Omeros Corp
OMER- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001285819
In the last 90 days, Omeros Corp insiders filed 0 open-market purchases and 6 sales; 171 institutions reported holding it in 13F filings for Q2 2026, worth $343.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Omeros Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- +20 vs. Q3 2025
- Shares held
- 33.2M
- +422.9K (+1.3%) vs. Q3 2025
- Total value
- $570.3M
- +$435.7M (+323.9%) vs. Q3 2025
- New holders
- 33
- 61 more added
- Sold out
- 13
- 35 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OMER on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 171 | $343.0M |
| Q1 2026 | 162 | $326.2M |
| Q4 2025 | 151 | $570.3M |
| Q3 2025 | 133 | $134.7M |
| Q2 2025 | 128 | $87.3M |
| Q1 2025 | 137 | $226.7M |
| Q4 2024 | 128 | $262.3M |
| Q3 2024 | 108 | $99.3M |
| Q2 2024 | 104 | $101.4M |
| Q1 2024 | 99 | $87.8M |
| Q4 2023 | 97 | $81.7M |
| Q3 2023 | 100 | $78.9M |
| Q2 2023 | 103 | $142.8M |
| Q1 2023 | 91 | $94.9M |
| Q4 2022 | 98 | $44.4M |
| Q3 2022 | 94 | $64.7M |
| Q2 2022 | 102 | $66.0M |
| Q1 2022 | 129 | $173.2M |
| Q4 2021 | 139 | $202.2M |
| Q3 2021 | 142 | $417.7M |
| Q2 2021 | 152 | $478.4M |
| Q1 2021 | 152 | $618.6M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Omeros Corp; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Brevan Howard Capital Management LP | 64,957 | $1.12M | 0.02% | −64,436−49.8% | Reduced |
| Polar Asset Management Partners Inc. | 68,800 | $1.18M | 0.02% | −1,429,786−95.4% | Reduced |
| Walleye Trading LLC | 69,653 | $1.20M | 0.02% | +55,980+409.4% | Added |
| Alliancebernstein L.P. | 73,490 | $1.26M | 0.00% | +5,900+8.7% | Added |
| Two Sigma Advisers, LP | 76,100 | $1.31M | 0.00% | −502,100−86.8% | Reduced |
| MML Investors Services, LLC | 77,875 | $1.34M | 0.00% | +18,700+31.6% | Added |
| Cambridge Investment Research Advisors, Inc. | 81,643 | $1.40M | 0.00% | +63,424+348.1% | Added |
| Quest Partners LLC | 82,597 | $1.42M | 0.08% | +82,596+8,259,600.0% | Added |
| Susquehanna Portfolio Strategies, LLC | 92,759 | $1.59M | 0.02% | −78,329−45.8% | Reduced |
| Price T Rowe Associates Inc | 95,745 | $1.64M | 0.00% | +6,217+6.9% | Added |
| Dimensional Fund Advisors LP | 96,948 | $1.67M | 0.00% | +96,948 | New |
| Rhumbline Advisers | 100,105 | $1.72M | 0.00% | −5,768−5.4% | Reduced |
| HighTower Advisors, LLC | 104,059 | $1.79M | 0.00% | +8,875+9.3% | Added |
| Walleye Capital LLC | 109,956 | $1.89M | 0.01% | +95,033+636.8% | Added |
| Bank of America Corp | 114,808 | $1.97M | 0.00% | −160,610−58.3% | Reduced |
| Ameriprise Financial Inc | 117,004 | $2.01M | 0.00% | +468+0.4% | Added |
| Barclays PLC | 120,490 | $2.07M | 0.00% | −11,458−8.7% | Reduced |
| Simplex Trading, LLC | 123,979 | $2.13M | 0.06% | +101,759+458.0% | Added |
| Group One Trading, L.P. | 133,269 | $2.29M | 0.07% | +34,972+35.6% | Added |
| Clutterbuck Capital Management LLC | 150,000 | $2.58M | 2.20% | +150,000 | New |
| Nuveen, LLC | 153,187 | $2.63M | 0.00% | +65,569+74.8% | Added |
| Invesco Ltd. | 154,782 | $2.66M | 0.00% | +32,707+26.8% | Added |
| Wells Fargo & Company | 165,280 | $2.84M | 0.00% | +31,176+23.2% | Added |
| Bank of New York Mellon Corp | 165,782 | $2.85M | 0.00% | +3,437+2.1% | Added |
| Itau Unibanco Holding S.A. | 180,000 | $3.05M | 0.08% | +180,000 | New |
| Wellington Management Group LLP | 202,617 | $3.48M | 0.00% | +8,170+4.2% | Added |
| EAM Investors, LLC | 207,480 | $3.56M | 0.40% | +207,480 | New |
| Goldman Sachs Group Inc | 227,294 | $3.90M | 0.00% | −108,793−32.4% | Reduced |
| Jump Financial, LLC | 228,000 | $3.92M | 0.05% | +228,000 | New |
| Citadel Advisors LLC | 240,352 | $4.13M | 0.00% | −152,876−38.9% | Reduced |
| Badgley Phelps Wealth Managers, LLC | 263,556 | $4.53M | 0.08% | 00.0% | Unchanged |
| Morgan Stanley | 386,152 | $6.63M | 0.00% | −1,603,582−80.6% | Reduced |
| Millennium Management LLC | 441,811 | $7.59M | 0.01% | +39,997+10.0% | Added |
| Jane Street Group, LLC | 463,622 | $7.96M | 0.01% | +182,535+64.9% | Added |
| Royal Bank of Canada | 498,399 | $8.56M | 0.00% | −45,277−8.3% | Reduced |
| Two Sigma Investments, LP | 524,757 | $9.01M | 0.01% | −408,557−43.8% | Reduced |
| Northern Trust Corp | 526,732 | $9.05M | 0.00% | −8,963−1.7% | Reduced |
| Charles Schwab Investment Management Inc | 593,222 | $10.2M | 0.00% | +39,755+7.2% | Added |
| Bank of Montreal | 601,643 | $10.3M | 0.00% | +38,548+6.8% | Added |
| Nomura Holdings Inc | 655,021 | $11.2M | 0.03% | +611,340+1,399.6% | Added |
| CI Private Wealth, LLC | 688,025 | $11.8M | 0.02% | +79,263+13.0% | Added |
| Susquehanna International Group, LLP | 741,895 | $12.7M | 0.02% | +631,316+570.9% | Added |
| D. E. Shaw & Co., Inc. | 754,999 | $13.0M | 0.01% | −250,236−24.9% | Reduced |
| Kotler Kevin | 905,635 | $15.6M | 11.49% | +905,635 | New |
| State Street Corp | 1,573,526 | $27.0M | 0.00% | +333,798+26.9% | Added |
| Geode Capital Management, LLC | 1,631,350 | $28.0M | 0.00% | +95,979+6.3% | Added |
| Stifel Financial Corp | 1,809,766 | $31.1M | 0.03% | −2,509−0.1% | Reduced |
| UBS Group AG | 2,222,982 | $38.2M | 0.01% | +1,513,893+213.5% | Added |
| Ingalls & Snyder LLC | 3,448,699 | $59.2M | 2.18% | −657,899−16.0% | Reduced |
| Vanguard Group Inc | 4,013,315 | $68.9M | 0.00% | +666,357+19.9% | Added |
| BlackRock, Inc. | 5,062,438 | $86.9M | 0.00% | +610,282+13.7% | Added |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −464,178−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −344,500−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −155,496−100.0% | Sold out |
| DeepCurrents Investment Group LLC | 0 | $0 | 0.00% | −120,918−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −53,266−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −49,197−100.0% | Sold out |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −33,678−100.0% | Sold out |
| Brighton Jones LLC | 0 | $0 | 0.00% | −31,539−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −21,533−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −10,004−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −1,369−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −50−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −26−100.0% | Sold out |
| Wolverine Trading, LLC | – | – | – | – | Not filed |
| SPC Financial, Inc. | – | – | – | – | Not filed |