 | 230 | $1.03B |
| Q1 2022 | 250 | $2.03B |
| Q4 2021 | 256 | $4.20B |
| Q3 2021 | 246 | $4.83B |
| Q2 2021 | 261 | $6.04B |
| Q1 2021 | 263 | $5.47B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Two Sigma Investments, LP | 2,877,184 | $5.38M | 0.01% | +2,475,418+616.1% | Added |
| Point72 Asset Management, L.P. | 2,957,400 | $5.53M | 0.01% | +2,957,400 | New |
| Citadel Advisors LLC | 3,166,241 | $5.92M | 0.00% | +667,887+26.7% | Added |
| UBS Group AG | 3,171,546 | $5.93M | 0.00% | +1,674,320+111.8% | Added |
| Renaissance Technologies LLC | 3,850,600 | $7.20M | 0.01% | +3,850,600 | New |
| Casdin Capital, LLC | 4,223,767 | $7.90M | 0.49% | +3,500,000+483.6% | Added |
| Millennium Management LLC | 4,344,569 | $8.12M | 0.01% | −572,226−11.6% | Reduced |
| D. E. Shaw & Co., Inc. | 4,438,273 | $8.30M | 0.01% | +4,438,273 | New |
| State Street Corp | 5,912,223 | $11.1M | 0.00% | +2,5790.0% | Added |
| Geode Capital Management, LLC | 7,078,744 | $13.2M | 0.00% | +172,089+2.5% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 7,808,580 | $14.6M | 0.01% | −868,978−10.0% | Reduced |
| Nikko Asset Management Americas, Inc. | 7,808,580 | $14.6M | 0.17% | −868,978−10.0% | Reduced |
| Vanguard Group Inc | 17,037,314 | $31.9M | 0.00% | +657,342+4.0% | Added |
| Softbank Group Corp | 20,451,570 | $38.2M | 0.25% | 00.0% | Unchanged |
| BlackRock, Inc. | 23,344,970 | $43.7M | 0.00% | +649,218+2.9% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 37,264,228 | $69.7M | 0.46% | +6,340,125+20.5% | Added |
| Edmond de Rothschild Holding S.A. | 0 | $0 | 0.00% | −10,675,200−100.0% | Sold out |
| Madrone Advisors, LLC | 0 | $0 | 0.00% | −4,976,089−100.0% | Sold out |
| PEAK6 LLC | 0 | $0 | 0.00% | −890,598−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −250,276−100.0% | Sold out |
| Main Street Research LLC | 0 | $0 | 0.00% | −142,100−100.0% | Sold out |
| Marex Group plc | 0 | $0 | 0.00% | −118,200−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −101,957−100.0% | Sold out |
| NJ State Employees Deferred Compensation Plan | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −71,768−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −61,900−100.0% | Sold out |
| Archford Capital Strategies, LLC | 0 | $0 | 0.00% | −51,194−100.0% | Sold out |
| GTS Securities LLC | 0 | $0 | 0.00% | −45,306−100.0% | Sold out |
| Water Island Capital LLC | 0 | $0 | 0.00% | −35,754−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −25,000−100.0% | Sold out |
| Zacks Investment Management | 0 | $0 | 0.00% | −19,170−100.0% | Sold out |
| Beta Wealth Group, Inc. | 0 | $0 | 0.00% | −19,000−100.0% | Sold out |
| Gotham Asset Management, LLC | 0 | $0 | 0.00% | −18,763−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −17,161−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −14,223−100.0% | Sold out |
| Alpine Global Management, LLC | 0 | $0 | 0.00% | −13,848−100.0% | Sold out |
| Worth Asset Management, LLC | 0 | $0 | 0.00% | −13,100−100.0% | Sold out |
| Ethos Financial Group, LLC | 0 | $0 | 0.00% | −12,100−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −11,854−100.0% | Sold out |
| Equitable Holdings, Inc. | 0 | $0 | 0.00% | −11,500−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −11,154−100.0% | Sold out |
| Baader Bank INC | 0 | $0 | 0.00% | −12,081−100.0% | Sold out |
| Newbridge Financial Services Group, Inc. | 0 | $0 | 0.00% | −6,000−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −481−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −424−100.0% | Sold out |
| ORG Wealth Partners, LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| JPL Wealth Management, LLC | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |
| Wolverine Trading, LLC | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |
| Moloney Securities Asset Management, LLC | – | – | – | – | Not filed |