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Kymera Therapeutics, Inc.

KYMR
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001815442

In the last 90 days, Kymera Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 276 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Kymera Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
255
+53 vs. Q3 2025
Shares held
89.9M
+9.15M (+11.3%) vs. Q3 2025
Total value
$6.99B
+$2.42B (+53.1%) vs. Q3 2025
New holders
68
98 more added
Sold out
15
64 more reduced

8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KYMR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 255 institutions
Q1 2021: 97 institutionsQ2 2021: 110 institutionsQ3 2021: 115 institutionsQ4 2021: 128 institutionsQ1 2022: 126 institutionsQ2 2022: 101 institutionsQ3 2022: 128 institutionsQ4 2022: 121 institutionsQ1 2023: 127 institutionsQ2 2023: 129 institutionsQ3 2023: 122 institutionsQ4 2023: 137 institutionsQ1 2024: 164 institutionsQ2 2024: 157 institutionsQ3 2024: 176 institutionsQ4 2024: 181 institutionsQ1 2025: 174 institutionsQ2 2025: 210 institutionsQ3 2025: 210 institutionsQ4 2025: 255 institutionsQ1 2026: 256 institutionsQ2 2026: 276 institutions
Value heldQ4 2025: $6.99B
Q1 2021: $887.2MQ2 2021: $1.29BQ3 2021: $2.04BQ4 2021: $2.76BQ1 2022: $1.93BQ2 2022: $973.6MQ3 2022: $1.15BQ4 2022: $1.40BQ1 2023: $1.68BQ2 2023: $1.34BQ3 2023: $797.2MQ4 2023: $1.54BQ1 2024: $2.70BQ2 2024: $2.01BQ3 2024: $3.27BQ4 2024: $2.89BQ1 2025: $2.00BQ2 2025: $3.44BQ3 2025: $4.58BQ4 2025: $6.99BQ1 2026: $8.01BQ2 2026: $11.1B
Institutions holding KYMR and their total value by quarter
QuarterHoldersValue
Q2 2026276$11.1B
Q1 2026256$8.01B
Q4 2025255$6.99B
Q3 2025210$4.58B
Q2 2025210$3.44B
Q1 2025174$2.00B
Q4 2024181$2.89B
Q3 2024176$3.27B
Q2 2024157$2.01B
Q1 2024164$2.70B
Q4 2023137$1.54B
Q3 2023122$797.2M
Q2 2023129$1.34B
Q1 2023127$1.68B
Q4 2022121$1.40B
Q3 2022128$1.15B
Q2 2022101$973.6M
Q1 2022126$1.93B
Q4 2021128$2.76B
Q3 2021115$2.04B
Q2 2021110$1.29B
Q1 202197$887.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Kymera Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding KYMR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC8,928,574$694.7M0.04%+3,048,963+51.9%Added
Baker Bros. Advisors LP8,657,242$673.6M3.94%+2,005,813+30.2%Added
Avoro Capital Advisors LLC7,474,747$581.6M5.72%+1,124,747+17.7%Added
Vanguard Group Inc6,267,644$487.7M0.01%+845,922+15.6%Added
Price T Rowe Associates Inc6,159,335$479.3M0.05%+1,061,957+20.8%Added
BVF Inc5,502,710$428.2M14.41%00.0%Unchanged
BlackRock, Inc.5,004,095$389.4M0.01%+638,647+14.6%Added
Atlas Venture Life Science Advisors, LLC4,659,874$362.6M41.91%−236,588−4.8%Reduced
Wellington Management Group LLP4,412,933$343.4M0.06%−782,758−15.1%Reduced
Siren, L.L.C.3,286,830$255.7M7.63%−141,320−4.1%Reduced
State Street Corp2,209,837$171.9M0.01%+190,383+9.4%Added
Capital Research Global Investors1,560,791$121.4M0.02%+298,609+23.7%Added
Geode Capital Management, LLC1,417,389$110.3M0.01%+140,623+11.0%Added
Driehaus Capital Management LLC1,069,238$83.2M0.57%+130,144+13.9%Added
Alliancebernstein L.P.952,065$74.1M0.02%+903,296+1,852.2%Added
UBS Asset Management Americas Inc912,498$71.0M0.02%+48,736+5.6%Added
Merck & Co., Inc.772,165$60.1M21.75%00.0%Unchanged
Federated Hermes, Inc.763,920$59.4M0.10%+205,220+36.7%Added
Holocene Advisors, LP761,209$59.2M0.12%−79,124−9.4%Reduced
Commodore Capital LP750,000$58.4M3.88%00.0%Unchanged
Goldman Sachs Group Inc740,306$57.6M0.01%+28,862+4.1%Added
UBS Group AG737,032$57.3M0.01%+88,314+13.6%Added
Frontier Capital Management Co LLC635,957$49.5M0.53%+117,900+22.8%Added
T. Rowe Price Investment Management, Inc.629,745$49.0M0.03%+18,524+3.0%Added
Eventide Asset Management, LLC626,430$48.7M0.76%−18,160−2.8%Reduced
Dimensional Fund Advisors LP624,027$48.6M0.01%−107,393−14.7%Reduced
Deerfield Management Company, L.P. (Series C)561,170$43.7M0.56%−11,088−1.9%Reduced
Octagon Capital Advisors LP535,000$41.6M5.21%+175,000+48.6%Added
Charles Schwab Investment Management Inc497,026$38.7M0.01%+57,201+13.0%Added
Rock Springs Capital Management LP496,871$38.7M1.98%+46,497+10.3%Added
Jennison Associates LLC496,665$38.6M0.02%−531,074−51.7%Reduced
Pictet Asset Management Holding SA483,199$37.8M0.04%+136,382+39.3%Added
Northern Trust Corp467,022$36.3M0.00%+29,902+6.8%Added
Braidwell LP454,259$35.3M1.13%+177,567+64.2%Added
Adage Capital Partners GP, L.L.C.430,000$33.5M0.05%+192,000+80.7%Added
Two Sigma Advisers, LP373,800$29.1M0.06%+1,400+0.4%Added
Alyeska Investment Group, L.P.371,889$28.9M0.08%−243,202−39.5%Reduced
Franklin Resources Inc354,575$27.6M0.01%+322,913+1,019.9%Added
Bank of America Corp338,999$26.4M0.00%+152,745+82.0%Added
Boxer Capital Management, LLC329,100$25.6M5.60%+10,000+3.1%Added
Massachusetts Financial Services Co289,404$22.5M0.01%−145,610−33.5%Reduced
Nextech Invest, Ltd.278,896$21.7M2.10%−62,013−18.2%Reduced
Morgan Stanley274,018$21.3M0.00%−103,781−27.5%Reduced
Two Sigma Investments, LP265,532$20.7M0.03%−164,443−38.2%Reduced
RTW Investments, LP240,000$18.7M0.19%+240,000New
Gilder Gagnon Howe & Co LLC239,916$18.7M0.20%−6,788−2.8%Reduced
Deer Management Co. LLC230,811$18.0M1.75%−95,084−29.2%Reduced
TD Asset Management Inc221,178$17.2M0.01%+11,930+5.7%Added
First Turn Management, LLC206,445$16.1M1.84%−71,281−25.7%Reduced
Woodline Partners LP203,585$15.8M0.06%−44,415−17.9%Reduced
Candriam Luxembourg S.C.A.201,672$15.7M0.08%+10,033+5.2%Added
Polar Capital Holdings Plc200,946$15.6M0.07%−196,095−49.4%Reduced
Bank of New York Mellon Corp192,748$15.0M0.00%+40,296+26.4%Added
TimesSquare Capital Management, LLC189,900$14.8M0.22%+189,900New
Point72 Asset Management, L.P.173,147$13.5M0.02%−753−0.4%Reduced
Citadel Advisors LLC159,865$12.4M0.01%+118,042+282.2%Added
Squarepoint Ops LLC159,426$12.4M0.03%−191,820−54.6%Reduced
Foresite Capital Management VI LLC146,332$11.4M3.44%00.0%Unchanged
Barclays PLC140,507$10.9M0.00%−14,637−9.4%Reduced
Patient Square Capital LP139,000$10.8M2.32%+46,408+50.1%Added
Manufacturers Life Insurance Company, The135,894$10.6M0.01%+9,404+7.4%Added
Eagle Health Investments LP136,300$10.6M2.33%+136,300New
JPMorgan Chase & Co131,353$10.2M0.00%−61,346−31.8%Reduced
Logos Global Management LP130,000$10.1M0.67%−120,000−48.0%Reduced
Nuveen, LLC125,050$9.73M0.00%+18,345+17.2%Added
Invesco Ltd.116,747$9.08M0.00%+36,940+46.3%Added
WCM Investment Management, LLC105,194$8.22M0.02%+105,194New
Universal- Beteiligungs- und Servicegesellschaft mbH105,554$8.21M0.01%−2,149−2.0%Reduced
Monashee Investment Management LLC100,000$7.78M4.38%+100,000New
Ensign Peak Advisors, Inc95,047$7.40M0.01%+3,150+3.4%Added
Swiss National Bank94,200$7.33M0.00%+12,600+15.4%Added
Armistice Capital, LLC81,165$6.32M0.15%+81,165New
Deutsche Bank AG79,843$6.21M0.00%+7,106+9.8%Added
Burkehill Global Management, LP75,000$5.84M0.38%00.0%Unchanged
Yiheng Capital Management, L.P.73,440$5.71M2.49%−49,165−40.1%Reduced
Rhumbline Advisers72,304$5.63M0.00%−1,869−2.5%Reduced
Perceptive Advisors LLC69,935$5.44M0.10%−99,861−58.8%Reduced
Victory Capital Management Inc67,086$5.22M0.00%+35,797+114.4%Added
Wells Fargo & Company66,489$5.17M0.00%+34,428+107.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.64,775$5.04M0.01%+64,363+15,622.1%Added
Alps Advisors Inc64,723$5.04M0.03%+64,723New
First Trust Advisors LP58,862$4.58M0.00%−15,990−21.4%Reduced
Rafferty Asset Management, LLC58,653$4.56M0.02%−9,642−14.1%Reduced
Neuberger Berman Group LLC58,482$4.55M0.00%+58,482New
EAM Investors, LLC56,455$4.39M0.49%−1,130−2.0%Reduced
Nicholas Investment Partners, LP55,788$4.34M0.32%+3,163+6.0%Added
Verition Fund Management LLC54,319$4.23M0.02%+22,848+72.6%Added
Schroder Investment Management Group52,671$4.11M0.00%−8,969−14.6%Reduced
Comerica Bank49,812$3.88M0.02%−1,611−3.1%Reduced
Russell Investments Group, Ltd.45,977$3.58M0.00%+26,986+142.1%Added
California State Teachers Retirement System45,742$3.56M0.00%+5,043+12.4%Added
Legal & General Group Plc43,428$3.38M0.00%−69−0.2%Reduced
Mirae Asset Global ETFs Holdings Ltd.40,777$3.17M0.00%+13,859+51.5%Added
Dark Forest Capital Management LP39,207$3.05M0.14%+8,155+26.3%Added
Moody Aldrich Partners LLC38,535$3.00M0.56%+9,625+33.3%Added
Marshall Wace, LLP38,022$2.96M0.00%−321,054−89.4%Reduced
Y-Intercept (Hong Kong) Ltd36,429$2.83M0.06%+36,429New
Silverarc Capital Management, LLC34,589$2.69M0.39%+34,589New
State of New Jersey Common Pension Fund D33,538$2.61M0.01%+33,538New
Sio Capital Management, LLC32,235$2.51M0.42%+32,235New