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Mineralys Therapeutics, Inc.

MLYS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001933414

In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Mineralys Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
166
+18 vs. Q1 2025
Shares held
65.7M
+4.84M (+7.9%) vs. Q1 2025
Total value
$888.8M
−$77.4M (−8.0%) vs. Q1 2025
New holders
42
75 more added
Sold out
24
30 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 166 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 68 institutionsQ2 2023: 68 institutionsQ3 2023: 77 institutionsQ4 2023: 87 institutionsQ1 2024: 92 institutionsQ2 2024: 94 institutionsQ3 2024: 106 institutionsQ4 2024: 109 institutionsQ1 2025: 149 institutionsQ2 2025: 166 institutionsQ3 2025: 193 institutionsQ4 2025: 223 institutionsQ1 2026: 215 institutionsQ2 2026: 225 institutions
Value heldQ2 2025: $888.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $385.4MQ2 2023: $429.2MQ3 2023: $252.1MQ4 2023: $298.5MQ1 2024: $540.6MQ2 2024: $516.6MQ3 2024: $540.1MQ4 2024: $572.2MQ1 2025: $966.2MQ2 2025: $888.8MQ3 2025: $3.01BQ4 2025: $3.21BQ1 2026: $2.46BQ2 2026: $2.69B
Institutions holding MLYS and their total value by quarter
QuarterHoldersValue
Q2 2026225$2.69B
Q1 2026215$2.46B
Q4 2025223$3.21B
Q3 2025193$3.01B
Q2 2025166$888.8M
Q1 2025149$966.2M
Q4 2024109$572.2M
Q3 2024106$540.1M
Q2 202494$516.6M
Q1 202492$540.6M
Q4 202387$298.5M
Q3 202377$252.1M
Q2 202368$429.2M
Q1 202368$385.4M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding MLYS in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Federated Hermes, Inc.16,528$223.6K0.00%+4,577+38.3%Added
Letko, Brosseau & Associates Inc16,500$223.2K0.00%00.0%Unchanged
Fox Run Management, L.L.C.16,243$219.8K0.04%+16,243New
Cinctive Capital Management LP16,113$218.0K0.01%+1,894+13.3%Added
Bellevue Group AG15,556$210.5K0.00%−943−5.7%Reduced
STRS Ohio15,400$208.4K0.00%−7,200−31.9%Reduced
Quest Partners LLC14,841$200.8K0.02%−1,084−6.8%Reduced
Manufacturers Life Insurance Company, The14,775$199.9K0.00%+3,390+29.8%Added
Citadel Advisors LLC14,382$194.6K0.00%−129,980−90.0%Reduced
Quantinno Capital Management LP13,597$184.0K0.00%+859+6.7%Added
China Universal Asset Management Co., Ltd.13,090$177.1K0.02%+3,094+31.0%Added
Allianz Asset Management GmbH12,300$166.4K0.00%+12,300New
Profund Advisors LLC12,131$164.1K0.01%+12,131New
Quadrature Capital Ltd11,987$162.4K0.00%−61,021−83.6%Reduced
Janus Henderson Group PLC11,600$157.1K0.00%+11,600New
Squarepoint Ops LLC11,515$155.8K0.00%+11,515New
Change Path, LLC10,750$145.4K0.00%00.0%Unchanged
ProShare Advisors LLC10,457$141.5K0.00%+10,457New
Group One Trading, L.P.10,137$137.2K0.00%−2,567−20.2%Reduced
HRT Financial LP10,077$136.0K0.00%+10,077New
Greenland Capital Management LP10,000$135.3K0.02%−10,000−50.0%Reduced
Royal Bank of Canada9,563$130.0K0.00%+8,264+636.2%Added
Police & Firemen's Retirement System of New Jersey9,234$124.9K0.00%+2,098+29.4%Added
New York State Common Retirement Fund7,764$105.0K0.00%00.0%Unchanged
KLP Kapitalforvaltning AS6,700$90.7K0.00%+6,700New
Virtus Investment Advisers, Inc.6,302$85.3K0.03%−7,192−53.3%Reduced
CWM, LLC6,251$85.0K0.00%−2,091−25.1%Reduced
BNP Paribas Arbitrage, SA4,108$55.6K0.00%−57,085−93.3%Reduced
Ameritas Investment Partners, Inc.3,995$54.1K0.00%+1,197+42.8%Added
Tower Research Capital LLC (TRC)2,749$37.2K0.00%+1,575+134.2%Added
Mirae Asset Global Investments Co., Ltd.2,518$34.1K0.00%+850+51.0%Added
The PNC Financial Services Group, Inc.2,234$30.2K0.00%+28+1.3%Added
Nisa Investment Advisors, LLC2,065$27.9K0.00%+458+28.5%Added
SBI Securities Co., Ltd.1,724$23.3K0.00%+134+8.4%Added
FNY Investment Advisers, LLC1,500$20.0K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.1,325$18.1K0.00%+1,325New
GF Fund Management Co. Ltd.1,274$17.2K0.00%00.0%Unchanged
Amalgamated Bank985$13.0K0.00%00.0%Unchanged
Comerica Bank803$10.9K0.00%+206+34.5%Added
Covestor Ltd739$10.0K0.01%+739New
Versant Capital Management, Inc513$6.94K0.00%+82+19.0%Added
GAMMA Investing LLC437$5.91K0.00%−119−21.4%Reduced
EverSource Wealth Advisors, LLC357$4.83K0.00%+341+2,131.3%Added
Smartleaf Asset Management LLC341$4.67K0.00%−583−63.1%Reduced
Massmutual Trust Co FSB319$4.32K0.00%00.0%Unchanged
Daiwa Securities Group Inc.234$3.00K0.00%+82+53.9%Added
Caitong International Asset Management Co., Ltd192$2.60K0.00%+192New
US Bancorp174$2.35K0.00%+60+52.6%Added
Raymond James Financial Inc141$1.91K0.00%+141New
Sterling Capital Management LLC95$1.28K0.00%−297−75.8%Reduced
True Wealth Design, LLC76$1.03K0.00%+76New
Rothschild Investment LLC75$1.01K0.00%+35+87.5%Added
Avion Wealth78$1.00K0.00%00.0%Unchanged
Rise Advisors, LLC62$8390.00%+62New
Fifth Third Bancorp61$8250.00%+61New
Private Wealth Management Group, LLC50$6770.00%00.0%Unchanged
IFP Advisors, Inc0$6630.00%0Unchanged
Parkside Financial Bank & Trust35$4740.00%+35New
Allworth Financial LP34$4610.00%−56−62.2%Reduced
Russell Investments Group, Ltd.23$3110.00%+23New
Parallel Advisors, LLC22$2980.00%00.0%Unchanged
MAI Capital Management18$2440.00%+18New
Farther Finance Advisors, LLC17$2300.00%00.0%Unchanged
National Bank of Canada7$950.00%+7New
Larson Financial Group LLC6$810.00%+6New
Essential Partners LLC1$140.00%+1New
TCG Crossover Management, LLC0$00.00%−2,470,265−100.0%Sold out
Findell Capital Management LLC0$00.00%−400,000−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−279,500−100.0%Sold out
EAM Investors, LLC0$00.00%−164,273−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−112,500−100.0%Sold out
Monashee Investment Management LLC0$00.00%−112,457−100.0%Sold out
Schroder Investment Management Group0$00.00%−62,893−100.0%Sold out
Weiss Asset Management LP0$00.00%−50,000−100.0%Sold out
Two Sigma Investments, LP0$00.00%−48,532−100.0%Sold out
Jain Global LLC0$00.00%−43,765−100.0%Sold out
Alps Advisors Inc0$00.00%−34,664−100.0%Sold out
Simplex Trading, LLC0$00.00%−25,543−100.0%Sold out
Virtu Financial LLC0$00.00%−25,203−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−20,130−100.0%Sold out
Martingale Asset Management L P0$00.00%−14,960−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−13,989−100.0%Sold out
XTX Topco Ltd0$00.00%−13,785−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−11,175−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−10,375−100.0%Sold out
Quarry LP0$00.00%−7,000−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−779−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−112−100.0%Sold out
Skopos Labs, Inc.0$00.00%−26−100.0%Sold out
Signaturefd, LLC0$00.00%−22−100.0%Sold out
Lindbrook Capital, LLC––––Not filed