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Nautilus Biotechnology, Inc.

NAUT
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001808805

No open-market purchases or sales by Nautilus Biotechnology, Inc. insiders were filed in the last 90 days; 93 institutions reported holding it in 13F filings for Q2 2026, worth $93.7M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Nautilus Biotechnology, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
81
+16 vs. Q4 2025
Shares held
54.3M
+5.87M (+12.1%) vs. Q4 2025
Total value
$210.8M
+$116.3M (+123.1%) vs. Q4 2025
New holders
25
16 more added
Sold out
9
15 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting NAUT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 81 institutions
Q1 2021: 0 institutionsQ2 2021: 56 institutionsQ3 2021: 72 institutionsQ4 2021: 81 institutionsQ1 2022: 82 institutionsQ2 2022: 83 institutionsQ3 2022: 86 institutionsQ4 2022: 81 institutionsQ1 2023: 73 institutionsQ2 2023: 75 institutionsQ3 2023: 75 institutionsQ4 2023: 76 institutionsQ1 2024: 73 institutionsQ2 2024: 77 institutionsQ3 2024: 83 institutionsQ4 2024: 88 institutionsQ1 2025: 88 institutionsQ2 2025: 71 institutionsQ3 2025: 68 institutionsQ4 2025: 68 institutionsQ1 2026: 81 institutionsQ2 2026: 93 institutions
Value heldQ1 2026: $210.8M
Q1 2021: $0Q2 2021: $379.7MQ3 2021: $245.1MQ4 2021: $234.8MQ1 2022: $243.5MQ2 2022: $154.7MQ3 2022: $119.7MQ4 2022: $82.9MQ1 2023: $123.3MQ2 2023: $173.4MQ3 2023: $142.5MQ4 2023: $189.6MQ1 2024: $185.9MQ2 2024: $149.8MQ3 2024: $182.9MQ4 2024: $107.3MQ1 2025: $54.0MQ2 2025: $43.3MQ3 2025: $48.9MQ4 2025: $113.7MQ1 2026: $210.8MQ2 2026: $93.7M
Institutions holding NAUT and their total value by quarter
QuarterHoldersValue
Q2 202693$93.7M
Q1 202681$210.8M
Q4 202568$113.7M
Q3 202568$48.9M
Q2 202571$43.3M
Q1 202588$54.0M
Q4 202488$107.3M
Q3 202483$182.9M
Q2 202477$149.8M
Q1 202473$185.9M
Q4 202376$189.6M
Q3 202375$142.5M
Q2 202375$173.4M
Q1 202373$123.3M
Q4 202281$82.9M
Q3 202286$119.7M
Q2 202283$154.7M
Q1 202282$243.5M
Q4 202181$234.8M
Q3 202172$245.1M
Q2 202156$379.7M
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Nautilus Biotechnology, Inc.; share changes are against Q4 2025.

Institutions holding NAUT in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada91$00.00%−3,183−97.2%Reduced
Covestor Ltd8$00.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd1$40.00%+1New
EverSource Wealth Advisors, LLC18$700.00%−31−63.3%Reduced
CWM, LLC29$1130.00%−26−47.3%Reduced
Optiver Holding B.V.40$1550.00%00.0%Unchanged
SBI Securities Co., Ltd.100$3880.00%+100New
Your Advocates Ltd., LLP150$5820.00%00.0%Unchanged
Gill Capital Partners, LLC250$9700.00%+250New
Wells Fargo & Company260$1.01K0.00%−300−53.6%Reduced
Advisor Group Holdings, Inc.295$1.14K0.00%−420−58.7%Reduced
National Bank of Canada300$1.16K0.00%+300New
TD Waterhouse Canada Inc.1,000$3.35K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec1,000$3.88K0.00%+1,000New
FMR LLC3,343$13.0K0.00%−143−4.1%Reduced
Rockefeller Capital Management L.P.6,200$24.1K0.00%+1,200+24.0%Added
BFSG, LLC6,700$26.0K0.00%+6,700New
Nine Masts Capital Ltd10,395$40.3K0.01%+10,395New
Garde Capital, Inc.11,000$42.7K0.00%−7,000−38.9%Reduced
Schonfeld Strategic Advisors LLC12,010$46.6K0.00%+12,010New
CTC Alternative Strategies, Ltd.12,397$48.1K0.11%+12,397New
Vanguard Capital Wealth Advisors13,000$50.4K0.05%00.0%Unchanged
BNP Paribas Arbitrage, SA13,372$51.9K0.00%−14,339−51.7%Reduced
Engineers Gate Manager LP13,878$53.8K0.00%+13,878New
FNY Investment Advisers, LLC14,000$54.0K0.02%00.0%Unchanged
Blair William & Co15,000$58.2K0.00%+15,000New
Vanguard Global Advisers, LLC16,607$64.4K0.00%+16,607New
Public Employees Retirement System of Ohio19,300$74.9K0.00%+19,300New
Citigroup Inc21,142$82.0K0.00%−40,570−65.7%Reduced
Diametric Capital, LP22,806$88.5K0.02%+22,806New
Omers Administration Corp24,500$95.1K0.00%−80,285−76.6%Reduced
Callan Family Office, LLC25,970$100.8K0.00%00.0%Unchanged
UBS Group AG26,903$104.4K0.00%+21,740+421.1%Added
Hudson Bay Capital Management LP29,594$114.8K0.00%+10,532+55.3%Added
Badgley Phelps Wealth Managers, LLC30,000$116.4K0.00%00.0%Unchanged
Captrust Financial Advisors34,003$131.9K0.00%−80.0%Reduced
Presidio Capital Management, LLC34,664$134.5K0.04%00.0%Unchanged
SEI Investments Co38,643$149.9K0.00%+38,643New
Polen Capital Management LLC40,345$156.5K0.00%+40,345New
CAPROCK Group, Inc.44,090$171.1K0.00%00.0%Unchanged
Fayez Sarofim & Co45,000$174.6K0.00%00.0%Unchanged
Ashton Thomas Private Wealth, LLC45,000$174.6K0.00%00.0%Unchanged
Catalyst Funds Management Pty Ltd46,328$179.8K0.03%+46,328New
Jacobs Levy Equity Management, Inc46,394$180.0K0.00%+46,394New
HSBC Holdings PLC49,449$189.9K0.00%00.0%Unchanged
Morgan Stanley49,503$192.1K0.00%+10,919+28.3%Added
Citizens Financial Group Inc50,000$194.0K0.00%+50,000New
Gsa Capital Partners LLP54,699$212.0K0.01%−69,352−55.9%Reduced
Brevan Howard Capital Management LP60,501$234.7K0.00%+60,501New
Jane Street Group, LLC61,802$239.8K0.00%−145,035−70.1%Reduced
Bank of America Corp63,147$245.0K0.00%+42,980+213.1%Added
HRT Financial LP65,254$253.0K0.00%+65,254New
Palumbo Wealth Management LLC65,231$253.1K0.06%+24,098+58.6%Added
Barclays PLC73,325$284.5K0.00%+25,071+52.0%Added
Qube Research & Technologies Ltd79,623$308.9K0.00%−43,498−35.3%Reduced
Point72 Asset Management, L.P.83,043$322.2K0.00%+22,210+36.5%Added
Crown Advisors Management, Inc.100,000$388.0K0.26%+100,000New
Northern Trust Corp107,011$415.2K0.00%00.0%Unchanged
CI Private Wealth, LLC114,788$445.4K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC130,000$504.4K0.01%00.0%Unchanged
Crewe Advisors LLC136,052$527.9K0.05%00.0%Unchanged
BlackRock, Inc.187,671$728.2K0.00%−1,760−0.9%Reduced
Hillman Co200,000$776.0K0.30%00.0%Unchanged
State Street Corp216,270$839.1K0.00%+15,015+7.5%Added
Renaissance Technologies LLC265,700$1.03M0.00%+5,800+2.2%Added
Vanguard Fiduciary Trust Co305,526$1.19M0.00%+305,526New
Marshall Wace, LLP319,882$1.24M0.00%+202,823+173.3%Added
Dimensional Fund Advisors LP329,123$1.27M0.00%+43,684+15.3%Added
Goldman Sachs Group Inc390,768$1.52M0.00%+93,331+31.4%Added
Geode Capital Management, LLC603,524$2.34M0.00%+42,615+7.6%Added
Tikvah Management LLC726,895$2.82M0.87%00.0%Unchanged
Acadian Asset Management LLC741,246$2.87M0.00%+129,262+21.1%Added
Sentinel Trust Co Lba750,000$2.91M0.29%00.0%Unchanged
Millennium Management LLC1,273,383$4.94M0.00%+253,387+24.8%Added
Amazon.com, Inc.1,457,055$5.65M0.21%00.0%Unchanged
Comprehensive Financial Management LLC2,207,619$8.57M0.28%00.0%Unchanged
Clearstead Advisors, LLC2,329,784$9.04M0.08%+2,329,784New
Vanguard Capital Management LLC2,545,597$9.88M0.00%+2,545,597New
Cercano Management LLC7,172,985$27.8M1.20%00.0%Unchanged
Perceptive Advisors LLC12,594,211$48.9M0.97%00.0%Unchanged
AH Capital Management, L.L.C.17,653,917$68.5M5.31%00.0%Unchanged
Alyeska Investment Group, L.P.0$00.00%−253,468−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−42,916−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−40,200−100.0%Sold out
XTX Topco Ltd0$00.00%−33,608−100.0%Sold out
Virtu Financial LLC0$00.00%−23,532−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−16,239−100.0%Sold out
Squarepoint Ops LLC0$00.00%−11,316−100.0%Sold out
Group One Trading, L.P.0$00.00%−3,880−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−5−100.0%Sold out
Madrona Venture Group, LLC––––Not filed
Vanguard Group Inc––––Not filed
Clarius Group, LLC––––Not filed