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Mereo BioPharma Group plc

MREO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001719714

No open-market purchases or sales by Mereo BioPharma Group plc insiders were filed in the last 90 days; 60 institutions reported holding it in 13F filings for Q2 2026, worth $18.0M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Mereo BioPharma Group plc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
84
−2 vs. Q2 2025
Shares held
100.2M
+1.49M (+1.5%) vs. Q2 2025
Total value
$206.7M
−$61.1M (−22.8%) vs. Q2 2025
New holders
14
23 more added
Sold out
16
23 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MREO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 84 institutions
Q1 2021: 67 institutionsQ2 2021: 72 institutionsQ3 2021: 63 institutionsQ4 2021: 73 institutionsQ1 2022: 60 institutionsQ2 2022: 64 institutionsQ3 2022: 63 institutionsQ4 2022: 61 institutionsQ1 2023: 58 institutionsQ2 2023: 53 institutionsQ3 2023: 56 institutionsQ4 2023: 64 institutionsQ1 2024: 80 institutionsQ2 2024: 79 institutionsQ3 2024: 77 institutionsQ4 2024: 91 institutionsQ1 2025: 90 institutionsQ2 2025: 86 institutionsQ3 2025: 84 institutionsQ4 2025: 70 institutionsQ1 2026: 63 institutionsQ2 2026: 60 institutions
Value heldQ3 2025: $206.7M
Q1 2021: $304.5MQ2 2021: $284.4MQ3 2021: $212.2MQ4 2021: $145.7MQ1 2022: $99.9MQ2 2022: $82.7MQ3 2022: $58.5MQ4 2022: $46.2MQ1 2023: $43.0MQ2 2023: $84.3MQ3 2023: $90.4MQ4 2023: $181.4MQ1 2024: $277.3MQ2 2024: $361.9MQ3 2024: $434.8MQ4 2024: $403.1MQ1 2025: $250.3MQ2 2025: $267.8MQ3 2025: $206.7MQ4 2025: $25.8MQ1 2026: $24.9MQ2 2026: $18.0M
Institutions holding MREO and their total value by quarter
QuarterHoldersValue
Q2 202660$18.0M
Q1 202663$24.9M
Q4 202570$25.8M
Q3 202584$206.7M
Q2 202586$267.8M
Q1 202590$250.3M
Q4 202491$403.1M
Q3 202477$434.8M
Q2 202479$361.9M
Q1 202480$277.3M
Q4 202364$181.4M
Q3 202356$90.4M
Q2 202353$84.3M
Q1 202358$43.0M
Q4 202261$46.2M
Q3 202263$58.5M
Q2 202264$82.7M
Q1 202260$99.9M
Q4 202173$145.7M
Q3 202163$212.2M
Q2 202172$284.4M
Q1 202167$304.5M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Mereo BioPharma Group plc; share changes are against Q2 2025.

Institutions holding MREO in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC16,290,130$33.6M0.02%−1,398,462−7.9%Reduced
Rubric Capital Management LP15,307,347$31.5M0.42%00.0%Unchanged
Frazier Life Sciences Management, L.P.9,440,112$19.4M0.58%00.0%Unchanged
Mangrove Partners7,790,580$16.0M1.33%−845,905−9.8%Reduced
Standard Life Aberdeen plc5,538,699$11.4M0.02%+2,509,827+82.9%Added
683 Capital Management, LLC4,875,000$10.0M0.91%+525,000+12.1%Added
Rock Springs Capital Management LP4,570,649$9.42M0.55%+105,357+2.4%Added
Clearline Capital LP3,834,163$7.90M0.68%+216,000+6.0%Added
Alkeon Capital Management LLC3,698,100$7.62M0.03%−1,000,000−21.3%Reduced
Morgan Stanley3,346,347$6.89M0.00%+2,560,970+326.1%Added
Citadel Advisors LLC3,171,632$6.53M0.01%+2,410,973+317.0%Added
Goldman Sachs Group Inc2,364,024$4.87M0.00%−726,044−23.5%Reduced
Tejara Capital Ltd1,906,844$3.93M2.15%−523,593−21.5%Reduced
UBS Asset Management Americas Inc1,906,775$3.93M0.00%+1,906,775New
Schonfeld Strategic Advisors LLC1,732,724$3.57M0.02%+823,084+90.5%Added
FMR LLC1,454,900$3.00M0.00%−23,600−1.6%Reduced
Blue Owl Capital Holdings LP1,250,000$2.58M0.80%+1,250,000New
Two Sigma Investments, LP1,088,096$2.24M0.00%+428,938+65.1%Added
UBS Group AG970,667$2.00M0.00%+597,162+159.9%Added
Monaco Asset Management SAM945,915$1.95M0.73%+550,915+139.5%Added
HealthInvest Partners AB764,901$1.67M0.62%00.0%Unchanged
Marshall Wace, LLP767,744$1.58M0.00%00.0%Unchanged
Renaissance Technologies LLC590,871$1.22M0.00%−889,600−60.1%Reduced
Logos Global Management LP500,000$1.03M0.10%+500,000New
Susquehanna International Group, LLP493,378$1.02M0.00%+131,836+36.5%Added
Artia Global Partners LP475,361$979.2K0.17%00.0%Unchanged
Jane Street Group, LLC452,362$931.9K0.00%+204,921+82.8%Added
BlackRock, Inc.444,004$914.6K0.00%−11,361−2.5%Reduced
Bank of America Corp438,622$903.6K0.00%−390.0%Reduced
Millennium Management LLC337,503$695.3K0.00%−258,170−43.3%Reduced
Knott David M Jr300,337$618.7K0.26%−19,000−5.9%Reduced
Soleus Capital Management, L.P.299,711$617.4K0.03%−300,000−50.0%Reduced
Hudson Bay Capital Management LP265,000$545.9K0.00%−185,000−41.1%Reduced
Knoll Capital Management, LLC260,470$536.6K0.29%00.0%Unchanged
Acadian Asset Management LLC256,378$522.0K0.00%+256,378New
Two Sigma Advisers, LP242,200$498.9K0.00%+97,600+67.5%Added
Simplex Trading, LLC196,269$404.0K0.01%−4,872−2.4%Reduced
XTX Topco Ltd191,037$393.5K0.02%+121,696+175.5%Added
Caption Management, LLC189,914$391.2K0.02%−7,685−3.9%Reduced
Group One Trading, L.P.136,588$281.4K0.01%−2,971−2.1%Reduced
State Street Corp132,701$273.4K0.00%+87,759+195.3%Added
Cantor Fitzgerald, L. P.110,000$226.6K0.00%−232,957−67.9%Reduced
Nomura Holdings Inc103,800$213.8K0.00%−21,200−17.0%Reduced
Geode Capital Management, LLC92,534$190.6K0.00%00.0%Unchanged
Clear Harbor Asset Management, LLC77,000$158.6K0.01%+35,000+83.3%Added
Gsa Capital Partners LLP58,145$120.0K0.01%+58,145New
Aquatic Capital Management LLC53,712$110.6K0.00%+26,782+99.5%Added
Significant Wealth Partners LLC47,814$98.5K0.05%+25,553+114.8%Added
Virtus Investment Advisers, Inc.40,930$84.3K0.02%+7,105+21.0%Added
Avanza Fonder AB38,235$78.8K0.00%00.0%Unchanged
Blue Rock Wealth Management LLC37,000$76.2K0.05%00.0%Unchanged
HRT Financial LP34,852$71.0K0.00%+34,852New
Forefront Analytics, LLC33,180$68.4K0.07%+14,042+73.4%Added
Forefront Wealth Partners, LLC33,180$68.4K0.02%+33,180New
Squarepoint Ops LLC30,055$61.9K0.00%+9,387+45.4%Added
Centiva Capital, LP25,000$51.5K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec21,271$43.8K0.00%+21,271New
Golden State Equity Partners19,900$41.0K0.01%00.0%Unchanged
Resources Investment Advisors, LLC.18,300$37.7K0.00%00.0%Unchanged
PFG Investments, LLC17,150$35.3K0.00%−20,283−54.2%Reduced
Sheets Smith Investment Management16,890$34.8K0.02%00.0%Unchanged
Virtu Financial LLC15,970$33.0K0.00%+15,970New
State of New Jersey Common Pension Fund D15,644$32.2K0.00%+15,644New
Newbridge Financial Services Group, Inc.13,000$26.8K0.00%00.0%Unchanged
Scientech Research LLC10,124$20.9K0.01%+10,124New
Level Four Advisory Services, LLC10,000$20.6K0.00%00.0%Unchanged
GAMMA Investing LLC9,181$18.9K0.00%−76−0.8%Reduced
Rhumbline Advisers9,122$18.8K0.00%−756−7.7%Reduced
Caitong International Asset Management Co., Ltd8,476$17.5K0.01%+3,932+86.5%Added
Advisor Group Holdings, Inc.5,677$9.71K0.00%+300+5.6%Added
SRS Capital Advisors, Inc.4,000$8.24K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.2,000$4.12K0.00%+2,000New
Allworth Financial LP1,573$3.24K0.00%−64−3.9%Reduced
GPS Wealth Strategies Group, LLC1,500$3.09K0.00%00.0%Unchanged
Wealthspire Advisors, LLC1,026$2.11K0.00%+1,026New
Sit Investment Associates Inc970$2.00K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC417$8590.00%−53−11.3%Reduced
MAI Capital Management309$6370.00%00.0%Unchanged
New England Capital Financial Advisors LLC300$6180.00%00.0%Unchanged
Wells Fargo & Company230$4730.00%00.0%Unchanged
Principal Securities, Inc.75$1550.00%00.0%Unchanged
US Bancorp13$270.00%00.0%Unchanged
BNP Paribas Arbitrage, SA3$60.00%00.0%Unchanged
Royal Bank of Canada5$00.00%+5New
Deerfield Management Company, L.P. (Series C)0$00.00%−6,710,429−100.0%Sold out
Paloma Partners Management Co0$00.00%−296,659−100.0%Sold out
Dauntless Investment Group, LLC0$00.00%−134,122−100.0%Sold out
NEOS Investment Management LLC0$00.00%−102,583−100.0%Sold out
Tema ETFs LLC0$00.00%−102,583−100.0%Sold out
Leonteq Securities AG0$00.00%−100,000−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−59,200−100.0%Sold out
J. Goldman & Co LP0$00.00%−52,384−100.0%Sold out
Quadrature Capital Ltd0$00.00%−25,399−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−21,176−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−21,099−100.0%Sold out
Marex Group plc0$00.00%−10,000−100.0%Sold out
Raymond James Financial Inc0$00.00%−1,570−100.0%Sold out
Skopos Labs, Inc.0$00.00%−849−100.0%Sold out
Signaturefd, LLC0$00.00%−187−100.0%Sold out
Transce3nd, LLC0$00.00%−127−100.0%Sold out