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Mereo BioPharma Group plc

MREO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001719714

No open-market purchases or sales by Mereo BioPharma Group plc insiders were filed in the last 90 days; 60 institutions reported holding it in 13F filings for Q2 2026, worth $18.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Mereo BioPharma Group plc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
70
−13 vs. Q3 2025
Shares held
62.0M
−38.2M (−38.1%) vs. Q3 2025
Total value
$25.8M
−$180.8M (−87.5%) vs. Q3 2025
New holders
22
15 more added
Sold out
35
20 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MREO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 70 institutions
Q1 2021: 67 institutionsQ2 2021: 72 institutionsQ3 2021: 63 institutionsQ4 2021: 73 institutionsQ1 2022: 60 institutionsQ2 2022: 64 institutionsQ3 2022: 63 institutionsQ4 2022: 61 institutionsQ1 2023: 58 institutionsQ2 2023: 53 institutionsQ3 2023: 56 institutionsQ4 2023: 64 institutionsQ1 2024: 80 institutionsQ2 2024: 79 institutionsQ3 2024: 77 institutionsQ4 2024: 91 institutionsQ1 2025: 90 institutionsQ2 2025: 86 institutionsQ3 2025: 84 institutionsQ4 2025: 70 institutionsQ1 2026: 63 institutionsQ2 2026: 60 institutions
Value heldQ4 2025: $25.8M
Q1 2021: $304.5MQ2 2021: $284.4MQ3 2021: $212.2MQ4 2021: $145.7MQ1 2022: $99.9MQ2 2022: $82.7MQ3 2022: $58.5MQ4 2022: $46.2MQ1 2023: $43.0MQ2 2023: $84.3MQ3 2023: $90.4MQ4 2023: $181.4MQ1 2024: $277.3MQ2 2024: $361.9MQ3 2024: $434.8MQ4 2024: $403.1MQ1 2025: $250.3MQ2 2025: $267.8MQ3 2025: $206.7MQ4 2025: $25.8MQ1 2026: $24.9MQ2 2026: $18.0M
Institutions holding MREO and their total value by quarter
QuarterHoldersValue
Q2 202660$18.0M
Q1 202663$24.9M
Q4 202570$25.8M
Q3 202584$206.7M
Q2 202586$267.8M
Q1 202590$250.3M
Q4 202491$403.1M
Q3 202477$434.8M
Q2 202479$361.9M
Q1 202480$277.3M
Q4 202364$181.4M
Q3 202356$90.4M
Q2 202353$84.3M
Q1 202358$43.0M
Q4 202261$46.2M
Q3 202263$58.5M
Q2 202264$82.7M
Q1 202260$99.9M
Q4 202173$145.7M
Q3 202163$212.2M
Q2 202172$284.4M
Q1 202167$304.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Mereo BioPharma Group plc; share changes are against Q3 2025.

Institutions holding MREO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rubric Capital Management LP15,307,347$6.38M0.08%00.0%Unchanged
683 Capital Management, LLC15,025,000$6.26M0.52%+10,150,000+208.2%Added
EcoR1 Capital, LLC7,856,466$3.27M0.15%+7,856,466New
Schonfeld Strategic Advisors LLC6,090,381$2.54M0.01%+4,357,657+251.5%Added
Tejara Capital Ltd2,159,681$899.9K0.37%+252,837+13.3%Added
Logos Global Management LP1,850,000$770.9K0.05%+1,350,000+270.0%Added
UBS Asset Management Americas Inc1,763,666$735.4K0.00%−143,109−7.5%Reduced
Monaco Asset Management SAM1,585,214$660.6K0.20%+639,299+67.6%Added
UBS Group AG1,558,931$650.1K0.00%+588,264+60.6%Added
Balyasny Asset Management LLC1,280,275$533.5K0.00%+1,280,275New
Morgan Stanley1,273,785$530.8K0.00%−2,072,562−61.9%Reduced
Two Sigma Investments, LP525,125$218.8K0.00%−562,971−51.7%Reduced
Group One Trading, L.P.441,636$184.0K0.01%+305,048+223.3%Added
Simplex Trading, LLC419,477$174.9K0.00%+223,208+113.7%Added
EntryPoint Capital, LLC400,700$167.0K0.07%+400,700New
Luminus Management LLC395,000$164.6K0.15%+395,000New
Rangeley Capital, LLC364,000$151.7K0.13%+364,000New
Jane Street Group, LLC356,004$148.3K0.00%−96,358−21.3%Reduced
BlackRock, Inc.312,613$130.3K0.00%−131,391−29.6%Reduced
Knott David M Jr300,337$125.2K0.06%00.0%Unchanged
Quadrature Capital Ltd266,731$111.1K0.00%+266,731New
Sphera Funds Management Ltd.255,400$106.4K0.02%+255,400New
Two Sigma Advisers, LP251,900$105.0K0.00%+9,700+4.0%Added
Newtyn Management, LLC224,622$93.6K0.01%+224,622New
Citigroup Inc195,814$81.6K0.00%+195,814New
Renaissance Technologies LLC194,371$81.0K0.00%−396,500−67.1%Reduced
ADAR1 Capital Management, LLC150,000$62.5K0.00%+150,000New
State Street Corp130,643$54.4K0.00%−2,058−1.6%Reduced
Virtus Investment Advisers, Inc.122,595$51.1K0.01%+81,665+199.5%Added
Graham Capital Management, L.P.116,286$48.5K0.00%+116,286New
Geode Capital Management, LLC92,534$38.6K0.00%00.0%Unchanged
Millennium Management LLC83,646$34.9K0.00%−253,857−75.2%Reduced
Baader Bank INC128,742$33.1K0.00%+128,742New
Acadian Asset Management LLC61,435$24.0K0.00%−194,943−76.0%Reduced
Caption Management, LLC50,000$20.8K0.00%−139,914−73.7%Reduced
Engineers Gate Manager LP49,798$20.8K0.00%+49,798New
Clear Harbor Asset Management, LLC35,000$14.6K0.00%−42,000−54.5%Reduced
Forefront Analytics, LLC31,768$13.2K0.01%−1,412−4.3%Reduced
Goldman Sachs Group Inc28,026$11.7K0.00%−2,335,998−98.8%Reduced
Bank of America Corp25,492$10.6K0.00%−413,130−94.2%Reduced
Centiva Capital, LP25,000$10.4K0.00%00.0%Unchanged
Significant Wealth Partners LLC21,689$9.04K0.01%−26,125−54.6%Reduced
Aquatic Capital Management LLC21,216$8.84K0.00%−32,496−60.5%Reduced
SmartHarvest Portfolios, LLC20,290$8.46K0.00%+20,290New
Rhumbline Advisers19,146$7.98K0.00%+10,024+109.9%Added
Blue Rock Wealth Management LLC19,000$7.92K0.00%−18,000−48.6%Reduced
Resources Investment Advisors, LLC.18,300$7.63K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.17,000$7.08K0.00%+4,000+30.8%Added
PFG Investments, LLC16,650$6.94K0.00%−500−2.9%Reduced
Barclays PLC14,500$6.04K0.00%+14,500New
QRG Capital Management, Inc.13,503$5.63K0.00%+13,503New
AE Wealth Management LLC12,563$5.24K0.00%+12,563New
MML Investors Services, LLC12,200$5.08K0.00%+12,200New
Astoria Portfolio Advisors LLC.10,000$4.03K0.00%+10,000New
GAMMA Investing LLC9,561$3.98K0.00%+380+4.1%Added
Toronto Dominion Bank5,500$2.29K0.00%+5,500New
SRS Capital Advisors, Inc.4,000$1.67K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd2,231$9300.00%−6,245−73.7%Reduced
Rockefeller Capital Management L.P.2,000$8330.00%00.0%Unchanged
Wells Fargo & Company1,737$7240.00%+1,507+655.2%Added
Allworth Financial LP1,611$6720.00%+38+2.4%Added
Advisor Group Holdings, Inc.500$2080.00%−5,177−91.2%Reduced
EverSource Wealth Advisors, LLC417$1740.00%00.0%Unchanged
MAI Capital Management309$1290.00%00.0%Unchanged
New England Capital Financial Advisors LLC300$1260.00%00.0%Unchanged
SageView Advisory Group, LLC161$680.00%+161New
Farther Finance Advisors, LLC17$70.00%+17New
US Bancorp13$50.00%00.0%Unchanged
BNP Paribas Arbitrage, SA3$10.00%00.0%Unchanged
Sit Investment Associates Inc970$00.00%00.0%Unchanged
Janus Henderson Group PLC0$00.00%−16,290,130−100.0%Sold out
Frazier Life Sciences Management, L.P.0$00.00%−9,440,112−100.0%Sold out
Mangrove Partners0$00.00%−7,790,580−100.0%Sold out
Standard Life Aberdeen plc0$00.00%−5,538,699−100.0%Sold out
Rock Springs Capital Management LP0$00.00%−4,570,649−100.0%Sold out
Clearline Capital LP0$00.00%−3,834,163−100.0%Sold out
Alkeon Capital Management LLC0$00.00%−3,698,100−100.0%Sold out
Citadel Advisors LLC0$00.00%−3,171,632−100.0%Sold out
FMR LLC0$00.00%−1,454,900−100.0%Sold out
Blue Owl Capital Holdings LP0$00.00%−1,250,000−100.0%Sold out
HealthInvest Partners AB0$00.00%−764,901−100.0%Sold out
Marshall Wace, LLP0$00.00%−767,744−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−493,378−100.0%Sold out
Artia Global Partners LP0$00.00%−475,361−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−299,711−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−265,000−100.0%Sold out
Knoll Capital Management, LLC0$00.00%−260,470−100.0%Sold out
XTX Topco Ltd0$00.00%−191,037−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−110,000−100.0%Sold out
Nomura Holdings Inc0$00.00%−103,800−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−58,145−100.0%Sold out
Avanza Fonder AB0$00.00%−38,235−100.0%Sold out
HRT Financial LP0$00.00%−34,852−100.0%Sold out
Forefront Wealth Partners, LLC0$00.00%−33,180−100.0%Sold out
Squarepoint Ops LLC0$00.00%−30,055−100.0%Sold out
Federation des caisses Desjardins du Quebec0$00.00%−21,271−100.0%Sold out
Golden State Equity Partners0$00.00%−19,900−100.0%Sold out
Virtu Financial LLC0$00.00%−15,970−100.0%Sold out
State of New Jersey Common Pension Fund D0$00.00%−15,644−100.0%Sold out
Scientech Research LLC0$00.00%−10,124−100.0%Sold out