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OptimizeRx Corp

OPRX
Exchange
Nasdaq
Industry
Services-Business Services, NEC
SEC CIK
0001448431

No open-market purchases or sales by OptimizeRx Corp insiders were filed in the last 90 days; 112 institutions reported holding it in 13F filings for Q2 2026, worth $64.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in OptimizeRx Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
129
+4 vs. Q3 2025
Shares held
13.3M
−6.42K (0.0%) vs. Q3 2025
Total value
$163.9M
−$109.8M (−40.1%) vs. Q3 2025
New holders
26
39 more added
Sold out
22
39 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 129 institutions
Q1 2021: 121 institutionsQ2 2021: 142 institutionsQ3 2021: 163 institutionsQ4 2021: 180 institutionsQ1 2022: 153 institutionsQ2 2022: 147 institutionsQ3 2022: 128 institutionsQ4 2022: 129 institutionsQ1 2023: 110 institutionsQ2 2023: 102 institutionsQ3 2023: 95 institutionsQ4 2023: 98 institutionsQ1 2024: 97 institutionsQ2 2024: 92 institutionsQ3 2024: 85 institutionsQ4 2024: 87 institutionsQ1 2025: 87 institutionsQ2 2025: 111 institutionsQ3 2025: 125 institutionsQ4 2025: 129 institutionsQ1 2026: 128 institutionsQ2 2026: 112 institutions
Value heldQ4 2025: $163.9M
Q1 2021: $566.9MQ2 2021: $760.9MQ3 2021: $1.19BQ4 2021: $930.5MQ1 2022: $585.1MQ2 2022: $428.1MQ3 2022: $204.5MQ4 2022: $229.8MQ1 2023: $196.3MQ2 2023: $184.1MQ3 2023: $101.8MQ4 2023: $178.8MQ1 2024: $155.4MQ2 2024: $130.8MQ3 2024: $95.5MQ4 2024: $55.3MQ1 2025: $101.6MQ2 2025: $168.2MQ3 2025: $273.7MQ4 2025: $163.9MQ1 2026: $85.8MQ2 2026: $64.2M
Institutions holding OPRX and their total value by quarter
QuarterHoldersValue
Q2 2026112$64.2M
Q1 2026128$85.8M
Q4 2025129$163.9M
Q3 2025125$273.7M
Q2 2025111$168.2M
Q1 202587$101.6M
Q4 202487$55.3M
Q3 202485$95.5M
Q2 202492$130.8M
Q1 202497$155.4M
Q4 202398$178.8M
Q3 202395$101.8M
Q2 2023102$184.1M
Q1 2023110$196.3M
Q4 2022129$229.8M
Q3 2022128$204.5M
Q2 2022147$428.1M
Q1 2022153$585.1M
Q4 2021180$930.5M
Q3 2021163$1.19B
Q2 2021142$760.9M
Q1 2021121$566.9M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding OptimizeRx Corp; share changes are against Q3 2025.

Institutions holding OPRX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Pinnacle Wealth Planning Services, Inc.1$120.00%+1New
IFP Advisors, Inc2$250.00%+2New
Rothschild Investment LLC5$610.00%+5New
Farther Finance Advisors, LLC10$1230.00%00.0%Unchanged
Sunbelt Securities, Inc.11$1350.00%00.0%Unchanged
True Wealth Design, LLC14$1720.00%00.0%Unchanged
EverSource Wealth Advisors, LLC29$3550.00%−2−6.5%Reduced
The PNC Financial Services Group, Inc.62$7600.00%−197−76.1%Reduced
SRS Capital Advisors, Inc.90$1.10K0.00%−235−72.3%Reduced
Torren Management, LLC97$1.19K0.00%+97New
AdvisorNet Financial, Inc100$1.23K0.00%00.0%Unchanged
HighMark Wealth Management LLC100$1.23K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co100$1.23K0.00%+100New
Sterling Capital Management LLC103$1.26K0.00%+65+171.1%Added
Federated Hermes, Inc.112$1.37K0.00%−240−68.2%Reduced
Optiver Holding B.V.132$1.62K0.00%00.0%Unchanged
Leonteq Securities AG139$1.70K0.00%00.0%Unchanged
SBI Securities Co., Ltd.253$3.10K0.00%−20−7.3%Reduced
Citigroup Inc358$4.39K0.00%−624−63.5%Reduced
Compagnie Lombard Odier SCmA410$5.03K0.00%00.0%Unchanged
Amalgamated Bank496$6.00K0.00%−96−16.2%Reduced
GAMMA Investing LLC565$6.93K0.00%+9+1.6%Added
MCF Advisors LLC631$7.74K0.00%+361+133.7%Added
UBS Asset Management Americas Inc639$7.83K0.00%+639New
CWM, LLC683$8.00K0.00%−18−2.6%Reduced
Jones Financial Companies LLLP760$9.32K0.00%00.0%Unchanged
California State Teachers Retirement System972$11.9K0.00%−302−23.7%Reduced
Steward Partners Investment Advisory, LLC1,000$12.3K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,227$15.0K0.00%−1,445−54.1%Reduced
Ameritas Investment Partners, Inc.1,258$15.4K0.00%00.0%Unchanged
Bard Associates Inc1,480$18.1K0.00%+1,480New
Legal & General Group Plc1,580$19.4K0.00%−78−4.7%Reduced
Versant Capital Management, Inc1,793$22.0K0.00%00.0%Unchanged
Royal Bank of Canada1,851$23.0K0.00%−1,112−37.5%Reduced
Covestor Ltd1,914$23.0K0.01%00.0%Unchanged
Avalon Trust Co2,000$24.5K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC2,121$26.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,147$26.3K0.00%+1,156+116.6%Added
Simplex Trading, LLC4,091$50.2K0.00%+3,397+489.5%Added
BNP Paribas Arbitrage, SA4,257$52.2K0.00%+331+8.4%Added
Police & Firemen's Retirement System of New Jersey4,583$56.2K0.00%00.0%Unchanged
New York State Common Retirement Fund5,034$61.7K0.00%00.0%Unchanged
State of Alaska, Department of Revenue5,067$62.0K0.00%+5,067New
FMR LLC5,591$68.5K0.00%−277−4.7%Reduced
MAI Capital Management5,700$69.9K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.7,356$90.2K0.00%+126+1.7%Added
Group One Trading, L.P.8,051$98.7K0.00%−1,623−16.8%Reduced
JPMorgan Chase & Co8,173$100.2K0.00%+1,609+24.5%Added
Virtus ETF Advisers LLC9,687$118.8K0.06%−15,500−61.5%Reduced
MetLife Investment Management9,844$120.7K0.00%−1,535−13.5%Reduced
Quantbot Technologies LP9,847$120.7K0.00%+9,847New
State of Wyoming10,535$129.2K0.01%−11,298−51.7%Reduced
Worth Venture Partners, LLC10,750$131.8K0.95%00.0%Unchanged
Prelude Capital Management, LLC11,063$135.6K0.01%+11,063New
Point72 Asset Management, L.P.11,965$146.7K0.00%+11,965New
Citadel Advisors LLC11,976$146.8K0.00%−96,815−89.0%Reduced
ExodusPoint Capital Management, LP12,252$150.2K0.00%+12,252New
Deutsche Bank AG12,397$152.0K0.00%+733+6.3%Added
Gsa Capital Partners LLP12,604$155.0K0.01%+12,604New
Campbell & CO Investment Adviser LLC12,908$158.3K0.01%+12,908New
Canada Pension Plan Investment Board13,900$170.4K0.00%+13,900New
AQR Capital Management LLC14,514$177.9K0.00%+2,256+18.4%Added
Franklin Resources Inc16,284$199.6K0.00%−12,346−43.1%Reduced
Independent Financial Group, LLC16,500$202.3K0.00%+16,500New
HRT Financial LP17,295$212.0K0.00%+17,295New
Perkins Capital Management Inc17,408$213.4K0.17%−20,188−53.7%Reduced
Quantinno Capital Management LP17,504$214.6K0.00%+3,157+22.0%Added
Engineers Gate Manager LP18,634$228.5K0.00%+18,634New
Marshall Wace, LLP19,825$243.1K0.00%−15,582−44.0%Reduced
Hillsdale Investment Management Inc.20,300$248.9K0.01%+2,000+10.9%Added
GWN Securities Inc.22,358$274.1K0.06%+22,358New
STRS Ohio24,500$300.4K0.00%00.0%Unchanged
Harbor Capital Advisors, Inc.24,876$305.0K0.02%+2,708+12.2%Added
CenterBook Partners LP25,224$309.2K0.02%−283,585−91.8%Reduced
Ameriprise Financial Inc25,351$310.8K0.00%−44,055−63.5%Reduced
LPL Financial LLC26,698$327.3K0.00%−1,677−5.9%Reduced
Barclays PLC27,441$336.4K0.00%+4,317+18.7%Added
Rhumbline Advisers27,451$336.5K0.00%−4,963−15.3%Reduced
Principal Financial Group Inc27,531$337.5K0.00%+8,705+46.2%Added
Wells Fargo & Company28,903$354.4K0.00%+7,576+35.5%Added
Renaissance Technologies LLC29,578$362.6K0.00%−78,322−72.6%Reduced
Susquehanna International Group, LLP29,741$364.6K0.00%+29,741New
Prudential Financial Inc31,495$386.1K0.00%−54,990−63.6%Reduced
Diametric Capital, LP33,263$407.8K0.11%+33,263New
UBS Group AG34,960$428.6K0.00%+874+2.6%Added
Nuveen, LLC38,786$475.5K0.00%−5,337−12.1%Reduced
Alliancebernstein L.P.39,850$488.6K0.00%00.0%Unchanged
Bank of America Corp42,576$522.0K0.00%−42,184−49.8%Reduced
Millennium Management LLC43,669$535.4K0.00%+43,669New
Two Sigma Investments, LP46,181$566.2K0.00%−17,523−27.5%Reduced
State of Wisconsin Investment Board53,094$650.9K0.00%+25,533+92.6%Added
SEI Investments Co53,789$659.5K0.00%+53,789New
P.A.W. Capital Corp55,000$674.3K1.53%+5,000+10.0%Added
Qube Research & Technologies Ltd59,161$725.3K0.00%+40,578+218.4%Added
Bridgeway Capital Management, LLC69,029$846.3K0.02%+10,000+16.9%Added
Los Angeles Capital Management LLC44,577$874.2K0.00%−3,913−8.1%Reduced
Boothbay Fund Management, LLC73,488$901.0K0.02%+25,502+53.1%Added
Avenir Corp77,260$947.2K0.10%00.0%Unchanged
Charles Schwab Investment Management Inc81,318$997.0K0.00%+6,191+8.2%Added
Raymond James Financial Inc82,414$1.01M0.00%−2,358−2.8%Reduced