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LENZ Therapeutics, Inc.

LENZ
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001815776

No open-market purchases or sales by LENZ Therapeutics, Inc. insiders were filed in the last 90 days; 145 institutions reported holding it in 13F filings for Q2 2026, worth $197.3M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in LENZ Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
−5 vs. Q3 2025
Shares held
35.1M
+5.93M (+20.4%) vs. Q3 2025
Total value
$561.6M
−$794.0M (−58.6%) vs. Q3 2025
New holders
50
53 more added
Sold out
55
33 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LENZ on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 161 institutions
Q1 2021: 0 institutionsQ2 2021: 51 institutionsQ3 2021: 60 institutionsQ4 2021: 58 institutionsQ1 2022: 63 institutionsQ2 2022: 63 institutionsQ3 2022: 63 institutionsQ4 2022: 66 institutionsQ1 2023: 62 institutionsQ2 2023: 66 institutionsQ3 2023: 67 institutionsQ4 2023: 63 institutionsQ1 2024: 55 institutionsQ2 2024: 65 institutionsQ3 2024: 78 institutionsQ4 2024: 95 institutionsQ1 2025: 105 institutionsQ2 2025: 114 institutionsQ3 2025: 166 institutionsQ4 2025: 161 institutionsQ1 2026: 146 institutionsQ2 2026: 145 institutions
Value heldQ4 2025: $561.6M
Q1 2021: $0Q2 2021: $981.4MQ3 2021: $587.4MQ4 2021: $431.7MQ1 2022: $185.7MQ2 2022: $83.0MQ3 2022: $93.9MQ4 2022: $95.6MQ1 2023: $72.9MQ2 2023: $81.2MQ3 2023: $75.8MQ4 2023: $81.5MQ1 2024: $362.0MQ2 2024: $327.0MQ3 2024: $444.8MQ4 2024: $573.2MQ1 2025: $541.8MQ2 2025: $725.1MQ3 2025: $1.36BQ4 2025: $561.6MQ1 2026: $303.3MQ2 2026: $197.3M
Institutions holding LENZ and their total value by quarter
QuarterHoldersValue
Q2 2026145$197.3M
Q1 2026146$303.3M
Q4 2025161$561.6M
Q3 2025166$1.36B
Q2 2025114$725.1M
Q1 2025105$541.8M
Q4 202495$573.2M
Q3 202478$444.8M
Q2 202465$327.0M
Q1 202455$362.0M
Q4 202363$81.5M
Q3 202367$75.8M
Q2 202366$81.2M
Q1 202362$72.9M
Q4 202266$95.6M
Q3 202263$93.9M
Q2 202263$83.0M
Q1 202263$185.7M
Q4 202158$431.7M
Q3 202160$587.4M
Q2 202151$981.4M
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding LENZ Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding LENZ in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Knott David M Jr53,732$859.7K0.40%−28,268−34.5%Reduced
Wellington Management Group LLP54,402$870.4K0.00%−6,919−11.3%Reduced
Propel Bio Management, LLC59,085$945.4K0.81%+59,085New
Federated Hermes, Inc.62,636$1.00M0.00%+62,636New
Vivaldi Capital Management, LLC64,052$1.02M0.14%+12,300+23.8%Added
Susquehanna International Group, LLP67,722$1.08M0.00%+17,171+34.0%Added
Barclays PLC72,432$1.16M0.00%+24,606+51.4%Added
Algert Global LLC76,025$1.22M0.02%+76,025New
Ensign Peak Advisors, Inc77,275$1.24M0.00%00.0%Unchanged
Two Sigma Advisers, LP77,426$1.24M0.00%+69,729+905.9%Added
VARCOV Co.78,831$1.26M0.50%+78,831New
Citadel Advisors LLC80,574$1.29M0.00%−318,856−79.8%Reduced
XTX Topco Ltd85,782$1.37M0.04%+85,782New
Wealth Enhancement Advisory Services, LLC83,243$1.40M0.00%−122−0.1%Reduced
Nomura Asset Management Co Ltd96,780$1.55M0.00%+53,006+121.1%Added
Woodline Partners LP100,000$1.60M0.01%+100,000New
Dimensional Fund Advisors LP113,094$1.81M0.00%+72,208+176.6%Added
Bank of America Corp114,688$1.84M0.00%−234,440−67.2%Reduced
Scoggin Management LP125,000$2.00M0.74%−100,000−44.4%Reduced
Ameriprise Financial Inc136,896$2.19M0.00%+81,223+145.9%Added
AWM Investment Company, Inc.150,000$2.40M0.23%+150,000New
Blue Owl Capital Holdings LP150,000$2.40M0.74%+150,000New
Northern Trust Corp161,911$2.59M0.00%−3,368−2.0%Reduced
Charles Schwab Investment Management Inc169,122$2.71M0.00%+8,596+5.4%Added
Prelude Capital Management, LLC170,224$2.72M0.20%+170,224New
HRT Financial LP171,283$2.74M0.01%+141,974+484.4%Added
Trexquant Investment LP173,183$2.77M0.02%+173,183New
Silvercrest Asset Management Group LLC174,692$2.80M0.02%+174,692New
Sovran Advisors, LLC160,134$2.90M0.25%+53,214+49.8%Added
Skandinaviska Enskilda Banken AB (publ)185,642$2.97M0.01%00.0%Unchanged
Plustick Management LLC200,000$3.20M1.42%00.0%Unchanged
Morgan Stanley233,382$3.73M0.00%−62,837−21.2%Reduced
Discovery Capital Management, LLC241,300$3.86M0.21%+241,300New
Rock Springs Capital Management LP257,460$4.12M0.21%+21,233+9.0%Added
Goldman Sachs Group Inc257,942$4.13M0.00%+216,666+524.9%Added
Jacobs Levy Equity Management, Inc270,919$4.33M0.02%+270,919New
Vestal Point Capital, LP275,000$4.40M0.16%+275,000New
Two Sigma Investments, LP293,446$4.70M0.01%+233,264+387.6%Added
Primecap Management Co372,200$5.96M0.00%+372,200New
Candriam Luxembourg S.C.A.374,932$6.00M0.03%+145,990+63.8%Added
Nomura Asset Management International Inc.398,566$6.38M0.01%+398,566New
Granahan Investment Management Inc431,100$6.90M0.30%+239,703+125.2%Added
Geode Capital Management, LLC461,075$7.38M0.00%+6,179+1.4%Added
Alyeska Investment Group, L.P.463,495$7.42M0.02%+221,382+91.4%Added
Standard Life Aberdeen plc489,432$7.83M0.01%+358,706+274.4%Added
Squarepoint Ops LLC491,898$7.87M0.02%+402,110+447.8%Added
C WorldWide Group Holding A/S500,000$8.00M0.14%+500,000New
State Street Corp510,749$8.17M0.00%+92,765+22.2%Added
Millennium Management LLC539,348$8.63M0.01%+539,348New
Intrinsic Edge Capital Management LLC569,705$9.12M1.77%+569,705New
Tang Capital Management LLC865,169$13.8M0.68%−32,447−3.6%Reduced
72 Investment Holdings, LLC1,017,751$16.3M32.20%00.0%Unchanged
Price T Rowe Associates Inc1,023,542$16.4M0.00%+772,411+307.6%Added
Franklin Resources Inc1,096,334$17.5M0.00%+509,250+86.7%Added
Vanguard Group Inc1,321,202$21.1M0.00%−9,084−0.7%Reduced
UBS Group AG1,571,738$25.1M0.00%+370,122+30.8%Added
BlackRock, Inc.1,692,006$27.1M0.00%+218,902+14.9%Added
Versant Venture Management, LLC2,656,888$42.5M28.14%00.0%Unchanged
Falcon Edge Capital, LP3,612,211$57.8M7.08%00.0%Unchanged
FMR LLC3,702,718$59.2M0.00%+3,615,405+4,140.7%Added
Ra Capital Management, L.P.4,178,823$66.9M0.68%00.0%Unchanged
Paradigm Biocapital Advisors LP0$00.00%−1,073,461−100.0%Sold out
RTW Investments, LP0$00.00%−863,389−100.0%Sold out
First Light Asset Management, LLC0$00.00%−693,044−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−627,618−100.0%Sold out
Saturn V Capital Management LLC0$00.00%−368,176−100.0%Sold out
Samsara BioCapital, LLC0$00.00%−343,012−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−340,000−100.0%Sold out
Summit Partners Public Asset Management, LLC0$00.00%−323,857−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−175,363−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−114,612−100.0%Sold out
Tyro Capital Management LLC0$00.00%−100,672−100.0%Sold out
Lisanti Capital Growth, LLC0$00.00%−87,753−100.0%Sold out
Neuberger Berman Group LLC0$00.00%−84,011−100.0%Sold out
EAM Investors, LLC0$00.00%−80,187−100.0%Sold out
Calamos Advisors LLC0$00.00%−77,266−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−67,225−100.0%Sold out
CI Private Wealth, LLC0$00.00%−28,259−100.0%Sold out
Legato Capital Management LLC0$00.00%−21,870−100.0%Sold out
Cinctive Capital Management LP0$00.00%−21,062−100.0%Sold out
Principal Financial Group Inc0$00.00%−17,897−100.0%Sold out
Creative Planning0$00.00%−17,141−100.0%Sold out
Readystate Asset Management LP0$00.00%−14,701−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−11,619−100.0%Sold out
Commonwealth Equity Services, LLC0$00.00%−10,946−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−10,163−100.0%Sold out
SEI Investments Co0$00.00%−9,656−100.0%Sold out
Delta Investment Management, LLC0$00.00%−9,017−100.0%Sold out
Voleon Capital Management LP0$00.00%−8,591−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−8,500−100.0%Sold out
LPL Financial LLC0$00.00%−7,393−100.0%Sold out
Winton Group Ltd0$00.00%−7,131−100.0%Sold out
Advisory Services Network, LLC0$00.00%−6,421−100.0%Sold out
Intech Investment Management LLC0$00.00%−6,343−100.0%Sold out
Evoke Wealth, LLC0$00.00%−6,276−100.0%Sold out
Omers Administration Corp0$00.00%−5,800−100.0%Sold out
Radnor Capital Management, LLC0$00.00%−6,200−100.0%Sold out
Apollon Wealth Management, LLC0$00.00%−5,178−100.0%Sold out
Janus Henderson Group PLC0$00.00%−4,900−100.0%Sold out
Profund Advisors LLC0$00.00%−4,787−100.0%Sold out