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NextCure, Inc.

NXTC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001661059

In the last 90 days, NextCure, Inc. insiders filed 2 open-market purchases and 1 sale; 30 institutions reported holding it in 13F filings for Q2 2026, worth $2.78M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in NextCure, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
24
+7 vs. Q3 2025
Shares held
1.90M
+1.04M (+121.1%) vs. Q3 2025
Total value
$26.9M
+$21.9M (+435.7%) vs. Q3 2025
New holders
9
5 more added
Sold out
2
3 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting NXTC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 24 institutions
Q1 2021: 92 institutionsQ2 2021: 78 institutionsQ3 2021: 71 institutionsQ4 2021: 71 institutionsQ1 2022: 59 institutionsQ2 2022: 51 institutionsQ3 2022: 52 institutionsQ4 2022: 45 institutionsQ1 2023: 44 institutionsQ2 2023: 43 institutionsQ3 2023: 41 institutionsQ4 2023: 43 institutionsQ1 2024: 47 institutionsQ2 2024: 49 institutionsQ3 2024: 44 institutionsQ4 2024: 46 institutionsQ1 2025: 38 institutionsQ2 2025: 30 institutionsQ3 2025: 17 institutionsQ4 2025: 24 institutionsQ1 2026: 26 institutionsQ2 2026: 30 institutions
Value heldQ4 2025: $26.9M
Q1 2021: $179.8MQ2 2021: $124.2MQ3 2021: $99.5MQ4 2021: $86.2MQ1 2022: $64.3MQ2 2022: $67.9MQ3 2022: $41.8MQ4 2022: $18.9MQ1 2023: $19.6MQ2 2023: $24.0MQ3 2023: $16.6MQ4 2023: $15.3MQ1 2024: $36.0MQ2 2024: $25.5MQ3 2024: $21.7MQ4 2024: $13.1MQ1 2025: $7.38MQ2 2025: $5.65MQ3 2025: $5.03MQ4 2025: $26.9MQ1 2026: $23.0MQ2 2026: $2.78M
Institutions holding NXTC and their total value by quarter
QuarterHoldersValue
Q2 202630$2.78M
Q1 202626$23.0M
Q4 202524$26.9M
Q3 202517$5.03M
Q2 202530$5.65M
Q1 202538$7.38M
Q4 202446$13.1M
Q3 202444$21.7M
Q2 202449$25.5M
Q1 202447$36.0M
Q4 202343$15.3M
Q3 202341$16.6M
Q2 202343$24.0M
Q1 202344$19.6M
Q4 202245$18.9M
Q3 202252$41.8M
Q2 202251$67.9M
Q1 202259$64.3M
Q4 202171$86.2M
Q3 202171$99.5M
Q2 202178$124.2M
Q1 202192$179.8M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding NextCure, Inc.; share changes are against Q3 2025.

Institutions holding NXTC in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Affinity Asset Advisors, LLC247,294$3.51M0.25%+55,412+28.9%Added
Ikarian Capital, LLC238,303$3.38M0.44%+238,303New
Squadron Capital Management LLC236,966$3.36M1.50%+236,966New
Sofinnova Investments, Inc.222,654$3.16M0.14%00.0%Unchanged
Silverarc Capital Management, LLC176,057$2.50M0.36%+176,057New
Exome Asset Management LLC165,000$2.34M1.16%+165,000New
Pfizer Inc157,646$2.24M0.95%00.0%Unchanged
AWM Investment Company, Inc.117,371$1.67M0.16%+117,371New
Vanguard Group Inc91,910$1.30M0.00%+23,927+35.2%Added
Boothbay Fund Management, LLC69,617$987.9K0.03%+69,617New
Renaissance Technologies LLC33,634$477.3K0.00%+5,300+18.7%Added
BlackRock, Inc.27,793$394.4K0.00%−3,293−10.6%Reduced
Acadian Asset Management LLC26,765$379.0K0.00%−9,910−27.0%Reduced
Geode Capital Management, LLC23,157$328.7K0.00%+3,636+18.6%Added
Cardiff Park Advisors, LLC21,833$309.8K0.03%00.0%Unchanged
Millennium Management LLC13,033$184.9K0.00%+13,033New
Marshall Wace, LLP11,292$160.2K0.00%+11,292New
Sio Capital Management, LLC10,940$155.2K0.03%00.0%Unchanged
Barclays PLC5,626$79.8K0.00%00.0%Unchanged
UBS Group AG338$4.80K0.00%−263−43.8%Reduced
Bank of America Corp173$2.45K0.00%+150+652.2%Added
Morgan Stanley66$9370.00%+66New
JPMorgan Chase & Co61$8660.00%00.0%Unchanged
BNP Paribas Arbitrage, SA32$4540.00%00.0%Unchanged
Cable Car Capital LLC0$00.00%−63,178−100.0%Sold out
Citigroup Inc0$00.00%−1−100.0%Sold out