| Sep 18, 2026 (view filing)4:15 PM ET | Sep 16 | 2 days | Hanson KristopherGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −16.5K | $11.67 | −$192.7K | −10.8%137.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 18, 2026 (view filing)6:55 PM ET | Aug 14 | 4 days | Catalyst4, Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +4.40M | $11.38 | +$50.1M | +21.0%25.3M after | |
| Aug 18, 2026 (view filing)6:55 PM ET | Aug 14 | 4 days | Catalyst4, Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +2.93M | $11.38 | +$33.3M | –2.93M after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity. |
| Aug 4, 2026 (view filing)8:39 PM ET | Aug 3 | 1 day | Lillie James WoodruffChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −22.1K | $12.54 | −$276.9K | −9.8%202.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 30, 2026 (view filing)6:39 PM ET | Jul 28-30 | 2 days | Catalyst4, Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +1.21M | $12.66 | +$15.3M | +6.1%20.9M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 28, 2026 (view filing)9:14 PM ET | Jul 28 | Same day | Cox TroyDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +15.6K | $9.52 | +$148.7K | New position15.6K after | |
| Jul 20, 2026 (view filing)6:00 AM ET | Jul 15-17 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Gillis JonathanCAO and Interim CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −37.0K | $37.12 | −$1.37M | −20.4%144.2K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 20, 2026 (view filing)6:00 AM ET | Jul 15-17 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Kreitzer AnatolChief Discovery Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −36.3K | $37.09 | −$1.35M | −17.2%174.9K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 17, 2026 (view filing)9:46 PM ET | Jul 15-17 | 2 days | Kroeger Christopher A.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −147.6K | $36.87 | −$5.44M | −10.6%1.25M after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 17, 2026 (view filing)9:45 PM ET | Jul 15-17 | 2 days | Lillie James WoodruffChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −18.3K | $36.88 | −$673.6K | −7.5%224.5K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 17, 2026 (view filing)9:44 PM ET | Jul 15-17 | 2 days | Hanson KristopherGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −16.5K | $36.82 | −$607.9K | −10.2%145.8K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 17, 2026 (view filing)9:43 PM ET | Jul 15-17 | 2 days | Foff Erin PennockChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −47.2K | $36.78 | −$1.73M | −13.6%298.9K after | 9 lotsThis row combines 9 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 18, 2026 (view filing) | May 18 | Same day | Kroeger Christopher A.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −118.2K | $27.19 | −$3.21M | −7.8%1.39M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 11, 2026 (view filing) | May 7 | 4 days | Foff Erin PennockChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −4.44K | $28.54 | −$126.6K | −1.3%346.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 11, 2026 (view filing) | May 11 | Same day | Hanson KristopherGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −13.9K | $30.13 | −$419.3K | −7.9%162.3K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 11, 2026 (view filing) | May 7 | 4 days | Lillie James WoodruffChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −721 | $28.28 | −$20.4K | −0.3%242.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 11, 2026 (view filing) | May 7-11 | 4 days | Kroeger Christopher A.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −68.5K | $28.47 | −$1.95M | −4.3%1.51M after | 9 lotsThis row combines 9 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4-6 | 2 days | Setia VishwasChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −36.4K | $28.17 | −$1.02M | −9.3%356.3K after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4-6 | 2 days | Foff Erin PennockChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −50.3K | $28.39 | −$1.43M | −12.5%350.5K after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4 | 2 days | Hanson KristopherGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −13.9K | $27.89 | −$388.2K | −7.3%176.2K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4-6 | 2 days | Lillie James WoodruffChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −51.7K | $28.40 | −$1.47M | −17.5%243.4K after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4-6 | 2 days | Kroeger Christopher A.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −49.7K | $28.39 | −$1.41M | −3.1%1.58M after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 29, 2026 (view filing) | Apr 27 | 2 days | Kreitzer AnatolChief Discovery Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −45.4K | $29.66 | −$1.35M | −17.7%211.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 29, 2026 (view filing) | Apr 27-28 | 2 days | Gillis JonathanCAAO and PAO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −69.8K | $29.89 | −$2.09M | −27.8%181.2K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 17, 2026 (view filing) | Apr 15-16 | 2 days | Setia VishwasChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −2.92K | $26.89 | −$78.6K | −0.7%392.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 17, 2026 (view filing) | Apr 15 | 2 days | Kreitzer AnatolChief Discovery Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −3.32K | $26.61 | −$88.2K | −1.3%256.6K after | |
| Apr 17, 2026 (view filing) | Apr 15-16 | 2 days | Foff Erin PennockChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −3.21K | $27.03 | −$86.9K | −0.8%400.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 17, 2026 (view filing) | Apr 15 | 2 days | Malenka Robert C.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −8.59K | $26.90 | −$231.2K | −2.6%316.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 17, 2026 (view filing) | Apr 15-16 | 2 days | Hanson KristopherGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −1.83K | $26.89 | −$49.1K | −1.0%190.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 17, 2026 (view filing) | Apr 15-16 | 2 days | Lillie James WoodruffChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −4.51K | $27.16 | −$122.6K | −1.5%295.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 17, 2026 (view filing) | Apr 15 | 2 days | Gillis JonathanCAAO and PAO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −3.59K | $26.61 | −$95.5K | −1.4%251.1K after | |
| Apr 17, 2026 (view filing) | Apr 15-16 | 2 days | Kroeger Christopher A.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −19.2K | $27.16 | −$521.1K | −1.2%1.63M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 24, 2026 (view filing) | Feb 20-24 | 4 days | Malenka Robert C.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −14.2K | $18.34 | −$260.4K | −4.2%325.1K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 20, 2026 (view filing) | Feb 18-20 | 2 days | Pavlov GeorgeDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +25.0K | $17.65 | +$441.2K | New position25.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Malenka Robert C.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −12.1K | $18.21 | −$220.6K | −3.4%339.3K after | |
| Feb 12, 2026 (view filing) | Feb 10-11 | 2 days | Malenka Robert C.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −6.86K | $18.12 | −$124.3K | −1.9%351.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 12, 2026 (view filing) | Feb 10 | 2 days | Garnett Timothy JohnDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +14.1K | $17.89 | +$252.7K | New position14.1K after | |
| Feb 4, 2026 (view filing) | Feb 2-3 | 2 days | Malenka Robert C.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −7.04K | $18.02 | −$126.9K | −1.9%358.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 30, 2026 (view filing) | Jan 28-30 | 2 days | Malenka Robert C.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Voting Common Stock | −34.4K | $18.49 | −$635.9K | −8.6%365.3K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 30, 2025 (view filing) | Oct 28 | 2 days | Novo Holdings A/S10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +952.9K | $17.00 | +$16.2M | +34.9%3.69M after | |
| Oct 29, 2025 (view filing) | Oct 28 | 1 day | Catalyst4, Inc.10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Voting Common Stock | +5.44M | $17.00 | +$92.5M | +38.2%19.7M after | |
