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Kymera Therapeutics, Inc.

KYMR
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001815442

In the last 90 days, Kymera Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 276 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Kymera Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
255
+53 vs. Q3 2025
Shares held
89.9M
+9.15M (+11.3%) vs. Q3 2025
Total value
$6.99B
+$2.42B (+53.1%) vs. Q3 2025
New holders
68
98 more added
Sold out
15
64 more reduced

8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KYMR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 255 institutions
Q1 2021: 97 institutionsQ2 2021: 110 institutionsQ3 2021: 115 institutionsQ4 2021: 128 institutionsQ1 2022: 126 institutionsQ2 2022: 101 institutionsQ3 2022: 128 institutionsQ4 2022: 121 institutionsQ1 2023: 127 institutionsQ2 2023: 129 institutionsQ3 2023: 122 institutionsQ4 2023: 137 institutionsQ1 2024: 164 institutionsQ2 2024: 157 institutionsQ3 2024: 176 institutionsQ4 2024: 181 institutionsQ1 2025: 174 institutionsQ2 2025: 210 institutionsQ3 2025: 210 institutionsQ4 2025: 255 institutionsQ1 2026: 256 institutionsQ2 2026: 276 institutions
Value heldQ4 2025: $6.99B
Q1 2021: $887.2MQ2 2021: $1.29BQ3 2021: $2.04BQ4 2021: $2.76BQ1 2022: $1.93BQ2 2022: $973.6MQ3 2022: $1.15BQ4 2022: $1.40BQ1 2023: $1.68BQ2 2023: $1.34BQ3 2023: $797.2MQ4 2023: $1.54BQ1 2024: $2.70BQ2 2024: $2.01BQ3 2024: $3.27BQ4 2024: $2.89BQ1 2025: $2.00BQ2 2025: $3.44BQ3 2025: $4.58BQ4 2025: $6.99BQ1 2026: $8.01BQ2 2026: $11.1B
Institutions holding KYMR and their total value by quarter
QuarterHoldersValue
Q2 2026276$11.1B
Q1 2026256$8.01B
Q4 2025255$6.99B
Q3 2025210$4.58B
Q2 2025210$3.44B
Q1 2025174$2.00B
Q4 2024181$2.89B
Q3 2024176$3.27B
Q2 2024157$2.01B
Q1 2024164$2.70B
Q4 2023137$1.54B
Q3 2023122$797.2M
Q2 2023129$1.34B
Q1 2023127$1.68B
Q4 2022121$1.40B
Q3 2022128$1.15B
Q2 2022101$973.6M
Q1 2022126$1.93B
Q4 2021128$2.76B
Q3 2021115$2.04B
Q2 2021110$1.29B
Q1 202197$887.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Kymera Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding KYMR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Point72 Asset Management, L.P.173,147$13.5M0.02%−753−0.4%Reduced
TimesSquare Capital Management, LLC189,900$14.8M0.22%+189,900New
Bank of New York Mellon Corp192,748$15.0M0.00%+40,296+26.4%Added
Polar Capital Holdings Plc200,946$15.6M0.07%−196,095−49.4%Reduced
Candriam Luxembourg S.C.A.201,672$15.7M0.08%+10,033+5.2%Added
Woodline Partners LP203,585$15.8M0.06%−44,415−17.9%Reduced
First Turn Management, LLC206,445$16.1M1.84%−71,281−25.7%Reduced
TD Asset Management Inc221,178$17.2M0.01%+11,930+5.7%Added
Deer Management Co. LLC230,811$18.0M1.75%−95,084−29.2%Reduced
Gilder Gagnon Howe & Co LLC239,916$18.7M0.20%−6,788−2.8%Reduced
RTW Investments, LP240,000$18.7M0.19%+240,000New
Two Sigma Investments, LP265,532$20.7M0.03%−164,443−38.2%Reduced
Morgan Stanley274,018$21.3M0.00%−103,781−27.5%Reduced
Nextech Invest, Ltd.278,896$21.7M2.10%−62,013−18.2%Reduced
Massachusetts Financial Services Co289,404$22.5M0.01%−145,610−33.5%Reduced
Boxer Capital Management, LLC329,100$25.6M5.60%+10,000+3.1%Added
Bank of America Corp338,999$26.4M0.00%+152,745+82.0%Added
Franklin Resources Inc354,575$27.6M0.01%+322,913+1,019.9%Added
Alyeska Investment Group, L.P.371,889$28.9M0.08%−243,202−39.5%Reduced
Two Sigma Advisers, LP373,800$29.1M0.06%+1,400+0.4%Added
Adage Capital Partners GP, L.L.C.430,000$33.5M0.05%+192,000+80.7%Added
Braidwell LP454,259$35.3M1.13%+177,567+64.2%Added
Northern Trust Corp467,022$36.3M0.00%+29,902+6.8%Added
Pictet Asset Management Holding SA483,199$37.8M0.04%+136,382+39.3%Added
Jennison Associates LLC496,665$38.6M0.02%−531,074−51.7%Reduced
Rock Springs Capital Management LP496,871$38.7M1.98%+46,497+10.3%Added
Charles Schwab Investment Management Inc497,026$38.7M0.01%+57,201+13.0%Added
Octagon Capital Advisors LP535,000$41.6M5.21%+175,000+48.6%Added
Deerfield Management Company, L.P. (Series C)561,170$43.7M0.56%−11,088−1.9%Reduced
Dimensional Fund Advisors LP624,027$48.6M0.01%−107,393−14.7%Reduced
Eventide Asset Management, LLC626,430$48.7M0.76%−18,160−2.8%Reduced
T. Rowe Price Investment Management, Inc.629,745$49.0M0.03%+18,524+3.0%Added
Frontier Capital Management Co LLC635,957$49.5M0.53%+117,900+22.8%Added
UBS Group AG737,032$57.3M0.01%+88,314+13.6%Added
Goldman Sachs Group Inc740,306$57.6M0.01%+28,862+4.1%Added
Commodore Capital LP750,000$58.4M3.88%00.0%Unchanged
Holocene Advisors, LP761,209$59.2M0.12%−79,124−9.4%Reduced
Federated Hermes, Inc.763,920$59.4M0.10%+205,220+36.7%Added
Merck & Co., Inc.772,165$60.1M21.75%00.0%Unchanged
UBS Asset Management Americas Inc912,498$71.0M0.02%+48,736+5.6%Added
Alliancebernstein L.P.952,065$74.1M0.02%+903,296+1,852.2%Added
Driehaus Capital Management LLC1,069,238$83.2M0.57%+130,144+13.9%Added
Geode Capital Management, LLC1,417,389$110.3M0.01%+140,623+11.0%Added
Capital Research Global Investors1,560,791$121.4M0.02%+298,609+23.7%Added
State Street Corp2,209,837$171.9M0.01%+190,383+9.4%Added
Siren, L.L.C.3,286,830$255.7M7.63%−141,320−4.1%Reduced
Wellington Management Group LLP4,412,933$343.4M0.06%−782,758−15.1%Reduced
Atlas Venture Life Science Advisors, LLC4,659,874$362.6M41.91%−236,588−4.8%Reduced
BlackRock, Inc.5,004,095$389.4M0.01%+638,647+14.6%Added
BVF Inc5,502,710$428.2M14.41%00.0%Unchanged
Price T Rowe Associates Inc6,159,335$479.3M0.05%+1,061,957+20.8%Added
Vanguard Group Inc6,267,644$487.7M0.01%+845,922+15.6%Added
Avoro Capital Advisors LLC7,474,747$581.6M5.72%+1,124,747+17.7%Added
Baker Bros. Advisors LP8,657,242$673.6M3.94%+2,005,813+30.2%Added
FMR LLC8,928,574$694.7M0.04%+3,048,963+51.9%Added
Atika Capital Management LLC0$00.00%−81,300−100.0%Sold out
Checkpoint Capital L.P.0$00.00%−61,750−100.0%Sold out
Jain Global LLC0$00.00%−58,480−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−39,746−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−23,134−100.0%Sold out
Neo Ivy Capital Management0$00.00%−19,660−100.0%Sold out
Westwood Holdings Group Inc.0$00.00%−10,926−100.0%Sold out
Engineers Gate Manager LP0$00.00%−6,475−100.0%Sold out
Altfest L J & Co Inc0$00.00%−5,318−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−5,137−100.0%Sold out
Advisory Services Network, LLC0$00.00%−13−100.0%Sold out
Montag A & Associates Inc0$00.00%−6−100.0%Sold out
Principal Securities, Inc.0$00.00%−5−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−5−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−2−100.0%Sold out
AXA Investment Managers S.A.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Bryce Point Capital, LLC––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Glenmede Investment Management, LP––––Not filed
Shell Asset Management Co––––Not filed
Point72 Europe (London) LLP––––Not filed
Hemington Wealth Management––––Not filed