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Kyverna Therapeutics, Inc.

KYTX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001994702

No open-market purchases or sales by Kyverna Therapeutics, Inc. insiders were filed in the last 90 days; 120 institutions reported holding it in 13F filings for Q2 2026, worth $335.1M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Kyverna Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
99
+27 vs. Q3 2025
Shares held
34.1M
+16.0M (+88.1%) vs. Q3 2025
Total value
$320.8M
+$212.0M (+194.8%) vs. Q3 2025
New holders
36
29 more added
Sold out
9
21 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KYTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 99 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 90 institutionsQ2 2024: 88 institutionsQ3 2024: 94 institutionsQ4 2024: 88 institutionsQ1 2025: 87 institutionsQ2 2025: 79 institutionsQ3 2025: 75 institutionsQ4 2025: 99 institutionsQ1 2026: 111 institutionsQ2 2026: 120 institutions
Value heldQ4 2025: $320.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $762.3MQ2 2024: $239.7MQ3 2024: $138.3MQ4 2024: $108.0MQ1 2025: $49.8MQ2 2025: $71.2MQ3 2025: $136.1MQ4 2025: $320.8MQ1 2026: $300.5MQ2 2026: $335.1M
Institutions holding KYTX and their total value by quarter
QuarterHoldersValue
Q2 2026120$335.1M
Q1 2026111$300.5M
Q4 202599$320.8M
Q3 202575$136.1M
Q2 202579$71.2M
Q1 202587$49.8M
Q4 202488$108.0M
Q3 202494$138.3M
Q2 202488$239.7M
Q1 202490$762.3M
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Kyverna Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding KYTX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GordonMD Global Investments LP4,391,818$41.3M29.60%+4,391,818New
Gilead Sciences, Inc.4,126,119$38.8M2.00%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC3,110,000$29.2M2.24%−258,370−7.7%Reduced
Deerfield Management Company, L.P. (Series C)2,000,000$18.8M0.24%+2,000,000New
Vanguard Group Inc1,781,257$16.7M0.00%+458,632+34.7%Added
Price T Rowe Associates Inc1,762,617$16.6M0.00%+250,418+16.6%Added
Adage Capital Partners GP, L.L.C.1,666,666$15.7M0.02%+1,666,666New
AIGH Capital Management LLC1,500,000$14.1M4.17%+1,500,000New
Morgan Stanley1,002,495$9.42M0.00%+828,292+475.5%Added
Insight Holdings Group, LLC989,054$9.30M0.70%00.0%Unchanged
Balyasny Asset Management LLC980,869$9.22M0.02%+980,869New
Woodline Partners LP845,143$7.94M0.03%+592,931+235.1%Added
Propel Bio Management, LLC666,666$6.27M5.35%+666,666New
MBB Public Markets I LLC614,477$5.78M0.60%00.0%Unchanged
Alyeska Investment Group, L.P.600,000$5.64M0.02%+600,000New
Millennium Management LLC593,369$5.58M0.00%+41,734+7.6%Added
BlackRock, Inc.544,539$5.12M0.00%+62,485+13.0%Added
D. E. Shaw & Co., Inc.518,512$4.87M0.00%+518,512New
RFG Advisory, LLC445,200$4.18M0.08%+445,200New
Citadel Advisors LLC275,446$2.59M0.00%+257,780+1,459.2%Added
Heights Capital Management, Inc271,822$2.56M0.97%+271,822New
Geode Capital Management, LLC266,402$2.51M0.00%−11,927−4.3%Reduced
BNP Paribas Arbitrage, SA252,151$2.37M0.00%+218,129+641.1%Added
Susquehanna International Group, LLP238,828$2.24M0.00%+36,138+17.8%Added
TD Asset Management Inc222,796$2.09M0.00%+58,000+35.2%Added
Two Sigma Investments, LP205,267$1.93M0.00%+72,816+55.0%Added
UBS Group AG202,187$1.90M0.00%+44,765+28.4%Added
Burkehill Global Management, LP200,000$1.88M0.12%+200,000New
Monashee Investment Management LLC195,000$1.83M1.03%+195,000New
Simplify Asset Management Inc.192,339$1.81M0.03%+192,339New
Peapod Lane Capital LLC183,820$1.73M1.47%−134,940−42.3%Reduced
Jane Street Group, LLC182,093$1.71M0.00%−16,758−8.4%Reduced
Renaissance Technologies LLC177,899$1.67M0.00%+13,285+8.1%Added
Bridgeway Capital Management, LLC174,900$1.64M0.03%00.0%Unchanged
Barclays PLC164,668$1.55M0.00%+88,477+116.1%Added
Maven Securities LTD146,400$1.38M0.17%+146,400New
Squarepoint Ops LLC138,868$1.31M0.00%+138,868New
Marshall Wace, LLP135,600$1.27M0.00%+135,600New
Manufacturers Life Insurance Company, The134,530$1.26M0.00%+30,722+29.6%Added
Goldman Sachs Group Inc133,530$1.26M0.00%+90,398+209.6%Added
Stifel Financial Corp125,790$1.18M0.00%+86,969+224.0%Added
Charles Schwab Investment Management Inc125,426$1.18M0.00%−152−0.1%Reduced
683 Capital Management, LLC114,900$1.08M0.09%+114,900New
Kera Capital Partners, Inc.132,603$1.06M0.13%−289,321−68.6%Reduced
Jacobs Levy Equity Management, Inc108,534$1.02M0.00%−39,178−26.5%Reduced
State Street Corp91,300$858.2K0.00%00.0%Unchanged
Hudson Bay Capital Management LP88,553$832.4K0.00%+88,553New
Jump Financial, LLC80,299$754.8K0.01%+80,299New
Dimensional Fund Advisors LP78,413$737.1K0.00%+78,413New
Wells Fargo & Company74,949$704.5K0.00%+56,669+310.0%Added
Voya Investment Management LLC68,140$640.5K0.00%+68,140New
Qube Research & Technologies Ltd63,616$598.0K0.00%+26,925+73.4%Added
ADAR1 Capital Management, LLC57,428$539.8K0.04%+57,428New
Quadrature Capital Ltd57,369$539.3K0.01%+57,369New
Nano Cap New Millennium Growth Fund L P53,500$502.9K0.43%+53,500New
Northern Trust Corp51,572$484.8K0.00%−106−0.2%Reduced
Two Sigma Advisers, LP49,400$464.4K0.00%−31,900−39.2%Reduced
American Century Companies Inc46,367$435.9K0.00%+14,162+44.0%Added
Omers Administration Corp34,800$327.1K0.00%+34,800New
Point72 Asset Management, L.P.32,184$302.5K0.00%+5,008+18.4%Added
Jefferies Financial Group Inc.32,001$300.8K0.00%+15,701+96.3%Added
Schonfeld Strategic Advisors LLC28,872$271.4K0.00%+28,872New
Bank of America Corp28,709$269.9K0.00%−36,255−55.8%Reduced
ACT Capital Management, LLC25,100$235.9K0.19%+25,100New
Raymond James Financial Inc25,082$235.8K0.00%+25,082New
XTX Topco Ltd23,282$218.9K0.01%−25,825−52.6%Reduced
DekaBank Deutsche Girozentrale7,500$197.0K0.00%00.0%Unchanged
Federated Hermes, Inc.20,705$194.6K0.00%+5,547+36.6%Added
JustInvest LLC19,048$179.1K0.00%+155+0.8%Added
Caxton Corp18,773$176.5K4.12%−4,208−18.3%Reduced
Cambria Investment Management, L.P.17,935$168.6K0.01%+17,935New
Quest Partners LLC16,343$153.6K0.01%+16,343New
Ethic Inc.12,609$118.5K0.00%−2,744−17.9%Reduced
Phoenix Wealth Advisors12,300$115.6K0.04%+1,800+17.1%Added
Citigroup Inc12,297$115.6K0.00%+8,978+270.5%Added
EntryPoint Capital, LLC10,048$94.5K0.04%+10,048New
Capital Advisors Inc10,000$94.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.7,137$67.1K0.01%−443−5.8%Reduced
FMR LLC6,976$65.6K0.00%−942−11.9%Reduced
Tower Research Capital LLC (TRC)5,073$47.7K0.00%−1,158−18.6%Reduced
JPMorgan Chase & Co4,274$40.2K0.00%−2,401−36.0%Reduced
Deutsche Bank AG3,917$36.8K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.3,225$30.3K0.00%+725+29.0%Added
Royal Bank of Canada3,264$30.0K0.00%+1,243+61.5%Added
Mirae Asset Global Investments Co., Ltd.2,128$20.0K0.00%+456+27.3%Added
The PNC Financial Services Group, Inc.1,668$15.7K0.00%00.0%Unchanged
Russell Investments Group, Ltd.1,313$12.3K0.00%00.0%Unchanged
Vermillion & White Wealth Management Group, LLC1,100$10.3K0.01%+1,100New
GF Fund Management Co. Ltd.860$8.08K0.00%−38−4.2%Reduced
National Bank of Canada400$3.76K0.00%+400New
Nisa Investment Advisors, LLC301$2.83K0.00%00.0%Unchanged
TFC Financial Management300$2.82K0.00%+300New
Fourth Dimension Wealth, LLC250$2.35K0.00%00.0%Unchanged
CWM, LLC263$2.00K0.00%−236−47.3%Reduced
EverSource Wealth Advisors, LLC163$1.53K0.00%−37−18.5%Reduced
Jones Financial Companies LLLP37$3480.00%+37New
Parallel Advisors, LLC26$2440.00%+26New
SBI Securities Co., Ltd.22$2070.00%−115−83.9%Reduced
SRS Capital Advisors, Inc.11$1030.00%00.0%Unchanged
Franklin Resources Inc0$00.00%−677,587−100.0%Sold out