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Kyverna Therapeutics, Inc.

KYTX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001994702

No open-market purchases or sales by Kyverna Therapeutics, Inc. insiders were filed in the last 90 days; 120 institutions reported holding it in 13F filings for Q2 2026, worth $335.1M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Kyverna Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
99
+27 vs. Q3 2025
Shares held
34.1M
+16.0M (+88.1%) vs. Q3 2025
Total value
$320.8M
+$212.0M (+194.8%) vs. Q3 2025
New holders
36
29 more added
Sold out
9
21 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KYTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 99 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 90 institutionsQ2 2024: 88 institutionsQ3 2024: 94 institutionsQ4 2024: 88 institutionsQ1 2025: 87 institutionsQ2 2025: 79 institutionsQ3 2025: 75 institutionsQ4 2025: 99 institutionsQ1 2026: 111 institutionsQ2 2026: 120 institutions
Value heldQ4 2025: $320.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $762.3MQ2 2024: $239.7MQ3 2024: $138.3MQ4 2024: $108.0MQ1 2025: $49.8MQ2 2025: $71.2MQ3 2025: $136.1MQ4 2025: $320.8MQ1 2026: $300.5MQ2 2026: $335.1M
Institutions holding KYTX and their total value by quarter
QuarterHoldersValue
Q2 2026120$335.1M
Q1 2026111$300.5M
Q4 202599$320.8M
Q3 202575$136.1M
Q2 202579$71.2M
Q1 202587$49.8M
Q4 202488$108.0M
Q3 202494$138.3M
Q2 202488$239.7M
Q1 202490$762.3M
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Kyverna Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding KYTX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
SRS Capital Advisors, Inc.11$1030.00%00.0%Unchanged
SBI Securities Co., Ltd.22$2070.00%−115−83.9%Reduced
Parallel Advisors, LLC26$2440.00%+26New
Jones Financial Companies LLLP37$3480.00%+37New
EverSource Wealth Advisors, LLC163$1.53K0.00%−37−18.5%Reduced
CWM, LLC263$2.00K0.00%−236−47.3%Reduced
Fourth Dimension Wealth, LLC250$2.35K0.00%00.0%Unchanged
TFC Financial Management300$2.82K0.00%+300New
Nisa Investment Advisors, LLC301$2.83K0.00%00.0%Unchanged
National Bank of Canada400$3.76K0.00%+400New
GF Fund Management Co. Ltd.860$8.08K0.00%−38−4.2%Reduced
Vermillion & White Wealth Management Group, LLC1,100$10.3K0.01%+1,100New
Russell Investments Group, Ltd.1,313$12.3K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.1,668$15.7K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,128$20.0K0.00%+456+27.3%Added
Royal Bank of Canada3,264$30.0K0.00%+1,243+61.5%Added
Advisor Group Holdings, Inc.3,225$30.3K0.00%+725+29.0%Added
Deutsche Bank AG3,917$36.8K0.00%00.0%Unchanged
JPMorgan Chase & Co4,274$40.2K0.00%−2,401−36.0%Reduced
Tower Research Capital LLC (TRC)5,073$47.7K0.00%−1,158−18.6%Reduced
FMR LLC6,976$65.6K0.00%−942−11.9%Reduced
China Universal Asset Management Co., Ltd.7,137$67.1K0.01%−443−5.8%Reduced
Capital Advisors Inc10,000$94.0K0.00%00.0%Unchanged
EntryPoint Capital, LLC10,048$94.5K0.04%+10,048New
Citigroup Inc12,297$115.6K0.00%+8,978+270.5%Added
Phoenix Wealth Advisors12,300$115.6K0.04%+1,800+17.1%Added
Ethic Inc.12,609$118.5K0.00%−2,744−17.9%Reduced
Quest Partners LLC16,343$153.6K0.01%+16,343New
Cambria Investment Management, L.P.17,935$168.6K0.01%+17,935New
Caxton Corp18,773$176.5K4.12%−4,208−18.3%Reduced
JustInvest LLC19,048$179.1K0.00%+155+0.8%Added
Federated Hermes, Inc.20,705$194.6K0.00%+5,547+36.6%Added
DekaBank Deutsche Girozentrale7,500$197.0K0.00%00.0%Unchanged
XTX Topco Ltd23,282$218.9K0.01%−25,825−52.6%Reduced
Raymond James Financial Inc25,082$235.8K0.00%+25,082New
ACT Capital Management, LLC25,100$235.9K0.19%+25,100New
Bank of America Corp28,709$269.9K0.00%−36,255−55.8%Reduced
Schonfeld Strategic Advisors LLC28,872$271.4K0.00%+28,872New
Jefferies Financial Group Inc.32,001$300.8K0.00%+15,701+96.3%Added
Point72 Asset Management, L.P.32,184$302.5K0.00%+5,008+18.4%Added
Omers Administration Corp34,800$327.1K0.00%+34,800New
American Century Companies Inc46,367$435.9K0.00%+14,162+44.0%Added
Two Sigma Advisers, LP49,400$464.4K0.00%−31,900−39.2%Reduced
Northern Trust Corp51,572$484.8K0.00%−106−0.2%Reduced
Nano Cap New Millennium Growth Fund L P53,500$502.9K0.43%+53,500New
Quadrature Capital Ltd57,369$539.3K0.01%+57,369New
ADAR1 Capital Management, LLC57,428$539.8K0.04%+57,428New
Qube Research & Technologies Ltd63,616$598.0K0.00%+26,925+73.4%Added
Voya Investment Management LLC68,140$640.5K0.00%+68,140New
Wells Fargo & Company74,949$704.5K0.00%+56,669+310.0%Added
Dimensional Fund Advisors LP78,413$737.1K0.00%+78,413New
Jump Financial, LLC80,299$754.8K0.01%+80,299New
Hudson Bay Capital Management LP88,553$832.4K0.00%+88,553New
State Street Corp91,300$858.2K0.00%00.0%Unchanged
Jacobs Levy Equity Management, Inc108,534$1.02M0.00%−39,178−26.5%Reduced
Kera Capital Partners, Inc.132,603$1.06M0.13%−289,321−68.6%Reduced
683 Capital Management, LLC114,900$1.08M0.09%+114,900New
Charles Schwab Investment Management Inc125,426$1.18M0.00%−152−0.1%Reduced
Stifel Financial Corp125,790$1.18M0.00%+86,969+224.0%Added
Goldman Sachs Group Inc133,530$1.26M0.00%+90,398+209.6%Added
Manufacturers Life Insurance Company, The134,530$1.26M0.00%+30,722+29.6%Added
Marshall Wace, LLP135,600$1.27M0.00%+135,600New
Squarepoint Ops LLC138,868$1.31M0.00%+138,868New
Maven Securities LTD146,400$1.38M0.17%+146,400New
Barclays PLC164,668$1.55M0.00%+88,477+116.1%Added
Bridgeway Capital Management, LLC174,900$1.64M0.03%00.0%Unchanged
Renaissance Technologies LLC177,899$1.67M0.00%+13,285+8.1%Added
Jane Street Group, LLC182,093$1.71M0.00%−16,758−8.4%Reduced
Peapod Lane Capital LLC183,820$1.73M1.47%−134,940−42.3%Reduced
Simplify Asset Management Inc.192,339$1.81M0.03%+192,339New
Monashee Investment Management LLC195,000$1.83M1.03%+195,000New
Burkehill Global Management, LP200,000$1.88M0.12%+200,000New
UBS Group AG202,187$1.90M0.00%+44,765+28.4%Added
Two Sigma Investments, LP205,267$1.93M0.00%+72,816+55.0%Added
TD Asset Management Inc222,796$2.09M0.00%+58,000+35.2%Added
Susquehanna International Group, LLP238,828$2.24M0.00%+36,138+17.8%Added
BNP Paribas Arbitrage, SA252,151$2.37M0.00%+218,129+641.1%Added
Geode Capital Management, LLC266,402$2.51M0.00%−11,927−4.3%Reduced
Heights Capital Management, Inc271,822$2.56M0.97%+271,822New
Citadel Advisors LLC275,446$2.59M0.00%+257,780+1,459.2%Added
RFG Advisory, LLC445,200$4.18M0.08%+445,200New
D. E. Shaw & Co., Inc.518,512$4.87M0.00%+518,512New
BlackRock, Inc.544,539$5.12M0.00%+62,485+13.0%Added
Millennium Management LLC593,369$5.58M0.00%+41,734+7.6%Added
Alyeska Investment Group, L.P.600,000$5.64M0.02%+600,000New
MBB Public Markets I LLC614,477$5.78M0.60%00.0%Unchanged
Propel Bio Management, LLC666,666$6.27M5.35%+666,666New
Woodline Partners LP845,143$7.94M0.03%+592,931+235.1%Added
Balyasny Asset Management LLC980,869$9.22M0.02%+980,869New
Insight Holdings Group, LLC989,054$9.30M0.70%00.0%Unchanged
Morgan Stanley1,002,495$9.42M0.00%+828,292+475.5%Added
AIGH Capital Management LLC1,500,000$14.1M4.17%+1,500,000New
Adage Capital Partners GP, L.L.C.1,666,666$15.7M0.02%+1,666,666New
Price T Rowe Associates Inc1,762,617$16.6M0.00%+250,418+16.6%Added
Vanguard Group Inc1,781,257$16.7M0.00%+458,632+34.7%Added
Deerfield Management Company, L.P. (Series C)2,000,000$18.8M0.24%+2,000,000New
Bain Capital Life Sciences Investors, LLC3,110,000$29.2M2.24%−258,370−7.7%Reduced
Gilead Sciences, Inc.4,126,119$38.8M2.00%00.0%Unchanged
GordonMD Global Investments LP4,391,818$41.3M29.60%+4,391,818New
Franklin Resources Inc0$00.00%−677,587−100.0%Sold out