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Nautilus Biotechnology, Inc.

NAUT
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001808805

No open-market purchases or sales by Nautilus Biotechnology, Inc. insiders were filed in the last 90 days; 93 institutions reported holding it in 13F filings for Q2 2026, worth $93.7M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Nautilus Biotechnology, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
68
−3 vs. Q2 2025
Shares held
57.9M
−1.86M (−3.1%) vs. Q2 2025
Total value
$48.9M
+$5.60M (+12.9%) vs. Q2 2025
New holders
9
8 more added
Sold out
12
29 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting NAUT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 68 institutions
Q1 2021: 0 institutionsQ2 2021: 56 institutionsQ3 2021: 72 institutionsQ4 2021: 81 institutionsQ1 2022: 82 institutionsQ2 2022: 83 institutionsQ3 2022: 86 institutionsQ4 2022: 81 institutionsQ1 2023: 73 institutionsQ2 2023: 75 institutionsQ3 2023: 75 institutionsQ4 2023: 76 institutionsQ1 2024: 73 institutionsQ2 2024: 77 institutionsQ3 2024: 83 institutionsQ4 2024: 88 institutionsQ1 2025: 88 institutionsQ2 2025: 71 institutionsQ3 2025: 68 institutionsQ4 2025: 68 institutionsQ1 2026: 81 institutionsQ2 2026: 93 institutions
Value heldQ3 2025: $48.9M
Q1 2021: $0Q2 2021: $379.7MQ3 2021: $245.1MQ4 2021: $234.8MQ1 2022: $243.5MQ2 2022: $154.7MQ3 2022: $119.7MQ4 2022: $82.9MQ1 2023: $123.3MQ2 2023: $173.4MQ3 2023: $142.5MQ4 2023: $189.6MQ1 2024: $185.9MQ2 2024: $149.8MQ3 2024: $182.9MQ4 2024: $107.3MQ1 2025: $54.0MQ2 2025: $43.3MQ3 2025: $48.9MQ4 2025: $113.7MQ1 2026: $210.8MQ2 2026: $93.7M
Institutions holding NAUT and their total value by quarter
QuarterHoldersValue
Q2 202693$93.7M
Q1 202681$210.8M
Q4 202568$113.7M
Q3 202568$48.9M
Q2 202571$43.3M
Q1 202588$54.0M
Q4 202488$107.3M
Q3 202483$182.9M
Q2 202477$149.8M
Q1 202473$185.9M
Q4 202376$189.6M
Q3 202375$142.5M
Q2 202375$173.4M
Q1 202373$123.3M
Q4 202281$82.9M
Q3 202286$119.7M
Q2 202283$154.7M
Q1 202282$243.5M
Q4 202181$234.8M
Q3 202172$245.1M
Q2 202156$379.7M
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Nautilus Biotechnology, Inc.; share changes are against Q2 2025.

Institutions holding NAUT in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CWM, LLC182$00.00%−2,818−93.9%Reduced
Covestor Ltd8$00.00%00.0%Unchanged
Cloud Capital Management, LLC49$00.00%+49New
Cubist Systematic Strategies, LLC1$10.00%−62,346−100.0%Reduced
True Wealth Design, LLC17$150.00%−130−88.4%Reduced
Optiver Holding B.V.40$340.00%+40New
SRS Capital Advisors, Inc.148$1250.00%+148New
Your Advocates Ltd., LLP150$1260.00%00.0%Unchanged
EverSource Wealth Advisors, LLC229$1930.00%−149−39.4%Reduced
Aventura Private Wealth, LLC350$2960.00%00.0%Unchanged
Guerra Advisors Inc400$3380.00%+400New
UBS Group AG470$3970.00%−15,850−97.1%Reduced
Wells Fargo & Company560$4730.00%−883−61.2%Reduced
Advisor Group Holdings, Inc.715$5850.00%00.0%Unchanged
Point72 (DIFC) Ltd789$6670.00%00.0%Unchanged
Bank of America Corp813$6860.00%−7,550−90.3%Reduced
Citigroup Inc884$7470.00%−3,729−80.8%Reduced
TD Waterhouse Canada Inc.1,000$8300.00%00.0%Unchanged
Royal Bank of Canada1,822$1.00K0.00%−482−20.9%Reduced
BNP Paribas Arbitrage, SA1,465$1.24K0.00%−1,963−57.3%Reduced
JPMorgan Chase & Co2,121$1.79K0.00%−206−8.9%Reduced
Rockefeller Capital Management L.P.5,000$4.22K0.00%+5,000New
Tower Research Capital LLC (TRC)5,603$4.73K0.00%−15,978−74.0%Reduced
FMR LLC8,660$7.32K0.00%−15,838−64.7%Reduced
FNY Investment Advisers, LLC14,000$11.0K0.00%00.0%Unchanged
Vanguard Capital Wealth Advisors13,500$11.4K0.01%−2,500−15.6%Reduced
CAPROCK Group, Inc.17,090$11.6K0.00%+17,090New
Callan Family Office, LLC14,830$12.5K0.00%−34,064−69.7%Reduced
Point72 Asia (Singapore) Pte. Ltd.16,271$13.7K0.00%−16,306−50.1%Reduced
Virtu Financial LLC19,683$17.0K0.00%+19,683New
Morgan Stanley25,728$21.7K0.00%−28,849−52.9%Reduced
Badgley Phelps Wealth Managers, LLC30,000$25.3K0.00%00.0%Unchanged
Presidio Capital Management, LLC34,664$29.3K0.01%00.0%Unchanged
Palumbo Wealth Management LLC42,117$35.6K0.01%+456+1.1%Added
Fayez Sarofim & Co45,000$38.0K0.00%00.0%Unchanged
Ashton Thomas Private Wealth, LLC45,000$38.0K0.00%+45,000New
XTX Topco Ltd45,724$38.6K0.00%−20,470−30.9%Reduced
HSBC Holdings PLC49,598$40.1K0.00%00.0%Unchanged
Barclays PLC48,254$40.8K0.00%−9,835−16.9%Reduced
Qube Research & Technologies Ltd51,667$43.7K0.00%−10,471−16.9%Reduced
Goldman Sachs Group Inc117,716$99.5K0.00%−197,222−62.6%Reduced
Northern Trust Corp117,836$99.6K0.00%−30,631−20.6%Reduced
Bridgeway Capital Management, LLC125,000$105.6K0.00%00.0%Unchanged
Squarepoint Ops LLC131,827$111.4K0.00%+30,005+29.5%Added
Crewe Advisors LLC136,052$115.0K0.01%+136,052New
Jane Street Group, LLC148,188$125.2K0.00%−142,181−49.0%Reduced
State Street Corp178,755$151.0K0.00%−2,861−1.6%Reduced
Hillman Co200,000$169.0K0.05%00.0%Unchanged
BlackRock, Inc.201,444$170.2K0.00%−427,457−68.0%Reduced
Acadian Asset Management LLC243,273$203.0K0.00%+174,065+251.5%Added
Alyeska Investment Group, L.P.253,468$214.2K0.00%00.0%Unchanged
Citadel Advisors LLC254,161$214.7K0.00%+76,006+42.7%Added
Gsa Capital Partners LLP259,203$219.0K0.02%+82,295+46.5%Added
Jacobs Levy Equity Management, Inc301,012$254.3K0.00%+46,153+18.1%Added
CI Private Wealth, LLC319,140$269.6K0.00%−116,210−26.7%Reduced
Dimensional Fund Advisors LP364,675$307.8K0.00%−186,065−33.8%Reduced
Geode Capital Management, LLC553,602$467.9K0.00%00.0%Unchanged
Tikvah Management LLC726,895$614.2K0.18%00.0%Unchanged
Millennium Management LLC967,548$817.5K0.00%−89,291−8.4%Reduced
Renaissance Technologies LLC1,007,662$851.4K0.00%+387,756+62.6%Added
Clarius Group, LLC1,209,646$1.02M0.06%+149,186+14.1%Added
Amazon.com, Inc.1,457,055$1.23M0.05%00.0%Unchanged
Comprehensive Financial Management LLC2,207,619$1.87M0.05%00.0%Unchanged
Vanguard Group Inc2,431,829$2.05M0.00%−53,252−2.1%Reduced
Madrona Venture Group, LLC6,020,770$5.09M36.76%00.0%Unchanged
Cercano Management LLC7,172,985$6.06M0.23%00.0%Unchanged
Perceptive Advisors LLC12,594,211$10.6M0.31%00.0%Unchanged
AH Capital Management, L.L.C.17,653,917$14.9M1.07%00.0%Unchanged
Botty Investors LLC0$00.00%−622,409−100.0%Sold out
Sentinel Trust Co Lba0$00.00%−280,000−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−224,456−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−147,497−100.0%Sold out
MYDA Advisors LLC0$00.00%−76,413−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−71,301−100.0%Sold out
Jain Global LLC0$00.00%−45,100−100.0%Sold out
AQR Capital Management LLC0$00.00%−42,092−100.0%Sold out
Ground Swell Capital, LLC0$00.00%−20,061−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−283−100.0%Sold out
Essential Partners LLC0$00.00%−23−100.0%Sold out
Simplex Trading, LLC0$00.00%−115−100.0%Sold out